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  1. Article: Combination of Pulmonary Tractotomy and Free Subcutaneous Fat Pad Coverage for Iatrogenic Lung Injury Caused by Chest Tube Insertion.

    Niman, Eito / Takahashi, Kenji

    Cureus

    2024  Volume 16, Issue 3, Page(s) e56798

    Abstract: Iatrogenic lung injury caused by chest tube insertion is a potential complication that requires careful attention, and thoracic surgeons should be knowledgeable about the appropriate management strategies if complications arise. This report describes a ... ...

    Abstract Iatrogenic lung injury caused by chest tube insertion is a potential complication that requires careful attention, and thoracic surgeons should be knowledgeable about the appropriate management strategies if complications arise. This report describes a successful procedure for treating an iatrogenic lung injury. An 80-year-old Japanese man with severe emphysema complaining of breathlessness was diagnosed with a right secondary pneumothorax. Computed tomography revealed moderate adhesions in the thoracic cavity. Chest tube drainage was performed. Lung expansion was insufficient and massive air leakage continued. Repeat computed tomography showed the chest tube inserted into the right upper lobe. Thus, pulmonary tractotomy followed by free fat pad coverage was performed to successfully treat the iatrogenic lung injury caused by chest tube insertion. Since no air leakage was observed postoperatively, the chest tube was removed on the third postoperative day. The patient was discharged after two weeks of rehabilitation. Pulmonary tractotomy combined with free subcutaneous fat pad coverage would be effective for repairing iatrogenic lung injuries in patients with severe emphysema.
    Language English
    Publishing date 2024-03-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.56798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Ultrasound-Guided Hydrodissection for Sural Neuropathy After Calcaneus Fracture Surgery: A Case Report.

    Omodani, Toru / Takahashi, Kenji

    Cureus

    2023  Volume 15, Issue 10, Page(s) e47749

    Abstract: We present a case study of a 61-year-old man who experienced sural neuropathy following calcaneus fracture surgery, which was effectively treated using ultrasound-guided hydrodissection. Postoperatively, while the patient exhibited good bony fusion, he ... ...

    Abstract We present a case study of a 61-year-old man who experienced sural neuropathy following calcaneus fracture surgery, which was effectively treated using ultrasound-guided hydrodissection. Postoperatively, while the patient exhibited good bony fusion, he reported pain on the lateral side of the calcaneus. Ultrasound findings did not suggest any nerve discontinuity, but localized tenderness around the sural nerve was observed. After hydrodissection using 0.09% lidocaine, the patient's pain significantly decreased. Although hydrodissection alleviated the pain, complete resolution was achieved only post plate removal and neurolysis. This study represents the first report on the efficacy of hydrodissection for postoperative sural neuropathy, suggesting its potential as an effective treatment option.
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.47749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ionic Liquids as Organocatalysts and Solvents for Lignocellulose Reactions.

    Suzuki, Shiori / Takahashi, Kenji

    Chemical record (New York, N.Y.)

    2023  Volume 23, Issue 8, Page(s) e202200264

    Abstract: Ionic liquids (ILs) are the only media that can allow the homogeneous organocatalytic reactions of lignocellulosic biomass (lignocellulose), since the designability of their cations and anions offers the dual functions of solubility and catalytic ... ...

    Abstract Ionic liquids (ILs) are the only media that can allow the homogeneous organocatalytic reactions of lignocellulosic biomass (lignocellulose), since the designability of their cations and anions offers the dual functions of solubility and catalytic activity. This review provides an account of our recent achievements in the organocatalytic approaches for converting lignocellulose into polymer materials based on the principles of IL design that we have originally established. These methodologies include the simple and mild chemical modification of cellulose and lignin under high conversions, with high selectivity, and/or with efficient atom economy. Similar reactions and subsequent fractionation processes are applied to lignocellulose, and a highly productive reaction system is developed using a twin-screw extruder that is specific to the IL media.
    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2044646-9
    ISSN 1528-0691 ; 1527-8999
    ISSN (online) 1528-0691
    ISSN 1527-8999
    DOI 10.1002/tcr.202200264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Involvement of interaction of Cav3.2 and nociceptive TRPA1 in pathological pain transmission.

    Nakagawa, Minami / Takahashi, Kenji / Nishizawa, Yuki / Ohta, Toshio

    Biomedical research (Tokyo, Japan)

    2024  Volume 45, Issue 1, Page(s) 45–55

    Abstract: T-type Ca2+ channels and TRPA1 expressed in sensory neurons are involved in pain. We previously demonstrated a functional interaction of these channels under physiological conditions. Here we investigated the possible involvement of these channels in ... ...

