Result 1 - 10 of total 2484
Astronomy and Astrophysics
2017
| Publishing country | de |
|---|---|
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Microbiology resource announcements
2023 Volume 12, Issue 11, Page(s) e0060223
Abstract: Lactiplantibacillus ... ...
| Abstract | Lactiplantibacillus plantarum |
|---|---|
| Language | English |
| Publishing date | 2023-10-13 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2576-098X |
| ISSN (online) | 2576-098X |
| DOI | 10.1128/MRA.00602-23 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2024
| Language | English |
|---|---|
| Publishing date | 2024-02-09 |
| Publishing country | United States |
| Document type | Case Reports |
| ZDB-ID | 2012365-6 |
| ISSN | 1873-4626 ; 1934-3213 ; 1091-255X |
| ISSN (online) | 1873-4626 ; 1934-3213 |
| ISSN | 1091-255X |
| DOI | 10.1016/j.gassur.2024.02.009 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 5207: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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| Zs.MO 354: Show issues |
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Journal of the American Chemical Society
2024 Volume 146, Issue 8, Page(s) 5550–5559
Abstract: OspD is a ... ...
| Abstract | OspD is a radical |
|---|---|
| MeSH term(s) | S-Adenosylmethionine/chemistry ; Methionine ; Carbon ; Peptides/chemistry ; Amino Acids ; Racemethionine ; Valine |
| Chemical Substances | S-Adenosylmethionine (7LP2MPO46S) ; Methionine (AE28F7PNPL) ; Carbon (7440-44-0) ; Peptides ; Amino Acids ; Racemethionine (73JWT2K6T3) ; Valine (HG18B9YRS7) |
| Language | English |
| Publishing date | 2024-02-16 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 3155-0 |
| ISSN | 1520-5126 ; 0002-7863 |
| ISSN (online) | 1520-5126 |
| ISSN | 0002-7863 |
| DOI | 10.1021/jacs.3c13829 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Z 4' 55/32: Show issues | ||||
| Z 7.3: Show issues |
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British journal of sports medicine
2024 Volume 58, Issue 8, Page(s) 444–458
Abstract: Objectives: Systematically synthesise evidence of physical activity interventions for people experiencing homelessness (PEH).: Design: Mixed-methods systematic review.: Data sources: EMBASE, Web of Science, CINAHL, PubMed (MEDLINE), PsycINFO, ... ...
| Abstract | Objectives: Systematically synthesise evidence of physical activity interventions for people experiencing homelessness (PEH). Design: Mixed-methods systematic review. Data sources: EMBASE, Web of Science, CINAHL, PubMed (MEDLINE), PsycINFO, SPORTDiscus and Cochrane Library, searched from inception to October 2022. Eligibility criteria: PICO framework: population (quantitative/qualitative studies of PEH from high-income countries); intervention (physical activity); comparison (with/without comparator) and outcome (any health/well-being-related outcome). The risk of bias was assessed using Joanna Briggs Institute critical appraisal tools. Results: 3615 records were screened, generating 18 reports (17 studies, 11 qualitative and 6 quantitative (1 randomised controlled trial, 4 quasi-experimental, 1 analytical cross-sectional)) from the UK, USA, Denmark and Australia, including 554 participants (516 PEH, 38 staff). Interventions included soccer (n=7), group exercise (indoor (n=3), outdoor (n=5)) and individual activities (n=2). The risk of bias assessment found study quality to vary; with 6 being high, 6 moderate, 4 low and 1 very low. A mixed-methods synthesis identified physical and mental health benefits. Qualitative evidence highlighted benefits carried into wider life, the challenges of participating and the positive impact of physical activity on addiction. Qualitative and quantitative evidence was aligned demonstrating the mental health benefits of outdoor exercise and increased physical activity from indoor group exercise. Quantitative evidence also suggests improved musculoskeletal health, cardiovascular fitness, postural balance and blood lipid markers (p<0.05). Conclusion: Qualitative evidence suggests that physical activity interventions for PEH can benefit health and well-being with positive translation to wider life. There was limited positive quantitative evidence, although most was inconclusive. Although the evidence suggests a potential recommendation for physical activity interventions for PEH, results may not be transferable outside high-income countries. Further research is required to determine the effectiveness and optimal programme design. |
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| MeSH term(s) | Adult ; Humans ; Cross-Sectional Studies ; Exercise ; Sports ; Mental Health ; Ill-Housed Persons |
| Language | English |
| Publishing date | 2024-04-02 |
| Publishing country | England |
| Document type | Systematic Review ; Journal Article |
| ZDB-ID | 600592-5 |
| ISSN | 1473-0480 ; 0306-3674 |
| ISSN (online) | 1473-0480 |
| ISSN | 0306-3674 |
| DOI | 10.1136/bjsports-2023-107562 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.B 1893: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
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2022 Volume 53, Issue 3, Page(s) 999–1003
| MeSH term(s) | Humans ; Stroke/surgery ; Stroke/therapy ; Thrombectomy ; Treatment Outcome |
|---|---|
| Language | English |
| Publishing date | 2022-02-18 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 80381-9 |
| ISSN | 1524-4628 ; 0039-2499 ; 0749-7954 |
| ISSN (online) | 1524-4628 |
| ISSN | 0039-2499 ; 0749-7954 |
| DOI | 10.1161/STROKEAHA.122.036976 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 448: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
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Chemphyschem : a European journal of chemical physics and physical chemistry
2024 , Page(s) e202400073
Abstract: Surface segregation, whereby the surface composition of an alloy differs systematically from the bulk, has historically been hard to study, because it requires experimental and modeling methods that span alloy composition space. In this work, we study ... ...
