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  1. Article ; Online: Psychometric properties of the Kidney Disease Quality of Life short form 36 (KDQOL-36) scale for the assessment of quality of life in Colombian patients with chronic kidney disease on dialysis.

    Valderrama-Rios, Martha Carolina / Sánchez, Ricardo / Sanabria, Mauricio

    International urology and nephrology

    2024  

    Abstract: Purpose: Considering the importance of incorporating quality of life (QoL) construct during the health care of patients with stage 5 chronic kidney disease (CKD) on dialysis, it is necessary to have evidence on the clinimetric properties of the ... ...

    Abstract Purpose: Considering the importance of incorporating quality of life (QoL) construct during the health care of patients with stage 5 chronic kidney disease (CKD) on dialysis, it is necessary to have evidence on the clinimetric properties of the instruments used for its measurement. This study aimed to establish the clinimetric properties of the Kidney Disease Quality of Life Short Form 36 (KDQOL-36) scale in patients with stage 5 CKD on dialysis in Colombia.
    Methods: A scale validation study was conducted using the classical test theory methodology. The statistical analysis included exploratory factor analysis (EFA) and confirmatory (CFA) techniques performed on two independent subsamples; concurrent criterion validity assessments; internal consistency using four different coefficients; test-retest reliability; and sensitivity to change using mixed model for repeated measures.
    Results: The KDQOL-36 scale was applied to 506 patients with a diagnosis of stage 5 CKD on dialysis, attended in five renal units in Colombia. The EFA endorsed the three-factor structure of the scale, and the CFA showed an adequate fit of both the original and empirical models. Spearman's correlation coefficient values ≥0.50 were found between the domains of the CKD-specific core of the KDQOL-36 scale and the KDQ. Cronbach's alpha, McDonald's omega, Greatest lower bound (GLB), and Guttman's lambda coefficients were ≥0.89, indicating a high degree of consistency. A high level of concordance correlation was found between the two moments of application of the instrument, with values for Lin's concordance correlation coefficient ≥0.7. The application of the instrument after experiencing an event that could modify the quality of life showed statistically significant differences in the scores obtained.
    Conclusion: The KDQOL-36 scale is an adequate instrument for measuring QoL in Colombian patients with stage 5 CKD on dialysis.
    Language English
    Publishing date 2024-02-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-024-03940-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article: Interventions to Improve Antibiotic Use in Hospitals with Different Levels of Complexity in Colombia: Findings from a Before-and-After Study and Suggestions for the Future.

    Valderrama-Rios, Martha Carolina / Álvarez-Moreno, Carlos Arturo / Cortes, Jorge Alberto

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: Background: In the collaborative efforts to control bacterial antimicrobial resistance (AMR), the challenge for many low- and middle-income countries currently lies in the adequate design and successful implementation and operation of different ... ...

    Abstract Background: In the collaborative efforts to control bacterial antimicrobial resistance (AMR), the challenge for many low- and middle-income countries currently lies in the adequate design and successful implementation and operation of different strategies aimed at improving antibiotic use during hospital care. This study aims to provide data on these different strategies in three hospitals with different levels of complexity and geographic locations in Colombia.
    Methods: This before-and-after study describes and analyzes the development and implementation of clinical practice guidelines (CPGs), continuing education courses, quick consultation tools, and antimicrobial stewardship programs (ASPs) with the use of telemedicine. This includes measuring indicators in the ASP framework such as adherence to CPGs and antibiotic consumption.
    Results: We used five CPGs developed in the Colombian context. We designed and developed a Massive Open Online Course (MOOC) and a mobile application (app) as strategies for dissemination and implementation. The ASP was designed and implemented according to each institution's level of complexity. In the three hospitals, a progressive increase in adherence to the antibiotic recommendations proposed in the CPGs was observed, and there was a lower use of antibiotics with the ASPs, both in the general wards and ICUs.
    Conclusions: We concluded that in medium-complexity hospitals located in small rural cities, successful development of ASPs is possible when they are well-planned, implemented, and supported by the organization. It is necessary that Colombia and other Latin American countries continue activities that reduce AMR by designing, implementing, and improving these interventions throughout the national territory.
    Language English
    Publishing date 2023-05-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12050867
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  3. Book ; Online: Víctimas de guerra y derechos humanos

