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  1. Book ; Online: Enzymes and Biocatalysis

    Kuo, Chia-Hung / Kuo, Chia-Hung / Huang, Chun-Yung / Shieh, Chwen-Jen / Dong, Cheng-Di

    2022  

    Keywords Research & information: general ; Biology, life sciences ; enzyme identification ; flavin-dependent halogenases ; bromination ; metagenome screening ; bacterial consortia of Botryococcus braunii ; bioinformatics ; animal nutrition ; enzyme ; animal feed ; zootechnical additive ; digestibility ; antinutritional factors ; Aspergillus ; protease ; sequential fermentation ; kinetics ; thermodynamics ; lipase ; immobilization ; Aspergillus japonicus ; montmorillonite KSF ; Bambusa oldhamii ; phenylalanine ammonia-lyase ; phenylalanine/tyrosine ammonia-lyase ; substrate specificity ; plant secondary metabolism ; phenylpropanoid ; small molecule ; dynamic kinetic resolution ; levetiracetam ; nitrile hydratase ; amino amide ; amino nitrile ; HCV ; NS3 ; protein expression ; diagnosis ; helicase ; biocatalyst ; cyanide hydratase ; nitrilase ; Exidia glandulosa ; industrial effluent ; cokemaking ; electroplating ; wastewater treatment ; free cyanide ; formamide ; α-amylase ; pullulanase ; Clavispora lusitaniae ; purification ; enzyme characterization ; adsorption of protein mixtures ; BEICP ; EICP ; MICP ; hydrophobic soils ; Sporosarcina pasteurii ; soil ; water ; metagenomics ; enzymes ; biodiversity ; docosahexaenoic acid ethyl ester ; eicosapentaenoic acid ethyl ester ; packed-bed reactor ; ultrasonication ; mass transfer ; solvent-free ; ethyl acetate ; trypsin ; calcium-binding ; enzyme engineering ; n/a
    Language 0|e
    Size 1 electronic resource (244 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021621658
    ISBN 9783036554129 ; 3036554122
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Enhancing EEG Artifact Removal Efficiency by Introducing Dense Skip Connections to IC-U-Net.

    Chang, Kong-Yi / Huang, Yung-Chia / Chuang, Chun-Hsiang

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2023  Volume 2023, Page(s) 1–4

    Abstract: Electroencephalographic (EEG) data is considered contaminated with various types of artifacts. Deep learning has been successfully applied to developing EEG artifact removal techniques to increase the signal-to-noise ratio (SNR) and enhance brain- ... ...

    Abstract Electroencephalographic (EEG) data is considered contaminated with various types of artifacts. Deep learning has been successfully applied to developing EEG artifact removal techniques to increase the signal-to-noise ratio (SNR) and enhance brain-computer interface performance. Recently, our research team has proposed an end-to-end UNet-based EEG artifact removal technique, IC-U-Net, which can reconstruct signals against various artifacts. However, this model suffers from being prone to overfitting with a limited training dataset size and demanding a high computational cost. To address these issues, this study attempted to leverage the architecture of UNet++ to improve the practicability of IC-U-Net by introducing dense skip connections in the encoder-decoder architecture. Results showed that this proposed model obtained superior SNR to the original model with half the number of parameters. Also, this proposed model achieved comparable convergency using a quarter of the training data size.
    MeSH term(s) Artifacts ; Algorithms ; Electroencephalography/methods ; Signal-To-Noise Ratio ; Brain-Computer Interfaces
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC40787.2023.10340520
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Chia chʻu hsüeh hsing chi chʻi ying yung

    Tsou, I / Chʻen, Shih-chʻüan / Huang, Lu-sheng

    1990  

    Title variant Jiaxu xuexing jiqi yingyung ; Blood groups and their applications in domestic animals
    Author's details Tsou I, Chʻen Shih-chʻüan, Huang Lu-sheng chu
    Keywords Blood groups in animals. ; Animal genetics.
    Language Chinese
    Size 2, 2, 294 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan.
    Publisher Shan-tung kʻo hsüeh chi shu chʻu pan she ; Shan-tung sheng hsin hua shu tien fa hsing
    Publishing place Chi-nan shih
    Document type Book
    Note Preface in English.
    ISBN 7533107217 ; 9787533107215
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Phytochemicals from

    Chen, Yung-Chia / Chia, Yi-Chen / Huang, Bu-Miin

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 17

    Abstract: ... ...

    Abstract Polyalthia
    MeSH term(s) Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Humans ; Molecular Structure ; Phytochemicals/chemistry ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Polyalthia/chemistry
    Chemical Substances Anti-Inflammatory Agents ; Antineoplastic Agents, Phytogenic ; Antioxidants ; Phytochemicals
    Language English
    Publishing date 2021-09-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26175369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  5. Article: Incidental finding of situs ambiguus in a middle-aged woman.

