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Article ; Online: Level of Evidence during the COVID-19 Pandemic: Making the Case for Case Series and Case Reports.

Ikuta, I

AJNR. American journal of neuroradiology

2020 Volume 41, Issue 9, Page(s) 1646

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Hypoxia ; Leukoencephalopathies ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-02
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	603808-6
ISSN	1936-959X ; 0195-6108
ISSN (online)	1936-959X
ISSN	0195-6108
DOI	10.3174/ajnr.A6676
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Level of Evidence during the COVID-19 Pandemic: Making the Case for Case Series and Case Reports

Ikuta, I

AJNR Am J Neuroradiol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #631170
Database	COVID19

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Article ; Online: Understanding Bias in Artificial Intelligence: A Practice Perspective.

Davis, Melissa A / Wu, Ona / Ikuta, Ichiro / Jordan, John E / Johnson, Michele H / Quigley, Edward

AJNR. American journal of neuroradiology

2024 Volume 45, Issue 4, Page(s) 371–373

Abstract: In the fall of 2021, several experts in this space delivered a Webinar hosted by the American Society of Neuroradiology (ASNR) Diversity and Inclusion Committee, focused on expanding the understanding of bias in artificial intelligence, with a health ... ...

Abstract	In the fall of 2021, several experts in this space delivered a Webinar hosted by the American Society of Neuroradiology (ASNR) Diversity and Inclusion Committee, focused on expanding the understanding of bias in artificial intelligence, with a health equity lens, and provided key concepts for neuroradiologists to approach the evaluation of these tools. In this perspective, we distill key parts of this discussion, including understanding why this topic is important to neuroradiologists and lending insight on how neuroradiologists can develop a framework to assess health equity-related bias in artificial intelligence tools. In addition, we provide examples of clinical workflow implementation of these tools so that we can begin to see how artificial intelligence tools will impact discourse on equitable radiologic care. As continuous learners, we must be engaged in new and rapidly evolving technologies that emerge in our field. The Diversity and Inclusion Committee of the ASNR has addressed this subject matter through its programming content revolving around health equity in neuroradiologic advances.
MeSH term(s)	Humans ; Artificial Intelligence ; Radiologists ; Radiology ; Workflow
Language	English
Publishing date	2024-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	603808-6
ISSN	1936-959X ; 0195-6108
ISSN (online)	1936-959X
ISSN	0195-6108
DOI	10.3174/ajnr.A8070
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Article ; Online: Visualizing Formation and Dynamics of a Three-Dimensional Sponge-like Network of a Coacervate in Real Time.

Kubota, Ryou / Hiroi, Taro / Ikuta, Yuriki / Liu, Yuchong / Hamachi, Itaru

Journal of the American Chemical Society

2023 Volume 145, Issue 33, Page(s) 18316–18328

Abstract: Coacervates, which are formed by liquid-liquid phase separation, have been extensively explored as models for synthetic cells and membraneless organelles, so their in-depth structural analysis is crucial. However, both the inner structure dynamics and ... ...

Abstract	Coacervates, which are formed by liquid-liquid phase separation, have been extensively explored as models for synthetic cells and membraneless organelles, so their in-depth structural analysis is crucial. However, both the inner structure dynamics and formation mechanism of coacervates remain elusive. Herein, we demonstrate real-time confocal observation of a three-dimensional sponge-like network in a dipeptide-based coacervate.
Language	English
Publishing date	2023-08-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	3155-0
ISSN	1520-5126 ; 0002-7863
ISSN (online)	1520-5126
ISSN	0002-7863
DOI	10.1021/jacs.3c03793
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Article ; Online: [Efforts to improve workplaces considering for older workers: A questionnaire survey focusing on company size in Wakayama Prefecture, Japan].

Morioka, Ikuharu / Takeshita, Tatsuya / Miyashita, Kazuhisa / Fujiyoshi, Akira / Ikuta, Zentaro

Sangyo eiseigaku zasshi = Journal of occupational health

2023 Volume 65, Issue 6, Page(s) 355–365

Abstract: Objectives: The "Guidelines for Ensuring the Safety and Health of Older Workers (hereafter referred to as "Guidelines")," formulated in 2021, require employers to implement measures that proactively prevent occupational accidents among older workers. ... ...

