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Article ; Online: Lack of association between the

Khudhur, Zhikal O / Othman, Goran / Othman, Galawezh O / Jafaar, Aziz M / Qadir, Mahdi Kh / Awla, Harem Kh / Qasim, Sara Sh / Hadi, Shayma M / Khan, Samiha S / Noreen, Sobia / Smail, Shukur W

Journal of Taibah University Medical Sciences

2022 Volume 18, Issue 1, Page(s) 162–169

Abstract: Objectives: The genetic polymorphisms of the endothelial nitric oxide synthase (: Methods: Eighty-five healthy subjects and 80 patients with MI admitted to the Erbil Cardiac Centre in the Kurdistan Region of Iraq were enrolled in the study. All ... ...

Abstract	Objectives: The genetic polymorphisms of the endothelial nitric oxide synthase ( Methods: Eighty-five healthy subjects and 80 patients with MI admitted to the Erbil Cardiac Centre in the Kurdistan Region of Iraq were enrolled in the study. All participants were Kurdish from the same ethnic group. The amplification refractory mutation system polymerase chain reaction (ARMS-PCR) was used to determine the rs1800779 (A/G) polymorphism of Results: The genotypic frequencies of the Conclusion: The study concluded that there is a lack of association between the genotypes and alleles of the rs1800779
Language	English
Publishing date	2022-09-05
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	2817396-X
ISSN	1658-3612 ; 1658-3612
ISSN (online)	1658-3612
ISSN	1658-3612
DOI	10.1016/j.jtumed.2022.08.006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A new progestin from fungal transformation of norethisterone and its comparative antimicrobial studies.

Iqbal, Muhammad / Uddin, Aziz / Musharraf, Syed Ghulam / Tauseef, Saima / Samad, Noreen / Khaliq, Saima / Ahmad, Saara

Pakistan journal of pharmaceutical sciences

2022 Volume 35, Issue 2(Special), Page(s) 695–699

Abstract: ... from 1 by using M. phaseolina and P. variotii, respectively. Based on various spectroscopic techniques ...

Abstract	Fungal transformation of a norethisterone (17α-ethynylestra-4-en-17β-ol-3-one) (1) by using Macrophomina phaseolina and Paecilomyces variotii was studied. A new metabolite, 17α-hydroxymethyl-androst-4-en-11β-ol-3-one-17β-acetate (2) with novel changes and a known metabolite, 17α-ethynylestradiol (3) were obtained from 1 by using M. phaseolina and P. variotii, respectively. Based on various spectroscopic techniques, the structures of both metabolites were characterized. The antimicrobial activities of 1-3 were also evaluated. Compound 1 was found to be moderately active against Salmonella paratyphi while 1-3 were almost inactive against other microorganisms.
MeSH term(s)	Anti-Infective Agents/pharmacology ; Biotransformation ; Norethindrone/pharmacology ; Progestins ; Steroids
Chemical Substances	Anti-Infective Agents ; Progestins ; Steroids ; Norethindrone (T18F433X4S)
Language	English
Publishing date	2022-06-06
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	885131-1
ISSN	1011-601X
ISSN	1011-601X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Long-term cancer survivors: research issues and care needs in a key phase of the survivorship spectrum.

Aziz, Noreen M

American journal of hematology

2009 Volume 84, Issue 12, Page(s) 782–784

MeSH term(s)	Adult ; Aged ; Child ; Comorbidity ; Complementary Therapies/psychology ; Complementary Therapies/utilization ; Follow-Up Studies ; Health Knowledge, Attitudes, Practice ; Health Services Needs and Demand/statistics & numerical data ; Humans ; Lymphoma/psychology ; Lymphoma/therapy ; Middle Aged ; Neoplasms/psychology ; Neoplasms/therapy ; Quality of Life ; Research ; Survivors/psychology ; Survivors/statistics & numerical data ; Therapeutics/adverse effects ; Vulnerable Populations
Language	English
Publishing date	2009-12
Publishing country	United States
Document type	Comment ; Editorial
ZDB-ID	196767-8
ISSN	1096-8652 ; 0361-8609
ISSN (online)	1096-8652
ISSN	0361-8609
DOI	10.1002/ajh.21579
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Article ; Online: Role of Pharmacist in Disaster Management: A Quantitative Content Analysis Approach.

