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  1. Article: Logistics Flow Optimization for Advanced Management of the Crisis Situation.

    Chakir, Imane / El Khaili, Mohamed / Mestari, Mohamed

    Procedia computer science

    2020  Volume 175, Page(s) 419–426

    Abstract: Our work has been carried out with the aim of providing a solution to decision-making problems encountered in information systems for supply chains in crisis situation. The supply chain represents a competitive advantage that companies seek to perpetuate. ...

    Abstract Our work has been carried out with the aim of providing a solution to decision-making problems encountered in information systems for supply chains in crisis situation. The supply chain represents a competitive advantage that companies seek to perpetuate. It aims to optimize the exchanges, or flows, that the company maintains with its suppliers and its customers. These flows can be of various natures. It can be information flows relating to supplies or product design, financial flows linked to purchases, or even flows of goods. The crisis management logistics is getting more and more attention, especially in the current context of the COVID-19 pandemic. For these systems, where it is never very easy to anticipate the evolution of the environment, the forms of changes undergone are varied and rapid. We aim to provide an answer to these challenges, in an approach that links optimization methods to the paradigm of artificial intelligence. We therefore propose to find mathematical models, and inter-agent cooperation protocols, to minimize the risk of stock shortage in any area of ​​the supply chain.
    Keywords covid19
    Language English
    Publishing date 2020-08-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2557358-5
    ISSN 1877-0509
    ISSN 1877-0509
    DOI 10.1016/j.procs.2020.07.059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Logistics Flow Optimization for Advanced Management of the Crisis Situation

    Chakir, Imane / El Khaili, Mohamed / Mestari, Mohamed

    Procedia computer science

    Abstract: Our work has been carried out with the aim of providing a solution to decision-making problems encountered in information systems for supply chains in crisis situation The supply chain represents a competitive advantage that companies seek to perpetuate ... ...

    Abstract Our work has been carried out with the aim of providing a solution to decision-making problems encountered in information systems for supply chains in crisis situation The supply chain represents a competitive advantage that companies seek to perpetuate It aims to optimize the exchanges, or flows, that the company maintains with its suppliers and its customers These flows can be of various natures It can be information flows relating to supplies or product design, financial flows linked to purchases, or even flows of goods The crisis management logistics is getting more and more attention, especially in the current context of the COVID-19 pandemic For these systems, where it is never very easy to anticipate the evolution of the environment, the forms of changes undergone are varied and rapid We aim to provide an answer to these challenges, in an approach that links optimization methods to the paradigm of artificial intelligence We therefore propose to find mathematical models, and inter-agent cooperation protocols, to minimize the risk of stock shortage in any area of ​​the supply chain
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #728819
    Database COVID19

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  3. Article ; Online: GAMOS/GEANT4 simulation and comparison study of X-ray narrow-spectrum series at the national Secondary Standard Dosimetry Laboratory of Morocco.

    Al-Tuweity, Jawaher / Sadiq, Younes / Mouktafi, Amine / Arce, Pedro / Fathi, Imane / Mohammed, Maged / Azougagh, Mohamed / Alibrahmi, El Mehdi / Boukhal, Hamid / Chakir, El Mahjoub

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

    2021  Volume 175, Page(s) 109789

    Abstract: This study aimed to simulate the X-ray Irradiator narrow-spectrum series and compare the results with experimental and recommended values in ISO standards. X-Ray beam qualities of N-40 to N-300 were established experimentally at the national Secondary ... ...

    Abstract This study aimed to simulate the X-ray Irradiator narrow-spectrum series and compare the results with experimental and recommended values in ISO standards. X-Ray beam qualities of N-40 to N-300 were established experimentally at the national Secondary Standard Dosimetry Laboratory (SSDL) of Morocco in purpose of calibrating radiation protection- level. The variations between the first half-value layer (1
    Language English
    Publishing date 2021-05-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1142596-9
    ISSN 1872-9800 ; 0883-2889 ; 0969-8043
    ISSN (online) 1872-9800
    ISSN 0883-2889 ; 0969-8043
    DOI 10.1016/j.apradiso.2021.109789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.279: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Anti-Cancer Effect of Moroccan Cobra

    Lafnoune, Ayoub / Lee, Su-Yeon / Heo, Jin-Yeong / Gourja, Imane / Darkaoui, Bouchra / Abdelkafi-Koubaa, Zaineb / Chgoury, Fatima / Daoudi, Khadija / Chakir, Salma / Cadi, Rachida / Mounaji, Khadija / Srairi-Abid, Najet / Marrakchi, Naziha / Shum, David / Seo, Haeng-Ran / Oukkache, Naoual

    Toxins

    2021  Volume 13, Issue 6

    Abstract: Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of cancer related death. An alternative to the surgical treatments and drugs, such as sorafenib, ... ...

    Abstract Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of cancer related death. An alternative to the surgical treatments and drugs, such as sorafenib, commonly used in medicine is necessary to overcome this public health problem. In this study, we determine the anticancer effect on HCC of Moroccan cobra
    MeSH term(s) Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Hepatocellular/drug therapy ; Cell Culture Techniques ; Cells, Cultured ; Dose-Response Relationship, Drug ; Elapid Venoms/pharmacology ; Hepatocytes/drug effects ; Humans ; Liver Neoplasms/drug therapy ; Naja haje
    Chemical Substances Antineoplastic Agents ; Elapid Venoms
    Language English
    Publishing date 2021-06-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins13060402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Anti-Cancer Effect of Moroccan Cobra Naja haje Venom and Its Fractions against Hepatocellular Carcinoma in 3D Cell Culture

    Ayoub Lafnoune / Su-Yeon Lee / Jin-Yeong Heo / Imane Gourja / Bouchra Darkaoui / Zaineb Abdelkafi-Koubaa / Fatima Chgoury / Khadija Daoudi / Salma Chakir / Rachida Cadi / Khadija Mounaji / Najet Srairi-Abid / Naziha Marrakchi / David Shum / Haeng-Ran Seo / Naoual Oukkache

    Toxins, Vol 13, Iss 402, p

    2021  Volume 402

    Abstract: Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of cancer related death. An alternative to the surgical treatments and drugs, such as sorafenib, ... ...

    Abstract Hepatocellular carcinoma (HCC) is the most common primary liver cancer in adults, the fifth most common malignancy worldwide and the third leading cause of cancer related death. An alternative to the surgical treatments and drugs, such as sorafenib, commonly used in medicine is necessary to overcome this public health problem. In this study, we determine the anticancer effect on HCC of Moroccan cobra Naja haje venom and its fraction obtained by gel filtration chromatography against Huh7.5 cancer cell line. Cells were grown together with WI38 human fibroblast cells, LX2 human hepatic stellate cell line, and human endothelial cells (HUVEC) in MCTS (multi-cellular tumor spheroids) models. The hepatotoxicity of venom and its fractions were also evaluated using the normal hepatocytes cell line (Fa2N-4 cells). Our results showed that an anti HCC activity of Moroccan cobra Naja haje venom and, more specifically, the F7 fraction of gel filtration chromatography exhibited the greatest anti-hepatocellular carcinoma effect by decreasing the size of MCTS. This effect is associated with a low toxicity against normal hepatocytes. These results strongly suggest that the F7 fraction of Moroccan cobra Naja haje venom obtained by gel filtration chromatography possesses the ability to inhibit cancer cells proliferation. More research is needed to identify the specific molecule(s) responsible for the anticancer effect and investigate their mechanism of action.
    Keywords anticancer molecules ; Hepatocellular carcinoma ; multicellular tumor spheroids ; Naja haje ; venom ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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