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  1. Article ; Online: The recent burden of dengue infection in Bangladesh

    Nurshad Ali

    Journal of Infection and Public Health, Vol 17, Iss 2, Pp 226-

    A serious public health issue

    2024  Volume 228

    Abstract: Dengue is a rapidly increasing vector-borne disease with a high burden in South and Southeast Asia. This article presents an overview of the current dengue situation in Bangladesh, highlighting the critical public health challenges caused by this ... ...

    Abstract Dengue is a rapidly increasing vector-borne disease with a high burden in South and Southeast Asia. This article presents an overview of the current dengue situation in Bangladesh, highlighting the critical public health challenges caused by this infectious disease. Between January and September 2023, a total of 203406 people were infected, and 989 people died, with a case fatality rate of 0.49%. Of these, 96.1% of infections and 95.2% of deaths occurred between July and September. Both infection and mortality rates showed a significant and positive correlation with population density and air quality index. Other environmental and socioeconomic factors may influence the burden of dengue infection. These include temperature, rainfall, humidity, unplanned urbanization, and water storage and waste management practices. To reduce transmission and mortality rates, it is urgent to prioritize early treatment of dengue cases and take measures to address the risk factors associated with dengue infection in the country.
    Keywords Dengue ; Infection ; Death ; Bangladesh ; Public health ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Subject code 630
    Language English
    Publishing date 2024-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The recent burden of dengue infection in Bangladesh: A serious public health issue.

    Ali, Nurshad

    Journal of infection and public health

    2023  Volume 17, Issue 2, Page(s) 226–228

    Abstract: Dengue is a rapidly increasing vector-borne disease with a high burden in South and Southeast Asia. This article presents an overview of the current dengue situation in Bangladesh, highlighting the critical public health challenges caused by this ... ...

    Abstract Dengue is a rapidly increasing vector-borne disease with a high burden in South and Southeast Asia. This article presents an overview of the current dengue situation in Bangladesh, highlighting the critical public health challenges caused by this infectious disease. Between January and September 2023, a total of 203406 people were infected, and 989 people died, with a case fatality rate of 0.49%. Of these, 96.1% of infections and 95.2% of deaths occurred between July and September. Both infection and mortality rates showed a significant and positive correlation with population density and air quality index. Other environmental and socioeconomic factors may influence the burden of dengue infection. These include temperature, rainfall, humidity, unplanned urbanization, and water storage and waste management practices. To reduce transmission and mortality rates, it is urgent to prioritize early treatment of dengue cases and take measures to address the risk factors associated with dengue infection in the country.
    MeSH term(s) Humans ; Public Health ; Dengue/epidemiology ; Bangladesh/epidemiology ; Humidity ; Temperature
    Language English
    Publishing date 2023-12-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2023.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Elevated level of C-reactive protein may be an early marker to predict risk for severity of COVID-19.

    Ali, Nurshad

    Journal of medical virology

    2020  Volume 92, Issue 11, Page(s) 2409–2411

    MeSH term(s) Biomarkers/blood ; C-Reactive Protein/analysis ; COVID-19/blood ; COVID-19/diagnosis ; Cytokines/immunology ; Humans ; Inflammation/complications ; Prognosis ; Severity of Illness Index
    Chemical Substances Biomarkers ; Cytokines ; C-Reactive Protein (9007-41-4)
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26097
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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Relationship Between COVID-19 Infection and Liver Injury

    Nurshad Ali

    Frontiers in Medicine, Vol

    A Review of Recent Data

    2020  Volume 7

    Abstract: The COVID-19 outbreak is a great threat to public health worldwide. Lung injury is the main outcome of COVID-19 infection; however, damage can occur in other organs including the liver. Currently, limited data are available that link underlying liver ... ...

    Abstract The COVID-19 outbreak is a great threat to public health worldwide. Lung injury is the main outcome of COVID-19 infection; however, damage can occur in other organs including the liver. Currently, limited data are available that link underlying liver injury with the severe SARS-CoV-2 infection. This review summarizes the available data on liver test abnormalities in COVID-19 patients; critically evaluates the possible causes of liver injury and provides recommendations for clinicians. In laboratory tests, serum levels of liver test markers notably transaminase, gamma-glutamyl transferase and total bilirubin were significantly higher in severe patients with COVID-19 infection. The use of certain drugs especially lopinavir and ritonavir showed an association with the progression of liver damage in severe cases. Available data suggest that liver injury in COVID-19 patients may result from direct effect by the virus, immune-mediated inflammation or drug-induced toxicity. Some studies demonstrated that COVID-19 patients with pre-existing liver disease are at higher risk for hospitalizations and mortality. Therefore, the impact of pre-existing liver disease on treatment and clinical outcomes of COVID-19 should be determined. Large-scale clinical studies are needed to identify the causes of liver injury in patients with COVID-19 infection.
    Keywords SARS-CoV-2 ; COVID-19 ; liver enzymes ; liver disease ; liver injury ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Role of vitamin D in preventing of COVID-19 infection, progression and severity

    Nurshad Ali

    Journal of Infection and Public Health, Vol 13, Iss 10, Pp 1373-

    2020  Volume 1380

    Abstract: The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately ... ...

    Abstract The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles of vitamin D in reducing the risk of COVID-19 and other acute respiratory tract infections and severity. Moreover, this study determined the correlation of vitamin D levels with COVID-19 cases and deaths in 20 European countries as of 20 May 2020. A significant negative correlation (p = 0.033) has been observed between mean vitamin D levels and COVID-19 cases per one million population in European countries. However, the correlation of vitamin D with COVID-19 deaths of these countries was not significant. Some retrospective studies demonstrated a correlation between vitamin D status and COVID-19 severity and mortality, while other studies did not find the correlation when confounding variables are adjusted. Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75–125 nmol/L). In conclusion, there is not enough evidence on the association between vitamin D levels and COVID-19 severity and mortality. Therefore, randomized control trials and cohort studies are necessary to test this hypothesis.
    Keywords COVID-19 ; SARS-CoV-2 ; Infections ; Vitamin D ; Vitamin D supplementation ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270 ; covid19
    Subject code 610
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Is SARS-CoV-2 associated with liver dysfunction in COVID-19 patients?