    Abstract T-type Ca2+ channels and TRPA1 expressed in sensory neurons are involved in pain. We previously demonstrated a functional interaction of these channels under physiological conditions. Here we investigated the possible involvement of these channels in inflammatory pain condition. We also evaluated the relationship of these channels endogenously expressed in RIN-14B, a rat pancreatic islet tumor cell line. In dorsal root ganglion (DRG) neurons innervated inflammatory side, [Ca2+]i increases induced by 15 mM KCl (15K) were enhanced in neurons responded to AITC. This enhancement was not observed in genetically TRPA1-deficient neurons. The T-type and AITC-induced currents were larger in neurons of the inflammatory side than in those of the control one. In DRGs of the inflammatory side, the protein expression of Cav3.2, but not TRPA1, was increased. In RIN-14B, 15K-induced [Ca2+]i increases were decreased by blockers of T-type Ca2+ channel and TRPA1, and by TRPA1-silencing. Immunoprecipitation suggested the coexistent of these channels in sensory neurons and RIN-14B. In mice with inflammation, mechanical hypersensitivity was suppressed by blockers of both channels. These data suggest that the interaction of Cav3.2 with TRPA1 in sensory neurons is enhanced via the augmentation of the activities of both channels under inflammatory conditions, indicating that both channels are therapeutic targets for inflammatory pain.
    MeSH term(s) Animals ; Mice ; Rats ; Calcium/metabolism ; Ganglia, Spinal/metabolism ; Isothiocyanates ; Nociception ; Pain/genetics ; Pain/metabolism ; Sensory Receptor Cells/metabolism ; TRPA1 Cation Channel/genetics
    Chemical Substances 2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (62414-75-9) ; Calcium (SY7Q814VUP) ; Isothiocyanates ; TRPA1 Cation Channel ; Cacna1h protein, rat ; Cacna1h protein, mouse ; Trpa1 protein, mouse ; Trpa1 protein, rat
    Language English
    Publishing date 2024-02-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 604561-3
    ISSN 1880-313X ; 0388-6107
    ISSN (online) 1880-313X
    ISSN 0388-6107
    DOI 10.2220/biomedres.45.45
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Facile Separation of Acetic Acid from 1-Ethyl-3-methylimidazolium Acetate Ionic Liquid with the Aid of a Protic Solvent.

    Wada, Naoki / Hara, Takahiro / Takahashi, Kenji

    The journal of physical chemistry. B

    2024  Volume 128, Issue 11, Page(s) 2755–2761

    Abstract: 1-Ethyl-3-methylimidazolium acetate (EmimAc), an excellent solvent for cellulosic biomass, is expected to be utilized in chemical conversion, such as in biomass acetylation with acetic anhydride. The corresponding carboxylic acid, acetic acid (AcH), is ... ...

    Abstract 1-Ethyl-3-methylimidazolium acetate (EmimAc), an excellent solvent for cellulosic biomass, is expected to be utilized in chemical conversion, such as in biomass acetylation with acetic anhydride. The corresponding carboxylic acid, acetic acid (AcH), is quantitatively generated as a byproduct and should be separated from EmimAc for recycling. However, the strong interaction between EmimAc and AcH makes their separation difficult under moderate conditions. This study examined the efficacy of protic solvents in distillation and extraction to weaken this interaction through solvation or hydrogen-bonding interactions. The separation efficiency of AcH from EmimAc via distillation increased as the boiling point of the protic solvent increased. Water addition was more effective than the addition of alcohols with boiling points similar to those of water such as 1-propanol and 2-butanol. Furthermore, the favorable effect of water addition on the extraction of AcH was confirmed using common organic solvents, such as diisopropyl ether, diethyl ether, and ethyl acetate. The partition coefficient (α) of AcH between the aqueous and organic phases increased with an increasing dielectric constant of the organic solvent, whereas the α value of EmimAc decreased. Repeated treatments in both distillation and extraction facilitated the complete separation of AcH from EmimAc.
    Language English
    Publishing date 2024-03-10
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c07225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Freezing treatment under light conditions leads to a dramatic enhancement of freezing tolerance in cold-acclimated Arabidopsis.

    Sugita, Kenji / Takahashi, Shunsuke / Uemura, Matsuo / Kawamura, Yukio

    Plant, cell & environment

    2024  

    Abstract: Overwintering plants survive subzero temperatures by cold acclimation (CA), wherein they acquire freezing tolerance through short-term exposure to low temperatures above 0°C. The freezing tolerance of CA plants increases when they are subsequently ... ...

