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  1. Article ; Online: Intrinsically High Resistance of Candida glabrata to Hydrogen Peroxide and Its Reversal in a Fluconazole-Resistant Mutant.

    Edlind, Tom / Katiyar, Santosh

    Antimicrobial agents and chemotherapy

    2022  Volume 66, Issue 9, Page(s) e0072122

    MeSH term(s) Azoles ; Candida glabrata/genetics ; Drug Resistance, Fungal/genetics ; Fluconazole/pharmacology ; Hydrogen Peroxide/pharmacology
    Chemical Substances Azoles ; Fluconazole (8VZV102JFY) ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2022-08-02
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00721-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 809: Show issues Location:
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    Einzelsignatur: Show issues

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  2. Article ; Online: New Locus for Candida glabrata Sequence-Based Strain Typing Provides Evidence for Nosocomial Transmission.

    Katiyar, Santosh / Edlind, Tom

    Journal of clinical microbiology

    2021  Volume 59, Issue 4

    MeSH term(s) Candida glabrata/genetics ; Candidiasis ; Cross Infection ; Humans ; Mycological Typing Techniques
    Language English
    Publishing date 2021-03-19
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.02933-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1188: Show issues Location:
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  3. Article ; Online: Locus CauMT1 Provides a Higher-Resolution Alternative to Ribosomal Gene Sequencing for Initial Candida auris Genotyping.

    Katiyar, Santosh / Edlind, Tom

    Journal of clinical microbiology

    2020  Volume 58, Issue 9

    MeSH term(s) Antifungal Agents/therapeutic use ; Candida/genetics ; Candidiasis/diagnosis ; Candidiasis/drug therapy ; Genotype ; Humans
    Chemical Substances Antifungal Agents
    Keywords covid19
    Language English
    Publishing date 2020-08-24
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.01039-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1188: Show issues Location:
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  4. Article ; Online: Investigating Bacopa monnieri L. Therapeutic Potential for the Treatment of Neurological Diseases.

    Srivastava, Pratima / Yadav, Dhananjay / Singh, Santosh Kumar / Kim, Sung Hae / Singh, Shivendra / Katiyar, Shweta / Song, Minseok

    Current pharmaceutical design

    2024  

    Abstract: The popular perennial creeping plant known as Bacopa monnieri (also known as Brahmi) is being utilized in the Indian Ayurvedic medicine practice. It has a variety of bioactive phytoconstituents that have been used therapeutically to treat a number of ... ...

    Abstract The popular perennial creeping plant known as Bacopa monnieri (also known as Brahmi) is being utilized in the Indian Ayurvedic medicine practice. It has a variety of bioactive phytoconstituents that have been used therapeutically to treat a number of serious illnesses. Ancient Vedic scholars used this herb because of its pharmacological effects, particularly as a nerve booster and nootropic supporter. However, it is vital to comprehend the active phytochemical components of Bacopa monnieri extract (BME) and their molecular mechanisms in order to better grasp the effect of BME on neurological illnesses and diseases. Understanding its active phytochemical constituents and their molecular processes is essential. Numerous clinical investigations indicated that BME may have neuroprotective benefits, so it is worthwhile to re-evaluate this wellknown plant. Here, we focused on neurological problems as we examined the pharmacological and phytochemical characteristics of BME. For their effective usage in neuroprotection and cognition, many clinical concerns and the synergistic potential of Bacopa extract have been investigated. Alzheimer's disease is a neurological condition caused by the production of reactive oxygen species, which also causes amyloid-beta (A) and tau protein aggregation and increases neuro-inflammation and neurotoxicity. Our review offers a more indepth molecular understanding of the neuroprotective functions of BME, which can also be connected to its therapeutic management of neurological illnesses and cognitive-improving effects.
    Language English
    Publishing date 2024-03-18
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/0113816128288698240305094945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4714: Show issues Location:
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  5. Article ; Online: Dietary proanthocyanidins inhibit UV radiation-induced skin tumor development through functional activation of the immune system.

    Katiyar, Santosh K

    Molecular nutrition & food research

    2016  Volume 60, Issue 6, Page(s) 1374–1382

    Abstract: The incidence of skin cancer is equivalent to the incidence of malignancies in all other organs combined. The main risk factor for this disease is overexposure of the skin to solar ultraviolet (UV) radiation. UV irradiation induces inflammation, ... ...

