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  1. Article ; Online: Psychotropic Drug Treatment Patterns in Persons with Fragile X Syndrome.

    Dominick, Kelli C / Andrews, Howard F / Kaufmann, Walter E / Berry-Kravis, Elizabeth / Erickson, Craig A

    Journal of child and adolescent psychopharmacology

    2021  Volume 31, Issue 10, Page(s) 659–669

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Attention Deficit Disorder with Hyperactivity/drug therapy ; Attention Deficit Disorder with Hyperactivity/epidemiology ; Autism Spectrum Disorder/drug therapy ; Autism Spectrum Disorder/epidemiology ; Comorbidity ; Fragile X Syndrome/drug therapy ; Fragile X Syndrome/epidemiology ; Humans ; Male ; Psychotropic Drugs/therapeutic use
    Chemical Substances Psychotropic Drugs
    Language English
    Publishing date 2021-11-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1055410-5
    ISSN 1557-8992 ; 1044-5463
    ISSN (online) 1557-8992
    ISSN 1044-5463
    DOI 10.1089/cap.2021.0042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3091: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Lingual compression for acute macroglossia in a COVID-19 positive patient.

    Andrews, Erickson / Lezotte, Jonathan / Ackerman, Adam M

    BMJ case reports

    2020  Volume 13, Issue 7

    Abstract: We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results. ...

    Abstract We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results.
    MeSH term(s) Acute Disease ; Adult ; Betacoronavirus ; COVID-19 ; Compression Bandages ; Coronavirus Infections/complications ; Female ; Humans ; Macroglossia/complications ; Macroglossia/etiology ; Macroglossia/therapy ; Pandemics ; Patient Positioning/adverse effects ; Patient Positioning/methods ; Pneumonia, Viral/complications ; SARS-CoV-2 ; Saline Solution/therapeutic use ; Tongue
    Chemical Substances Saline Solution
    Keywords covid19
    Language English
    Publishing date 2020-07-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-237108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Direct early growth response-1 knockdown decreases melanoma viability independent of mitogen-activated extracellular signal-related kinase inhibition.

    Miley, David R / Andrews-Pfannkoch, Cynthia M / Pulido, Jose S / Erickson, Samantha A / Vile, Richard G / Fautsch, Michael P / Marmorstein, Alan D / Dalvin, Lauren A

    Melanoma research

    2023  Volume 33, Issue 6, Page(s) 482–491

    Abstract: To investigate downstream molecular changes caused by mitogen-activated protein kinase (MEK) inhibitor treatment and further explore the impact of direct knockdown of early growth response-1 ( EGR1 ) in melanoma cell culture. RNA-sequencing (RNA-Seq) was ...

    Abstract To investigate downstream molecular changes caused by mitogen-activated protein kinase (MEK) inhibitor treatment and further explore the impact of direct knockdown of early growth response-1 ( EGR1 ) in melanoma cell culture. RNA-sequencing (RNA-Seq) was performed to determine gene expression changes with MEK inhibitor treatment. Treatment with MEK inhibitor (trametinib) was then assessed in two cutaneous (MEL888, MEL624) and one conjunctival (YUARGE 13-3064) melanoma cell line. Direct knockdown of EGR1 was accomplished using lentiviral vectors containing shRNA. Cell viability was measured using PrestoBlueHS Cell Viability Reagent. Total RNA and protein were assessed by qPCR and SimpleWestern. RNA-Seq demonstrated a profound reduction in EGR1 with MEK inhibitor treatment, prompting further study of melanoma cell lines. Following trametinib treatment of melanoma cells, viability was reduced in both cutaneous (MEL888 26%, P  < 0.01; MEL624 27%, P  < 0.001) and conjunctival (YUARGE 13-3064 33%, P  < 0.01) melanoma compared with DMSO control, with confirmed EGR1 knockdown to 0.04-, 0.01-, and 0.16-fold DMSO-treated levels (all P  < 0.05) in MEL888, MEL624, and YUARGE 13-3064, respectively. Targeted EGR1 knockdown using shRNA reduced viability in both cutaneous (MEL624 78%, P  = 0.05) and conjunctival melanoma (YUARGE-13-3064 67%, P  = 0.02). RNA-Sequencing in MEK inhibitor-treated cells identified EGR1 as a candidate effector molecule of interest. In a malignant melanoma cell population, MEK inhibition reduced viability in both cutaneous and conjunctival melanoma with a profound downstream reduction in EGR1 expression. Targeted knockdown of EGR1 reduced both cutaneous and conjunctival melanoma cell viability independent of MEK inhibition, suggesting a key role for EGR1 in melanoma pathobiology.
    MeSH term(s) Humans ; Melanoma/drug therapy ; Melanoma/genetics ; Melanoma/metabolism ; Mitogens ; Dimethyl Sulfoxide ; Skin Neoplasms/drug therapy ; Skin Neoplasms/genetics ; Skin Neoplasms/pathology ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Protein Kinase Inhibitors/pharmacology ; Mitogen-Activated Protein Kinase Kinases ; RNA, Small Interfering ; Cell Line, Tumor ; Proto-Oncogene Proteins B-raf/genetics
    Chemical Substances Mitogens ; Dimethyl Sulfoxide (YOW8V9698H) ; Extracellular Signal-Regulated MAP Kinases (EC 2.7.11.24) ; Protein Kinase Inhibitors ; Mitogen-Activated Protein Kinase Kinases (EC 2.7.12.2) ; RNA, Small Interfering ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1)
    Language English
    Publishing date 2023-08-25
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1095779-0
    ISSN 1473-5636 ; 0960-8931
    ISSN (online) 1473-5636
    ISSN 0960-8931
    DOI 10.1097/CMR.0000000000000921
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3378: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Factor Structure of the Aberrant Behavior Checklist in Individuals with Fragile X Syndrome: Clarifications and Future Guidance.

