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  1. Article ; Online: Admission in Internal Medicine: The Italian issue.

    Mazzone, Antonino / Montano, Nicola

    European journal of internal medicine

    2024  

    Language English
    Publishing date 2024-03-09
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.02.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: New Coronary Heart Disease Risk Factors: The Dark Side of the Moon.

    Mazzone, Antonino / Mumoli, Nicola

    The American journal of medicine

    2023  Volume 136, Issue 9, Page(s) e188–e189

    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Letter
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2023.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Antibiotic shortages in Europe: Another question of prices?

    Garattini, L / Finazzi, B / Mazzone, A

    European journal of internal medicine

    2024  

    Language English
    Publishing date 2024-03-16
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.03.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Atrial tachycardia ablation through the sub-pulmonary ventricle in a patient with multiple malformations associated with congenitally corrected transposition of the great arteries and double-sided slow-pathway.

    Preda, Alberto / Testoni, Alessio / Baroni, Matteo / Mazzone, Patrizio / Gigli, Lorenzo

    Clinical case reports

    2024  Volume 12, Issue 4, Page(s) e8745

    Abstract: A 46-year-old woman with congenitally corrected transposition of the great arteries (ccTGA) associated with dextrocardia, situs viscerus inversus, and left superior vena cava persistence presented with an incessant supraventricular tachycardia. ... ...

    Abstract A 46-year-old woman with congenitally corrected transposition of the great arteries (ccTGA) associated with dextrocardia, situs viscerus inversus, and left superior vena cava persistence presented with an incessant supraventricular tachycardia. Electrophysiological study was not conclusive in differential diagnosis of atrial tachycardia versus atypical atrioventricular (AV) nodal reentrant tachycardia, also due to the unconventional anatomy of the coronary sinus. By a comprehensive mapping of cardiac chambers, a double side slow-pathway was localized in both atrial chambers and subsequently ablated by radiofrequency delivery without tachycardia changes. Aortic root and cusps were devoid of electrical activity. The muscular part of the sub-pulmonary ventricle at the level of interatrial septum showed an earliest activation signal of -90 ms and ablation of this site was effective in abolish the tachycardia. This is the first case to report technical concerns of septal atrial tachycardia ablation in ccTGA associated with multiple anatomical malformations. Moreover, some peculiarities have been reported for the first time including the presence of double-side AV nodal slow-pathway and atypical localization of the tachycardia origin into the muscular part of the sub-pulmonary ventricle instead of posterior pulmonary cusp.
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.8745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Left atrial appendage occlusion: from guidelines to real life, where is the gap?

    Mazzone, Patrizio / Radinovic, Andrea

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2022  Volume 23, Issue 3, Page(s) 183–184

    MeSH term(s) Anticoagulants ; Atrial Appendage/diagnostic imaging ; Atrial Appendage/physiopathology ; Atrial Appendage/surgery ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/therapy ; Humans
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A collaborative synthetase.

    Mazzone, Massimiliano / Castegna, Alessandra

    Nature chemical biology

    2022  Volume 19, Issue 3, Page(s) 255–256

    MeSH term(s) Ligases
    Chemical Substances Ligases (EC 6.-)
    Language English
    Publishing date 2022-10-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2202962-X
    ISSN 1552-4469 ; 1552-4450
    ISSN (online) 1552-4469
    ISSN 1552-4450
    DOI 10.1038/s41589-022-01171-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Thermal comfort and cooling strategies in the Brazilian Amazon. An assessment of the concept of fuel poverty in tropical climates

    Mazzone, Antonella

    Energy policy. 2020 Apr., v. 139

    2020  

    Abstract: Fuel poverty has increasingly been associated with thermal discomfort, health related issues and winter deaths in the Global North because it can force families to choose between food and a warmer environment. Juxtaposing the concept of fuel poverty in ... ...

    Abstract Fuel poverty has increasingly been associated with thermal discomfort, health related issues and winter deaths in the Global North because it can force families to choose between food and a warmer environment. Juxtaposing the concept of fuel poverty in rural tropical areas of the Global South, it is likely that a similar pattern between fuel poverty and heat related illnesses can be found. A recent study shows that between 1.8 and 4.1 billion people, especially in India, Southeast Asia and Sub-Saharan Africa will need indoor cooling to avoid heat related health issues. This paper aims to address a blind spot in the literature on the links between fuel poverty, thermal comfort and cooling strategies in the Brazilian Amazon.This study draws from current definitions and indicators of fuel poverty in the Global North and juxtaposes it in the context of tropical areas to understand how fuel poverty affects human health, livelihood strategies and social justice in rural communities that live in hot climates. To do so, this paper uses qualitative methods and a conceptual framework to guide the analysis. I call the intersection between vernacular architecture and sustainable cooling practices ‘energy relief’.
    Keywords cooling ; energy poverty ; heat ; human health ; livelihood ; people ; qualitative analysis ; rural communities ; social justice ; tropics ; winter ; Amazonia ; Brazil ; India ; South East Asia ; Sub-Saharan Africa
    Language English
    Dates of publication 2020-04
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0301-4215
    DOI 10.1016/j.enpol.2020.111256
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: From monocyte-derived macrophages to resident macrophages-how metabolism leads their way in cancer.

