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  1. Article ; Online: Prednisone and Live Birth Rate in Patients With Recurrent Implantation Failure.

    Cavalcante, Marcelo Borges / Barini, Ricardo

    JAMA

    2023  Volume 330, Issue 10, Page(s) 970–971

    MeSH term(s) Humans ; Birth Rate ; Prednisone/pharmacology ; Prednisone/therapeutic use ; Female ; Pregnancy ; Infant, Newborn ; Pregnancy Complications/drug therapy ; Recurrence ; Embryo Implantation/drug effects ; Reproductive Control Agents/pharmacology ; Reproductive Control Agents/therapeutic use ; Pregnancy Outcome
    Chemical Substances Prednisone (VB0R961HZT) ; Reproductive Control Agents
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.12628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.88: Show issues Location:
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  2. Article ; Online: Recurrent pregnancy loss and hereditary thrombophilias - is it time to review the guidelines?

    Cavalcante, Marcelo Borges / Barini, Ricardo

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

    2022  Volume 42, Issue 6, Page(s) 2545–2546

    MeSH term(s) Abortion, Habitual/genetics ; Female ; Humans ; Pregnancy ; Pregnancy Complications, Hematologic/therapy ; Thrombophilia
    Language English
    Publishing date 2022-05-25
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604639-3
    ISSN 1364-6893 ; 0144-3615
    ISSN (online) 1364-6893
    ISSN 0144-3615
    DOI 10.1080/01443615.2022.2054690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Immunotherapies to optimize pregnancy outcomes in subfertile women.

    Cavalcante, Marcelo Borges / Sarno, Manoel / Barini, Ricardo

    Human reproduction update

    2022  Volume 28, Issue 4, Page(s) 601–602

    MeSH term(s) Female ; Humans ; Immunotherapy ; Infertility, Female/therapy ; Pregnancy ; Pregnancy Outcome ; Pregnancy Rate
    Language English
    Publishing date 2022-06-15
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1286738-x
    ISSN 1460-2369 ; 1355-4786
    ISSN (online) 1460-2369
    ISSN 1355-4786
    DOI 10.1093/humupd/dmac017
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  4. Article ; Online: ESHRE guideline update 2022: New perspectives in the management of couples with recurrent pregnancy loss.

    Cavalcante, Marcelo Borges / Sampaio, Olga Goiana Martins / Câmara, Fernanda Eunice Araújo / Barini, Ricardo

    American journal of reproductive immunology (New York, N.Y. : 1989)

    2023  Volume 90, Issue 2, Page(s) e13739

    MeSH term(s) Female ; Humans ; Pregnancy ; Abortion, Habitual/therapy ; Practice Guidelines as Topic
    Language English
    Publishing date 2023-07-26
    Publishing country Denmark
    Document type Letter ; Comment
    ZDB-ID 604542-x
    ISSN 1600-0897 ; 0271-7352 ; 8755-8920 ; 1046-7408
    ISSN (online) 1600-0897
    ISSN 0271-7352 ; 8755-8920 ; 1046-7408
    DOI 10.1111/aji.13739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1653: Show issues Location:
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  5. Article ; Online: Endometrial scratching for embryo implantation failure-uterine immune biomarkers as a selection criterion.

    Cavalcante, Marcelo Borges / Barini, Ricardo / Kwak-Kim, Joanne

    Human reproduction (Oxford, England)

    2021  Volume 36, Issue 5, Page(s) 1446–1447

    MeSH term(s) Biomarkers ; Embryo Implantation ; Endometrium ; Female ; Humans ; Sperm Injections, Intracytoplasmic
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-03-08
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 632776-x
    ISSN 1460-2350 ; 0268-1161 ; 1477-741X
    ISSN (online) 1460-2350
    ISSN 0268-1161 ; 1477-741X
    DOI 10.1093/humrep/deab061
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    Zs.B 2892: Show issues Location:
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  6. Article ; Online: Lymphocyte immunotherapy in recurrent miscarriage and recurrent implantation failure.

    Cavalcante, Marcelo Borges / Sarno, Manoel / Barini, Ricardo

    American journal of reproductive immunology (New York, N.Y. : 1989)

    2021  Volume 85, Issue 4, Page(s) e13408

    Abstract: Problem: Lymphocyte immunotherapy (LIT) emerged in the early 1980s as a new therapeutic proposal for couples with a history of recurrent miscarriages (RM). However, in the early 2000s, the effectiveness of LIT was questioned. Recently, meta-analyses ... ...

