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  1. Article: Minimally Invasive Carpal Tunnel Release: A Technical Note and a 20-Year Retrospective Series.

    Vetrano, Ignazio Gaspare / Devigili, Grazia / Nazzi, Vittoria

    Cureus

    2022  Volume 14, Issue 1, Page(s) e21426

    Abstract: Introduction The surgical treatment of carpal tunnel syndrome (CTS) has been enriched, during the last years, by different minimally invasive techniques to decompress the median nerve at the wrist as the endoscopic approaches or modified open technique. ... ...

    Abstract Introduction The surgical treatment of carpal tunnel syndrome (CTS) has been enriched, during the last years, by different minimally invasive techniques to decompress the median nerve at the wrist as the endoscopic approaches or modified open technique. However, controversy remains about their safety and complication rate. We present the results of our minimally-invasive technique to median nerve release at the wrist. We will discuss the instrumental preoperative assessment, surgical steps, post-operative management, and complications. Methods We retrospectively reviewed clinical and neurophysiological data of all patients admitted at our institution between January 2001 and December 2020 for CTS surgery. The technique, performed under local anesthesia, is based on a single, small, linear transverse incision proximal to the wrist fold. After unsharpened dissection of subcutaneous tissues, a grooved guide is inserted in a slightly medial direction towards the fourth finger; this strategy prevents possible damages of nerve branches that could originate at this level. A second small incision over the guide's tip allows a wide corridor in the context of the ligament. The carpalotome is then inserted into the guide; the two minor wounds are closed with 5-0 prolene sutures. The final result is a wide release of the nerve. Results A total of 1568 operations on 1371 patients were performed using the described technique at our institution. The patients' cohort showed a higher prevalence of women (68%), with a mean age of 56.4 years (range 24-88 years). Paresthesia and numbness of the first three fingers were the most frequent signs and symptoms. All patients were submitted to a preoperative electrophysiological evaluation, which revealed the typical signs of CTS in most patients. The US evaluation of the median nerve at the wrist was a more recent introduction, dating from 2018. In 47 patients, despite an electromyography (EMG) not showing marked neurophysiological signs of severe CTS, the ultrasonographic evaluation was strongly consistent with the clinical diagnosis. In such patients, carpal tunnel release determined the resolution of symptoms. In 99.8% of total cases, we obtained a complete symptoms remission, with the disappearance of acroparesthesia and numbness. Conclusion The use of this technique has become widespread at our institution due to fewer local complications, a very low rate of recurrence, faster functional recovery, and reduced surgical time if compared to traditional open surgery and to endoscopic release too.
    Language English
    Publishing date 2022-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.21426
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  2. Article ; Online: Common peroneal nerve entrapment: the need for a complete assessment before surgery.

    Vetrano, Ignazio G / Devigili, Grazia / Nazzi, Vittoria

    Acta neurochirurgica

    2020  Volume 162, Issue 8, Page(s) 1925–1926

    MeSH term(s) Decompression, Surgical ; Humans ; Nerve Compression Syndromes/surgery ; Peroneal Nerve/surgery ; Peroneal Neuropathies/surgery
    Language English
    Publishing date 2020-05-28
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-020-04410-w
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  3. Article ; Online: Intraoperative Neurophysiologic and Angiographic Techniques to Identify the Posterior Median Sulcus for Midline Myelotomy.

    Iess, Guglielmo / Bonomo, Giulio / Amato, Alessia / Ferroli, Paolo / Devigili, Grazia / Melillo, Ylenia / Schiariti, Marco

    World neurosurgery

    2022  Volume 171, Page(s) 103

    Abstract: Accurate midline myelotomy through the posterior median sulcus (PMS) is the key step to minimize surgical morbidity during intramedullary tumor removal. ...

    Abstract Accurate midline myelotomy through the posterior median sulcus (PMS) is the key step to minimize surgical morbidity during intramedullary tumor removal.
    MeSH term(s) Male ; Humans ; Adult ; Spinal Cord Neoplasms/surgery ; Monitoring, Intraoperative/methods ; Evoked Potentials, Somatosensory/physiology ; Spinal Nerve Roots
    Language English
    Publishing date 2022-11-19
    Publishing country United States
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2022.11.064
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  4. Article ; Online: Lessons from the present: Intraoperative neurophysiological monitoring organization during the COVID-19 pandemic in Lombardy, northern Italy.

    Devigili, Grazia / Eleopra, Roberto / Rinaldo, Sara / Lanteri, Paola

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    2020  Volume 131, Issue 8, Page(s) 2056–2058

    MeSH term(s) COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Critical Care/methods ; Critical Care/organization & administration ; Critical Care/standards ; Electroencephalography/methods ; Electroencephalography/standards ; Humans ; Intraoperative Neurophysiological Monitoring/methods ; Intraoperative Neurophysiological Monitoring/standards ; Italy ; Neurosurgical Procedures/methods ; Neurosurgical Procedures/standards ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Practice Guidelines as Topic ; Quality Improvement
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1463630-x
    ISSN 1872-8952 ; 0921-884X ; 1388-2457
    ISSN (online) 1872-8952
    ISSN 0921-884X ; 1388-2457
    DOI 10.1016/j.clinph.2020.05.002
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  5. Article ; Online: Letter: The Presence and Persistence of Unrealistic Expectations in Patients Undergoing Nerve Surgery.