    Ammarah, Ummi / Pereira-Nunes, Andreia / Delfini, Marcello / Mazzone, Massimiliano

    Molecular oncology

    2024  

    Abstract: Macrophages are innate immune cells that play key roles during both homeostasis and disease. Depending on the microenvironmental cues sensed in different tissues, macrophages are known to acquire specific phenotypes and exhibit unique features that, ... ...

    Abstract Macrophages are innate immune cells that play key roles during both homeostasis and disease. Depending on the microenvironmental cues sensed in different tissues, macrophages are known to acquire specific phenotypes and exhibit unique features that, ultimately, orchestrate tissue homeostasis, defense, and repair. Within the tumor microenvironment, macrophages are referred to as tumor-associated macrophages (TAMs) and constitute a heterogeneous population. Like their tissue resident counterpart, TAMs are plastic and can switch function and phenotype according to the niche-derived stimuli sensed. While changes in TAM phenotype are known to be accompanied by adaptive alterations in their cell metabolism, it is reported that metabolic reprogramming of macrophages can dictate their activation state and function. In line with these observations, recent research efforts have been focused on defining the metabolic traits of TAM subsets in different tumor malignancies and understanding their role in cancer progression and metastasis formation. This knowledge will pave the way to novel therapeutic strategies tailored to cancer subtype-specific metabolic landscapes. This review outlines the metabolic characteristics of distinct TAM subsets and their implications in tumorigenesis across multiple cancer types.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2415106-3
    ISSN 1878-0261 ; 1574-7891
    ISSN (online) 1878-0261
    ISSN 1574-7891
    DOI 10.1002/1878-0261.13618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Acute Myocardial Infarction in the Era of COVID-19: A Challenge in a Challenge.

    Mazzone, Annamaria / Berti, Sergio / Vassalle, Cristina

    Journal of clinical medicine

    2023  Volume 12, Issue 18

    Abstract: From the very beginning, the coronavirus pandemic (COVID-19) has tested the healthcare systems, having unpredictable and extreme adverse impacts on acute care clinical settings [ ... ]. ...

    Abstract From the very beginning, the coronavirus pandemic (COVID-19) has tested the healthcare systems, having unpredictable and extreme adverse impacts on acute care clinical settings [...].
    Language English
    Publishing date 2023-09-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12185779
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Role of Toll-like Receptors (TLRs) Mediated Inflammation in Pancreatic Cancer Pathophysiology.

    Orlacchio, Arturo / Mazzone, Pellegrino

    International journal of molecular sciences

    2021  Volume 22, Issue 23

    Abstract: Pancreatic cancer (PC) is one of the most lethal forms of cancer, characterized by its aggressiveness and metastatic potential. Despite significant improvements in PC treatment and management, the complexity of the molecular pathways underlying its ... ...

    Abstract Pancreatic cancer (PC) is one of the most lethal forms of cancer, characterized by its aggressiveness and metastatic potential. Despite significant improvements in PC treatment and management, the complexity of the molecular pathways underlying its development has severely limited the available therapeutic opportunities. Toll-like receptors (TLRs) play a pivotal role in inflammation and immune response, as they are involved in pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs). Activation of TLRs initiates a signaling cascade, which in turn, leads to the transcription of several genes involved in inflammation and anti-microbial defense. TLRs are also deregulated in several cancers and can be used as prognostic markers and potential targets for cancer-targeted therapy. In this review we discuss the current knowledge about the role of TLRs in PC progression, focusing on the available TLRs-targeting compounds and their possible use in PC therapy.
    MeSH term(s) Animals ; Humans ; Inflammation/complications ; Inflammation/metabolism ; Pancreatic Neoplasms/etiology ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Signal Transduction ; Toll-Like Receptors/metabolism
    Chemical Substances Toll-Like Receptors
    Language English
    Publishing date 2021-11-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms222312743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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