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  1. Book: Yeast genetics

    Smith, Jeffrey S. / Burke, Daniel J.

    (Methods in molecular biology ; 1205 ; Springer protocols)

    2014  

    Author's details ed. by Jeffrey S. Smith ; Daniel J. Burke
    Series title Methods in molecular biology ; 1205
    Springer protocols
    Collection
    Language English
    Size XI, 378 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT018408182
    ISBN 978-1-49391-362-6 ; 9781493913633 ; 1-49391-362-X ; 1493913638
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -1205- verfügbar in Königswinter Königswinter

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  2. Article ; Online: Caution at psychiatry's psychedelic frontier.

    Burke, Matthew J / Blumberger, Daniel M

    Nature medicine

    2021  Volume 27, Issue 10, Page(s) 1687–1688

    MeSH term(s) Hallucinogens ; Psychiatry
    Chemical Substances Hallucinogens
    Language English
    Publishing date 2021-10-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-021-01524-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4212: Show issues Location:
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    Zs.MG 39: Show issues

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  3. Article ; Online: Klotho and Clinical Outcomes in CKD.

    Edmonston, Daniel / Fuchs, Michaela A A / Burke, Emily J / Isakova, Tamara / Wolf, Myles

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2024  

    Abstract: Rationale & objective: Klotho deficiency may affect clinical outcomes in chronic kidney disease (CKD) through fibroblast growth factor-23 (FGF23)-dependent and independent pathways. However, the association between circulating Klotho and clinical ... ...

    Abstract Rationale & objective: Klotho deficiency may affect clinical outcomes in chronic kidney disease (CKD) through fibroblast growth factor-23 (FGF23)-dependent and independent pathways. However, the association between circulating Klotho and clinical outcomes in CKD remains unresolved and was the focus of this study.
    Study design: Prospective observational study.
    Setting & participants: 1088 participants of the Chronic Renal Insufficiency Cohort (CRIC) Study with estimated glomerular filtration rate (eGFR) 20-70 ml/min/1.73m
    Exposure: Plasma Klotho level at the year-1 study visit.
    Outcomes: 5-year risks of all-cause mortality, heart failure hospitalization, atherosclerotic cardiovascular events, and a composite kidney endpoint comprised of a sustained 50% decline in eGFR, dialysis, kidney transplantation, or eGFR <15 ml/min/1.73 m
    Analytical approach: We divided Klotho into six groups to account for its non-normal distribution. We used Cox proportional hazards regression and subdistribution hazards models to compare survival and clinical outcomes, respectively, between Klotho groups. We sequentially adjusted for demographics, kidney function, cardiovascular risk factors, sample age, and FGF23.
    Results: Mean eGFR was 42 ml/min/1.73m
    Limitations: Despite adjustments, we cannot exclude potential influence of residual confounding or sample storage on the results. A single measurement of plasma Klotho may not capture Klotho patterns over time.
    Conclusions: In a large, diverse, well-characterized CKD cohort, Klotho was not associated with clinical outcomes, and Klotho deficiency did not confound the association of FGF23 with mortality or heart failure hospitalization.
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2024.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1669: Show issues Location:
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    Zs.MO 468: Show issues

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  4. Article ; Online: Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance.

    Blair, Daniel J / Burke, Martin D

    Nature

    2020  Volume 586, Issue 7827, Page(s) 32–33

    MeSH term(s) Anti-Bacterial Agents ; Drug Resistance, Microbial/drug effects ; Streptogramin Group A
    Chemical Substances Anti-Bacterial Agents ; Streptogramin Group A
    Language English
    Publishing date 2020-09-17
    Publishing country England
    Document type News ; Comment
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-020-02565-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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  5. Article ; Online: Phospholipid cofactor solubilization inhibits formation of native prions.

    Schwind, Abigail M / Walsh, Daniel J / Burke, Cassandra M / Supattapone, Surachai

    Journal of neurochemistry

    2023  Volume 166, Issue 5, Page(s) 875–884

    Abstract: Cofactor molecules are required to generate infectious mammalian prions in vitro. Mouse and hamster prions appear to have different cofactor preferences: Whereas both mouse and hamster prions can use phosphatidylethanolamine (PE) as a prion cofactor, ... ...

    Abstract Cofactor molecules are required to generate infectious mammalian prions in vitro. Mouse and hamster prions appear to have different cofactor preferences: Whereas both mouse and hamster prions can use phosphatidylethanolamine (PE) as a prion cofactor, only hamster prions can also use single-stranded RNA as an alternative cofactor. Here, we investigated the effect of detergent solubilization on rodent prion formation in vitro. We discovered that detergents that can solubilize PE (n-octylglucoside, n-octylgalactoside, and CHAPS) inhibit mouse prion formation in serial protein misfolding cyclic amplification (sPMCA) reactions using bank vole brain homogenate substrate, whereas detergents that are unable to solubilize PE (Triton X-100 and IPEGAL) have no effect. For all three PE-solubilizing detergents, inhibition of RML mouse prion formation was only observed above the critical micellar concentration (CMC). Two other mouse prion strains, Me7 and 301C, were also inhibited by the three PE-solubilizing detergents but not by Triton X-100 or IPEGAL. In contrast, none of the detergents inhibited hamster prion formation in parallel sPMCA reactions using the same bank vole brain homogenate substrate. In reconstituted sPMCA reactions using purified substrates, n-octylglucoside inhibited hamster prion formation when immunopurified bank vole PrP
    MeSH term(s) Cricetinae ; Mice ; Animals ; Prions/metabolism ; Phospholipids ; Octoxynol/pharmacology ; Detergents/pharmacology ; Prion Proteins ; Arvicolinae/genetics ; Arvicolinae/metabolism ; RNA
    Chemical Substances Prions ; Phospholipids ; Octoxynol (9002-93-1) ; Detergents ; Prion Proteins ; RNA (63231-63-0)
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 80158-6
    ISSN 1471-4159 ; 0022-3042 ; 1474-1644
    ISSN (online) 1471-4159
    ISSN 0022-3042 ; 1474-1644
    DOI 10.1111/jnc.15930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Projected future climatic forcing on the global distribution of vegetation types.