Abstract	Objectives: The "Guidelines for Ensuring the Safety and Health of Older Workers (hereafter referred to as "Guidelines")," formulated in 2021, require employers to implement measures that proactively prevent occupational accidents among older workers. This study aimed to clarify the status of awareness of the Guidelines and workplace improvement efforts with consideration of older workers, focusing on company size. Methods: Overall, 780 businesses in Wakayama Prefecture, Japan, were randomly selected from a Wakayama Occupational Health Support Center workplace list. Anonymous self-administered questionnaires were distributed by mail. The questionnaires comprised questions about the workplace, status of awareness of the Guidelines, comprehensive management of safety and health, considerations for working conditions, workers, workload reduction, work posture, work environment, and safety and health. Results: One hundred and seventy-one businesses (effective response rate: 21.9%) provided questionnaires with complete responses. For the Guidelines, 39.0% of small-sized (less than 50 employees) businesses answered, "never even heard of the name," while many medium-sized (50-99 employees) and large-sized (100 or more employees) businesses answered that they had heard of the name but did not exactly know about it (33.3% of medium-sized businesses and 47.8% of large-sized businesses). Regarding the system that subsidizes the expenses required for the improvement of a working environment for older workers to work safely and securely (hereinafter referred to as the subsidy system), many businesses of all sizes answered that they had "never even heard of the name." In the comprehensive management of safety and health, half of the businesses of all sizes had developed a system that made it easy to consult about the risk against occupational accidents of older workers. Regardless of size, more than half of businesses were able to consider working conditions and workers. However, there were only a few items where more than half of the businesses considered workload reduction, work posture, work environment, and safety and health, regardless of business size. It became clear that workplace improvement had not progressed very much. Conclusions: These results suggest that to promote workplace improvement that considers older workers, it is necessary to disseminate the Guidelines and proactively take on workplace improvement by utilizing the subsidy system.
MeSH term(s)	Humans ; Japan ; Workplace ; Occupational Health ; Working Conditions ; Surveys and Questionnaires
Language	Japanese
Publishing date	2023-06-23
Publishing country	Japan
Document type	English Abstract ; Journal Article
ZDB-ID	1234922-7
ISSN	1349-533X ; 1341-0725
ISSN (online)	1349-533X
ISSN	1341-0725
DOI	10.1539/sangyoeisei.2023-002-E
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Article ; Online: Identification and enzymatic properties of arginine decarboxylase from

Murakami, Yui / Ikuta, Soichiro / Fukuda, Wakao / Akasaka, Naoki / Maruyama, Jun-Ichi / Shinma, Shuichi / Fukusaki, Eiichiro / Fujiwara, Shinsuke

Applied and environmental microbiology

2024 , Page(s) e0029424

Abstract: Aspergillus ... ...

Abstract	Aspergillus oryzae
Language	English
Publishing date	2024-04-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	223011-2
ISSN	1098-5336 ; 0099-2240
ISSN (online)	1098-5336
ISSN	0099-2240
DOI	10.1128/aem.00294-24
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Article: Clinical Characteristics of the Cleft Lip and/or Palate: Association with Congenital Anomalies, Syndromes, and Chromosomal Anomalies.

Fujii, Nobuyuki / Doi, Rieko / Narai, Takashi / Chiuriki, Naoki / Ikuta, Mika / Kodani, Isamu

Yonago acta medica

2023 Volume 66, Issue 4, Page(s) 440–447

Abstract: Background: Cleft lip and/or palate (CL/P) can be accompanied by other congenital anomalies. We conducted a long-term evaluation of the associations between cleft patterns, sex distribution, and accompanying congenital anomalies of patients with CL/P.!## ...

