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  1. Article ; Online: Spatiotemporal evolution of sea ice and its teleconnections with large-scale climate indices over Antarctica.

    Swathi, M / Kumar, Avinash / Mohan, Rahul

    Marine pollution bulletin

    2023  Volume 188, Page(s) 114634

    Abstract: Sea ice variability patterns are highly influenced by several large-scale ocean-atmospheric oscillations. We analysed both statistical and wavelet coherence methods to examine sea ice's interannual and interdecadal variability. During the past 42-year, ... ...

    Abstract Sea ice variability patterns are highly influenced by several large-scale ocean-atmospheric oscillations. We analysed both statistical and wavelet coherence methods to examine sea ice's interannual and interdecadal variability. During the past 42-year, the total Southern Ocean sea ice extent (SIE) has expanded, while the Amundsen-Bellingshausen Sea SIE has decreased. A wavelet coherence analysis (WCA) of El Niño Southern Oscillation (ENSO) and the SIE in various sectors revealed an out-of-phase correlation between the Indian Ocean and the Ross Sea. There are significant out-of-phase correlations between sea ice variability and Indian Ocean Dipole (IOD) on an interannual scale. A consistent phase relationship was seen between SIE and Southern Annular Mode (SAM) over the past decade, with in-phase relationships advancing to out-of-phase relationships. The Interdecadal Pacific Oscillation (IPO) shifted from positive to negative after the 1990s. In recent years, SAM has had a stronger impact on sea ice variability than ENSO.
    MeSH term(s) Ice Cover ; Antarctic Regions ; El Nino-Southern Oscillation ; Indian Ocean
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2023.114634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Combination-type periprosthetic tibial fracture: Felix type (II+IV)A.

    Pai, Satvik N / Kumar, Mohan M

    BMJ case reports

    2023  Volume 16, Issue 2

    Abstract: Tibial periprosthetic fractures are rare but present a complicated problem for orthopaedic surgeons. Literature in relation to combination-type periprosthetic fractures is extremely scarce, and there is limited guidance available on its treatment. We ... ...

    Abstract Tibial periprosthetic fractures are rare but present a complicated problem for orthopaedic surgeons. Literature in relation to combination-type periprosthetic fractures is extremely scarce, and there is limited guidance available on its treatment. We report the case of a woman in her 60s, whose radiographs revealed a periprosthetic fracture of the tibia, which was a Felix type (II+IV)A fracture. The tibial tuberosity fragment was fixed with a cannulated cancellous screw. The fracture adjacent to the stem was managed conservatively as the prosthesis was stable. Follow-up radiographs revealed both fractures to have healed completely by 12 weeks. The patient returned to preinjury functional levels by 4 months. Our demonstrated treatment of a Felix type II+IV periprosthetic fracture could be a viable treatment option for such fractures.
    MeSH term(s) Female ; Humans ; Tibia/surgery ; Periprosthetic Fractures/surgery ; Arthroplasty, Replacement, Knee/adverse effects ; Tibial Fractures/surgery ; Fracture Fixation, Internal/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-252464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Inverted horn myositis ossificans circumscripta in the pelvis and bilateral adductors: an unreported shape at an unusual site.

    Pai, Satvik N / Kumar, Mohan M

    ANZ journal of surgery

    2022  Volume 92, Issue 11, Page(s) 3040–3041

    MeSH term(s) Humans ; Myositis Ossificans/diagnostic imaging ; Pelvis ; Myositis ; Abdomen
    Language English
    Publishing date 2022-01-25
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.17502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Isolated lunate dislocation.

    Pai, Satvik N / Kumar, Mohan M

    BMJ case reports

    2022  Volume 15, Issue 3

    MeSH term(s) Humans ; Joint Dislocations/diagnostic imaging ; Joint Dislocations/surgery ; Lunate Bone/diagnostic imaging ; Wrist Injuries/diagnostic imaging ; Wrist Injuries/surgery
    Language English
    Publishing date 2022-03-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-248917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Gaussian Adapted Markov Model with Overhauled Fluctuation Analysis-Based Big Data Streaming Model in Cloud.

    Ananthi, M / Gopal, Annapoorani / Ramalakshmi, K / Mohan Kumar, P

    Big data

    2023  Volume 12, Issue 1, Page(s) 1–18

    Abstract: An accurate resource usage prediction in the big data streaming applications still remains as one of the complex processes. In the existing works, various resource scaling techniques are developed for forecasting the resource usage in the big data ... ...

    Abstract An accurate resource usage prediction in the big data streaming applications still remains as one of the complex processes. In the existing works, various resource scaling techniques are developed for forecasting the resource usage in the big data streaming systems. However, the baseline streaming mechanisms limit with the issues of inefficient resource scaling, inaccurate forecasting, high latency, and running time. Therefore, the proposed work motivates to develop a new framework, named as Gaussian adapted Markov model (GAMM)-overhauled fluctuation analysis (OFA), for an efficient big data streaming in the cloud systems. The purpose of this work is to efficiently manage the time-bounded big data streaming applications with reduced error rate. In this study, the gating strategy is also used to extract the set of features for obtaining nonlinear distribution of data and fat convergence solution, used to perform the fluctuation analysis. Moreover, the layered architecture is developed for simplifying the process of resource forecasting in the streaming applications. During experimentation, the results of the proposed stream model GAMM-OFA are validated and compared by using different measures.
    MeSH term(s) Big Data ; Cloud Computing
    Language English
    Publishing date 2023-10-30
    Publishing country United States
    Document type Journal Article
    ISSN 2167-647X
    ISSN (online) 2167-647X
    DOI 10.1089/big.2023.0035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Liposclerosing myxofibrous tumour.