    Abstract Problem: Lymphocyte immunotherapy (LIT) emerged in the early 1980s as a new therapeutic proposal for couples with a history of recurrent miscarriages (RM). However, in the early 2000s, the effectiveness of LIT was questioned. Recently, meta-analyses have observed the effectiveness and safety of LIT in treating couples with RM. Some studies evaluated the use of LIT in recurrent implantation failure (RIF) in in vitro fertilization cycles.
    Methods: This systematic and narrative review evaluated the data available in the literature regarding the efficacy and safety of the use of LIT. Searches in PubMed/Medline, Embase, and Cochrane Library databases were conducted, using the following keywords: "recurrent miscarriage," "lymphocyte immunotherapy," and "recurrent implantation failure".
    Results: This review describes the historical aspects of LIT and discusses its protocols, mechanisms of action, side effects, complications, and current evidence of the effectiveness in cases of reproductive failure. It also discusses the use of LIT during the COVID-19 pandemic and new immunological therapies.
    Conclusion: In the vast majority of studies, the use of LIT for RM couples has shown an improvement in pregnancy outcomes. The most of the current studies that support the evidence are quasi-experimental, with few randomized, double-blind studies (Level of evidence III). However, the current evidence are not convincing for the use of LIT in RIF patients.
    MeSH term(s) Abortion, Habitual/therapy ; COVID-19 ; Female ; Humans ; Immunotherapy ; Lymphocyte Transfusion ; Lymphocytes ; Pandemics ; Pregnancy ; SARS-CoV-2
    Language English
    Publishing date 2021-03-10
    Publishing country Denmark
    Document type Journal Article ; Systematic Review
    ZDB-ID 604542-x
    ISSN 1600-0897 ; 0271-7352 ; 8755-8920 ; 1046-7408
    ISSN (online) 1600-0897
    ISSN 0271-7352 ; 8755-8920 ; 1046-7408
    DOI 10.1111/aji.13408
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    Zs.A 1653: Show issues Location:
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  7. Article ; Online: Clinical efficacy of triclosan-containing toothpaste in peri-implant health: A systematic review and meta-analysis of randomized clinical trials.

    Costa, Raphael Cavalcante / Borges, Guilherme Almeida / Dini, Caroline / Bertolini, Martinna / Souza, Joāo Gabriel S / Mesquita, Marcelo Ferraz / Barão, Valentim Adelino Ricardo

    The Journal of prosthetic dentistry

    2023  

    Abstract: Statement of problem: Recent evidence suggests that toothpaste containing 0.3% triclosan (TCS) is more effective than regular toothpaste in improving clinical periodontal conditions. However, a consensus on whether TCS favors a healthy peri-implant ... ...

    Abstract Statement of problem: Recent evidence suggests that toothpaste containing 0.3% triclosan (TCS) is more effective than regular toothpaste in improving clinical periodontal conditions. However, a consensus on whether TCS favors a healthy peri-implant environment is limited.
    Purpose: The purpose of this systematic review and meta-analysis of randomized clinical trials was to determine the effects of TCS-containing toothpaste on dental implant health based on clinical, immunological, and microbiological parameters, as well as on reported adverse events.
    Material and methods: Clinical studies comparing peri-implant conditions in participants by using TCS toothpaste versus conventional fluoride toothpaste (control) were extracted from 9 databases. The studies were assessed with the Cochrane risk-of-bias tool for randomized clinical trials (RoB 2). Datasets for bleeding on probing (BOP), probing depth (PD), clinical attachment level (CAL), gingival index (GI), plaque index (PI), osteo-immunoinflammatory mediators, and bacterial load were plotted, and the standard mean difference (SMD) quantitative analysis was applied by using the Rev Man 5.3 software program. Adverse effects reported by the studies were also tabulated. The certainty of evidence was assessed by using the grading of recommendations assessment, development, and evaluation approach.
    Results: Six studies were included in the meta-analyses. BOP was higher in the control group than in the TCS toothpaste group at 3 months (SMD -0.59 [-1.11, -.07] P=.002, I
    Conclusions: Most studies were short-term (3 and 6 months) analyses, and the results found that, although TCS-containing toothpaste had positive osteo-immunoinflammatory and microbiologic results, clinical parameters, including CAL, GI, and PI, were not influenced.
    Language English
    Publishing date 2023-09-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 218157-5
    ISSN 1097-6841 ; 0022-3913
    ISSN (online) 1097-6841
    ISSN 0022-3913
    DOI 10.1016/j.prosdent.2023.08.006
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    Ul III Zs.145: Show issues Location:
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  8. Article ; Online: Screening for coronavirus disease 2019 in pregnant women admitted for delivery: an observational study.

    Cavalcante, Ana Nery Melo / Almeida, Rosa Lívia Freitas de / Oliveira, Denise Nunes / Lima, Danielle Malta / Cavalcante, Candice Torres de Melo Bezerra / Tavares, Lohanna Valeska de Sousa / Almeida, Renata Parente / Machado, Rosângela Pinheiro Gonçalves / Araujo Júnior, Edward / Cavalcante, Marcelo Borges

    Revista da Associacao Medica Brasileira (1992)

    2023  Volume 69, Issue 7, Page(s) e20230084

    Abstract: Objective: The aim of this study was to examine the impact of symptom-based screening on the prevalence and outcomes of neonatal coronavirus disease 2019 in pregnant women admitted for delivery.: Methods: A retrospective observational study was ... ...