Abstract	Background: Cleft lip and/or palate (CL/P) can be accompanied by other congenital anomalies. We conducted a long-term evaluation of the associations between cleft patterns, sex distribution, and accompanying congenital anomalies of patients with CL/P. Methods: The medical records of 739 patients with CL/P, seen between January 1967 and December 2020, were retrospectively reviewed. Fisher's exact test was used for statistical analysis. Results: Among the 739 patients with CL/P, the male-to-female ratio was 1.1. Regarding the cleft pattern, 121 (16.4%), 104 (14.1%), 280 (37.9%), 198 (26.8%), and 36 (4.9%) patients had cleft lip (CL), cleft lip and alveolus (CLA), cleft lip and palate (CLP), cleft palate (CP), and submucous cleft palate (SMCP), respectively. Congenital anomalies were identified in 107 (14.5%) cases, of which 53 (49.5%) had congenital heart disease. The frequencies of congenital anomalies patients with in CL/P were 14/225 (6.2%), 36/280 (12.9%), 43/198 (21.7%), and 14/36 (38.9%) for a combination of CL and CLA, CLP, CP, and SMCP, respectively. Accompanying syndromes and chromosomal anomalies were identified in 40 (5.4%) cases, in which Pierre Robin sequence (16 cases of CP and 4 cases of SMCP) was the most frequent. Conclusion: No sex differences were observed in CL/P, and CLP and CP were the most common cleft patterns. Congenital anomalies associated with CL/P were dominated by congenital heart disease and were most frequently identified in CP and SMCP cases. Notably, the Pierre Robin sequence, a complex syndrome characterized by micrognathia, glossoptosis, respiratory obstruction, and a U- or V-shaped CP, was found in cases of both CP and SMCP, and accounted for the symptoms in most cases.
Language	English
Publishing date	2023-11-28
Publishing country	Japan
Document type	Journal Article
ZDB-ID	840719-8
ISSN	1346-8049 ; 0513-5710
ISSN (online)	1346-8049
ISSN	0513-5710
DOI	10.33160/yam.2023.11.009
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Article ; Online: A Case of Spinal Infectious Osteomyelitis Versus Gout: Advanced Imaging with Dual Energy CT.

Seifert, Kimberly D / Zohrabian, Vahe M / Ikuta, Ichiro

The Yale journal of biology and medicine

2021 Volume 94, Issue 4, Page(s) 599–602

Abstract: A 67-year-old male presented to the hospital for lower back pain and left lower extremity radiculopathy. Although the patient was afebrile and white blood cell count was normal, MRI was concerning for discitis/osteomyelitis at L4-L5. Subsequently, the ... ...

Abstract	A 67-year-old male presented to the hospital for lower back pain and left lower extremity radiculopathy. Although the patient was afebrile and white blood cell count was normal, MRI was concerning for discitis/osteomyelitis at L4-L5. Subsequently, the patient developed a right knee joint effusion and underwent an arthrocentesis that was notable for the presence of urate crystals. A systemic urate crystal arthropathy was proposed as a potential etiology for the patient's back pain and radiculopathy. Dual energy CT of the lumbar spine was performed, a technique which determines material composition by comparing the photon attenuation of the substance from two different x-ray energy levels. Results revealed the presence of monosodium urate crystals in the intervertebral discs. This technique is proposed as a noninvasive way to evaluate for gout in atypical locations or those difficult to sample and may replace an invasive intervertebral disc/endplate aspiration and/or biopsy. Dual energy CT should be considered in patients with elevated serum uric acid and concern for spinal involvement of gout.
MeSH term(s)	Aged ; Gout/diagnostic imaging ; Humans ; Male ; Osteomyelitis/diagnostic imaging ; Tomography, X-Ray Computed ; Uric Acid
Chemical Substances	Uric Acid (268B43MJ25)
Language	English
Publishing date	2021-12-29
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	200515-3
ISSN	1551-4056 ; 0044-0086
ISSN (online)	1551-4056
ISSN	0044-0086
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Article ; Online: Superior detection of significant prostate cancer by transperineal prostate biopsy using MRI-transrectal ultrasound fusion image guidance over cognitive registration.