    Ali, Nurshad

    Clinics and research in hepatology and gastroenterology

    2020  Volume 44, Issue 4, Page(s) e84–e86

    MeSH term(s) Alanine Transaminase/blood ; Angiotensin-Converting Enzyme 2 ; Antiviral Agents/adverse effects ; Aspartate Aminotransferases/blood ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Humans ; Liver Diseases/enzymology ; Liver Diseases/etiology ; Pandemics ; Peptidyl-Dipeptidase A ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Risk Factors ; SARS-CoV-2 ; gamma-Glutamyltransferase/blood
    Chemical Substances Antiviral Agents ; gamma-Glutamyltransferase (EC 2.3.2.2) ; Aspartate Aminotransferases (EC 2.6.1.1) ; Alanine Transaminase (EC 2.6.1.2) ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-05-21
    Publishing country France
    Document type Letter
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2020.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Relationship Between COVID-19 Infection and Liver Injury: A Review of Recent Data.

    Ali, Nurshad

    Frontiers in medicine

    2020  Volume 7, Page(s) 458

    Abstract: The COVID-19 outbreak is a great threat to public health worldwide. Lung injury is the main outcome of COVID-19 infection; however, damage can occur in other organs including the liver. Currently, limited data are available that link underlying liver ... ...

    Abstract The COVID-19 outbreak is a great threat to public health worldwide. Lung injury is the main outcome of COVID-19 infection; however, damage can occur in other organs including the liver. Currently, limited data are available that link underlying liver injury with the severe SARS-CoV-2 infection. This review summarizes the available data on liver test abnormalities in COVID-19 patients; critically evaluates the possible causes of liver injury and provides recommendations for clinicians. In laboratory tests, serum levels of liver test markers notably transaminase, gamma-glutamyl transferase and total bilirubin were significantly higher in severe patients with COVID-19 infection. The use of certain drugs especially lopinavir and ritonavir showed an association with the progression of liver damage in severe cases. Available data suggest that liver injury in COVID-19 patients may result from direct effect by the virus, immune-mediated inflammation or drug-induced toxicity. Some studies demonstrated that COVID-19 patients with pre-existing liver disease are at higher risk for hospitalizations and mortality. Therefore, the impact of pre-existing liver disease on treatment and clinical outcomes of COVID-19 should be determined. Large-scale clinical studies are needed to identify the causes of liver injury in patients with COVID-19 infection.
    Keywords covid19
    Language English
    Publishing date 2020-07-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2020.00458
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  8. Article ; Online: Role of vitamin D in preventing of COVID-19 infection, progression and severity.

    Ali, Nurshad

    Journal of infection and public health

    2020  Volume 13, Issue 10, Page(s) 1373–1380

    Abstract: The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately ... ...

    Abstract The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles of vitamin D in reducing the risk of COVID-19 and other acute respiratory tract infections and severity. Moreover, this study determined the correlation of vitamin D levels with COVID-19 cases and deaths in 20 European countries as of 20 May 2020. A significant negative correlation (p=0.033) has been observed between mean vitamin D levels and COVID-19 cases per one million population in European countries. However, the correlation of vitamin D with COVID-19 deaths of these countries was not significant. Some retrospective studies demonstrated a correlation between vitamin D status and COVID-19 severity and mortality, while other studies did not find the correlation when confounding variables are adjusted. Several studies demonstrated the role of vitamin D in reducing the risk of acute viral respiratory tract infections and pneumonia. These include direct inhibition with viral replication or with anti-inflammatory or immunomodulatory ways. In the meta-analysis, vitamin D supplementation has been shown as safe and effective against acute respiratory tract infections. Thus, people who are at higher risk of vitamin D deficiency during this global pandemic should consider taking vitamin D supplements to maintain the circulating 25(OH)D in the optimal levels (75-125nmol/L). In conclusion, there is not enough evidence on the association between vitamin D levels and COVID-19 severity and mortality. Therefore, randomized control trials and cohort studies are necessary to test this hypothesis.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/blood ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Dietary Supplements ; Disease Progression ; Europe/epidemiology ; Humans ; Pandemics/prevention & control ; Patient Acuity ; Pneumonia, Viral/blood ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; Vitamin D/analogs & derivatives ; Vitamin D/blood ; Vitamin D/pharmacology ; Vitamin D/therapeutic use ; Vitamins/pharmacology ; Vitamins/therapeutic use
    Chemical Substances Vitamins ; Vitamin D (1406-16-2) ; 25-hydroxyvitamin D (A288AR3C9H)
    Keywords covid19
    Language English
    Publishing date 2020-06-20
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2020.06.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Aflatoxin M

    Ali, Nurshad / Habib, Ahsan / Mahmud, Firoz / Tuba, Humaira Rashid / Degen, Gisela H

    Toxins

    2024  Volume 16, Issue 1

    Abstract: Presence of aflatoxin ... ...

    Abstract Presence of aflatoxin B
    MeSH term(s) Humans ; Aflatoxin M1 ; Pilot Projects ; Bangladesh ; Crops, Agricultural ; Biomarkers
    Chemical Substances Aflatoxin M1 (6795-23-9) ; Biomarkers
    Language English
    Publishing date 2024-01-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins16010045
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