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  1. Article ; Online: The Dark Side of Chiari Malformation.

    Spina, Alfio / Mortini, Pietro

    World neurosurgery

    2023  Volume 172, Page(s) 43–45

    MeSH term(s) Humans ; Arnold-Chiari Malformation/diagnostic imaging ; Arnold-Chiari Malformation/surgery ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.01.112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: In Reply to the Letter to the Editor Regarding "The Dark Side of Chiari Malformation".

    Spina, Alfio / Mortini, Pietro

    World neurosurgery

    2023  Volume 178, Page(s) 281

    MeSH term(s) Humans ; Arnold-Chiari Malformation/surgery ; Decompression, Surgical
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.08.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Update on Multidisciplinary Management of Surgical Neurovascular Pathologies.

    Luzzi, Sabino / Spina, Alfio / Giotta Lucifero, Alice

    Frontiers in surgery

    2022  Volume 9, Page(s) 923493

    Language English
    Publishing date 2022-06-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.923493
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  4. Article ; Online: Letter to the Editor. Management of hyperostotic spheno-orbital meningiomas.

    Spina, Alfio / Boari, Nicola / Mortini, Pietro

    Journal of neurosurgery

    2021  , Page(s) 1–2

    Language English
    Publishing date 2021-08-13
    Publishing country United States
    Document type Journal Article ; Letter
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/2021.4.JNS21952
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.135: Show issues Location:
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  5. Article ; Online: Gamma Knife radiosurgery for central neurocytoma: a quantitative systematic review and metanalysis.

    Spina, Alfio / Garbin, Enrico / Albano, Luigi / Bisoglio, Andrea / Boari, Nicola / Mortini, Pietro

    Neurosurgical review

    2024  Volume 47, Issue 1, Page(s) 64

    Abstract: Central neurocytomas (CN) are rare tumors within the central nervous system. Originating from the septum pellucidum and subependymal cells, they are typically found in the third and lateral ventricles. For this reason, they may lead to hydrocephalus and ... ...

    Abstract Central neurocytomas (CN) are rare tumors within the central nervous system. Originating from the septum pellucidum and subependymal cells, they are typically found in the third and lateral ventricles. For this reason, they may lead to hydrocephalus and increased intracranial pressure. CNs are generally benign lesions that exhibit locally aggressive behavior and a high recurrence rate. Complete surgical resection is the preferred treatment; however, due to their anatomical location, this is often not feasible. Based on these findings, Gamma Knife radiosurgery (GKRS) has been introduced for managing both residual and recurrent tumors and as an initial therapy in selected cases. This study aimed to systematically review the available knowledge regarding GKRS for CN. A systematic investigation of the scientific literature was undertaken through an exhaustive search across prominent databases, including PubMed, Web of Science, and Google Scholar, by employing precise MeSH terms such as "Central neurocytoma," "Radiosurgery," "Gamma Knife," and "Stereotactic Radiosurgery." A comprehensive quantitative systematic review and meta-analysis were meticulously conducted, focusing on cases of CN treated with GKRS for a thorough evaluation of outcomes and efficacy. Seventeen articles, including 289 patients, met the inclusion criteria. Random effects meta-analysis estimates for disease control and local tumor control were 90% (95% CI 87-93%; I2 = 0%, p < 0.74) and 94% (95% CI 92-97%; I2 = 0%, p < 0.98), respectively. When considering only studies with at least 5 years of follow-up, progression-free survival was 89% (95% CI 85-94%; I2 = 0.03%, p < 0.74). The mean clinical control rate was 96%. This systematic review and meta-analysis confirmed the safety and efficacy of GKRS in managing CN.
    MeSH term(s) Humans ; Radiosurgery ; Neurocytoma ; Central Nervous System ; Databases, Factual ; Hydrocephalus
    Language English
    Publishing date 2024-01-24
    Publishing country Germany
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-024-02301-7
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    Zs.A 1445: Show issues Location:
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  6. Article: Quantitative EEG for early differential diagnosis of dementia with Lewy bodies.

    Iannaccone, Sandro / Houdayer, Elise / Spina, Alfio / Nocera, Gianluca / Alemanno, Federica

    Frontiers in psychology

    2023  Volume 14, Page(s) 1150540

    Abstract: Introduction: Differentiating between the two most common forms of dementia, Alzheimer's dementia and dementia with Lewy bodies (DLB) remains difficult and requires the use of invasive, expensive, and resource-intensive techniques. We aimed to ... ...

