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  1. Article ; Online: Cumulative housing cost burden exposures and disadvantages to children's well-being and health.

    Hess, Chris / Colburn, Gregg / Allen, Ryan / Crowder, Kyle

    Social science research

    2024  Volume 119, Page(s) 102984

    Abstract: Housing affordability is a growing challenge for households in the United States and other developed countries. Prolonged exposure to housing cost burden can have damaging effects on households, and, in particular, children. These burdens can exacerbate ... ...

    Abstract Housing affordability is a growing challenge for households in the United States and other developed countries. Prolonged exposure to housing cost burden can have damaging effects on households, and, in particular, children. These burdens can exacerbate parental stress, reduce investments in children and expose households to greater neighborhood disadvantage. In this study, we use national survey data to assess whether cumulative housing cost burden exposure is associated with disadvantages to children's well-being and health. We observe that long-term exposures are linked to lower achievement in math and reading standardized test scores, as well as higher levels of behavior problems. Moreover, we identify that three mechanisms--caregiver distress, economic strain, and neighborhood disadvantage--operate as mediating pathways for these disadvantages to different degrees between these three outcomes. Overall, our study highlights how the dimension of time is increasingly important to our understanding of the challenges that families face related to housing affordability.
    MeSH term(s) Child ; Humans ; Housing ; Problem Behavior
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ISSN 1096-0317
    ISSN (online) 1096-0317
    DOI 10.1016/j.ssresearch.2024.102984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An Updated Review of Hypertrophic Scarring.

    Mony, Manjula P / Harmon, Kelly A / Hess, Ryan / Dorafshar, Amir H / Shafikhani, Sasha H

    Cells

    2023  Volume 12, Issue 5

    Abstract: Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. In this review article, we provide an overview of normal (acute) wound ... ...

    Abstract Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. In this review article, we provide an overview of normal (acute) wound healing phases (hemostasis, inflammation, proliferation, and remodeling). We next discuss the dysregulated and/or impaired mechanisms in wound healing phases that are associated with HTS development. We next discuss the animal models of HTS and their limitations, and review the current and emerging treatments of HTS.
    MeSH term(s) Animals ; Cicatrix, Hypertrophic/pathology ; Wound Healing ; Models, Animal ; Inflammation ; Extracellular Matrix/pathology
    Language English
    Publishing date 2023-02-21
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12050678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Health Numeracy and Relative Risk Comprehension in Perioperative Patients and Physicians.

    Hayter, Ryan R / Hess, Aaron S

    Anesthesia and analgesia

    2020  Volume 131, Issue 2, Page(s) 579–585

    Abstract: Background: Helping patients to understand relative risks is challenging. In discussions with patients, physicians often use numbers to describe hazards, make comparisons, and establish relevance. Patients with a poor understanding of numbers-poor " ... ...

    Abstract Background: Helping patients to understand relative risks is challenging. In discussions with patients, physicians often use numbers to describe hazards, make comparisons, and establish relevance. Patients with a poor understanding of numbers-poor "health numeracy"-also have difficulty making decisions and coping with chronic conditions. Although the importance of "health literacy" in perioperative populations is recognized, health numeracy has not been well studied. Our aim was to compare understanding of numbers, risk, and risk modification between a patient population awaiting surgery under general anesthesia and attending physicians at the same center.
    Methods: We performed a single-center cross-sectional survey study to compare patients' and physicians' health numeracy. The study instrument was based on the Schwartz-Lipkus survey and included 3 simple health numeracy questions and 2 risk reduction questions in the anesthesiology domain. The survey was mailed to patients over the age of 18 scheduled for elective surgery under general anesthesia between June and September 2019, as well as attending physicians at the study center.
    Results: Two hundred thirteen of 502 (42%) patient surveys sent and 268 of 506 (53%) physician surveys sent were returned. Median patient score was 4 of 5, but 32% had a score of ≤3. Patients significantly overestimated their total scores by an average of 0.5 points (estimated [mean ± standard deviation (SD)] = 4.3 ± 1.2 vs actual 3.8 ± 1.3; P < .001). Health numeracy was significantly associated with higher educational level (gamma = 0.351; P < .001) and higher-income level (gamma = 0.397; P < .001). Physicians' health numeracy was significantly higher than the patients' (median [interquartile range {IQR}] = 5 [4-5] vs 4 [3-5]; P < .001). There was no significant difference between physicians' self-estimated and actual total numeracy score (mean ± SD = 4.8 ± 0.6 vs 4.7 ± 0.6; P = .372). Simple health numeracy (questions 1-3) was predictive of correct risk reduction responses (questions 4, 5) for both patients (gamma = 0.586; P < .001) and physicians (gamma = 0.558; P = .006).
    Conclusions: Patients had poor health numeracy compared to physicians and tended to overrate their abilities. A small proportion of physicians also had poor numeracy. Poor health numeracy was associated with incomprehension of risk modification, suggesting that some patients may not understand treatment efficacy. These disparities suggest a need for further inquiry into how to improve patient comprehension of risk modification.
    MeSH term(s) Adult ; Aged ; Comprehension ; Cross-Sectional Studies ; Female ; Health Literacy/standards ; Humans ; Male ; Middle Aged ; Patient Participation/psychology ; Perioperative Care/psychology ; Perioperative Care/standards ; Physicians/psychology ; Physicians/standards ; Risk Factors ; Surveys and Questionnaires/standards
    Language English
    Publishing date 2020-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000004816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Medical School Without Walls: 50 Years of Regional Campuses at Indiana University School of Medicine.