Ito, Masaya / Yonese, Ichiro / Toide, Masahiro / Ikuta, Shuzo / Kobayashi, Shuichiro / Koga, Fumitaka

International journal of clinical oncology

2023 Volume 28, Issue 11, Page(s) 1545–1553

Abstract: Background: The BioJet system allows the fusion of magnetic resonance imaging (MRI) images with real-time transrectal ultrasonography to accurately direct biopsy needles to the target lesions. To date, the superiority of targeted biopsy using the BioJet ...

Abstract	Background: The BioJet system allows the fusion of magnetic resonance imaging (MRI) images with real-time transrectal ultrasonography to accurately direct biopsy needles to the target lesions. To date, the superiority of targeted biopsy using the BioJet system over cognitive registration remains unknown. Methods: This retrospective study included 171 biopsy-naïve men with elevated prostate-specific antigen (2.5-20 ng/mL) and MRI-positive lesions; 74 and 97 men underwent a four-core targeted biopsy per MRI-positive target lesion and a 14-core systematic biopsy transperineally using the BioJet system and cognitive registration, respectively. Detection rates of significant cancer, defined as grade group ≥ 2 or maximum cancer length ≥ 5 mm, were compared between the BioJet system and cognitive registration using propensity score matching and a multivariate logistic regression model. Results: After propensity score matching (67 men for each group), the detection rates of significant cancer were significantly higher in the BioJet group than in the cognitive group for both targeted (76% vs. 46%, P = 0.002) and systematic (70% vs. 46%, P = 0.018) biopsy. Multivariate analysis of the entire cohort also showed that the BioJet system was independently associated with significant cancer detection by targeted and systematic biopsy (P < 0.01), along with a higher prostate-specific antigen density and a higher prostate imaging reporting and data system score. Conclusions: Transperineal prostate biopsy using the BioJet system is superior to cognitive registration in detecting significant cancer for targeted and systematic biopsies.
MeSH term(s)	Male ; Humans ; Prostate/diagnostic imaging ; Prostate/pathology ; Prostate-Specific Antigen ; Retrospective Studies ; Image-Guided Biopsy/methods ; Ultrasonography, Interventional/methods ; Prostatic Neoplasms/pathology ; Ultrasonography ; Magnetic Resonance Imaging/methods ; Cognition
Chemical Substances	Prostate-Specific Antigen (EC 3.4.21.77)
Language	English
Publishing date	2023-08-22
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1400227-9
ISSN	1437-7772 ; 1341-9625
ISSN (online)	1437-7772
ISSN	1341-9625
DOI	10.1007/s10147-023-02404-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Application of artificial intelligence centric workflows for evaluation of neuroradiology emergencies.

Shakoor, Delaram / Al-Dasuqi, Khalid / Cavallo, Joe / Ikuta, Ichiro / Payabvash, Syedmehdi / Malhotra, Ajay

Clinical imaging

2023 Volume 101, Page(s) 133–136

Abstract: The goal of this study was to perform a pilot study to assess user-interface of radiologists with an artificial-intelligence (AI) centric workflow for detection of intracranial hemorrhage (ICH) and cervical spine fractures (CSFX). Over 12-month period, ... ...

Abstract	The goal of this study was to perform a pilot study to assess user-interface of radiologists with an artificial-intelligence (AI) centric workflow for detection of intracranial hemorrhage (ICH) and cervical spine fractures (CSFX). Over 12-month period, interaction and usage of AI software implemented in our institution, Aidoc, on head and cervical spine CT scans were obtained. Several interaction variables were defined, assessing different types of interaction between readers of different training level and AI software. The median usage of AI-centric workflow for detection of ICH and CSFX were 28.8% and 21.8%, respectively, demonstrating a significant additional engagement beyond Native workflow (worklist and PACS). Further studies are warranted to expand interaction assessments to further understand the value unlocked by the AI-centric workflows.
MeSH term(s)	Humans ; Artificial Intelligence ; Workflow ; Emergencies ; Pilot Projects ; Software ; Spinal Fractures
Language	English
Publishing date	2023-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2023.04.004
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