    Huang, Yung-Chia / Lee, Shih-Wei / Wu, Shih-Hsin / Chen, Mei-Yin

    Respirology case reports

    2022  Volume 10, Issue 9, Page(s) e01018

    Abstract: Situs ambiguus is a rare congenital abnormality with outcomes ranging from asymptomatic to fatal. Here we present a woman with an incidental finding of situs ambiguus hinted by her chest radiograph. This case highlights the importance of actively seeking ...

    Abstract Situs ambiguus is a rare congenital abnormality with outcomes ranging from asymptomatic to fatal. Here we present a woman with an incidental finding of situs ambiguus hinted by her chest radiograph. This case highlights the importance of actively seeking diagnosis when right sub-diaphragmic air is noted when viewing a chest radiograph.
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2750180-2
    ISSN 2051-3380
    ISSN 2051-3380
    DOI 10.1002/rcr2.1018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Free Radical-Scavenging, Anti-Inflammatory, and Antibacterial Activities of Water and Ethanol Extracts Prepared from Compressional-Puffing Pretreated Mango (Mangifera indica L.) Peels

    Huang, Chun-Yung / Kuo, Chia-Hung

    Journal of food quality, 2018:1025387

    2018  

    Abstract: During the processing of mango, a huge amount of peel is generated, which is environmentally problematic. In the present study, a compressional-puffing process was adopted to pretreat the peels of various mango cultivars, and then the bioactive compounds ...

    Abstract During the processing of mango, a huge amount of peel is generated, which is environmentally problematic. In the present study, a compressional-puffing process was adopted to pretreat the peels of various mango cultivars, and then the bioactive compounds of mango peels were extracted by water or ethanol. The phenolic compound compositions as well as the free radical-scavenging, anti-inflammatory, and antibacterial activities of water extract (WE) and ethanol extract (EE) from nonpuffed (NP) and compressional-puffed (CP) mango peels were further evaluated. It was found that compressional-puffing could increase the yield of extracts obtained from most mango varieties and could augment the polyphenol content of extracts from Jinhwang and Tainoung number 1 (TN1) cultivars. The WE and EE from TN1 exhibited the highest polyphenol content and the greatest free radical-scavenging activities among the mango cultivars tested. Seven phenolic compounds (gallic acid, pyrogallol, chlorogenic acid, p-hydroxybenzoic acid, p-coumaric acid, ECG, and CG) were detected in CPWE (compressional-puffed water extract) and CPEE (compressional-puffed ethanol extract) from TN1, and antioxidant stability of both CPWE and CPEE was higher than that of vitamin C. Further biological experiments revealed that CPEE from TN1 possessed the strongest anti-inflammatory and antibacterial activities, and thus it is recommended as a multibioactive agent, which may have applications in the food, cosmetic, and nutraceutical industries.
    Language English
    Document type Article
    Database Repository for Life Sciences

    Full text online

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  7. Article ; Online: Phytochemicals from Polyalthia Species

    Yung-Chia Chen / Yi-Chen Chia / Bu-Miin Huang

    Molecules, Vol 26, Iss 5369, p

    Potential and Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Chemoprevention Activities

    2021  Volume 5369

    Abstract: Polyalthia belong to the Annonaceae family and are a type of evergreen tree distributed across many tropical and subtropical regions. Polyalthia species have been used long term as indigenous medicine to treat certain diseases, including fever, diabetes, ...

    Abstract Polyalthia belong to the Annonaceae family and are a type of evergreen tree distributed across many tropical and subtropical regions. Polyalthia species have been used long term as indigenous medicine to treat certain diseases, including fever, diabetes, infection, digestive disease, etc. Recent studies have demonstrated that not only crude extracts but also the isolated pure compounds exhibit various pharmacological activities, such as anti-oxidant, anti-microbial, anti-tumor, anti-cancer, etc. It is known that the initiation of cancer usually takes several years and is related to unhealthy lifestyle, as well as dietary and environmental factors, such as stress, toxins and smoking. In fact, natural or synthetic substances have been used as cancer chemoprevention to delay, impede, or even stop cancer growing. This review is an attempt to collect current available phytochemicals from Polyalthia species , which exhibit anti-cancer potentials for chemoprevention purposes, providing directions for further research on the interesting agents and possible clinical applications.
    Keywords Polyalthia ; phytochemical ; chemoprevention ; anti-tumor ; anti-cancer ; anti-microbial ; Organic chemistry ; QD241-441
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions.

    Chen, Yung-Chia / Huang, Bu-Miin

    Journal of visualized experiments : JoVE

    2019  , Issue 145

    Abstract: The hormone which the adrenal cortex secretes is vital for animals against stress and diseases. The method described here is the procedure of primary cultured rat adrenal cells and related functional assays (immunofluorescence staining of lipid droplet ... ...