    Pai, Satvik N / Kumar, Mohan M

    BMJ case reports

    2021  Volume 14, Issue 8

    MeSH term(s) Femoral Neoplasms ; Fibroma ; Humans
    Language English
    Publishing date 2021-08-05
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-245487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Giant synovial chondromatosis of hip.

    Pai, Satvik N / Kumar, Mohan M

    BMJ case reports

    2022  Volume 15, Issue 1

    Abstract: Synovial chondromatosis is a rare, benign condition occurring due to metaplasia of synovium. A 65-year-old woman presented with pain in her right hip for 6 years. On examination, a swelling was palpable at the base of scarpa's triangle and her right hip ... ...

    Abstract Synovial chondromatosis is a rare, benign condition occurring due to metaplasia of synovium. A 65-year-old woman presented with pain in her right hip for 6 years. On examination, a swelling was palpable at the base of scarpa's triangle and her right hip movements were restricted. Imaging modalities showed ossified nodules in the antero-inferior aspect of the hip joint, joint effusion and arthritic changes. We diagnosed the patient to have synovial chondromatosis with secondary arthritis of the hip joint. We performed a total hip arthroplasty with simultaneous synovectomy and extraction of the osteochondral loose bodies, 5 of which were about 2×2 cm in size. We found that excessive acetabular reaming was required due to craters, the osteochondral masses formed on the acetabular surface. Histopathological analysis confirmed the diagnosis. The patient had an excellent functional outcome and no recurrence 5 years following the surgery.
    MeSH term(s) Aged ; Arthroplasty, Replacement, Hip ; Chondromatosis, Synovial/diagnostic imaging ; Chondromatosis, Synovial/surgery ; Female ; Hip Joint/diagnostic imaging ; Hip Joint/surgery ; Humans ; Joint Loose Bodies ; Synovectomy
    Language English
    Publishing date 2022-01-21
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-246039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Leveraging Lymphatic System Targeting in Systemic Lupus Erythematosus for Improved Clinical Outcomes.

    Babalola, K T / Arora, M / Ganugula, R / Agarwal, S K / Mohan, C / Kumar, M N V Ravi

    Pharmacological reviews

    2024  Volume 76, Issue 2, Page(s) 228–250

    Abstract: The role of advanced drug delivery strategies in drug repositioning and minimizing drug attrition rates, when applied early in drug discovery, is poised to increase the translational impact of various therapeutic strategies in disease prevention and ... ...

    Abstract The role of advanced drug delivery strategies in drug repositioning and minimizing drug attrition rates, when applied early in drug discovery, is poised to increase the translational impact of various therapeutic strategies in disease prevention and treatment. In this context, drug delivery to the lymphatic system is gaining prominence not only to improve the systemic bioavailability of various pharmaceutical drugs but also to target certain specific diseases associated with the lymphatic system. Although the role of the lymphatic system in lupus is known, very little is done to target drugs to yield improved clinical benefits. In this review, we discuss recent advances in drug delivery strategies to treat lupus, the various routes of drug administration leading to improved lymph node bioavailability, and the available technologies applied in other areas that can be adapted to lupus treatment. Moreover, this review also presents some recent findings that demonstrate the promise of lymphatic targeting in a preclinical setting, offering renewed hope for certain pharmaceutical drugs that are limited by efficacy in their conventional dosage forms. These findings underscore the potential and feasibility of such lymphatic drug-targeting approaches to enhance therapeutic efficacy in lupus and minimize off-target effects of the pharmaceutical drugs. SIGNIFICANCE STATEMENT: The World Health Organization estimates that there are currently 5 million humans living with some form of lupus. With limited success in lupus drug discovery, turning to effective delivery strategies with existing drug molecules, as well as those in the early stage of discovery, could lead to better clinical outcomes. After all, effective delivery strategies have been proven to improve treatment outcomes.
    MeSH term(s) Humans ; Drug Delivery Systems ; Pharmaceutical Preparations ; Lymphatic System ; Lupus Erythematosus, Systemic/drug therapy
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 209898-2
    ISSN 1521-0081 ; 0031-6997
    ISSN (online) 1521-0081
    ISSN 0031-6997
    DOI 10.1124/pharmrev.123.000938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Syntheses, crystal structures and Hirshfeld surface analyses of four mol-ecular salts of amitriptynol.

    Vinaya / Anil Kumar, Haleyur G / Mohan Kumar, Thaluru M / Lakshmana, Beliyaiah / Basavaraju, Yeriyur B / Yathirajan, Hemmige S / Parkin, Sean

    Acta crystallographica. Section E, Crystallographic communications

    2023  Volume 79, Issue Pt 5, Page(s) 451–457

    Abstract: The syntheses and crystal structures of four salts of amitriptynol ( ... ...

    Abstract The syntheses and crystal structures of four salts of amitriptynol (C
    Language English
    Publishing date 2023-04-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989023003225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Synthesis, crystal structure and Hirshfeld surface analysis of

    Geetha, Doreswamy / Anil Kumar, Haleyur G / Mohan Kumar, Thaluru M / Srinivasa, Gejjalagere R / Basavaraju, Yeriyur B / Yathirajan, Hemmige S / Parkin, Sean

    Acta crystallographica. Section E, Crystallographic communications

    2023  Volume 79, Issue Pt 5, Page(s) 512–515

    Abstract: The synthesis and crystal structure of the title compound, ... ...

    Abstract The synthesis and crystal structure of the title compound, C
    Language English
    Publishing date 2023-04-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041947-8
    ISSN 2056-9890 ; 1600-5368
    ISSN 2056-9890 ; 1600-5368
    DOI 10.1107/S2056989023003675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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