    Clavijo, Isabel Cristina / Vélez Rojas, Jherica Leandra / Giraldo Montoya, Elizabeth Cristina / Montoya Ortega, León Fernando / Múnera Zapata, Sara / Suárez Barrientos, David Alexander / Arenas Valderrama, Yudi Tatiana / Fontalvo Caro, Luisa Fernanda / Buriticá Amaya, Sebastián / Moncada Deosa, Carolina / Gaviria Sepúlveda, María Noemí / Aguirre González, Alejandra / Duque Gómez, Gloria Jacinta / Molina Molina, Laura María / Villa Zapata, Yesica / Zapata García, Nadia Viviana / Millán Otero, Katy Luz / Vanegas Amaya, Carlos Mauricio / Cortez, Néstor /
    Amigó, Universidad Católica Luis

    2022  

    Keywords Society & social sciences ; Psychology ; Social psychology ; Human rights
    Language 0|s
    Size 1 electronic resource (107 pages)
    Publisher Universidad Católica Luis Amigó
    Publishing place Medellín, Antioquia, Colombia
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021608957
    ISBN 9789588943794 ; 9588943795
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Comment on: Gaps and barriers in the implementation and functioning of antimicrobial stewardship programmes: results from an educational and behavioural mixed methods needs assessment in France, the United States, Mexico and India.

    Valderrama-Rios, Martha Carolina / Nocua-Báez, Laura Cristina / Álvarez-Moreno, Carlos Arturo / Cortes, Jorge Alberto

    JAC-antimicrobial resistance

    2023  Volume 5, Issue 2, Page(s) dlad050

    Language English
    Publishing date 2023-04-28
    Publishing country England
    Document type Journal Article
    ISSN 2632-1823
    ISSN (online) 2632-1823
    DOI 10.1093/jacamr/dlad050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Formación Ciudadana en Carreras de Pedagogía

    Sebastián Torres Valderrama / Carolina Aparicio Molina

    Sophia Austral, Vol

    Estudio de Caso en una Institución de Educación Superior del sur de Chile

    2022  Volume 28

    Abstract: Las investigaciones en Formación Inicial Docente son diversas por la amplitud aspectos que abarca. En este sentido, el presente artículo busca analizar las percepciones y características sobre las Actividades Curriculares relacionadas con Formación ... ...

    Abstract Las investigaciones en Formación Inicial Docente son diversas por la amplitud aspectos que abarca. En este sentido, el presente artículo busca analizar las percepciones y características sobre las Actividades Curriculares relacionadas con Formación Ciudadana, por medio de entrevistas semiestructuradas, en tres carreras de pedagogía de una universidad de la Región del Biobío. De acuerdo con el propósito, se utilizó un enfoque Cualitativo con método de Estudio de Caso Múltiple, en la investigación participaron estudiantes y docentes de las carreras seleccionadas. Los resultados demuestran que, las Actividades Curriculares se caracterizan por ser teórico-práctico, lo permite que el futuro profesorado pueda acercarse a su trabajo en aula. En relación con las estrategias implementadas, queda en evidencia que se orientan hacia metodologías activas; para desarrollar diversos conocimientos, habilidades y actitudes. Se puede concluir, que es necesario destinar mayor cantidad de tiempo a estas Actividades Curriculares para profundizar en contenidos y didácticas de la Formación Ciudadana.
    Keywords Ciudadanía ; Formación Inicial Docente ; Formación Ciudadana ; Ethnology. Social and cultural anthropology ; GN301-674 ; Special aspects of education ; LC8-6691
    Language Spanish
    Publishing date 2022-12-01T00:00:00Z
    Publisher Universidad de Magallanes
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Alectinib for treating patients with metastatic

    Samacá-Samacá, Daniel / Prieto-Pinto, Laura / Peréz, Andrés Yepes / Valderrama, Carolina / Hernández, Fabián

    Lung cancer management

    2023  Volume 12, Issue 2, Page(s) LMT59

    Abstract: Aim: To compare the efficacy and safety of alectinib with other ALK inhibitors in treating patients with metastatic or locally advanced : Methods: A systematic literature review was conducted up to November 2021. Network meta-analyses were performed ... ...