Ahmer Raza, Muhammad / Aziz, Shireen / Noreen, Misbah / Masood Raza, Shahid

Innovations in pharmacy

2021 Volume 12, Issue 4

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-09-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2689516-X
ISSN	2155-0417 ; 2155-0417
ISSN (online)	2155-0417
ISSN	2155-0417
DOI	10.24926/iip.v12i4.4359
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Article ; Online: A Portrait of the Pharmacy Profession Globally: Pharmacist Universal Professional Identity and Establishment of Global Pharmacy Council.

Ahmer Raza, Muhammad / Aziz, Shireen / Noreen, Misbah / Anjum, Irfan / Raza, Shahid Masood

Innovations in pharmacy

2022 Volume 13, Issue 1

Abstract: Professional identity is an important component of practice change.⮚ Research on professional identity in pharmacy is limited, and this needs to change if we are to truly move practice in the 21st century.⮚ A unified professional identity is crucial ... ...

Abstract	⮚ Professional identity is an important component of practice change.⮚ Research on professional identity in pharmacy is limited, and this needs to change if we are to truly move practice in the 21st century.⮚ A unified professional identity is crucial for society to see pharmacists as healthcare providers.
Language	English
Publishing date	2022-04-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2689516-X
ISSN	2155-0417 ; 2155-0417
ISSN (online)	2155-0417
ISSN	2155-0417
DOI	10.24926/iip.v13i1.4502
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Article: Biosynthesis of silver nanoparticles from Mukia maderaspatana (L) and their biological activities.

Samad, Noreen / Farooq, Saba / Khaliq, Saima / Ahmed, Saara / Alam, Mehtab / Mustafa, Sana / Uddin, Aziz / Raza, Uzma / Nadeem, Wajahat

Pakistan journal of pharmaceutical sciences

2021 Volume 34, Issue 5(Supplementary), Page(s) 1837–1847

Abstract: ... This study concluded that biosynthesized nanoparticles of Mukia maderaspatna (M.M) plant peels extracts have ...

Abstract	Nanotechnology is a field of science that consists of atoms, molecules and supramolecular molecules that create nanoparticles ranging in size from 1-100nm. Silver nanoparticles are widely used that are considered as effective antimicrobial agents. In this paper, the antioxidant activity of biosynthesized SNPs were analyzed by the DPPPH activity, hydrogen peroxide activity, hydroxyl RSA, TAC, TFC; their results confirmed that the phenolic compounds of this plant peels extracts enhanced the antioxidant and antiglycation activity with respect to silver nanoparticles. Biosynthesized nanoparticles of this plant extracts also showed strong zone of inhibition against the different Xanthomas, Pseudomonas and E. coli. This study concluded that biosynthesized nanoparticles of Mukia maderaspatna (M.M) plant peels extracts have the great biological activities i.e. antiglycation, antioxidant and antibacterial. More research is needed to know the exact dose rate and to compare the different dose combination of the plant with the strong antibiotic agents against these bacteria.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Antioxidants/pharmacology ; Bacteria/drug effects ; Cucurbitaceae/chemistry ; Escherichia coli/drug effects ; Fruit/chemistry ; Green Chemistry Technology ; Metal Nanoparticles/chemistry ; Microbial Sensitivity Tests ; Pakistan ; Particle Size ; Plant Extracts/pharmacology ; Pseudomonas/drug effects ; Silver Compounds/chemistry ; Xanthomonas/drug effects
Chemical Substances	Anti-Bacterial Agents ; Antioxidants ; Plant Extracts ; Silver Compounds
Language	English
Publishing date	2021-11-26
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	885131-1
ISSN	1011-601X
ISSN	1011-601X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Cancer survivorship research: state of knowledge, challenges and opportunities.

Aziz, Noreen M

Acta oncologica (Stockholm, Sweden)

2007 Volume 46, Issue 4, Page(s) 417–432

Abstract: Introduction: Seminal advances in early detection of and treatment strategies for cancer have led to burgeoning numbers of cancer survivors. While most therapeutic modalities for cancer are beneficial and lifesaving, they are associated with adverse ... ...

