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  1. Article ; Online: Brain Functional Imaging Anatomy.

    Vachha, Behroze Adi / Middlebrooks, Erik H

    Neuroimaging clinics of North America

    2022  Volume 32, Issue 3, Page(s) 491–505

    Abstract: Human brain function is an increasingly complex framework that has important implications in clinical medicine. In this review, the anatomy of the most commonly assessed brain functions in clinical neuroradiology, including motor, language, and vision, ... ...

    Abstract Human brain function is an increasingly complex framework that has important implications in clinical medicine. In this review, the anatomy of the most commonly assessed brain functions in clinical neuroradiology, including motor, language, and vision, is discussed. The anatomy and function of the primary and secondary sensorimotor areas are discussed with clinical case examples. Next, the dual stream of language processing is reviewed, as well as its implications in clinical medicine and surgical planning. Last, the authors discuss the striate and extrastriate visual cortex and review the dual stream model of visual processing.
    MeSH term(s) Brain Mapping/methods ; Humans ; Language ; Magnetic Resonance Imaging/methods ; Sensorimotor Cortex
    Language English
    Publishing date 2022-05-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1314594-0
    ISSN 1557-9867 ; 1052-5149
    ISSN (online) 1557-9867
    ISSN 1052-5149
    DOI 10.1016/j.nic.2022.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: BOLD asynchrony: An imaging biomarker of tumor burden in IDH-mutated gliomas.

    Vachha, Behroze Adi / Huang, Raymond Y

    Neuro-oncology

    2021  Volume 24, Issue 1, Page(s) 88–89

    MeSH term(s) Biomarkers ; Glioma/genetics ; Humans ; Isocitrate Dehydrogenase/genetics ; Tumor Burden
    Chemical Substances Biomarkers ; Isocitrate Dehydrogenase (EC 1.1.1.41)
    Language English
    Publishing date 2021-10-25
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noab248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: MRI with ultrahigh field strength and high-performance gradients: challenges and opportunities for clinical neuroimaging at 7 T and beyond.

    Vachha, Behroze / Huang, Susie Y

    European radiology experimental

    2021  Volume 5, Issue 1, Page(s) 35

    Abstract: Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provides an overview of the technical advantages ... ...

    Abstract Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provides an overview of the technical advantages and challenges of performing clinical neuroimaging studies at ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology. Emerging clinical applications of 7-T MRI and state-of-the-art gradient systems equipped with up to 300 mT/m gradient strength are reviewed, and the impact and benefits of such advances to anatomical, structural and functional MRI are discussed in a variety of neurological conditions. Finally, an outlook and future directions for ultrahigh field MRI combined with ultrahigh and ultrafast gradient technology in neuroimaging are examined.
    MeSH term(s) Magnetic Resonance Imaging ; Neuroimaging
    Language English
    Publishing date 2021-08-26
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ISSN 2509-9280
    ISSN (online) 2509-9280
    DOI 10.1186/s41747-021-00216-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: Advanced Neuroimaging of Brain Metastases.

    Vachha, Behroze A / Huang, Susie Y / Massoud, Tarik F

    Frontiers in neurology

    2021  Volume 12, Page(s) 668310

    Language English
    Publishing date 2021-03-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.668310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: MRI with ultrahigh field strength and high-performance gradients

    Behroze Vachha / Susie Y. Huang

    European Radiology Experimental, Vol 5, Iss 1, Pp 1-

    challenges and opportunities for clinical neuroimaging at 7 T and beyond

    2021  Volume 18

    Abstract: Abstract Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provides an overview of the technical ... ...

    Abstract Abstract Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provides an overview of the technical advantages and challenges of performing clinical neuroimaging studies at ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology. Emerging clinical applications of 7-T MRI and state-of-the-art gradient systems equipped with up to 300 mT/m gradient strength are reviewed, and the impact and benefits of such advances to anatomical, structural and functional MRI are discussed in a variety of neurological conditions. Finally, an outlook and future directions for ultrahigh field MRI combined with ultrahigh and ultrafast gradient technology in neuroimaging are examined.
    Keywords Epilepsy ; Magnetic fields ; Magnetic resonance imaging ; Multiple sclerosis ; Neuroimaging ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 610
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Anatomy of the Cerebral Cortex, Lobes, and Cerebellum.

    Vachha, Behroze Adi / Massoud, Tarik F / Huang, Susie Y

    Neuroimaging clinics of North America

    2022  Volume 32, Issue 3, Page(s) 463–473

    Abstract: Strong foundational knowledge of the anatomy of the cerebral cortex, lobes, and cerebellum is key to guide the search for potential lesions based on clinical presentation and known focal neurologic deficits. This article provides an introduction and ... ...

    Abstract Strong foundational knowledge of the anatomy of the cerebral cortex, lobes, and cerebellum is key to guide the search for potential lesions based on clinical presentation and known focal neurologic deficits. This article provides an introduction and overview of cerebral cortical anatomy, including the key sulci that divide the 4 lobes of the cerebral cortex, as well as the major gyral and sulcal landmarks within each lobe. The organization of the cerebellum and its major anatomic constituents are also described. Commonly encountered anatomic variants and asymmetries in cerebral cortical anatomy are presented and discussed.
    MeSH term(s) Cerebellum/diagnostic imaging ; Cerebral Cortex/diagnostic imaging ; Humans
    Language English
    Publishing date 2022-05-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1314594-0
    ISSN 1557-9867 ; 1052-5149
    ISSN (online) 1557-9867
    ISSN 1052-5149
    DOI 10.1016/j.nic.2022.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Neuroimaging and Neurocognitive Outcomes in Older Patients with Multiple Myeloma Treated with Chemotherapy and Autologous Stem Cell Transplantation.

