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  1. Article ; Online: Overview: Chronic Pain and Cannabis-Based Medicines.

    Karst, Matthias

    Pharmacopsychiatry

    2024  

    Abstract: Chronic pain is primarily conceptualized as a disease in its own right when it is associated with emotional distress and functional impairment. Pathophysiologically, dysfunction of the cortico-mesolimbic connectome is of major importance, with ... ...

    Abstract Chronic pain is primarily conceptualized as a disease in its own right when it is associated with emotional distress and functional impairment. Pathophysiologically, dysfunction of the cortico-mesolimbic connectome is of major importance, with overlapping signals in the nociceptive and stress systems. The endocannabinoid system plays an important role in the central processing of nociceptive signals and regulates the central stress response. Clinically, there is moderate evidence that cannabis-based medicines (CBM) can contribute to a significant reduction in pain, especially the associated pain affect, and improvement in physical function and sleep quality in a proportion of patients with chronic pain. The analgesic effect appears to be largely independent of the cause of pain. In this context, CBM preferentially regulates stress-associated pain processing.
    Language English
    Publishing date 2024-01-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605670-2
    ISSN 1439-0795 ; 0720-4280 ; 0176-3679
    ISSN (online) 1439-0795
    ISSN 0720-4280 ; 0176-3679
    DOI 10.1055/a-2231-6630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Das Schmerz-Buch

    Karst, Matthias

    neue Wege wagen ; so können Schmerzen überwunden werden

    2014  

    Author's details Matthias Karst
    Language German
    Size 152 S. : Ill., graph. Darst., 210 mm x 155 mm
    Publisher Schlütersche
    Publishing place Hannover
    Publishing country Germany
    Document type Book
    HBZ-ID HT018415751
    ISBN 978-3-89993-850-0 ; 3-89993-850-X ; 9783842685086 ; 3842685084
    Database Catalogue ZB MED Medicine, Health

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  3. Article: Overview: Chronic Pain and Cannabis-Based Medicines

    Karst, Matthias

    Pharmacopsychiatry

    2024  

    Abstract: Chronic pain is primarily conceptualized as a disease in its own right when it is associated with emotional distress and functional impairment. Pathophysiologically, dysfunction of the cortico-mesolimbic connectome ...

    Abstract Chronic pain is primarily conceptualized as a disease in its own right when it is associated with emotional distress and functional impairment. Pathophysiologically, dysfunction of the cortico-mesolimbic connectome is of major importance, with overlapping signals in the nociceptive and stress systems. The endocannabinoid system plays an important role in the central processing of nociceptive signals and regulates the central stress response. Clinically, there is moderate evidence that cannabis-based medicines (CBM) can contribute to a significant reduction in pain, especially the associated pain affect, and improvement in physical function and sleep quality in a proportion of patients with chronic pain. The analgesic effect appears to be largely independent of the cause of pain. In this context, CBM preferentially regulates stress-associated pain processing.
    Keywords cannabis-based medicines ; chronic pain ; chronic stress ; central sensitization ; nociplastic pain
    Language English
    Publishing date 2024-01-10
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605670-2
    ISSN 1439-0795 ; 0176-3679 ; 0720-4280
    ISSN (online) 1439-0795
    ISSN 0176-3679 ; 0720-4280
    DOI 10.1055/a-2231-6630
    Database Thieme publisher's database

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  4. Article ; Online: Cannabinoide zur Therapie chronischer Nervenschmerzen und Spastik.

    Karst, Matthias

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue Suppl 1, Page(s) 51–60

    Title translation Cannabinoids for the treatment of chronic neuropathic pain and spasticity.
    MeSH term(s) Cannabinoids/adverse effects ; Humans ; Neuralgia/drug therapy
    Chemical Substances Cannabinoids
    Language German
    Publishing date 2022-03-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-022-0828-9
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  5. Article ; Online: Cannabis – Es geht ums Ganze!

