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  1. Article ; Online: The terminology of progestogens – a clarification.

    Raknes, Guttorm

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2021  Volume 141, Issue 11

    Title translation Progestageners terminologi - en presisering.
    Language Norwegian
    Publishing date 2021-08-16
    Publishing country Norway
    Document type Journal Article ; Comment
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.21.0527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correction: The terminology of progestogens.

    Raknes, Guttorm

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2021  Volume 141, Issue 11

    Title translation Rettelse: Progestageners terminologi.
    Language Norwegian
    Publishing date 2021-06-21
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.21.0498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: G. Raknes responds.

    Raknes, Guttorm

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2021  Volume 141, Issue 11

    Title translation G. Raknes svarer.
    Language Norwegian
    Publishing date 2021-08-16
    Publishing country Norway
    Document type Journal Article ; Comment
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.21.0529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Off-label?

    Raknes, Guttorm

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2018  Volume 138, Issue 17

    Title translation Utenfor etiketten?
    MeSH term(s) Humans ; Off-Label Use
    Language Norwegian
    Publishing date 2018-10-19
    Publishing country Norway
    Document type Editorial
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.18.0522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Legevakt og reiseavstand.

    Raknes, Guttorm

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2016  Volume 136, Issue 3, Page(s) 252

    Language Norwegian
    Publishing date 2016-02-09
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.15.1321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Excess non-COVID-19 mortality in Norway 2020-2022.

    Raknes, Guttorm / Fagerås, Stephanie Jebsen / Sveen, Kari Anne / Júlíusson, Pétur Benedikt / Strøm, Marianne Sørlie

    BMC public health

    2024  Volume 24, Issue 1, Page(s) 244

    Abstract: Background: Causes of death other than COVID-19 seem to contribute significantly to the excess mortality observed during the 2020-2022 pandemic. In this study, we explore changes in non-COVID-19 causes of death in Norway during the COVID-19 pandemic ... ...

    Abstract Background: Causes of death other than COVID-19 seem to contribute significantly to the excess mortality observed during the 2020-2022 pandemic. In this study, we explore changes in non-COVID-19 causes of death in Norway during the COVID-19 pandemic from March 2020 to December 2022.
    Methods: We performed a population-based cross-sectional study on data from the Norwegian Cause of Death Registry. All recorded deaths from 1st January 2010 to 31st December 2022 were included. The main outcome measures were the number of deaths and age-standardised death rate (ASMR) per 100000 population from the major cause of death groups in 2020, 2021 and 2022. The predicted number of deaths and ASMRs were forecasted with a 95% prediction interval constructed from a general linear regression model based on the corresponding number of deaths and rates from the preceding ten prepandemic years (2010-2019). We also examined whether there were deviations from expected seasonality in the pandemic period based on prepandemic monthly data from 2010-2019. The cumulative number of deaths and ASMR were estimated based on monthly mortality data.
    Results: There was significant excess mortality (number of deaths) in 2021 and 2022 for all causes (3.7% and 14.5%), for cardiovascular diseases (14.3% and 22.0%), and for malignant tumours in 2022 (3.5%). In terms of ASMR, there was excess mortality in 2021 and 2022 for all causes (2.9% and 13.7%), and for cardiovascular diseases (16.0% and 25,8%). ASMR was higher than predicted in 2022 for malignant tumours (2.3%). There were fewer deaths than predicted from respiratory diseases (except COVID-19) in 2020 and 2021, and from dementia in 2021 and 2022. From March 2020 to December 2022, there were cumulatively 3754 (ASMR 83.8) more non-COVID-19 deaths than predicted, of which 3453 (ASMR: 79.6) were excess deaths from cardiovascular disease, 509 (ASMR 4.0) from malignant tumours. Mortality was lower than predicted for respiratory diseases (-1889 (ASMR: -44.3)), and dementia (-530 (ASMR -18.5)).
    Conclusions: There was considerable excess non-COVID-19 mortality in Norway from March 2020 until December 2022, mainly due to excess cardiovascular deaths. For respiratory diseases and dementia, mortality was lower than predicted.
    MeSH term(s) Humans ; Female ; Cardiovascular Diseases ; Cross-Sectional Studies ; Pandemics ; Perinatal Death ; COVID-19 ; Norway/epidemiology ; Neoplasms ; Dementia
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-17515-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Problematic proton pump inhibitors.