    Aman, Michael G / Norris, Megan / Kaat, Aaron J / Andrews, Howard / Choo, Tse-Hwei / Chen, Chen / Wheeler, Anne / Bann, Carla / Erickson, Craig

    Journal of child and adolescent psychopharmacology

    2020  Volume 30, Issue 8, Page(s) 512–521

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Algorithms ; Anxiety ; Checklist/standards ; Child ; Factor Analysis, Statistical ; Female ; Fragile X Syndrome/complications ; Humans ; Irritable Mood ; Male ; Mental Disorders/complications ; Problem Behavior ; Social Adjustment
    Language English
    Publishing date 2020-08-03
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Observational Study ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 1055410-5
    ISSN 1557-8992 ; 1044-5463
    ISSN (online) 1557-8992
    ISSN 1044-5463
    DOI 10.1089/cap.2019.0177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3091: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Lingual compression for acute macroglossia in a COVID-19 positive patient

    Andrews, Erickson / Lezotte, Jonathan / Ackerman, Adam M

    BMJ case reports

    Abstract: We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results. ...

    Abstract We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #650048
    Database COVID19

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  6. Book ; Online: Lingual compression for acute macroglossia in a COVID-19 positive patient

    Andrews, Erickson / Lezotte, Jonathan / Ackerman, Adam M

    Orthopaedics Articles

    2020  

    Abstract: We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results. ...

    Abstract We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results.
    Keywords Acute Disease ; Adult ; Betacoronavirus ; Compression Bandages ; Coronavirus Infections ; Female ; Humans ; Macroglossia ; Pandemics ; Patient Positioning ; Pneumonia ; Viral ; Saline Solution ; Tongue ; covid19
    Publishing date 2020-07-16T07:00:00Z
    Publisher Henry Ford Health System Scholarly Commons
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Lingual compression for acute macroglossia in a COVID-19 positive patient

    Andrews, Erickson / Lezotte, Jonathan / Ackerman, Adam M

    BMJ Case Reports

    2020  Volume 13, Issue 7, Page(s) e237108

    Abstract: We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results. ...

    Abstract We describe a 40-year-old woman with severe, persistent macroglossia following prone positioning as part of treatment for COVID-19. We used the treatment method of lingual compression with satisfactory results.
    Keywords covid19
    Language English
    Publisher BMJ
    Publishing country uk
    Document type Article ; Online
    ISSN 1757-790X
    DOI 10.1136/bcr-2020-237108
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Validation of noninvasive body-surface gastric mapping for detecting gastric slow-wave spatiotemporal features by simultaneous serosal mapping in porcine.

    Calder, Stefan / Cheng, Leo K / Andrews, Christopher N / Paskaranandavadivel, Niranchan / Waite, Stephen / Alighaleh, Saeed / Erickson, Jonathan C / Gharibans, Armen / O'Grady, Gregory / Du, Peng

    American journal of physiology. Gastrointestinal and liver physiology

    2022  Volume 323, Issue 4, Page(s) G295–G305

    Abstract: Gastric disorders are increasingly prevalent, but reliable noninvasive tools to objectively assess gastric function are lacking. Body-surface gastric mapping (BSGM) is a noninvasive method for the detection of gastric electrophysiological features, which ...

