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  1. Article ; Online: Revisiting old friends: updates on the role of two-component signaling systems in

    Alejandro-Navarreto, Xiomarie / Freitag, Nancy E

    Infection and immunity

    2024  Volume 92, Issue 4, Page(s) e0034523

    Abstract: ... Listeria ... ...

    Abstract Listeria monocytogenes
    MeSH term(s) Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Listeria monocytogenes/genetics ; Mammals ; Signal Transduction
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/iai.00345-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Crossing the Barrier: A Comparative Study of

    Eallonardo, Samuel J / Freitag, Nancy E

    Cells

    2023  Volume 13, Issue 1

    Abstract: Vertically transmitted infections are a significant cause of fetal morbidity and mortality during pregnancy and pose substantial risks to fetal development. These infections are primarily transmitted to the fetus through two routes: (1) direct invasion ... ...

    Abstract Vertically transmitted infections are a significant cause of fetal morbidity and mortality during pregnancy and pose substantial risks to fetal development. These infections are primarily transmitted to the fetus through two routes: (1) direct invasion and crossing the placenta which separates maternal and fetal circulation, or (2) ascending the maternal genitourinary tact and entering the uterus. Only two bacterial species are commonly found to cross the placenta and infect the fetus:
    MeSH term(s) Pregnancy ; Humans ; Animals ; Female ; Treponema pallidum ; Placenta ; Listeria monocytogenes ; Treponema ; Mammals
    Language English
    Publishing date 2023-12-31
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells13010088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Two Permeases Associated with the Multifunctional CtaP Cysteine Transport System in Listeria monocytogenes Play Distinct Roles in Pathogenesis.

    Vaval Taylor, Diandra M / Xayarath, Bobbi / Freitag, Nancy E

    Microbiology spectrum

    2023  Volume 11, Issue 3, Page(s) e0331722

    Abstract: The soil-dwelling bacterium Listeria monocytogenes survives a multitude of conditions when residing in the outside environment and as a pathogen within host cells. Key to survival within the infected mammalian host is the expression of bacterial gene ... ...

    Abstract The soil-dwelling bacterium Listeria monocytogenes survives a multitude of conditions when residing in the outside environment and as a pathogen within host cells. Key to survival within the infected mammalian host is the expression of bacterial gene products necessary for nutrient acquisition. Similar to many bacteria, L. monocytogenes uses peptide import to acquire amino acids. Peptide transport systems play an important role in nutrient uptake as well as in additional functions that include bacterial quorum sensing and signal transduction, recycling of peptidoglycan fragments, adherence to eukaryotic cells, and alterations in antibiotic susceptibility. It has been previously described that CtaP, encoded by
    MeSH term(s) Animals ; Mice ; Listeria monocytogenes/genetics ; Cysteine/metabolism ; Virulence ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Virulence Factors/genetics ; Bacterial Proteins/metabolism ; Disease Models, Animal ; Gene Expression Regulation, Bacterial ; Mammals
    Chemical Substances Cysteine (K848JZ4886) ; Membrane Transport Proteins ; Virulence Factors ; Bacterial Proteins
    Language English
    Publishing date 2023-05-18
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03317-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Identification of Listeria monocytogenes Genes Contributing to Oxidative Stress Resistance under Conditions Relevant to Host Infection.

    Mains, David R / Eallonardo, Samuel J / Freitag, Nancy E

    Infection and immunity

    2021  Volume 89, Issue 4

    Abstract: The Gram-positive ... ...

    Abstract The Gram-positive bacterium
    MeSH term(s) Animals ; Bacterial Proteins/genetics ; Disease Models, Animal ; Female ; Host-Pathogen Interactions ; Hydrogen Peroxide/metabolism ; Hydrogen Peroxide/pharmacology ; Listeria monocytogenes/drug effects ; Listeria monocytogenes/genetics ; Listeria monocytogenes/pathogenicity ; Listeriosis/metabolism ; Listeriosis/microbiology ; Mice ; Mutagenesis, Insertional ; Organ Specificity ; Oxidative Stress ; Virulence Factors/genetics
    Chemical Substances Bacterial Proteins ; Virulence Factors ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2021-03-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00700-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The electrifying energy of gut microbes.

    Cahoon, Laty A / Freitag, Nancy E

    Nature

    2018  Volume 562, Issue 7725, Page(s) 43–44

    MeSH term(s) Electrons ; Flavins ; Gastrointestinal Tract ; Gram-Positive Bacteria
    Chemical Substances Flavins
    Language English
    Publishing date 2018-10-01
    Publishing country England
    Document type News ; Comment
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-018-06180-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Regulation of

    Johansson, Jörgen / Freitag, Nancy E

    Microbiology spectrum

    2019  Volume 7, Issue 4

    Abstract: Whereas obligate human and animal bacterial pathogens may be able to depend upon the warmth and relative stability of their chosen replication niche, environmental bacteria such ... ...

