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  1. Article ; Online: Commentary in response to 'Preoperative tumor embolization prolongs time to recurrence of meningiomas: a retrospective propensity-matched analysis'.

    Gupta, Saksham / Arnaout, Omar

    Journal of neurointerventional surgery

    2022  Volume 15, Issue 8, Page(s) 831–832

    MeSH term(s) Humans ; Meningioma/surgery ; Retrospective Studies ; Meningeal Neoplasms/surgery ; Embolization, Therapeutic ; Preoperative Care
    Language English
    Publishing date 2022-09-09
    Publishing country England
    Document type Letter
    ZDB-ID 2514982-9
    ISSN 1759-8486 ; 1759-8478
    ISSN (online) 1759-8486
    ISSN 1759-8478
    DOI 10.1136/jnis-2022-019498
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6845: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Postoperative Pathway Allows Elective Craniotomy Patients to Bypass Intensive Care Unit Safely: Commentary on Recent Article in Journal of Neurosurgery.

    Hoffman, Samantha E / Gupta, Saksham / Arnaout, Omar

    World neurosurgery

    2023  Volume 173, Page(s) 276–277

    MeSH term(s) Humans ; Neurosurgery ; Neurosurgical Procedures ; Intensive Care Units ; Craniotomy ; Elective Surgical Procedures ; Postoperative Complications
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Letter
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.02.126
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    Zs.A 1159: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Evaluation of the safety, accuracy, and helpfulness of the GPT-4.0 Large Language Model in neurosurgery.

    Huang, Kevin T / Mehta, Neel H / Gupta, Saksham / See, Alfred P / Arnaout, Omar

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2024  Volume 123, Page(s) 151–156

    Abstract: Background: Although prior work demonstrated the surprising accuracy of Large Language Models (LLMs) on neurosurgery board-style questions, their use in day-to-day clinical situations warrants further investigation. This study assessed GPT-4.0's ... ...

    Abstract Background: Although prior work demonstrated the surprising accuracy of Large Language Models (LLMs) on neurosurgery board-style questions, their use in day-to-day clinical situations warrants further investigation. This study assessed GPT-4.0's responses to common clinical questions across various subspecialties of neurosurgery.
    Methods: A panel of attending neurosurgeons formulated 35 general neurosurgical questions spanning neuro-oncology, spine, vascular, functional, pediatrics, and trauma. All questions were input into GPT-4.0 with a prespecified, standard prompt. Responses were evaluated by two attending neurosurgeons, each on a standardized scale for accuracy, safety, and helpfulness. Citations were indexed and evaluated against identifiable database references.
    Results: GPT-4.0 responses were consistent with current medical guidelines and accounted for recent advances in the field 92.8 % and 78.6 % of the time respectively. Neurosurgeons reported GPT-4.0 responses providing unrealistic information or potentially risky information 14.3 % and 7.1 % of the time respectively. Assessed on 5-point scales, responses suggested that GPT-4.0 was clinically useful (4.0 ± 0.6), relevant (4.7 ± 0.3), and coherent (4.9 ± 0.2). The depth of clinical responses varied (3.7 ± 0.6), and "red flag" symptoms were missed 7.1 % of the time. Moreover, GPT-4.0 cited 86 references (2.46 citations per answer), of which only 50 % were deemed valid, and 77.1 % of responses contained at least one inappropriate citation.
    Conclusion: Current general LLM technology can offer generally accurate, safe, and helpful neurosurgical information, but may not fully evaluate medical literature or recent field advances. Citation generation and usage remains unreliable. As this technology becomes more ubiquitous, clinicians will need to exercise caution when dealing with it in practice.
    MeSH term(s) Humans ; Neurosurgery/methods ; Neurosurgery/standards ; Neurosurgeons/standards ; Neurosurgical Procedures/methods ; Neurosurgical Procedures/standards ; Language
    Language English
    Publishing date 2024-04-04
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2024.03.021
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    Zs.A 3999: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article: Emergent Coronary Thrombectomy for Acute Myocardial Infarction Immediately Following Craniotomy with Tumor Resection.

    Ginder, Curtis R / Suero-Abreu, Giselle A / Ghumman, Saad S / Bergmark, Brian A / Arnaout, Omar / Giugliano, Robert P

    Cardiology and therapy

    2024  

    Abstract: The management of perioperative acute myocardial infarction (AMI) following oncologic neurosurgery requires balancing competing risks of myocardial ischemia and postoperative bleeding. There are limited human data to establish the safest timing of ... ...

    Abstract The management of perioperative acute myocardial infarction (AMI) following oncologic neurosurgery requires balancing competing risks of myocardial ischemia and postoperative bleeding. There are limited human data to establish the safest timing of antiplatelet or anticoagulation therapy following neurosurgical procedures. For patients with malignancy experiencing AMI in the acute postoperative period, staged percutaneous coronary intervention (PCI) with upfront coronary aspiration thrombectomy followed by delayed completion PCI may offer an opportunity for myocardial salvage while minimizing postoperative bleeding risks. CYP2C19 genotyping and platelet aggregation studies can help confirm adequate platelet inhibition once antiplatelet therapy is resumed.
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2700626-8
    ISSN 2193-6544 ; 2193-8261
    ISSN (online) 2193-6544
    ISSN 2193-8261
    DOI 10.1007/s40119-024-00356-7
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  5. Article ; Online: Endoscopic endonasal transclival approach for a ventral brainstem epidermoid cyst: illustrative case.