    Abstract Gastric disorders are increasingly prevalent, but reliable noninvasive tools to objectively assess gastric function are lacking. Body-surface gastric mapping (BSGM) is a noninvasive method for the detection of gastric electrophysiological features, which are correlated with symptoms in patients with gastroparesis and functional dyspepsia. Previous studies have validated the relationship between serosal and cutaneous recordings from limited number of channels. This study aimed to comprehensively evaluate the basis of BSGM from 64 cutaneous channels and reliably identify spatial biomarkers associated with slow-wave dysrhythmias. High-resolution electrode arrays were placed to simultaneously capture slow waves from the gastric serosa (32 × 6 electrodes at 4 mm spacing) and epigastrium (8 × 8 electrodes at 20 mm spacing) in 14 porcine subjects. BSGM signals were processed based on a combination of wavelet and phase information analyses. A total of 1,185 individual cycles of slow waves were assessed, out of which 897 (76%) were classified as normal antegrade waves, occurring in 10 (71%) subjects studied. BSGM accurately detected the underlying slow wave in terms of frequency (
    MeSH term(s) Animals ; Electrodes ; Electrophysiological Phenomena ; Gastrointestinal Motility/physiology ; Gastroparesis ; Humans ; Serous Membrane/physiology ; Stomach/physiology ; Swine
    Language English
    Publishing date 2022-08-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603840-2
    ISSN 1522-1547 ; 0193-1857
    ISSN (online) 1522-1547
    ISSN 0193-1857
    DOI 10.1152/ajpgi.00049.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uc I Zs.89: Show issues Location:
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  9. Article: Concussions in the National Hockey League: Analysis of Incidence, Return to Play, and Performance.

    Andrews, Erickson / Jildeh, Toufic R / Abbas, Muhammad J / Lindsay-Rivera, Kevin / Berguson, Jon / Okoroha, Kelechi R

    Orthopaedic journal of sports medicine

    2022  Volume 10, Issue 1, Page(s) 23259671211052069

    Abstract: Background: Concussion injuries are common in professional hockey; however, their effect on player performance remains unclear.: Purpose: To quantify the effect of concussions on the performance of position players in the National Hockey League (NHL). ...

    Abstract Background: Concussion injuries are common in professional hockey; however, their effect on player performance remains unclear.
    Purpose: To quantify the effect of concussions on the performance of position players in the National Hockey League (NHL).
    Study design: Cohort study; Level of evidence, 3.
    Methods: Concussion data from the NHL were collected using publicly available databases for the seasons between 2009-2010 and 2015-2016, coinciding with new NHL concussion rules. Age, body mass index, position, number of concussions during a player's NHL career, games played, and time on ice were recorded. Basic and advanced performance metrics were collected for 1 season pre- and postconcussion (short-term period) and 3 seasons before and after concussion (long-term period) to assess short- and long-term changes in performance. A control group of players without an identified concussion who competed during the study period was assembled for comparison. Wilcoxon signed rank tests were used to evaluate pre- to postconcussion data in the short- and long-term settings as well as to compare the cohorts at each time point.
    Results: Overall, 48 players were identified as having a concussion during the study period. Players missed 17.2 ± 15.1 days (mean ± standard deviation) and 7.5 ± 6.9 games postconcussion. There were no significant differences in any metric when pre- and postconcussion intraseason performance was assessed. Athletes who were concussed demonstrated significantly deceased performance metrics (assists per 60 minutes, points per 60 minutes, Corsi percentage, and Fenwick percentage) in the 3 years after the concussion as compared with the year before injury (
    Conclusion: A high rate of NHL players were able to return to play after a concussion injury. Players with concussion did not experience a reduction in performance metrics in the short- or long-term setting when compared with matched controls. The concussed cohort maintained a similar workload up to 3 seasons postconcussion but played in fewer career games when compared with matched controls.
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/23259671211052069
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  10. Article ; Online: Partnerships among community development, public health, and health care could improve the well-being of low-income people.

    Erickson, David / Andrews, Nancy

    Health affairs (Project Hope)

    2011  Volume 30, Issue 11, Page(s) 2056–2063

    Abstract: Safe, vibrant neighborhoods are vital to health. The community development "industry"-a network of nonprofit service providers, real estate developers, financial institutions, foundations, and government-draws on public subsidies and other financing to ... ...

    Abstract Safe, vibrant neighborhoods are vital to health. The community development "industry"-a network of nonprofit service providers, real estate developers, financial institutions, foundations, and government-draws on public subsidies and other financing to transform impoverished neighborhoods into better-functioning communities. Although such activity positively affects the "upstream" causes of poor health, the community development industry rarely collaborates with the health sector or even considers health effects in its work. Examples of initiatives-such as the creation of affordable housing that avoids nursing home placement-suggest a strong potential for cross-sector collaborations to reduce health disparities and slow the growth of health care spending, while at the same time improving economic and social well-being in America's most disadvantaged communities. We propose a four-point plan to help ensure that these collaborations achieve positive outcomes and sustainable progress for residents and investors alike.
    MeSH term(s) Community Networks/economics ; Community Networks/organization & administration ; Environment Design ; Humans ; Personal Satisfaction ; Poverty ; Primary Health Care ; Public Health ; Public-Private Sector Partnerships ; Social Change
    Language English
    Publishing date 2011-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632712-6
    ISSN 1544-5208 ; 0278-2715
    ISSN (online) 1544-5208
    ISSN 0278-2715
    DOI 10.1377/hlthaff.2011.0896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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