    Abstract Introduction: Differentiating between the two most common forms of dementia, Alzheimer's dementia and dementia with Lewy bodies (DLB) remains difficult and requires the use of invasive, expensive, and resource-intensive techniques. We aimed to investigate the sensitivity and specificity of electroencephalography quantified using the statistical pattern recognition method (qEEG-SPR) for identifying dementia and DLB.
    Methods: Thirty-two outpatients and 16 controls underwent clinical assessment (by two blinded neurologists), EEG recording, and a 6-month follow-up clinical assessment. EEG data were processed using a qEEG-SPR protocol to derive a Dementia Index (positive or negative) and DLB index (positive or negative) for each participant which was compared against the diagnosis given at clinical assessment. Confusion matrices were used to calculate sensitivity, specificity, and predictive values for identifying dementia and DLB specifically.
    Results: Clinical assessment identified 30 cases of dementia, 2 of which were diagnosed clinically with possible DLB, 14 with probable DLB and DLB was excluded in 14 patients. qEEG-SPR confirmed the dementia diagnosis in 26 out of the 32 patients and led to 6.3% of false positives (FP) and 9.4% of false negatives (FN). qEEG-SPR was used to provide a DLB diagnosis among patients who received a positive or inconclusive result of Dementia index and led to 13.6% of FP and 13.6% of FN. Confusion matrices indicated a sensitivity of 80%, a specificity of 89%, a positive predictive value of 92%, a negative predictive value of 72%, and an accuracy of 83% to diagnose dementia. The DLB index showed a sensitivity of 60%, a specificity of 90%, a positive predictive value of 75%, a negative predictive value of 81%, and an accuracy of 75%. Neuropsychological scores did not differ significantly between DLB and non- DLB patients. Head trauma or story of stroke were identified as possible causes of FP results for DLB diagnosis.
    Conclusion: qEEG-SPR is a sensitive and specific tool for diagnosing dementia and differentiating DLB from other forms of dementia in the initial state. This non-invasive, low-cost, and environmentally friendly method is a promising diagnostic tool for dementia diagnosis which could be implemented in local care settings.
    Language English
    Publishing date 2023-04-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1150540
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  7. Article ; Online: Letter to the Editor. Earlier radiosurgery is related to better outcome in trigeminal neuralgia.

    Spina, Alfio / Boari, Nicola / Mortini, Pietro

    Journal of neurosurgery

    2020  Volume 135, Issue 1, Page(s) 329–330

    Language English
    Publishing date 2020-11-13
    Publishing country United States
    Document type Journal Article ; Letter
    ZDB-ID 3089-2
    ISSN 1933-0693 ; 0022-3085
    ISSN (online) 1933-0693
    ISSN 0022-3085
    DOI 10.3171/2020.9.JNS203342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.135: Show issues Location:
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  8. Article ; Online: Response to: Nutritional strategies for the rehabilitation of COVID-19 patients.

    Brugliera, Luigia / Spina, Alfio / Giordani, Alessandra / Iannaccone, Sandro

    European journal of clinical nutrition

    2020  Volume 75, Issue 4, Page(s) 731–732

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-11-09
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/s41430-020-00801-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 1045: Show issues Location:
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  9. Article: Factors Affecting the Nutritional, Health, and Technological Quality of Durum Wheat for Pasta-Making: A Systematic Literature Review.

    Zingale, Silvia / Spina, Alfio / Ingrao, Carlo / Fallico, Biagio / Timpanaro, Giuseppe / Anastasi, Umberto / Guarnaccia, Paolo

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 3

    Abstract: Durum wheat is one of the most important food sources in the world, playing a key role in human nutrition, as well as in the economy of the different countries in which its production areas are concentrated. Its grain also represents a staple and highly ... ...

    Abstract Durum wheat is one of the most important food sources in the world, playing a key role in human nutrition, as well as in the economy of the different countries in which its production areas are concentrated. Its grain also represents a staple and highly versatile ingredient in the development of health foods. Nonetheless, the aspects determining durum wheat's health quality and their interactions are many, complex, and not entirely known. Therefore, the present systematic literature review aims at advancing the understanding of the relationships among nutritional, health, and technological properties of durum wheat grain, semolina, and pasta, by evaluating the factors that, either positively or negatively, can affect the quality of the products. Scopus, Science Direct, and Web of Science databases were systematically searched utilising sets of keywords following the PRISMA guidelines, and the relevant results of the definitive 154 eligible studies were presented and discussed. Thus, the review identified the most promising strategies to improve durum wheat quality and highlighted the importance of adopting multidisciplinary approaches for such purposes.
    Language English
    Publishing date 2023-01-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12030530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Lupin as Ingredient in Durum Wheat Breadmaking: Physicochemical Properties of Flour Blends and Bread Quality.

    Spina, Alfio / Summo, Carmine / Timpanaro, Nicolina / Canale, Michele / Sanfilippo, Rosalia / Amenta, Margherita / Strano, Maria Concetta / Allegra, Maria / Papa, Martina / Pasqualone, Antonella

    Foods (Basel, Switzerland)

    2024  Volume 13, Issue 5

    Abstract: The popularity of adding pulse flours to baked goods is growing rapidly due to their recognised health benefits. In this study, increasing amounts (3, 7, 10, and 15%) of white lupin flour ( ...

    Abstract The popularity of adding pulse flours to baked goods is growing rapidly due to their recognised health benefits. In this study, increasing amounts (3, 7, 10, and 15%) of white lupin flour (
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods13050807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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