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  1. Article ; Online: Letter to the editor about "Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial".

    Saad, Mohamed O

    International journal of antimicrobial agents

    2021  Volume 57, Issue 1, Page(s) 106171

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Antimalarials/therapeutic use ; Antiviral Agents/therapeutic use ; Azithromycin/therapeutic use ; COVID-19/drug therapy ; COVID-19/virology ; Clinical Trials as Topic ; Drug Combinations ; Drug Repositioning ; Humans ; Hydroxychloroquine/therapeutic use ; SARS-CoV-2/pathogenicity ; Uncertainty
    Chemical Substances Anti-Bacterial Agents ; Antimalarials ; Antiviral Agents ; Drug Combinations ; Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2021-01-06
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2020.106171
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3368: Show issues Location:
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    Zs.MO 500: Show issues

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  2. Article ; Online: Presence of the neurotoxin β-N-methylamino-L-alanine in irrigation water and accumulation in cereal grains with human exposure risk.

    Mohamed, Zakaria A / Elnour, Rehab O / Alamri, Saad / Hashem, Mohamed / Campos, Alexandre / Vasconcelos, Vitor / Badawye, Hanan

    Environmental science and pollution research international

    2024  

    Abstract: The present study demonstrates the presence of the neurotoxin β-N-methylamino-L-alanine and its cyanobacterial producers in irrigation water and grains of some cereal plants from farmlands irrigated with Nile River water in Egypt. BMAA detected by LC-MS/ ... ...

    Abstract The present study demonstrates the presence of the neurotoxin β-N-methylamino-L-alanine and its cyanobacterial producers in irrigation water and grains of some cereal plants from farmlands irrigated with Nile River water in Egypt. BMAA detected by LC-MS/MS in phytoplankton samples was found at higher concentrations of free form (0.84-11.4 μg L
    Language English
    Publishing date 2024-04-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-33188-y
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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  3. Article ; Online: Retraction Note: Glycyrrhizic acid ameliorates submandibular gland oxidative stress, autophagy and vascular dysfunction in rat model of type 1 diabetes.

    Asseri, Saad Mohamed / Elsherbiny, Nehal M / El-Sherbiny, Mohamed / Sherif, Iman O / Alsamman, Alsamman M / Maysarah, Nadia M / Elsherbini, Amira M

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 327

    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Retraction of Publication
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-49826-3
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  4. Article ; Online: Retraction Note

    Saad Mohamed Asseri / Nehal M. Elsherbiny / Mohamed El-Sherbiny / Iman O. Sherif / Alsamman M. Alsamman / Nadia M. Maysarah / Amira M. Elsherbini

    Scientific Reports, Vol 14, Iss 1, Pp 1-

    Glycyrrhizic acid ameliorates submandibular gland oxidative stress, autophagy and vascular dysfunction in rat model of type 1 diabetes

    2024  Volume 1

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Extracorporeal blood purification with Oxiris

    Abdelaty, Mohamed / Mohamed, Adham / Saad, Mohamed O / Mitwally, Hassan / Alkadi, Mohamad M / Hashim, Ahmed / Al Malki, Hassan / Ali, Husain S / Mohamed, Ahmed Soliman / Mustafa, Emad / Alalawi, Abdulaziz / Elshafei, Moustafa / Othman, Muftah / Khatib, Mohamad / Ibrahim, Abdul-Salam

    The International journal of artificial organs

    2023  Volume 46, Issue 12, Page(s) 629–635

    Abstract: Introduction: Severe COVID-19 is associated with a dysregulated immune response that usually leads to cytokine release syndrome. This study aimed to compare the use of extracorporeal blood purification therapy (Oxiris: Methods: This was a national, ... ...

    Abstract Introduction: Severe COVID-19 is associated with a dysregulated immune response that usually leads to cytokine release syndrome. This study aimed to compare the use of extracorporeal blood purification therapy (Oxiris
    Methods: This was a national, multicenter, retrospective study of patients with COVID-19 admitted to the intensive care unit (ICU) between March and October 2020 who required CRRT. Patients were categorized into two groups: Oxiris
    Results: Thirty-five patients received Oxiris
    Conclusion: The number of patients alive and ventilator-free at 30-days was higher in the Oxiris
    MeSH term(s) Humans ; Continuous Renal Replacement Therapy/adverse effects ; Critical Illness ; COVID-19/therapy ; Retrospective Studies ; Interleukin-6 ; Renal Replacement Therapy ; Acute Kidney Injury/therapy
    Chemical Substances Interleukin-6
    Language English
    Publishing date 2023-11-05
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 80456-3
    ISSN 1724-6040 ; 0391-3988
    ISSN (online) 1724-6040
    ISSN 0391-3988
    DOI 10.1177/03913988231207716
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1439: Show issues Location:
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  6. Article ; Online: Anti-Xa Directed Thromboprophylaxis in Critically Ill Patients with Coronavirus Disease 2019.