    Wallach, Paul M / Birnbaum, Deborah R / Ryan, Elizabeth R / Pieczko, Brandon T / Hess, Jay L

    Academic medicine : journal of the Association of American Medical Colleges

    2022  Volume 97, Issue 12, Page(s) 1765–1772

    Abstract: The history of Indiana University School of Medicine (IUSM) dates to 1871, when Indiana Medical College entered into an affiliation with Indiana University in Bloomington to offer medical education. In 1971, the Indiana General Assembly passed a bill to ... ...

    Abstract The history of Indiana University School of Medicine (IUSM) dates to 1871, when Indiana Medical College entered into an affiliation with Indiana University in Bloomington to offer medical education. In 1971, the Indiana General Assembly passed a bill to create and fund a distributed model for medical education for which IUSM was responsible, an innovative approach to implementing a statewide medical education program. IUSM became one of the first U.S. medical schools to implement what is today known as a regional medical campus model. This regional medical campus system has permitted IUSM to expand enrollment based on national and local concerns about physician shortages, increase access to care locally, support expansion of graduate medical education, and provide opportunities for research and scholarship by faculty and students statewide. This effort was made possible by partnerships with other universities and health care systems across the state and the support of local community and state leaders. The model is a forward-thinking and cost-effective way to educate physicians for service in the state of Indiana and is applicable to others. This article highlights milestones in IUSM's 50-year history of regional medical education, describes the development of the regional medical campus model, recognizes significant achievements over the years, shares lessons learned, and discusses considerations for the future of medical education.
    MeSH term(s) Humans ; Schools, Medical ; Universities ; Indiana ; Medicine ; Education, Medical
    Language English
    Publishing date 2022-08-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000004940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The buffering role of higher romantic relationship satisfaction on the association of hazardous drinking with PTSD and depression symptoms among female military service members/veterans.

    Blais, Rebecca K / Hess, Ryan A / Serang, Sarfaraz

    Addictive behaviors

    2021  Volume 123, Page(s) 107081

    Abstract: Studies show that more positive relationship satisfaction can mitigate the effects of posttraumatic stress disorder (PTSD) and depression severity on hazardous drinking in military samples. However, past studies were not circumscribed to female service ... ...