    Raknes, Guttorm / Giverhaug, Trude

    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

    2020  Volume 140, Issue 16

    Title translation Problematiske protonpumpehemmere.
    MeSH term(s) Humans ; Proton Pump Inhibitors/adverse effects
    Chemical Substances Proton Pump Inhibitors
    Language Norwegian
    Publishing date 2020-11-09
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 603504-8
    ISSN 0807-7096 ; 0029-2001
    ISSN (online) 0807-7096
    ISSN 0029-2001
    DOI 10.4045/tidsskr.20.0414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  8. Article ; Online: No change in the consumption of thyroid hormones after starting low dose naltrexone (LDN): a quasi-experimental before-after study.

    Raknes, Guttorm / Småbrekke, Lars

    BMC endocrine disorders

    2020  Volume 20, Issue 1, Page(s) 151

    Abstract: Background: Low dose naltrexone (LDN) is reported to have beneficial effects in several autoimmune diseases. The purpose of this study was to examine whether starting LDN was followed by changes in the dispensing of thyroid hormones to patients with ... ...

    Abstract Background: Low dose naltrexone (LDN) is reported to have beneficial effects in several autoimmune diseases. The purpose of this study was to examine whether starting LDN was followed by changes in the dispensing of thyroid hormones to patients with hypothyroidism.
    Methods: We performed a quasi-experimental before-after study based on the Norwegian Prescription Database. Study participants were identified by using reimbursement codes for hypothyroidism. Cumulative dispensed Defined Daily Doses and the number of users of triiodothyronine (T3) and levothyroxine (LT4) 1 year before and after the first LDN prescription was compared in three groups based on LDN exposure.
    Results: We identified 898 patients that met the inclusion criteria. There was no association between starting LDN and the subsequent dispensing of thyroid hormones. If anything, there was a tendency towards increasing LT4 consumption with increasing LDN exposure.
    Conclusion: The results of this study do not support claims of efficacy of LDN in hypothyroidism.
    Language English
    Publishing date 2020-10-01
    Publishing country England
    Document type Journal Article
    ISSN 1472-6823
    ISSN (online) 1472-6823
    DOI 10.1186/s12902-020-00630-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Correction: Low dose naltrexone: Effects on medication in rheumatoid and seropositive arthritis. A nationwide register-based controlled quasi-experimental before-after study.

    Raknes, Guttorm / Småbrekke, Lars

    PloS one

    2019  Volume 14, Issue 10, Page(s) e0223545

    Abstract: This corrects the article DOI: 10.1371/journal.pone.0212460.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pone.0212460.].
    Language English
    Publishing date 2019-10-01
    Publishing country United States
    Document type Published Erratum
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0223545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Changes in the consumption of antiepileptics and psychotropic medicines after starting low dose naltrexone: A nation-wide register-based controlled before-after study.

    Raknes, Guttorm / Småbrekke, Lars

    Scientific reports

    2019  Volume 9, Issue 1, Page(s) 15085

    Abstract: In this controlled before-after study based on data from the Norwegian Prescription Database, we examine whether starting off-label use of Low Dose Naltrexone (LDN) is followed by changes in the consumption of psychotropic medicines including ... ...

    Abstract In this controlled before-after study based on data from the Norwegian Prescription Database, we examine whether starting off-label use of Low Dose Naltrexone (LDN) is followed by changes in the consumption of psychotropic medicines including antiepileptics. Patients that collected LDN for the first time in 2013 (N = 11247) were included and stratified into three groups based on LDN exposure. We compared differences in means of cumulative number of defined daily doses (DDD) as well as changes in the number of users one year before and one year after starting LDN. There was a dose-response association between increasing LDN exposure and reductions in the number of users of antiepileptics, antipsychotics and antidepressants. There were significant difference-in-differences in DDDs between the groups with the lowest and highest LDN exposure of antipsychotics (1.4 DDD, 95% CI 0.4 to 2.3, p = 0.007), and in number of users of antiepileptics (3.1% points, 95% CI 1.6% to 4.6%, p < 0.001), antipsychotics (2.1% points, 95% CI 1.2% to 3%, p < 0.001), and antidepressants (2.8% points, 95% CI 1.1% to 4.4%, p = 0.001). The findings show an association between the initiation of persistent LDN use and reduced consumption of several psychotropic medicines and antiepileptics. Beneficial effects of LDN in the treatment of psychiatric diseases cannot be ruled out.
    MeSH term(s) Anticonvulsants/pharmacology ; Antidepressive Agents/pharmacology ; Antipsychotic Agents/pharmacology ; Dose-Response Relationship, Drug ; Humans ; Naltrexone/pharmacology ; Norway ; Psychotropic Drugs/pharmacology ; Registries ; Treatment Outcome
    Chemical Substances Anticonvulsants ; Antidepressive Agents ; Antipsychotic Agents ; Psychotropic Drugs ; Naltrexone (5S6W795CQM)
    Language English
    Publishing date 2019-10-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-019-51569-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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