    Mohamed, Adham / Shemanski, Shelby M / Saad, Mohamed O / Ploetz, Jeannette / Haines, Michelle M / Schlachter, Andrew B / Hamarshi, Majdi S

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

    2022  Volume 28, Page(s) 10760296221116350

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Anticoagulants ; COVID-19 ; Critical Illness ; Hemorrhage/chemically induced ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Retrospective Studies ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/etiology ; Venous Thromboembolism/prevention & control
    Chemical Substances Anticoagulants ; Heparin, Low-Molecular-Weight
    Language English
    Publishing date 2022-08-04
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1237357-6
    ISSN 1938-2723 ; 1076-0296
    ISSN (online) 1938-2723
    ISSN 1076-0296
    DOI 10.1177/10760296221116350
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4370: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Hyperglycemia Risk Evaluation of Hydrocortisone Intermittent Boluses vs Continuous Infusion in Septic Shock: A Retrospective Study.

    Mitwally, Hassan / Saad, Mohamed O / Mahmoud, Sara / Mohamed, Adham

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2020  Volume 25, Issue 1, Page(s) 29–33

    Abstract: ... patients.: How to cite this article: Mitwally H, Saad MO, Mahmoud S, Mohamed A. Hyperglycemia ...

    Abstract Introduction: Hydrocortisone showed to be effective in reducing the time until reversal of shock when added to standard therapy in managing septic shock. Hyperglycemia is one of the common adverse effects associated with corticosteroid treatment. However, the difference in hyperglycemia risk with different methods of hydrocortisone administration is not clear. The objective of this study was to evaluate the risk of hyperglycemia of intermittent hydrocortisone boluses vs continuous infusion in septic shock patients.
    Materials and methods: This was a retrospective observational study. Data were collected from the electronic medical records of eligible patients admitted to intensive care units. All patients admitted with septic shock who received noradrenaline and hydrocortisone were included. Only patients who exceeded 200 mg/day of hydrocortisone were excluded. The primary outcome was mean blood glucose.
    Results: A total of 108 patients (with 3,021 blood glucose readings) were included in the final analysis. Seventy-six patients received hydrocortisone as intermittent boluses (70.3%), and 32 patients (29.7%) received continuous infusion. For the primary outcome, no statistically or clinically significant difference was found in the blood glucose estimated marginal mean: 8.58 mmol/L (95% confidence interval [CI]; 8.01-9.16) in the bolus group and 8.9 mmol/L (95% CI; 7.99-9.82) in the infusion group with a mean difference of 0.32 mmol/L (95% CI; -0.77 to 1.41). For secondary outcomes, no difference was found between the two groups in mortality, length of stay, reversal of shock, or hypoglycemic events.
    Conclusion: Intermittent boluses of hydrocortisone were not associated with a higher risk of hyperglycemia than continuous infusion in septic shock patients.
    How to cite this article: Mitwally H, Saad MO, Mahmoud S, Mohamed A. Hyperglycemia Risk Evaluation of Hydrocortisone Intermittent Boluses vs Continuous Infusion in Septic Shock: A Retrospective Study. Indian J Crit Care Med 2021;25(1):29-33.
    Language English
    Publishing date 2020-07-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23501
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  8. Article ; Online: Association Between Type 1 Diabetes Mellitus and Eating Disorders: A Systematic Review and Meta-Analysis.

    Dean, Yomna E / Motawea, Karam R / Aslam, Muaaz / Pintado, Jose J Loayza / Popoola-Samuel, Helen A O / Salam, Mohamed / Dundi, Prashant Obed Reddy / Donaldy, Webster / Aledani, Esraa M / Alqiqie, Zaineh / Sultana, Nazia / Mohamed, Alaa Ramadan Hussein / Elalem, Amir / Syeda, Sidra Tahreem Hashmi / Mohamed, Mai Saad / Assal, Mazen W / Attia, Nada M / Hagar, Hanan / Abdelaziz, Heba Ahmed /
    Subedi, Anuj / Elbahaie, Areeg / Hazimeh, Yusef / Aiash, Hani

    Endocrinology, diabetes & metabolism

    2024  Volume 7, Issue 3, Page(s) e473

    Abstract: Background: Previous meta-analyses have shown mixed results regarding the association between eating disorders (EDs) and type 1 diabetes mellitus (T1DM). Our paper aimed to analyse different EDs and disordered eating behaviours that may be practiced by ... ...