    Karst, Matthias

    Der Anaesthesist

    2021  Volume 70, Issue 7, Page(s) 549–550

    Title translation Cannabis- Summing it all up!
    MeSH term(s) Cannabis ; Follow-Up Studies ; Humans
    Language German
    Publishing date 2021-07-07
    Publishing country Germany
    Document type Editorial
    ZDB-ID 260-4
    ISSN 1432-055X ; 0003-2417
    ISSN (online) 1432-055X
    ISSN 0003-2417
    DOI 10.1007/s00101-021-01004-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Thesis: Untersuchung eines sensitivierenden Stimulus auf periphere sensorische Neuronen im Sonnenbrandmodell

    Knitsch, Johanna / Karst, Matthias

    2017  

    Institution Medizinische Hochschule Hannover
    Klinik für Anästhesiologie und Intensivmedizin
    Author's details vorgelegt von Johanna Knitsch
    Language German
    Size 2 ungezählte Blätter, 65 Blätter, Illustrationen, Diagramme
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2018
    HBZ-ID HT019725249
    Database Catalogue ZB MED Medicine, Health

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  7. Article: Chronische Schmerzen: Wie und wann wirkt Cannabis?

    Karst, Matthias

    Der Allgemeinarzt

    2019  Volume 41, Issue 9, Page(s) 48

    Language German
    Document type Article
    ZDB-ID 603653-3
    ISSN 0172-7249
    Database Current Contents Medicine

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  8. Article ; Online: Contiguous Silver(I)-Mediated Base Pairs of Imidazophenanthroline and Canonical Nucleobases in DNA Duplexes: Formation of Classical Duplexes versus Homodimer Formation.

    Lefringhausen, Nils / Erbacher, Catharina / Elinkmann, Matthias / Karst, Uwe / Müller, Jens

    Bioconjugate chemistry

    2023  Volume 35, Issue 1, Page(s) 99–106

    Abstract: Metal-mediated base pairs represent a topical alternative to canonical hydrogen-bonded base pairs. In this context, the ligand ... ...

    Abstract Metal-mediated base pairs represent a topical alternative to canonical hydrogen-bonded base pairs. In this context, the ligand 1
    MeSH term(s) Base Pairing ; Silver/chemistry ; Models, Molecular ; DNA/chemistry ; Oligonucleotides/chemistry
    Chemical Substances Silver (3M4G523W1G) ; DNA (9007-49-2) ; Oligonucleotides
    Language English
    Publishing date 2023-12-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1024041-x
    ISSN 1520-4812 ; 1043-1802
    ISSN (online) 1520-4812
    ISSN 1043-1802
    DOI 10.1021/acs.bioconjchem.3c00494
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  9. Book ; Online ; Thesis: Das Zusammenspiel von chronischem Stress und genetischen Merkmalen unterscheidet zwischen Patienten, die an einer multisomatoformen Störung mit Schmerz als Leitsymptom leiden, und einer gesunden Kontrollgruppe

    Buhck, Miro [Verfasser] / Karst, Matthias [Akademischer Betreuer]

    2023  

    Author's details Miro Delano Buhck ; Akademischer Betreuer: Matthias Karst ; Klinik für Anästhesiologie und Intensivmedizin
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Bibliothek der Medizinischen Hochschule Hannover
    Publishing place Hannover
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Article ; Online: EMG measured reaction time as a predictor of invalid symptom report in psychosomatic patients.

    Weymann, Thorben / Achenbach, Johannes / Guevara, Jasmin E / Bassler, Markus / Karst, Matthias / Lambrecht, Alexandra

    The Clinical neuropsychologist

    2023  , Page(s) 1–17

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-11-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 639080-8
    ISSN 1744-4144 ; 0920-1637 ; 1385-4046
    ISSN (online) 1744-4144
    ISSN 0920-1637 ; 1385-4046
    DOI 10.1080/13854046.2023.2276480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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