    Abstract The incidence of skin cancer is equivalent to the incidence of malignancies in all other organs combined. The main risk factor for this disease is overexposure of the skin to solar ultraviolet (UV) radiation. UV irradiation induces inflammation, oxidative stress, DNA damage, and suppression of the immune system in the skin, which together contribute to carcinogenesis. The use of dietary phytochemicals shows great promise as a complementary and alternative strategy for skin cancer prevention. Grape seed proanthocyanidins (GSPs) have been tested extensively for their anti-skin cancer effect using in vivo animal models. Supplementation of an AIN76A control diet with GSPs (0.2 and 0.5%, w/w) significantly inhibits UV radiation-induced skin tumor development as well as malignant transformation of papillomas to carcinoma in mice. The inhibition of UVB-induced skin tumor development by GSPs is mediated through interrelated mechanisms of action including: (i) inhibition of inflammation, (ii) rapid repair of damaged DNA, and (iii) stimulation of immune system. Additionally, the chemopreventive effects of GSPs involve DNA repair-dependent functional activation of antigen-presenting cells and stimulation of CD8(+) effector T cells. These effects of GSPs could be useful in attenuation of the adverse effects of UV radiation and may have health benefits in humans.
    Language English
    Publishing date 2016-06
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.201501026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Emerging Phytochemicals for the Prevention and Treatment of Head and Neck Cancer.

    Katiyar, Santosh K

    Molecules (Basel, Switzerland)

    2016  Volume 21, Issue 12

    Abstract: Despite the development of more advanced medical therapies, cancer management remains a problem. Head and neck squamous cell carcinoma (HNSCC) is a particularly challenging malignancy and requires more effective treatment strategies and a reduction in ... ...

    Abstract Despite the development of more advanced medical therapies, cancer management remains a problem. Head and neck squamous cell carcinoma (HNSCC) is a particularly challenging malignancy and requires more effective treatment strategies and a reduction in the debilitating morbidities associated with the therapies. Phytochemicals have long been used in ancient systems of medicine, and non-toxic phytochemicals are being considered as new options for the effective management of cancer. Here, we discuss the growth inhibitory and anti-cell migratory actions of proanthocyanidins from grape seeds (GSPs), polyphenols in green tea and honokiol, derived from the
    MeSH term(s) Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis/drug effects ; Biphenyl Compounds/pharmacology ; Carcinoma, Squamous Cell/drug therapy ; Catechin/analogs & derivatives ; Catechin/pharmacology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Survival/drug effects ; Drug Evaluation, Preclinical ; Head and Neck Neoplasms/drug therapy ; Humans ; Lignans/pharmacology ; Magnolia/chemistry ; Polyphenols/pharmacology ; Proanthocyanidins/pharmacology ; Squamous Cell Carcinoma of Head and Neck ; Tea/chemistry ; Vitis/chemistry
    Chemical Substances Antineoplastic Agents, Phytogenic ; Biphenyl Compounds ; Lignans ; Polyphenols ; Proanthocyanidins ; Tea ; honokiol (11513CCO0N) ; Catechin (8R1V1STN48) ; epigallocatechin gallate (BQM438CTEL)
    Language English
    Publishing date 2016-11-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules21121610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  7. Article ; Online: Hsp90 inhibitor can inhibit UV carcinogenesis.

    Katiyar, Santosh K

    The Journal of investigative dermatology

    2015  Volume 135, Issue 4, Page(s) 945–947

    Abstract: Extensive exposure to solar UVR is a well-recognized etiologic factor for cutaneous non-melanoma skin cancer. In this issue of the Journal, Singh et al. show that topical treatment of the skin with 17-[allylamino]-17-demethoxygeldanamycin (17AAG), a heat- ...

    Abstract Extensive exposure to solar UVR is a well-recognized etiologic factor for cutaneous non-melanoma skin cancer. In this issue of the Journal, Singh et al. show that topical treatment of the skin with 17-[allylamino]-17-demethoxygeldanamycin (17AAG), a heat-shock protein 90 (Hsp90) inhibitor, prevents UVR-induced squamous cell carcinomas (SCCs) in mice. The inhibitory effect of 17AAG on SCC was associated with the inhibition of the UVR-induced (i) hyperplastic response, (ii) Hsp90β-PKCɛ interaction, and (iii) pStat3 and pAkt expression in mouse skin.
    MeSH term(s) Animals ; Benzoquinones/chemistry ; HSP90 Heat-Shock Proteins/metabolism ; Humans ; Lactams, Macrocyclic/chemistry ; Melanoma/metabolism ; Neoplasms, Radiation-Induced/metabolism ; Skin Neoplasms/metabolism ; Melanoma, Cutaneous Malignant
    Chemical Substances Benzoquinones ; HSP90 Heat-Shock Proteins ; Lactams, Macrocyclic ; tanespimycin (4GY0AVT3L4)
    Language English
    Publishing date 2015-03-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Comment
    ZDB-ID 80136-7
    ISSN 1523-1747 ; 0022-202X
    ISSN (online) 1523-1747
    ISSN 0022-202X
    DOI 10.1038/jid.2014.504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui VI Zs.124: Show issues Location:
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  9. Article: Artificial Bee Colony Algorithm for Fresh Food Distribution without Quality Loss by Delivery Route Optimization

    Katiyar, Sapna / Khan, Rijwan / Kumar, Santosh

    Journal of food quality. 2021 Oct. 15, v. 2021

    2021  

    Abstract: This paper enlightens the use of artificial intelligence (AI) for distribution of fresh foods by searching more viable route to keep intact the food attributes. In recent years, very hard-hitting competition is for food industries because of the ... ...