    Allen, Bethany J / Hill, Daniel J / Burke, Ariane M / Clark, Michael / Marchant, Robert / Stringer, Lindsay C / Williams, David R / Lyon, Christopher

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2024  Volume 379, Issue 1902, Page(s) 20230011

    Abstract: Most emissions scenarios suggest temperature and precipitation regimes will change dramatically across the globe over the next 500 years. These changes will have large impacts on the biosphere, with species forced to migrate to follow their preferred ... ...

    Abstract Most emissions scenarios suggest temperature and precipitation regimes will change dramatically across the globe over the next 500 years. These changes will have large impacts on the biosphere, with species forced to migrate to follow their preferred environmental conditions, therefore moving and fragmenting ecosystems. However, most projections of the impacts of climate change only reach 2100, limiting our understanding of the temporal scope of climate impacts, and potentially impeding suitable adaptive action. To address this data gap, we model future climate change every 20 years from 2000 to 2500 CE, under different CO
    MeSH term(s) Humans ; Ecosystem ; Biodiversity ; Tundra ; Climate Change ; Temperature
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0080-4622 ; 0264-3839 ; 0962-8436
    ISSN (online) 1471-2970
    ISSN 0080-4622 ; 0264-3839 ; 0962-8436
    DOI 10.1098/rstb.2023.0011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Einzelsignatur: Show issues

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  7. Article: Preparation of MIDA Anhydride and Reaction with Boronic Acids.

    Chen, Peng-Jui / Kelly, Aidan M / Blair, Daniel J / Burke, Martin D

    Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals

    2022  Volume 99, Page(s) 92–112

    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2247669-6
    ISSN 0078-6209
    ISSN 0078-6209
    DOI 10.15227/orgsyn.099.0092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: APC/C and SCF

    Choudhury, Rajarshi / Bonacci, Thomas / Arceci, Anthony / Lahiri, Debojyoti / Mills, Christine A / Kernan, Jennifer L / Branigan, Timothy B / DeCaprio, James A / Burke, Daniel J / Emanuele, Michael J

    Cell reports

    2024  Volume 43, Issue 3, Page(s) 113974

    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2024.113974
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: IFN-γ: A cytokine at the right time, is in the right place.

    Burke, J Daniel / Young, Howard A

    Seminars in immunology

    2019  Volume 43, Page(s) 101280

    Abstract: Interferon gamma has long been studied as a critical mediator of tumor immunity. In recent years, the complexity of cellular interactions that take place in the tumor microenvironment has become better appreciated in the context of immunotherapy. While ... ...

    Abstract Interferon gamma has long been studied as a critical mediator of tumor immunity. In recent years, the complexity of cellular interactions that take place in the tumor microenvironment has become better appreciated in the context of immunotherapy. While checkpoint inhibitors have dramatically improved remission rates in cancer treatment, IFN-γ and related effectors continue to be identified as strong predictors of treatment success. In this review, we provide an overview of the multiple immunosuppressive barriers that IFN-γ has to overcome to eliminate tumors, and potential avenues for modulating the immune response in favor of tumor rejection.
    MeSH term(s) Animals ; Antineoplastic Agents, Immunological/therapeutic use ; Biomarkers, Pharmacological/metabolism ; Humans ; Immune Tolerance ; Immunization ; Immunotherapy/trends ; Interferon-gamma/metabolism ; Neoplasms/immunology ; Neoplasms/therapy ; Tumor Microenvironment
    Chemical Substances Antineoplastic Agents, Immunological ; Biomarkers, Pharmacological ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2019-06-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1018141-6
    ISSN 1096-3618 ; 1044-5323
    ISSN (online) 1096-3618
    ISSN 1044-5323
    DOI 10.1016/j.smim.2019.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2843: Show issues Location:
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  10. Article ; Online: Amplified inversion effects for moving biological stimuli remain largest for faces and bodies.

    Piepers, Daniel W / Stevens, Catherine J / Burke, Darren / Robbins, Rachel A

    Quarterly journal of experimental psychology (2006)

    2021  Volume 74, Issue 12, Page(s) 2046–2056

    Abstract: Turning an object upside-down disrupts our ability to perceive it accurately, and ... ...

    Abstract Turning an object upside-down disrupts our ability to perceive it accurately, and this
    MeSH term(s) Animals ; Dogs ; Human Body ; Motion ; Reaction Time ; Recognition, Psychology
    Language English
    Publishing date 2021-05-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 219170-2
    ISSN 1747-0226 ; 0033-555X ; 1747-0218
    ISSN (online) 1747-0226
    ISSN 0033-555X ; 1747-0218
    DOI 10.1177/17470218211019673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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