    Abstract Aim: To compare the efficacy and safety of alectinib with other ALK inhibitors in treating patients with metastatic or locally advanced
    Methods: A systematic literature review was conducted up to November 2021. Network meta-analyses were performed using the frequentist method (random effects). GRADE evidence profile was conducted.
    Results: 13 RCTs were selected. For overall survival, alectinib was found to reduce the risk of death compared with crizotinib. In progression-free survival, alectinib reduced the risk of death or progression compared with crizotinib and ceritinib. Subgroup analysis by brain metastasis at baseline showed the superiority of alectinib over crizotinib and a similar effect compared with second-and third-generation inhibitors. Alectinib showed a good safety profile compared with the other ALK inhibitors.
    Language English
    Publishing date 2023-05-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2669715-4
    ISSN 1758-1974 ; 1758-1966
    ISSN (online) 1758-1974
    ISSN 1758-1966
    DOI 10.2217/lmt-2022-0018
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  7. Article ; Online: Efficacy and safety of preemptive therapy for cytomegalovirus end-organ disease in people living with HIV: a systematic review and meta-analysis.

    Díaz-Brochero, Cándida / Nocua-Báez, Laura Cristina / Valderrama-Rios, Martha Carolina / Cortés, Jorge Alberto

    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

    2023  Volume 27, Issue 5, Page(s) 102805

    Abstract: Introduction: Cytomegalovirus end-organ-disease (CMV EOD) is still a major cause of debilitating illness in people living with HIV, especially in developing countries.: Objective: To evaluate the efficacy and safety of preemptive therapy against CMV ... ...

    Abstract Introduction: Cytomegalovirus end-organ-disease (CMV EOD) is still a major cause of debilitating illness in people living with HIV, especially in developing countries.
    Objective: To evaluate the efficacy and safety of preemptive therapy against CMV EOD in HIV-positive adults with CMV viremia.
    Methods: Systematic review of clinical trials by searching electronic databases and clinical trial registries, screening and selection of references, data extraction and assessment of risk of bias. The results were presented in a narrative synthesis. Aggregated analyzes for dichotomous outcomes were reported as odds ratios with 95 % Confidence Intervals.
    Results: Four RTC were included. A reduction in the risk of CMV EOD with preemptive therapy was found OR=0.49 (95 % CI 0.31‒0.76). We did not identify significant differences for all-cause mortality, adverse events, and withdrawal of the therapy secondary to adverse events.
    Conclusions: Preemptive therapy could be a potential option for preventing CMV EOD in people living with HIV.
    MeSH term(s) Adult ; Humans ; Antiviral Agents/therapeutic use ; Cytomegalovirus ; Cytomegalovirus Infections/prevention & control ; Cytomegalovirus Infections/diagnosis ; Viremia/complications ; Viremia/drug therapy ; Viremia/prevention & control ; HIV Infections/complications ; HIV Infections/drug therapy
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-09-27
    Publishing country Brazil
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2041400-6
    ISSN 1678-4391 ; 1413-8670
    ISSN (online) 1678-4391
    ISSN 1413-8670
    DOI 10.1016/j.bjid.2023.102805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5633: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article ; Online: Modeling the Potential Distribution of the Malaria Vector

    Valderrama, Lara / Ayala, Salvador / Reyes, Carolina / González, Christian R

    Frontiers in public health

    2021  Volume 9, Page(s) 611152

    Abstract: The extreme north of Chile presents a subtropical climate permissive of the establishment of potential disease vectors. ...

    Abstract The extreme north of Chile presents a subtropical climate permissive of the establishment of potential disease vectors.
    MeSH term(s) Animals ; Anopheles ; Argentina ; Chile ; Disease Vectors ; Humans ; Malaria ; Mosquito Vectors
    Language English
    Publishing date 2021-05-11
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.611152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: El rol de la identidad lectora del profesor en la mediación literaria

    Guillermo Valderrama / Felipe Gajardo Gajardo / Nicole Zuñiga Marín / Carolina Merino Risopatron

    Sophia Austral, Vol

    2023  Volume 28

    Abstract: Estudiar el rol del profesor en la educación literaria se ha vuelto relevante en los últimos años en el campo de la Didáctica de la lengua y la literatura, sin embargo, en Chile el tema no se ha explorado en profundidad. El objetivo de la investigación ... ...