    Abstract Background: Previous meta-analyses have shown mixed results regarding the association between eating disorders (EDs) and type 1 diabetes mellitus (T1DM). Our paper aimed to analyse different EDs and disordered eating behaviours that may be practiced by patients with T1DM.
    Methods: A literature search of PubMed, Scopus and Web of Science was conducted on 17 January 2023, using the key terms "T1DM," "Eating Disorders" and "Bulimia." Only observational controlled studies were included. The Revman software (version 5.4) was used for the analysis.
    Results: T1DM was associated with increased risk of ED compared with nondiabetic individuals (RR = 2.47, 95% CI = 1.84-3.32, p-value < 0.00001), especially bulimia nervosa (RR = 2.80, 95% CI = 1.18-6.65, p-value = 0.02) and binge eating (RR = 1.53, 95% CI = 1.18-1.98, p-value = 0.001). Our analysis has shown that increased risk of ED among T1DM persisted regardless of the questionnaire used to diagnose ED; DM-validated questionnaires (RR = 2.80, 95% CI = 1.91-4.12, p-value < 0.00001) and generic questionnaires (RR = 2.03, 95% CI = 1.27-3.23, p-value = 0.003). Prevalence of insulin omission/misuse was 10.3%; diabetic females demonstrated a significantly higher risk of insulin omission and insulin misuse than diabetic males.
    Conclusion: Our study establishes a significant and clear connection between EDs and T1DM, particularly bulimia and binge eating, with T1DM. Moreover, female diabetics are at higher risk of insulin misuse/omission. Early proactive screening is essential and tailored; comprehensive interventions combining diabetes and ED components are recommended for this population, with referral to a specialised psychiatrist.
    MeSH term(s) Male ; Humans ; Female ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/epidemiology ; Bulimia/complications ; Feeding and Eating Disorders/complications ; Feeding and Eating Disorders/epidemiology ; Insulin ; Insulin, Regular, Human
    Chemical Substances Insulin ; Insulin, Regular, Human
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ISSN 2398-9238
    ISSN (online) 2398-9238
    DOI 10.1002/edm2.473
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  9. Article: Impact of Early Tracheostomy on Weaning From Ventilation and Sedation in COVID-19 Pregnant and Early Postpartum Patient: Two Case Reports.

    Karic, Edin / Mitwally, Hassan / Alansari, Lolwa M / Ganaw, Adel / Saad, Mohamed O / Azhaghdani, Abdulhamid

    Cureus

    2022  Volume 14, Issue 9, Page(s) e29633

    Abstract: Pregnant women are at high risk of coronavirus disease 2019 (COVID-19) complications, including acute respiratory distress syndrome (ARDS) and the need for mechanical ventilation. There is no literature on the optimal strategy for the management of ... ...

    Abstract Pregnant women are at high risk of coronavirus disease 2019 (COVID-19) complications, including acute respiratory distress syndrome (ARDS) and the need for mechanical ventilation. There is no literature on the optimal strategy for the management of difficult-to-wean pregnant and early postpartum patients. We report two cases of pregnant women with COVID-19 pneumonia and ARDS, who required mechanical ventilation and high doses of analgesia, and sedation with neuromuscular blocking agents to facilitate ventilation and oxygenation. Both patients had a tracheostomy procedure to facilitate weaning from mechanical ventilation and sedation. Shortly after tracheostomy, sedation and analgesia, along with ventilatory support were weaned off. Both patients were discharged home. These cases propose early tracheostomy as a strategy to facilitate weaning from mechanical ventilation and sedation in pregnant and early postpartum patients.
    Language English
    Publishing date 2022-09-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.29633
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  10. Article: Spirulina platensis

    Abdel-Daim, Mohamed M / Dawood, Mahmoud A O / Elbadawy, Mohamed / Aleya, Lotfi / Alkahtani, Saad

    Animals : an open access journal from MDPI

    2020  Volume 10, Issue 3

    Abstract: Due to the numerous pharmacological impacts ... ...

    Abstract Due to the numerous pharmacological impacts of
    Language English
    Publishing date 2020-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani10030473
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