    Correa, Denise D / Vachha, Behroze A / Baser, Raymond E / Koch, Adrian / Wong, Phillip / Gohel, Suril / Giralt, Sergio / Root, James C

    Research square

    2023  

    Abstract: Background Many patients with hematological malignancies treated with stem cell transplantation (SCT) experience cognitive dysfunction. However, few studies have investigated treatment-related neurotoxicity in older adults with multiple myeloma (MM) ... ...

    Abstract Background Many patients with hematological malignancies treated with stem cell transplantation (SCT) experience cognitive dysfunction. However, few studies have investigated treatment-related neurotoxicity in older adults with multiple myeloma (MM) treated with high dose chemotherapy (HDC) and autologous SCT (HDC/ASCT). In this study, we examined gray matter (GM) volume, resting state functional connectivity (RSFC), neurocognitive function (NF), and proinflammatory cytokines (PCy) in older patients with MM pre- and post-HDC/ASCT. Methods Eighteen MM patients underwent magnetic resonance imaging, neurocognitive tests, and serum PCy measurement prior to HDC/ASCT, and fifteen patients completed follow ups an average of five months post-HDC/ASCT. Results There were significant decreases in RSFC from pre- to post-HDC/ASCT in (1) the central executive network (CEN) involving the
    Language English
    Publishing date 2023-04-05
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-2733807/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Neuroimaging and Neurocognitive Outcomes in Older Patients with Multiple Myeloma Treated with Chemotherapy and Autologous Stem Cell Transplantation.

    Correa, Denise D / Vachha, Behroze A / Baser, Raymond E / Koch, Adrian / Wong, Phillip / Gohel, Suril / Giralt, Sergio / Root, James C

    Cancers

    2023  Volume 15, Issue 18

    Abstract: There is a paucity of research on treatment-related neurotoxicity in older adults with multiple myeloma (MM) treated with high-dose chemotherapy (HDC) and autologous SCT (HDC/ASCT), despite the increasing use of this regimen. We examined resting state ... ...

    Abstract There is a paucity of research on treatment-related neurotoxicity in older adults with multiple myeloma (MM) treated with high-dose chemotherapy (HDC) and autologous SCT (HDC/ASCT), despite the increasing use of this regimen. We examined resting state functional connectivity (RSFC), gray matter (GM) volume, neurocognitive function (NF), and proinflammatory cytokines (PCy) in older patients with MM pre- and post-HDC/ASCT. Eighteen patients underwent MRI, NF tests, and serum PCy measurements prior to HDC/ASCT, and fifteen patients completed a follow up five-months post-HDC/ASCT. There were significant decreases in RSFC post-HDC/ASCT in (1) the central executive network (CEN) involving the
    Language English
    Publishing date 2023-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15184484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Current methods and new directions in resting state fMRI.

    Yang, Jackie / Gohel, Suril / Vachha, Behroze

    Clinical imaging

    2020  Volume 65, Page(s) 47–53

    Abstract: Resting state functional connectivity magnetic resonance imaging (rsfcMRI) has become a key component of investigations of neurocognitive and psychiatric behaviors. Over the past two decades, several methods and paradigms have been adopted to utilize and ...

    Abstract Resting state functional connectivity magnetic resonance imaging (rsfcMRI) has become a key component of investigations of neurocognitive and psychiatric behaviors. Over the past two decades, several methods and paradigms have been adopted to utilize and interpret data from resting-state fluctuations in the brain. These findings have increased our understanding of changes in many disease states. As the amount of resting state data available for research increases with big datasets and data-sharing projects, it is important to review the established traditional analysis methods and recognize areas where research methodology can be adapted to better accommodate the scale and complexity of rsfcMRI analysis. In this paper, we review established methods of analysis as well as areas that have been receiving increasing attention such as dynamic rsfcMRI, independent vector analysis, multiband rsfcMRI and network of networks.
    MeSH term(s) Adult ; Brain/physiopathology ; Brain Mapping/methods ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Nerve Net/physiopathology ; Rest
    Language English
    Publishing date 2020-04-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2020.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Imaging of Pediatric Orbital Diseases.

    Vachha, Behroze A / Robson, Caroline D

    Neuroimaging clinics of North America

    2015  Volume 25, Issue 3, Page(s) 477–501

    Abstract: This article reviews a variety of congenital and developmental disorders of the pediatric orbit with particular emphasis on ocular lesions, followed by a description of developmental and neoplastic orbital and ocular masses. The relationship of these ... ...

    Abstract This article reviews a variety of congenital and developmental disorders of the pediatric orbit with particular emphasis on ocular lesions, followed by a description of developmental and neoplastic orbital and ocular masses. The relationship of these diseases to various syndromes and/or known genetic mutations is also highlighted.
    MeSH term(s) Bone Diseases/diagnosis ; Eye Diseases/diagnosis ; Humans ; Magnetic Resonance Imaging/methods ; Neuroimaging/methods ; Orbit/diagnostic imaging ; Orbit/pathology ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2015-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1314594-0
    ISSN 1557-9867 ; 1052-5149
    ISSN (online) 1557-9867
    ISSN 1052-5149
    DOI 10.1016/j.nic.2015.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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