    Abstract Estudiar el rol del profesor en la educación literaria se ha vuelto relevante en los últimos años en el campo de la Didáctica de la lengua y la literatura, sin embargo, en Chile el tema no se ha explorado en profundidad. El objetivo de la investigación fue caracterizar los perfiles lectores y prácticas didácticas de un grupo de docentes de Lengua y Literatura que participan en programas de fomento lector, a partir de sus creencias acerca de la educación literaria. Para ello se utilizó́ un diseño mixto, integrando en los distintos momentos de la indagatoria los enfoques cuantitativo y cualitativo con el propósito de alcanzar una visión más completa del fenómeno de investigación. La muestra contó con 14 profesores, algunos participantes del programa “Diálogos en Movimiento”, docentes que se desempeñan en establecimientos rurales y otros en escuelas y liceos de la región del Maule (Chile). Todos ellos respondieron un cuestionario, mientras que a 3 docentes se les aplicó además una entrevista. Los perfiles obtenidos los muestran como lectores poco frecuentes de literatura, cuya identidad lectora está construida principalmente a partir de su proyección como mediadores en el aula que buscan la construcción de hábitos lectores en sus estudiantes antes que procesos interpretativos con complejidad progresiva. Lo anterior permite concluir que, si bien no es posible asegurar una relación de causalidad directa entre el perfil de un docente y su ejercicio profesional, el propio comportamiento como lector tiene relación con los objetivos que se privilegian en la educación literaria ofrecida.
    Keywords Educación literaria ; Perfil lector ; Creencias ; Mediación lectora ; Ethnology. Social and cultural anthropology ; GN301-674 ; Special aspects of education ; LC8-6691
    Language Spanish
    Publishing date 2023-01-01T00:00:00Z
    Publisher Universidad de Magallanes
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: First-generation cephalosporins for the treatment of complicated upper urinary tract infection in adults: A systematic literature review.

    Díaz-Brochero, Cándida / Valderrama-Rios, Martha Carolina / Nocua-Báez, Laura Cristina / Cortés, Jorge Alberto

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2022  Volume 116, Page(s) 403–410

    Abstract: Introduction: Complicated upper urinary tract infection (UTI) is a significant cause of infectious morbidity and in-hospital antibiotic therapy. However, the use of first-generation cephalosporins in this scenario is not clearly defined.: Objective: ... ...

    Abstract Introduction: Complicated upper urinary tract infection (UTI) is a significant cause of infectious morbidity and in-hospital antibiotic therapy. However, the use of first-generation cephalosporins in this scenario is not clearly defined.
    Objective: To evaluate the efficacy and safety of first-generation cephalosporins for community-acquired complicated upper UTI in adults requiring hospital care.
    Methods: Systematic review by searching electronic databases (MEDLINE, Embase, CENTRAL) and trials registers. The articles were then screened and the references were selected, data was extracted, and risk of bias assessment was conducted. The results are presented in a narrative synthesis.
    Results: Seven randomized clinical trials were included. We did not identify statistically significant differences when comparing first-generation cephalosporins with other antimicrobials for outcomes of clinical cure, length of hospital-stay, and reinfection. However, a lower probability of microbiological cure and a higher probability of relapse was identified in the first-generation cephalosporin group in 3 of 7 studies and in 2 of 5 studies, respectively. No serious adverse effects were reported.
    Conclusions: First-generation cephalosporins could be a potential therapy in this setting, nevertheless the low quality of evidence for analyzed outcomes should be considered because of the limitations of the risk of bias assessment and its inaccuracy. It is essential to carry out comparative studies in which the benefits and harms of these antibiotics are evaluated.
    MeSH term(s) Adult ; Anti-Bacterial Agents/adverse effects ; Cephalosporins/adverse effects ; Humans ; Urinary Tract Infections/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Cephalosporins
    Language English
    Publishing date 2022-01-10
    Publishing country Canada
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2021.12.363
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