    Abstract Studies show that more positive relationship satisfaction can mitigate the effects of posttraumatic stress disorder (PTSD) and depression severity on hazardous drinking in military samples. However, past studies were not circumscribed to female service members/veterans (SM/V), who represent the fastest growing demographic in the military. Moreover, studies did not examine moderators of specific symptom clusters of PTSD and depression with hazardous drinking. Indeed, recent studies have shown that the more depressive and cognitive clusters are associated with greater dysfunction. The current study extended this literature in a convenience sample of 584 female SM/V who completed self-report measures of hazardous drinking, PTSD, depression, and relationship satisfaction. PTSD or depression severity, relationship satisfaction, and their interaction, were examined as correlates of hazardous drinking after accounting for relationship, demographic, and military characteristics. For both overall PTSD and depression severity, higher relationship satisfaction weakened their association with hazardous drinking. Such results were consistent when global scores were replaced with PTSD-related negative alterations in cognitions and mood and somatic depression symptom clusters, but not for PTSD-related dysphoric arousal, anhedonia, or non-somatic depression symptom clusters. Findings suggest that to lessen the association of PTSD or depressive symptoms with problematic drinking, interventions aimed at improving relationship satisfaction may be worth considering among women in relationships. Moreover, symptom cluster analyses show that the cognitive and depressive components of PTSD, as well as the physical symptoms of depression, are most problematic, pinpointing specific areas of function on which to intervene.
    Language English
    Publishing date 2021-08-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 197618-7
    ISSN 1873-6327 ; 0306-4603
    ISSN (online) 1873-6327
    ISSN 0306-4603
    DOI 10.1016/j.addbeh.2021.107081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: An Updated Review of Hypertrophic Scarring

    Manjula P. Mony / Kelly A. Harmon / Ryan Hess / Amir H. Dorafshar / Sasha H. Shafikhani

    Cells, Vol 12, Iss 678, p

    2023  Volume 678

    Abstract: Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. In this review article, we provide an overview of normal (acute) wound ... ...

    Abstract Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with excessive deposition of extracellular matrix and connective tissue at the site of injury. In this review article, we provide an overview of normal (acute) wound healing phases (hemostasis, inflammation, proliferation, and remodeling). We next discuss the dysregulated and/or impaired mechanisms in wound healing phases that are associated with HTS development. We next discuss the animal models of HTS and their limitations, and review the current and emerging treatments of HTS.
    Keywords normal (acute) wound healing ; hypertrophic scar ; keloids ; animal models ; treatments ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Failure of

    Hess, Kyle A / Kooda, Kirstin / Shirley, Joshua D / Schuetz, Audrey N / Abu Saleh, Omar / Stevens, Ryan W

    Antimicrobial agents and chemotherapy

    2023  , Page(s) e0043723

    Abstract: Genotypic testing ... ...

    Abstract Genotypic testing for
    MeSH term(s) Humans ; Aged ; Oxacillin/pharmacology ; Oxacillin/therapeutic use ; Staphylococcus aureus/genetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacterial Proteins/genetics ; Microbial Sensitivity Tests ; Staphylococcal Infections/drug therapy ; Endocarditis, Bacterial/drug therapy ; Polymerase Chain Reaction ; Endocarditis ; Methicillin-Resistant Staphylococcus aureus/genetics ; Penicillin-Binding Proteins/genetics
    Chemical Substances Oxacillin (UH95VD7V76) ; Anti-Bacterial Agents ; Bacterial Proteins ; Penicillin-Binding Proteins
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00437-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Racial disparity in exposure to housing cost burden in the United States: 1980-2017.

    Hess, Chris / Colburn, Gregg / Crowder, Kyle / Allen, Ryan

    Housing studies

    2020  Volume 37, Issue 10, Page(s) 1821–1841

    Abstract: This paper uses the Panel Study of Income Dynamics to analyze Black-White differences in housing cost burden exposure among renter households in the United States from 1980 to 2017, expanding understanding of this phenomenon in two respects. Specifically, ...

    Abstract This paper uses the Panel Study of Income Dynamics to analyze Black-White differences in housing cost burden exposure among renter households in the United States from 1980 to 2017, expanding understanding of this phenomenon in two respects. Specifically, we document how much this racial disparity changed among renters over almost four decades and identify how much factors associated with income or housing costs explain Black-White inequality in exposure to housing cost burden. For White households, the net contribution of household, neighborhood, and metropolitan covariates accounts for much of the change in the probability of housing cost burden over time. For Black households, however, the probability of experiencing housing cost burden continued to rise throughout the period of this study, even after controlling for household, neighborhood, and metropolitan covariates. This suggests that unobserved variables like racial discrimination, social networks or employment quality might explain the increasing disparity in cost burden among for Black and White households in the U.S.
    Language English
    Publishing date 2020-08-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476302-3
    ISSN 1466-1810 ; 0267-3037
    ISSN (online) 1466-1810
    ISSN 0267-3037
    DOI 10.1080/02673037.2020.1807473
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cerebral Proliferative Angiopathy Presenting as Subdural Hematoma: A Case Report and Systematic Literature Review.