    Abstract This paper enlightens the use of artificial intelligence (AI) for distribution of fresh foods by searching more viable route to keep intact the food attributes. In recent years, very hard-hitting competition is for food industries because of the individuals living standards and their responsiveness for fresh food products demand within stipulated time period. Food industry deals with the extensive kind of activities such as food processing, food packaging and distribution, and instrumentation and control. To meet market demand, customer satisfaction, and maintaining its own brand and ranking on global scale, artificial intelligence can play a vibrant role in decision-making by providing analytical solutions with adjusting available resources. Therefore, by integrating innovative technologies for fresh food distribution, potential benefits have been increased, and simultaneously risk associated with the food quality is reduced. Time is a major factor upon which food quality depends; hence, time required to complete the task must be minimized, and it is achieved by reducing the distance travelled; so, path optimization is the key for the overall task. Swarm intelligence (SI) is a subfield of artificial intelligence and consists of many algorithms. SI is a branch of nature-inspired algorithm, having a capability of global search, and gives optimized solution for real-time problems adaptive in nature. An artificial bee colony (ABC) optimization and cuckoo search (CS) algorithm also come into the category of SI algorithm. Researchers have implemented ABC algorithm and CS algorithm to optimize the distribution route for fresh food delivery in time window along with considering other factors: fixed number of delivery vehicles and fixed cost and fuel by covering all service locations. Results show that this research provides an efficient approach, i.e., artificial bee colony algorithm for fresh food distribution in time window without penalty and food quality loss.
    Keywords algorithms ; artificial intelligence ; consumer satisfaction ; decision making ; food industry ; food quality ; instrumentation ; risk ; supply balance ; swarms
    Language English
    Dates of publication 2021-1015
    Publishing place Hindawi
    Document type Article
    ZDB-ID 2175284-9
    ISSN 1745-4557
    ISSN 1745-4557
    DOI 10.1155/2021/4881289
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Proanthocyanidins from grape seeds inhibit UV-radiation-induced immune suppression in mice: detection and analysis of molecular and cellular targets.

    Katiyar, Santosh K

    Photochemistry and photobiology

    2014  Volume 91, Issue 1, Page(s) 156–162

    Abstract: Ultraviolet (UV)-radiation-induced immunosuppression has been linked with the risk of skin carcinogenesis. Approximately, 2 million new cases of skin cancers, including melanoma and nonmelanoma, diagnosed each year in the USA and therefore have a ... ...

    Abstract Ultraviolet (UV)-radiation-induced immunosuppression has been linked with the risk of skin carcinogenesis. Approximately, 2 million new cases of skin cancers, including melanoma and nonmelanoma, diagnosed each year in the USA and therefore have a tremendous bad impact on public health. Dietary phytochemicals are promising options for the development of effective strategy for the prevention of photodamaging effects of UV radiation including the risk of skin cancer. Grape seed proanthocyanidins (GSPs) are such phytochemicals. Dietary administration of GSPs with AIN76A control diet significantly inhibits UV-induced skin tumor development as well as suppression of immune system. UV-induced suppression of immune system is commonly determined using contact hypersensitivity (CHS) model which is a prototype of T-cell-mediated immune response. We present evidence that inhibition of UV-induced suppression of immune system by GSPs is mediated through: (i) the alterations in immunoregulatory cytokines, interleukin (IL)-10 and IL-12, (ii) DNA repair, (iii) stimulation of effector T cells and (iv) DNA repair-dependent functional activation of dendritic cells in mouse model. These information have important implications for the use of GSPs as a dietary supplement in chemoprevention of UV-induced immunosuppression as well as photocarcinogenesis.
    MeSH term(s) Animals ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cytokines/metabolism ; DNA Damage ; DNA Repair ; Grape Seed Extract/isolation & purification ; Grape Seed Extract/pharmacology ; Immune System/drug effects ; Immune System/radiation effects ; Mice ; Proanthocyanidins/isolation & purification ; Proanthocyanidins/pharmacology ; Ultraviolet Rays
    Chemical Substances Cytokines ; Grape Seed Extract ; Grape Seed Proanthocyanidins ; Proanthocyanidins
    Language English
    Publishing date 2014-09-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ZDB-ID 123540-0
    ISSN 1751-1097 ; 0031-8655
    ISSN (online) 1751-1097
    ISSN 0031-8655
    DOI 10.1111/php.12330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1686: Show issues Location:
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