    Abstract The hormone which the adrenal cortex secretes is vital for animals against stress and diseases. The method described here is the procedure of primary cultured rat adrenal cells and related functional assays (immunofluorescence staining of lipid droplet surface protein, as well as corticosterone analysis). Unlike an in vivo model, the variation of interexperiments in adrenal monolayer cultures is less and the experimental condition is easy to control. Besides, the source of rats is also more stable than other animals, like bovine ones. There are also several human adrenal cell lines (NCI-H295, NCI-H295R, SW13, etc.) that can be used in adrenal studies. However, the steroid production of these lines will still be influenced by numerous factors, which include serum lot number, passage number, mutant/loss of distinct genes, etc. Except for lacking 17α-hydroxylase, the primary culture of rat adrenocortical cells is a better and more convenient technique for studying adrenal physiology. In summary, primary rat adrenal cultures could be a good in vitro platform for researchers to investigate the mechanisms of the reagent of interest in the adrenal gland system.
    MeSH term(s) Adrenal Cortex/cytology ; Adrenocorticotropic Hormone/pharmacology ; Animals ; Cells, Cultured ; Corticosterone/metabolism ; Female ; Male ; Rats, Sprague-Dawley ; Steroids/biosynthesis
    Chemical Substances Steroids ; Adrenocorticotropic Hormone (9002-60-2) ; Corticosterone (W980KJ009P)
    Language English
    Publishing date 2019-03-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/59016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Nasal high flow cannula maybe prioritized in treating patients suffering from COVID-19?

    Huang, Yung-Chia / Cheng, Chien-Yu / Lin, Chou-Jui / Lee, Shih-Wei

    Journal of the Formosan Medical Association = Taiwan yi zhi

    2021  Volume 120, Issue 11, Page(s) 2048–2049

    MeSH term(s) COVID-19 ; Cannula ; Humans ; Oxygen Inhalation Therapy ; Respiratory Insufficiency/therapy ; SARS-CoV-2
    Language English
    Publishing date 2021-06-29
    Publishing country Singapore
    Document type Letter
    ZDB-ID 2096659-3
    ISSN 1876-0821 ; 0929-6646
    ISSN (online) 1876-0821
    ISSN 0929-6646
    DOI 10.1016/j.jfma.2021.06.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1041: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Circulating tumor cells help differentiate benign ovarian lesions from cancer before surgery: A literature review and proof of concept study using flow cytometry with fluorescence imaging.

    Kuo, Yung-Chia / Chuang, Chi-Hsi / Kuo, Hsuan-Chih / Lin, Cheng-Tao / Chao, Angel / Huang, Huei-Jean / Wang, Hung-Ming / Hsieh, Jason Chia-Hsun / Chou, Hung-Hsueh

    Oncology letters

    2024  Volume 27, Issue 5, Page(s) 234

    Abstract: Current tools are insufficient for distinguishing patients with ovarian cancer from those with benign ovarian lesions before extensive surgery. The present study utilized a readily accessible platform employing a negative selection strategy, followed by ... ...

    Abstract Current tools are insufficient for distinguishing patients with ovarian cancer from those with benign ovarian lesions before extensive surgery. The present study utilized a readily accessible platform employing a negative selection strategy, followed by flow cytometry, to enumerate circulating tumor cells (CTCs) in patients with ovarian cancer. These counts were compared with those from patients with benign ovarian lesions. CTC counts at baseline, before and after anticancer therapy, and across various clinical scenarios involving ovarian lesions were assessed. A negative-selection protocol we proposed was applied to patients with suspected ovarian cancer and prospectively utilized in those subsequently confirmed to have malignancy. The protocol was implemented before anticancer therapy and at months 3, 6, 9 and 12 post-treatment. A cut-off value for CTC number at 4.75 cells/ml was established to distinguish ovarian malignancy from benign lesions, with an area under the curve of 0.900 (P<0.001). In patients with ovarian cancer, multivariate Cox regression analysis revealed that baseline CTC counts and the decline in CTCs within the first three months post-therapy were significant predictors of prolonged progression-free survival. Additionally, baseline CTC counts independently prognosticated overall survival. CTC counts obtained with the proposed platform, used in the present study, suggest that pre-operative CTC testing may be able to differentiate between malignant and benign tumors. Moreover, CTC counts may indicate oncologic outcomes in patients with ovarian cancer who have undergone cancer therapies.
    Language English
    Publishing date 2024-03-26
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2573196-8
    ISSN 1792-1082 ; 1792-1074
    ISSN (online) 1792-1082
    ISSN 1792-1074
    DOI 10.3892/ol.2024.14367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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