| Abstract | Surface segregation, whereby the surface composition of an alloy differs systematically from the bulk, has historically been hard to study, because it requires experimental and modeling methods that span alloy composition space. In this work, we study surface segregation in catalytically relevant noble and platinum-group metal alloys with a focus on three ternary systems: AgAuCu, AuCuPd, and CuPdPt. We develop a data set of 2478 slabs with those compositions including all three low-index crystallographic orientations relaxed with Density Functional Theory using the PBEsol functional with D3 dispersion corrections. We fine-tune a machine learning model on this data and use the model in a series of 1800 Monte Carlo simulations spanning ternary composition space for each surface orientation and ternary chemical system. The results of these simulations are validated against prior experimental surface segregation data collected using composition spread alloy films for AgAuCu and AuCuPd. Our findings reveal that simulations conducted using the (110) orientation most closely match experimentally observed surface segregation trends, and while predicted trends qualitatively match observation, biases in the PBEsol functional limit numeric accuracy. This study advances understanding of surface segregation and the utility of computational studies and highlights the need for further improvements in simulation accuracy. |
|---|---|
| Language | English |
| Publishing date | 2024-03-22 |
| Publishing country | Germany |
| Document type | Journal Article |
| ZDB-ID | 2025223-7 |
| ISSN | 1439-7641 ; 1439-4235 |
| ISSN (online) | 1439-7641 |
| ISSN | 1439-4235 |
| DOI | 10.1002/cphc.202400073 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Journal of the American Heart Association
2024 Volume 13, Issue 8, Page(s) e034115
Abstract: Background: We performed a review of acute stroke trials to determine features associated with premature termination of trial enrollment, defined by the authors as not meeting preplanned sample size.: Methods and results: MEDLINE was searched for ... ...
| Abstract | Background: We performed a review of acute stroke trials to determine features associated with premature termination of trial enrollment, defined by the authors as not meeting preplanned sample size. Methods and results: MEDLINE was searched for randomized clinical stroke trials published in 9 major clinical journals between 2013 and 2022. We included randomized clinical trials that were phase 2 or 3 with a preplanned sample size ≥100 and a time-to-treatment within 24 hours of onset for transient ischemic attack, ischemic stroke, or intracerebral hemorrhage. Data were abstracted on trial features including trial design, inclusion criteria, imaging, location and number of sites, masking, treatment complexity, control group (standard therapy, placebo), industry involvement, and preplanned stopping rules (futility and efficacy). Least absolute shrinkage and selection operator regression was used to select the most important factors associated with premature termination; then, a multivariable logistic regression was fit including only the least absolute shrinkage and selection operator selected variables. Of 1475 studies assessed, 98 trials met eligibility criteria. Forty-five (46%) trials were prematurely terminated, of which 27% were stopped for benefit/efficacy, 20% for lack of money/slow enrollment, 18% for futility, 16% for newly available evidence, 17% for other reasons, and 4% due to harm. Complex trials (adjusted odds ratio [aOR], 2.76 [95% CI, 1.13-7.49]), presence of a futility rule (aOR, 4.43 [95% CI, 1.62-17.91]), and exclusion of prestroke dependency (none/slight disability only; aOR, 2.19 [95% CI, 0.84-6.72] versus dependency allowed) were identified as the strongest predictors. Conclusions: Nearly half of acute stroke trials were terminated prematurely. Broadening inclusion criteria and simplifying trial design may decrease the likelihood of unplanned termination, whereas planned futility analyses may appropriately terminate trials early, saving money and resources. |
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| MeSH term(s) | Humans ; Stroke/therapy ; Stroke/drug therapy ; Ischemic Attack, Transient ; Cerebral Hemorrhage ; Ischemic Stroke ; Sample Size |
| Language | English |
| Publishing date | 2024-04-12 |
| Publishing country | England |
| Document type | Review ; Journal Article |
| ZDB-ID | 2653953-6 |
| ISSN | 2047-9980 ; 2047-9980 |
| ISSN (online) | 2047-9980 |
| ISSN | 2047-9980 |
| DOI | 10.1161/JAHA.124.034115 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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2022 Volume 14, Issue 2, Page(s) e22275
Abstract: Inguinal hernia repair is a commonly performed surgical procedure and generally is well tolerated with minimal complications. We present the case of a 70-year-old male with an anomalous tract involving the subcutaneous tissue and cecum after an open ... ...