Abstract	Introduction: Seminal advances in early detection of and treatment strategies for cancer have led to burgeoning numbers of cancer survivors. While most therapeutic modalities for cancer are beneficial and lifesaving, they are associated with adverse long-term and late sequelae. Materials and methods: Literature review using MEDLINE to identify studies examining adverse medical outcomes and post-treatment follow-up care among long-term survivors. Emerging concepts in survivorship research such as definitional issues, research paradigms and methodologic concerns were also examined. Results: Long-term or late adverse sequelae are more prevalent, serious, and persistent than expected in survivors of pediatric and adult cancer, but remain understudied especially among those diagnosed as adults. Follow-up care relevant to survivorship outcomes is neither standardized nor guideline or evidence based for most adult cancers, and optimal practices have yet to be defined. Discussion: Adverse sequelae contribute to burden of illness, health care costs, and decreased length and quality of survival. To-date, very few studies have compared survivor outcomes pre-and post diagnosis. It is critical to examine under-researched questions and understudied survivor groups. Regular follow-up care and monitoring of health status post cancer treatment should 1) permit the timely diagnosis and treatment of adverse outcomes; 2) enable timely diagnosis and treatment of recurrences; 3) facilitate screening and early detection of second cancer(s); 4) allow for detection and management of co-morbidities; and 5) provide the opportunity for preventive strategies such as lifestyle changes. Research findings to-date underscore the need for continued cancer survivorship research that will: inform our understanding of the mechanisms underlying adverse sequelae; lead to the design of less toxic treatments; test the effectiveness of interventions - medical, pharmacologic, and behavioral - that reduce adverse outcomes; test models of post-treatment follow-up care; develop an evidence base for optimal follow-up care practices; and inform survivor and provider decision making.
MeSH term(s)	Age Factors ; Comorbidity/trends ; Continuity of Patient Care ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Neoplasms/therapy ; Radiotherapy/adverse effects ; Research/trends ; Survivors ; Treatment Outcome
Language	English
Publishing date	2007
Publishing country	England
Document type	Journal Article ; Review
ISSN	0284-186X
ISSN	0284-186X
DOI	10.1080/02841860701367878
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Lack of association between the eNOS rs1800779 (A/G) polymorphism and the myocardial infarction incidence among the Iraqi Kurdish population

Zhikal O. Khudhur, MSC / Goran Othman, PhD / Galawezh O. Othman, PhD / Aziz M. Jafaar, MD / Mahdi Kh. Qadir, MSC / Harem Kh. Awla, BSC / Sara Sh. Qasim, BSC / Shayma M. Hadi, BSC / Samiha S. Khan, MBBS / Sobia Noreen, PhD / Shukur W. Smail, MSC

Journal of Taibah University Medical Sciences, Vol 18, Iss 1, Pp 162-

2023 Volume 169

Abstract: الملخص: أهداف البحث: ارتبط تعدد الأشكال الجيني لجين سينثاز أكسيد النيتريك البطاني (إينوس) ارتباطا وثيقا بالعديد من أمراض القلب والأوعية الدموية في مجتمعات مختلفة. هدفت الدراسة الحالية إلى التحقق من ارتباط تعدد الأشكال إينوس مع تقدم احتشاء عضل القلب. طرق ... ...

Abstract	الملخص: أهداف البحث: ارتبط تعدد الأشكال الجيني لجين سينثاز أكسيد النيتريك البطاني (إينوس) ارتباطا وثيقا بالعديد من أمراض القلب والأوعية الدموية في مجتمعات مختلفة. هدفت الدراسة الحالية إلى التحقق من ارتباط تعدد الأشكال إينوس مع تقدم احتشاء عضل القلب. طرق البحث: تم تسجيل خمسة وثمانين شخصا صحيحا وثمانين مريضا بمرض احتشاء عضل القلب تم إدخالهم إلى مركز القلب في أربيل في إقليم كردستان العراق في الدراسة. كان جميع المشاركين أكرادا من نفس المجموعة العرقية. تم استخدام ''تفاعل البلمرة المتسلسل لنظام الطفرة المقاومة للتضخيم'' لتحديد تعدد الأشكال إينوس ومستوى مصل أكسيد النيتريك بواسطة مقياس الطيف الضوئي. النتائج: كانت الترددات النمط الجيني لأنواع إينوس الثلاثة ''أأ'' (النوع البري) و''أج'' و''ج ج'' هي 58.75% و33.75٪ و7.50٪ على التوالي في مرضى احتشاء عضل القلب، وبالنسبة للمجموعة الضابطة كانت 49.41٪ و 43.53٪ و 7.06٪ على التوالي. كما كانت ترددات الأليلات ''أ'' و ''ج'' في مجموعة مرضى احتشاء عضل القلب هي 75.6% و 24.4٪ على التوالي، بينما كانت في المجموعة الضابطة 71.2٪ و 28.8٪ على التوالي. كذلك كشفت النتائج عن عدم وجود ارتباط بين توزيع الأنماط الجينية ومستوى أكسيد النيتريك في مصل الدم مع زيادة خطر الإصابة باحتشاء عضل القلب. الاستنتاجات: خلصت الدراسة إلى عدم وجود ارتباط بين الأنماط الجينية والأليلات لإينوس مع قابلية حدوث احتشاء عضل القلب. Abstract: Objectives: The genetic polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are strongly associated with several cardiovascular diseases (CVDs) in various populations. The current study aimed to investigate the association of the eNOS rs1800779 (A/G) polymorphism with the progress of myocardial infarction (MI). Methods: Eighty-five healthy subjects and 80 patients with MI admitted to the Erbil Cardiac Centre in the Kurdistan Region of Iraq were enrolled in the study. All participants were Kurdish from the same ethnic group. The amplification refractory mutation system polymerase chain reaction (ARMS-PCR) was used to determine the rs1800779 (A/G) polymorphism of eNOS, and the nitric oxide (NO) serum level was detected by spectrophotometer. Results: The genotypic frequencies ...
Keywords	Endothelial nitric oxide synthase ; Kurdish population ; Myocardial infarction ; Nitric oxide ; Polymorphism ; Medicine (General) ; R5-920
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A demographic study on causes of hepatitis transitions among the agricultural community