    Hauser, Blake M / Gupta, Saksham / Athni, Tejas S / Segar, David J / Uppaluri, Ravindra / Arnaout, Omar

    Journal of neurosurgery. Case lessons

    2023  Volume 5, Issue 13

    Abstract: Background: Intracranial epidermoid cysts are benign, slow-growing malformations that most commonly arise at the skull base. Maximizing resection of the cyst contents and the capsule reduces long-term recurrence but can be made difficult by cyst wall ... ...

    Abstract Background: Intracranial epidermoid cysts are benign, slow-growing malformations that most commonly arise at the skull base. Maximizing resection of the cyst contents and the capsule reduces long-term recurrence but can be made difficult by cyst wall adherence to critical neurovascular structures. Expanded endonasal approaches (EEAs) offer an alternative to traditional open transcranial approaches for accessible epidermoid cysts. In this case report, the authors demonstrate a transclival EEA for a large, ventral brainstem epidermoid cyst.
    Observations: A 41-year-old woman who presented with progressive headaches, diplopia, malaise, and fatigue was found to have a 4.7-cm midline, ventral brainstem epidermoid cyst. She underwent an expanded endonasal transclival approach that exposed the brainstem from the level of the dorsum sella to the tip of the basion. A near-total resection was completed with removal of all cyst contents and most of the capsular wall. Reconstruction was completed with Duragen, an autologous fat graft, and a nasoseptal flap. Postoperatively, she had a partial left cranial nerve VI palsy that remained stable 8 weeks after surgery.
    Lessons: The expanded endoscopic transclival approach can facilitate effective resection of midline, ventral epidermoid cysts.
    Language English
    Publishing date 2023-03-27
    Publishing country United States
    Document type Journal Article
    ISSN 2694-1902
    ISSN (online) 2694-1902
    DOI 10.3171/CASE22538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Intracranial stimulation for brain cancer-The case for implantable, intracranial tumor treating fields.

    Segar, David J / Bernstock, Joshua D / Rampersad, Sumientra / Bi, Wenya Linda / Arnaout, Omar / Friedman, Gregory K / Chiocca, E Antonio

    Neuro-oncology advances

    2023  Volume 5, Issue 1, Page(s) vdad100

    Language English
    Publishing date 2023-08-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3009682-0
    ISSN 2632-2498 ; 2632-2498
    ISSN (online) 2632-2498
    ISSN 2632-2498
    DOI 10.1093/noajnl/vdad100
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  7. Article ; Online: Author Correction: Modeling of intracranial tumor treating fields for the treatment of complex high-grade gliomas.

    Segar, David J / Bernstock, Joshua D / Arnaout, Omar / Bi, Wenya Linda / Friedman, Gregory K / Langer, Robert / Traverso, Giovanni / Rampersad, Sumientra M

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 3955

    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-30970-9
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  8. Article ; Online: Unexpected Resolution of a Symptomatic Tarlov Cyst Following Hysterectomy.

    Lak, Asad M / Zaidi, Hasan A / Arnaout, Omar

    JAMA neurology

    2020  Volume 77, Issue 8, Page(s) 1032–1033

    MeSH term(s) Female ; Humans ; Hysterectomy ; Leiomyoma/diagnosis ; Leiomyoma/surgery ; Middle Aged ; Sacrum ; Tarlov Cysts/diagnosis ; Tarlov Cysts/therapy ; Treatment Outcome ; Uterine Neoplasms/diagnosis ; Uterine Neoplasms/surgery
    Language English
    Publishing date 2020-05-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2702023-X
    ISSN 2168-6157 ; 2168-6149
    ISSN (online) 2168-6157
    ISSN 2168-6149
    DOI 10.1001/jamaneurol.2020.1078
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    Ui II Zs.191: Show issues Location:
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  9. Article ; Conference proceedings: Extent of Resection and Preoperative Hemorrhage Predict Recurrence for Intraventricular Meningiomas

    Duvall, Julia B. / Gupta, Saksham / Chua, Melissa M. / Emani, Siva / Arnaout, Omar

    Journal of Neurological Surgery Part B: Skull Base

    2023  Volume 84, Issue S 01

    Event/congress 32nd Annual Meeting North American Skull Base Society, JW Marriott Tampa Water Street, Tampa, Florida, United States, 2023-02-17
    Language English
    Publishing date 2023-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0043-1762028
    Database Thieme publisher's database

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    Zs.A 3425: Show issues Location:
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  10. Article ; Online: Letter: Adaptation Under Fire: Two Harvard Neurosurgical Services During the COVID-19 Pandemic.

    Arnaout, Omar / Patel, Aman / Carter, Bob / Chiocca, E Antonio

    Neurosurgery

    2020  Volume 87, Issue 2, Page(s) E173–E177

    Keywords covid19
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyaa146
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    Zs.MO 539: Show issues

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