    Hess, Ryan M / Zhang, Jeff F / Cappuzzo, Justin M / Bregy, Amade / Levy, Elad I

    World neurosurgery

    2022  Volume 164, Page(s) 281–289

    Abstract: Cerebral proliferative angiopathy (CPA) is a rare cerebrovascular pathology that presents with unique clinical features due to distinct histologic, angiographic, and pathophysiologic characteristics that separate it from classical arteriovenous ... ...

    Abstract Cerebral proliferative angiopathy (CPA) is a rare cerebrovascular pathology that presents with unique clinical features due to distinct histologic, angiographic, and pathophysiologic characteristics that separate it from classical arteriovenous malformation. The disorder is characterized by uncontrolled angiogenesis in which functional brain parenchyma is interspersed with abnormal vascular channels without a distinct nidus. Common presenting symptoms include headache, seizures, and stroke-like symptoms. Hemorrhagic presentations are rare in contrast to the typical presentations of classical arteriovenous malformation. Here, we report a young woman with a history of a suspected connective tissue disorder who presented to the emergency department with worsening headaches in a delayed fashion after experiencing minor head trauma and was found to have a left-sided subdural hematoma. Angiography confirmed a diagnosis of CPA after abnormal cortical vasculature was noted during the patient's craniotomy. A systematic review of CPA cases described in the literature was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, with the findings discussed.
    MeSH term(s) Cerebral Angiography ; Cerebrovascular Disorders ; Female ; Headache ; Hematoma, Subdural/diagnostic imaging ; Hematoma, Subdural/etiology ; Hematoma, Subdural/surgery ; Humans ; Intracranial Arteriovenous Malformations/complications ; Intracranial Arteriovenous Malformations/diagnostic imaging ; Intracranial Arteriovenous Malformations/surgery
    Language English
    Publishing date 2022-05-27
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review ; Systematic Review
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2022.05.096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effects of Different Hay Feeders, Availability of Roughage on Abnormal Behaviors and Cortisol Circadian Rhythm in Horses Kept in Dry Lots.

    Carvalho Seabra, Jéssica / Hess, Tanja / Martinez do Vale, Marcos / Spercoski, Katherinne Maria / Brooks, Ryan / Dittrich, João Ricardo

    Journal of equine veterinary science

    2023  Volume 130, Page(s) 104911

    Abstract: Free choice forage could be the best option regarding horses' welfare but can lead to increased body weight (BW), and waste of hay. Automatic box feeders (BF) and slow feeders (SF) decrease food waste, but it is unknown how these affect the horses' time- ... ...

    Abstract Free choice forage could be the best option regarding horses' welfare but can lead to increased body weight (BW), and waste of hay. Automatic box feeders (BF) and slow feeders (SF) decrease food waste, but it is unknown how these affect the horses' time-budget (TB). This study compared the effects of feeding free choice hay (FC), to a SF and an automated BF on the horses' cortisol circadian rhythm (CCR) and behavior by 24-hours continuous behavioral sampling (CBS). The study was designed as a 3 × 3 Latin square design with 15 polo horses divided into 3 groups, for 15 days on each treatment. Every 15 days, BW was assessed, blood collected for CCR analysis, the behavior recorded during the last 24 hours of the last day of each treatment and the video analyzed with CBS. Time spent on all behaviors was evaluated and used for the determination of the animals' TB. The effects of the different feeders were analyzed with ANOVA. FC horses consumed and wasted more hay daily (16.6 ± 0.5kg) (P < .001), compared with BF (10.4 ± 0.5 kg), and SF (9.30 ± 0.45 kg). FC horses had higher weight gain (P < .001, 23.5 ± 4.6kg), compared to BF (1.2 ± 5.7 kg) and SF (0.37 ± 4.6) kg. FC and SF horses spent more than 50% of the TB foraging, generating a TB similar to grazing horses. BF horses spent less time eating (P < .001), increasing time spent standing, sniffing the ground, and practicing coprophagy (P < .050). BF horses showed the highest aggression (P < .043). CCR was not different among treatments.
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2102631-2
    ISSN 1542-7412 ; 0737-0806
    ISSN (online) 1542-7412
    ISSN 0737-0806
    DOI 10.1016/j.jevs.2023.104911
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