    Vetrano, Ignazio G / Nazzi, Vittoria / Devigili, Grazia

    Neurosurgery

    2019  Volume 86, Issue 5, Page(s) E469–E470

    MeSH term(s) Humans ; Motivation ; Neurosurgical Procedures ; Pain Measurement ; Patient Satisfaction
    Language English
    Publishing date 2019-12-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyz525
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  6. Article ; Online: Clinical diagnosis and management of small fiber neuropathy: an update on best practice.

    Devigili, Grazia / Cazzato, Daniele / Lauria, Giuseppe

    Expert review of neurotherapeutics

    2020  Volume 20, Issue 9, Page(s) 967–980

    Abstract: Introduction: Small fiber neuropathy (SFN) is a heterogeneous group of disorders affecting thin myelinated Aδ and unmyelinated C fibers. Common symptoms include neuropathic pain and autonomic disturbances, and the typical clinical presentation is that ... ...

    Abstract Introduction: Small fiber neuropathy (SFN) is a heterogeneous group of disorders affecting thin myelinated Aδ and unmyelinated C fibers. Common symptoms include neuropathic pain and autonomic disturbances, and the typical clinical presentation is that of a length-dependent polyneuropathy, although other distributions could be present.
    Area covered: This review focuses on several aspects of SFN including etiology, clinical presentation, diagnostic criteria and tests, management, and future perspectives. Diagnostic challenges are discussed, encompassing the role of accurate and standardized assessment of symptoms and signs and providing clues for the clinical practice. The authors discuss the evidence in support of skin biopsy and quantitative sensory testing as diagnostic tests and present an overview of other diagnostic techniques to assess sensory and autonomic fibers dysfunction. The authors also suggest a systematic approach to the etiology including a set of laboratory tests and genetic examinations of sodium channelopathies and other rare conditions that might drive the therapeutic approach based on underlying cause or symptoms treatment.
    Expert opinion: SFN provides a useful model for neuropathic pain whose known mechanisms and cause could pave the way toward personalized treatments.
    MeSH term(s) Humans ; Small Fiber Neuropathy/diagnosis ; Small Fiber Neuropathy/etiology ; Small Fiber Neuropathy/therapy
    Language English
    Publishing date 2020-07-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2112534-X
    ISSN 1744-8360 ; 1473-7175
    ISSN (online) 1744-8360
    ISSN 1473-7175
    DOI 10.1080/14737175.2020.1794825
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  7. Article ; Online: Aceruloplasminemia: Unique Clinical and MRI Findings in a Patient with a Novel Frameshift Mutation.

    Colucci, Fabiana / Barca, Silvia / Cilia, Roberto / De Franco, Valentino / Elia, Antonio E / Golfrè Andreasi, Nico / Romito, Luigi / Telese, Roberta / Braccia, Arianna / Leta, Valentina / Grisoli, Marina / Panteghini, Celeste / Garavaglia, Barbara / Devigili, Grazia / Eleopra, Roberto

    Movement disorders clinical practice

    2024  

    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Case Reports
    ISSN 2330-1619
    ISSN (online) 2330-1619
    DOI 10.1002/mdc3.14000
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  8. Article ; Online: Pain related to MRgFUS: a merely minor transient adverse event?

    Amami, Paolo / Prioni, Sara / Fusar Poli, Marco / Pascuzzo, Riccardo / Bocchi, Elisa / Golfrè Andreasi, Nico / Devigili, Grazia / Cilia, Roberto / Rinaldo, Sara / Levi, Vincenzo / Ghielmetti, Francesco / Grisoli, Marina / Gemma, Marco / DiMeco, Francesco / Eleopra, Roberto / Piacentini, Sylvie

    Journal of neurology, neurosurgery, and psychiatry

    2024  

    Language English
    Publishing date 2024-04-19
    Publishing country England
    Document type Letter
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2024-333401
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  9. Article ; Online: Lipomatosis of nerve and overgrowth syndrome: an intriguing and still unclear correlation.

    Vetrano, Ignazio G / Sconfienza, Luca Maria / Devigili, Grazia / Nazzi, Vittoria

    Acta neurochirurgica

    2019  Volume 161, Issue 6, Page(s) 1085–1086

    MeSH term(s) Humans ; Lipomatosis ; Syndrome
    Language English
    Publishing date 2019-05-02
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-019-03916-2
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  10. Article: Lessons from the present: Intraoperative neurophysiological monitoring organization during the COVID-19 pandemic in Lombardy, northern Italy

    Devigili, Grazia / Eleopra, Roberto / Rinaldo, Sara / Lanteri, Paola

    Clin. neurophysiol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32456880
    Database COVID19

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