| Abstract | Inguinal hernia repair is a commonly performed surgical procedure and generally is well tolerated with minimal complications. We present the case of a 70-year-old male with an anomalous tract involving the subcutaneous tissue and cecum after an open right inguinal hernia repair via plug and patch approach. A partial cecectomy with appendectomy with excision of the tract was performed. While most complications are relatively minor and fistulas are quite rare, mesh migration is a possibility that should be considered during preoperative planning for recurrent hernia surgery. |
|---|---|
| Language | English |
| Publishing date | 2022-02-16 |
| Publishing country | United States |
| Document type | Case Reports |
| ZDB-ID | 2747273-5 |
| ISSN | 2168-8184 |
| ISSN | 2168-8184 |
| DOI | 10.7759/cureus.22275 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
2024 Volume 32, Issue 4, Page(s) 1000–1007
Abstract: Purpose: Current evidence around the management of osteotomy-related infection is insufficient to robustly underpin the expert statements formulated by a recent European consensus statement. We present a review of a large case series in a high-volume ... ...
| Abstract | Purpose: Current evidence around the management of osteotomy-related infection is insufficient to robustly underpin the expert statements formulated by a recent European consensus statement. We present a review of a large case series in a high-volume osteotomy practice to contribute to the understanding of the incidence, management and outcome of infection in this subspecialty area. Methods: Analyses of two prospectively collected databases for all osteotomy around the knee and infections related to osteotomy were performed, along with a review of hospital readmission data to capture all osteotomy-related infections. Clinical notes were reviewed to assess patient demographics, incidence of infection, how infection was managed and clinical outcome. Results: In a series of 822 osteotomies in 755 patients, there were 21 (2.8%) cases of suspected infection. Twelve (1.6%) were contemporaneously deemed 'superficial' and nine confirmed 'deep' infections (1.2%). Deep infections were all successfully managed with wound debridement, with or without plate removal, depending on union and time from initial surgery. One of these infections was noted during a revision procedure, but no revision was carried out as a direct result of infection, no external fixation was required and no infected nonunions were experienced. Conclusion: All of the cases in this series were managed successfully with debridement ± removal of the plate, without the need for revision or external fixation. Any potential signs of infection around an osteotomy, especially in the case of medial high tibial osteotomy, should raise awareness for deep infection and the need for further surgery due to the limited overlying soft tissue cover. This evidence supports the recent European Society of Sports Traumatology, Knee Surgery and Arthroscopy algorithm. Level of evidence: Level IV, case series. |
|---|---|
| MeSH term(s) | Humans ; Incidence ; Tibia/surgery ; Knee Joint/surgery ; Knee ; Osteoarthritis, Knee/surgery ; Osteotomy/adverse effects ; Osteotomy/methods ; Retrospective Studies ; Treatment Outcome |
| Language | English |
| Publishing date | 2024-03-12 |
| Publishing country | Germany |
| Document type | Review ; Journal Article |
| ZDB-ID | 1159064-6 |
| ISSN | 1433-7347 ; 0942-2056 |
| ISSN (online) | 1433-7347 |
| ISSN | 0942-2056 |
| DOI | 10.1002/ksa.12119 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 3742: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
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