    Abstract Overwintering plants survive subzero temperatures by cold acclimation (CA), wherein they acquire freezing tolerance through short-term exposure to low temperatures above 0°C. The freezing tolerance of CA plants increases when they are subsequently exposed to mild subzero temperatures, a phenomenon known as second-phase cold hardening (2PH). Here, we explored the molecular mechanism and physiological conditions of 2PH. The results show that, compared with supercooling, a freezing treatment during 2PH after CA enhanced the freezing tolerance of Arabidopsis. This required CA as a pretreatment, and was designated as second-phase freezing acclimation (2PFA). Light increased the effect of 2PFA to enhance freezing tolerance after CA. C-repeat binding factor and cold-regulated genes were downregulated by light during the 2PFA treatment, a different transcription profile from that during CA. The freezing tolerance of 2PFA plants was decreased by the presence of the photosynthetic electron transfer inhibitor 3-(3,4-dichlorophenyl)-1,1-dimethylurea during the 2PFA treatment. Compared with wild-type plants, phototropin1,2 and phyb mutants showed lower freezing tolerance after 2PFA treatment. These results show that exposure to freezing after CA increases freezing tolerance as a secondary process, and that freezing under light conditions further increases freezing tolerance via pathways involving photoreceptors and photosynthetic electron transfer.
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391893-2
    ISSN 1365-3040 ; 0140-7791
    ISSN (online) 1365-3040
    ISSN 0140-7791
    DOI 10.1111/pce.14917
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Electron Transfer Reduction by Hydrogen Creates Porosity in Tantalate Crystals and Produce Multifunctionality.

    Saito, Kenji / Takahashi, Yuma / Kuwabara, Daichi / Watanabe, Yoshiki

    ACS applied materials & interfaces

    2023  Volume 15, Issue 46, Page(s) 53665–53670

    Abstract: Contrary to partially substituted systems, ... ...

    Abstract Contrary to partially substituted systems, WO
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c10246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: In Reply to the Letter to the Editor Regarding "Indication of C2-C7 Cervical Laminoplasty with Muscle and Ligament Preservation in Patients with Kyphosis".

    Iseda, Keiichi / Takahashi, Kenji / Nakajima, Masaaki

    World neurosurgery

    2023  Volume 176, Page(s) 260

    MeSH term(s) Humans ; Laminoplasty ; Kyphosis/surgery ; Lordosis/surgery ; Ligaments/surgery ; Muscles
    Language English
    Publishing date 2023-06-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.05.114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Characteristics of mental disorders among information technology workers in 238 compensated cases in Japan.

    Takahashi, Yuki / Yoshikawa, Toru / Yamamoto, Kenji / Takahashi, Masaya

    Industrial health

    2023  Volume 62, Issue 1, Page(s) 67–76

    Abstract: This study aimed to investigate the circumstances, characteristics, and background factors of mental disorders within the information technology (IT) industry, which is known for the frequent occurrence of mental disorders from overwork and poor ... ...

    Abstract This study aimed to investigate the circumstances, characteristics, and background factors of mental disorders within the information technology (IT) industry, which is known for the frequent occurrence of mental disorders from overwork and poor psychosocial work environment. The study analyzed 238 cases of mental disorders and suicides in the IT industry from fiscal years 2010 to 2018 on the database constructed by the Japan Research Center for Overwork-Related Disorders. The results showed a higher number of cases among men (n=178, 74.8%) and an increasing number among women. The data for diagnosis of mental diseases indicated a high number of depressive episodes (150 cases, 63.0%). Regarding work-induced psychological burden, 37 cases (15.5%) reported "extremely long working hours" for "special events" and 65 cases (27.3%) reported "constantly long working hours". For "specific events", 87 cases (36.6%) reportedly "caused (major) changes in the content and amount of work". Among women, 13 cases (21.7%) of "sexual harassment" (SH), which showed an increasing trend. Therefore, in the IT industry, the working hours must be properly managed. Mental health measures should also accompany improved psychosocial environment in the workplace, and prohibition of SH at work in particular.
    MeSH term(s) Male ; Humans ; Female ; Suicide ; Information Technology ; Japan/epidemiology ; Mental Disorders/epidemiology ; Workplace/psychology
    Language English
    Publishing date 2023-04-13
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 214185-1
    ISSN 1880-8026 ; 0019-8366
    ISSN (online) 1880-8026
    ISSN 0019-8366
    DOI 10.2486/indhealth.2022-0197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Clinical Outcomes of Lateral Lumbar Interbody Fusion with Percutaneous Pedicle Screw for Dialysis-Related Spondyloarthropathy.

    Kitanaka, Shigeyuki / Takatori, Ryota / Tonomura, Hitoshi / Shimizu, Yuichi / Nagae, Masateru / Makinodan, Atsushi / Takahashi, Kenji

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13041089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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