Bahawal Sana / Abdul Manan / Huma Khan / Muhammad Amjad Bashir / Muhammad Shahid Nisar / Khizer Samiullah / Irum Aziz / Muhammad Farooq / Asma Noreen / Talat Bilal Yasoob / Afrah Fahad Alkhuriji / Nawal M. Al-Malahi / Abdulrahman Alasmari / Mohammed Ali Alshehri / Munaza Batool / Awais Amjad / Sagheer Atta

Journal of King Saud University: Science, Vol 34, Iss 5, Pp 102085- (2022)

2022

Abstract: HCV (Hepatitis virus) has been identified as a foremost cause of long-lasting liver disease and has been linked to severe attacks of cirrhosis and liver cancer. Diabetes is a chronic metabolic disorder that causes abnormal glucose homeostasis. Insulin ... ...

Abstract	HCV (Hepatitis virus) has been identified as a foremost cause of long-lasting liver disease and has been linked to severe attacks of cirrhosis and liver cancer. Diabetes is a chronic metabolic disorder that causes abnormal glucose homeostasis. Insulin resistances (IR) and diabetes can occur at any stage of HCV infection. There are several mechanisms for the development resistance against insulin and diabetic patients with chronic hepatitis C. The study was carried out during year 2109–2020 in the Department of Zoology, Ghazi University, D.G. Khan. The result of the research ware good and matches the findings of other researcher too. Maximum numbers of respondents have never practiced smoking, alcohol, aspirin, urination, fatigue, exercise, hunger and thirst. Diabetic patients have also gone for all type of their diabetes test. While HCV responds were good as maximum number of respondents have done test and they have also stop smoke, alcohol etc.
Keywords	Hepatitis ; Community ; Knowledge ; Science (General) ; Q1-390
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Artificial Intelligence (AI) in Pharmacy: An Overview of Innovations.

Raza, Muhammad Ahmer / Aziz, Shireen / Noreen, Misbah / Saeed, Amna / Anjum, Irfan / Ahmed, Mudassar / Raza, Shahid Masood

Innovations in pharmacy

2022 Volume 13, Issue 2

Abstract: Artificial Intelligence (AI) emerged as an intervention for data and number-related problems. This breakthrough has led to several technological advancements in virtually all fields from engineering to architecture, education, accounting, business, ... ...

Abstract	Artificial Intelligence (AI) emerged as an intervention for data and number-related problems. This breakthrough has led to several technological advancements in virtually all fields from engineering to architecture, education, accounting, business, health, and so on. AI has come a long way in healthcare, having played significant roles in data and information storage and management - such as patient medical histories, medicine stocks, sale records, and so on; automated machines; software and computer applications like diagnostic tools such as MRI radiation technology, CT diagnosis and many more have all been created to aid and simplify healthcare measures. Inarguably, AI has revolutionized healthcare to be more effective and efficient and the pharmacy sector is not left out. During the past few years, a considerable amount of increasing interest in the uses of AI technology has been identified for analyzing as well as interpreting some important fields of pharmacy like drug discovery, dosage form designing, polypharmacology, and hospital pharmacy. Given the growing importance of AI, we wanted to create a comprehensive report which helps every practicing pharmacist understand the biggest breakthroughs which are assisted by the deployment of this field.
Language	English
Publishing date	2022-12-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2689516-X
ISSN	2155-0417 ; 2155-0417
ISSN (online)	2155-0417
ISSN	2155-0417
DOI	10.24926/iip.v13i2.4839
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