    Abstract Whereas obligate human and animal bacterial pathogens may be able to depend upon the warmth and relative stability of their chosen replication niche, environmental bacteria such as
    MeSH term(s) Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Humans ; Immunity, Innate ; Listeria monocytogenes/genetics ; Listeria monocytogenes/metabolism ; Listeria monocytogenes/pathogenicity ; Listeriosis/immunology ; Listeriosis/microbiology ; Osmolar Concentration ; Virulence
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2019-09-09
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2165-0497
    ISSN (online) 2165-0497
    DOI 10.1128/microbiolspec.GPP3-0064-2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Vertical Transmission of

    Lamond, Nicole M / Freitag, Nancy E

    Pathogens (Basel, Switzerland)

    2018  Volume 7, Issue 2

    Abstract: Protection of the developing fetus from pathogens is one of the many critical roles of the placenta. ...

    Abstract Protection of the developing fetus from pathogens is one of the many critical roles of the placenta.
    Language English
    Publishing date 2018-05-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens7020052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Bacillus subtilis

    Ryan-Payseur, Bridgett K / Freitag, Nancy E

    mBio

    2018  Volume 9, Issue 6

    Abstract: ... Bacillus ... ...

    Abstract Bacillus subtilis
    MeSH term(s) Bacillus subtilis ; Bacterial Proteins/genetics ; Biofilms ; Gene Expression Regulation, Bacterial ; Mutation
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2018-11-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mBio.02339-18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Propofol Sedation Exacerbates Kidney Pathology and Dissemination of Bacteria during Staphylococcus aureus Bloodstream Infections.

    Visvabharathy, Lavanya / Freitag, Nancy E

    Infection and immunity

    2017  Volume 85, Issue 7

    Abstract: Methicillin- ... ...

    Abstract Methicillin-resistant
    MeSH term(s) Animals ; Bacteremia/pathology ; Bacterial Load ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Disease Models, Animal ; Disease Susceptibility/chemically induced ; Female ; Hypnotics and Sedatives/adverse effects ; Kidney Diseases/chemically induced ; Kidney Diseases/pathology ; Macrophages/drug effects ; Macrophages/immunology ; Methicillin-Resistant Staphylococcus aureus/isolation & purification ; Mice ; Neutrophils/drug effects ; Neutrophils/immunology ; Propofol/adverse effects ; Staphylococcal Infections/pathology
    Chemical Substances Hypnotics and Sedatives ; Propofol (YI7VU623SF)
    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00097-17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: When being alone is enough: noncanonical functions of canonical bacterial quorum-sensing systems.

    Xayarath, Bobbi / Freitag, Nancy E

    Future microbiology

    2016  Volume 11, Page(s) 1447–1459

    Abstract: A number of bacterial pathogens are capable of detecting the presence of other bacteria located within their surrounding niche through a process of bacterial signaling and cell-to-cell communication commonly referred to as quorum sensing (QS). QS systems ...

    Abstract A number of bacterial pathogens are capable of detecting the presence of other bacteria located within their surrounding niche through a process of bacterial signaling and cell-to-cell communication commonly referred to as quorum sensing (QS). QS systems are commonly now described in the context of collective behaviors exhibited by groups of bacteria coordinating diverse arrays of physiological functions to enhance survival of the community. However, QS systems have also been implicated in a variety of processes distinct from the measure of bacterial cell density. This review will highlight noncanonical adaptations of canonical QS systems that have evolved to enable bacteria to detect nonself individuals within a population or to detect occupation of confined spaces.
    MeSH term(s) Bacteria/metabolism ; Bacterial Physiological Phenomena ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Cell Communication/physiology ; Cell Count ; Enterococcus/genetics ; Enterococcus/metabolism ; Gene Expression Regulation, Bacterial ; Host-Parasite Interactions/physiology ; Listeria/genetics ; Listeria/metabolism ; Quorum Sensing/physiology ; Signal Transduction/physiology ; Staphylococcus/genetics ; Staphylococcus/metabolism ; Vacuoles/microbiology
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2016-10
    Publishing country England
    Document type Journal Article ; Review
    ISSN 1746-0921
    ISSN (online) 1746-0921
    DOI 10.2217/fmb-2016-0066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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