    Abstract Objective: The aim of this study was to examine the impact of symptom-based screening on the prevalence and outcomes of neonatal coronavirus disease 2019 in pregnant women admitted for delivery.
    Methods: A retrospective observational study was conducted from June to August 2020 at Gonzaga Mota of Messejana Hospital, Fortaleza, CE, Brazil. All pregnant women were screened for coronavirus disease 2019 based on symptoms. Reverse transcription-polymerase chain reaction or immunology assays for severe acute respiratory syndrome coronavirus 2 were performed when a patient reported a symptom. All newborns of symptomatic patients were submitted for Reverse transcription-polymerase chain reaction. Newborns were divided into groups according to the Reverse transcription-polymerase chain reaction results to identify the relationship between maternal symptoms and neonatal coronavirus disease 2019.
    Results: A total of 55 (55/1,026, 5.4%) and 50 (50/1,026, 4.8%) pregnant women reported symptoms and had a positive confirmatory test, respectively. The most common symptom of coronavirus disease 2019 among the pregnant women with positive confirmatory test was cough (n=23, 46%). Seven newborns (7/50, 14%) of symptomatic mothers had positive Reverse transcription-polymerase chain reaction. Upon birth, no newborn had serious complications.
    Conclusion: Universal screening of pregnant women admitted for delivery can reduce the perinatal transmission of coronavirus disease 2019. Symptom-based screening can be an alternative for regions with a low prevalence of the disease where a better allocation of financial resources is necessary.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; COVID-19/diagnosis ; COVID-19/epidemiology ; Pregnant Women ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/epidemiology ; Infectious Disease Transmission, Vertical ; SARS-CoV-2 ; Pregnancy Outcome
    Language English
    Publishing date 2023-07-17
    Publishing country Brazil
    Document type Observational Study ; Journal Article
    ZDB-ID 731969-1
    ISSN 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X
    ISSN (online) 1806-9282
    ISSN 0104-4230 ; 0004-5241 ; 0102-843X
    DOI 10.1590/1806-9282.20230084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 654: Show issues Location:
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  9. Article ; Online: Obesity and recurrent miscarriage: The interconnections between adipose tissue and the immune system.

    Gonçalves, Cristiano César Rodrigues Augusto / Feitosa, Beatriz Memória / Cavalcante, Beatriz Vieira / Lima, André Lucas Grangeiro de Sá Barreto / de Souza, Caroline Martins / Joventino, Larissa Brandão / Cavalcante, Marcelo Borges

    American journal of reproductive immunology (New York, N.Y. : 1989)

    2023  Volume 90, Issue 3, Page(s) e13757

    Abstract: Currently, obesity is considered a global public health problem. It is the main risk factor for noncommunicable diseases and reproductive complications, such as recurrent miscarriage (RM). RM affects approximately 1% of couples of reproductive age, and ... ...

    Abstract Currently, obesity is considered a global public health problem. It is the main risk factor for noncommunicable diseases and reproductive complications, such as recurrent miscarriage (RM). RM affects approximately 1% of couples of reproductive age, and recent studies suggest that its prevalence is increasing. Immunological abnormalities may be responsible for a significant number of cases of unexplained RM. Obesity is recognized as a chronic low-grade inflammatory condition. The accumulation of fat in obese adipose tissue promotes changes in the local and systemic immune response. Adipokines, exosomes, micro-RNAs, lipids, and other factors released or secreted by adipose tissue are responsible for the interconnection between obesity and the immune system. Obesity-induced dysregulation of the innate and acquired immune response is also involved in the immunopathology of pregnancy loss in patients with unexplained RM. Therefore, understanding the communication pathways between maternal adipose tissue and the immune response in women living with obesity and RM is an important objective. Thus, diagnostic tools and new immunomodulatory therapies may be proposed for the management of patients with concurrent obesity and RM.
    MeSH term(s) Pregnancy ; Humans ; Female ; Abortion, Habitual/epidemiology ; Obesity/epidemiology ; MicroRNAs ; Immune System ; Adipose Tissue
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2023-08-29
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 604542-x
    ISSN 1600-0897 ; 0271-7352 ; 8755-8920 ; 1046-7408
    ISSN (online) 1600-0897
    ISSN 0271-7352 ; 8755-8920 ; 1046-7408
    DOI 10.1111/aji.13757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1653: Show issues Location:
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  10. Article: Coagulation Biomarkers in Women with Recurrent Miscarriage and Polycystic Ovarian Syndrome: Systematic Review and Meta-Analysis.

    Cavalcante, Marcelo Borges / Sarno, Manoel / Cavalcante, Candice Torres de Melo Bezerra / Araujo Júnior, Edward / Barini, Ricardo

    Geburtshilfe und Frauenheilkunde

    2019  Volume 79, Issue 7, Page(s) 697–704

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2019-07-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80111-2
    ISSN 1438-8804 ; 0016-5751 ; 1615-3359
    ISSN (online) 1438-8804
    ISSN 0016-5751 ; 1615-3359
    DOI 10.1055/a-0884-3212
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