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  1. Article ; Online: Angéite givrée : prise en charge diagnostique et thérapeutique à la lumière de l’OCT-angiographie.

    Derrien, S / Titah, C / Vasseur, V / Mauget-Faÿsse, M

    Journal francais d'ophtalmologie

    2022  Volume 45, Issue 9, Page(s) 1103–1105

    Title translation Frosted branch retinal angiitis: Diagnostic and therapeutic management based on OCT-angiography.
    MeSH term(s) Humans ; Tomography, Optical Coherence ; Retinal Vasculitis/therapy ; Retinal Vasculitis/drug therapy ; Fluorescein Angiography
    Language French
    Publishing date 2022-07-19
    Publishing country France
    Document type Journal Article
    ZDB-ID 426662-6
    ISSN 1773-0597 ; 0181-5512
    ISSN (online) 1773-0597
    ISSN 0181-5512
    DOI 10.1016/j.jfo.2022.03.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1417: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Eye Involvement in Wilson's Disease: A Review of the Literature.

    Chevalier, Kevin / Mauget-Faÿsse, Martine / Vasseur, Vivien / Azar, Georges / Obadia, Michaël Alexandre / Poujois, Aurélia

    Journal of clinical medicine

    2022  Volume 11, Issue 9

    Abstract: Wilson's disease (WD) is an autosomal recessive genetic disorder due to a mutation of the ATP7B gene, resulting in impaired hepatic copper excretion and accumulation in various tissues. Ocular findings are one of the hallmarks of the disease. Many ... ...

    Abstract Wilson's disease (WD) is an autosomal recessive genetic disorder due to a mutation of the ATP7B gene, resulting in impaired hepatic copper excretion and accumulation in various tissues. Ocular findings are one of the hallmarks of the disease. Many ophthalmological manifestations have been described and new techniques are currently available to improve their diagnosis and to follow their evolution. We have performed a systematic PubMed search to summarize available data of the recent literature on the most frequent ophthalmological disorders associated with WD, and to discuss the newest techniques used for their detection and follow-up during treatment. In total, 49 articles were retained for this review. The most common ocular findings seen in WD patients are Kayser-Fleischer ring (KFR) and sunflower cataracts. Other ocular manifestations may involve retinal tissue, visual systems and eye mobility. Diagnosis and follow-up under decoppering treatment of these ocular findings are generally easily performed with slit-lamp examination (SLE). However, new techniques are available for the precocious detection of ocular findings due to WD and may be of great value for non-experimented ophthalmologists and non-ophthalmologists practitioners. Among those techniques, anterior segment optical coherence tomography (AS-OCT) and Scheimpflug imaging are discussed.
    Language English
    Publishing date 2022-04-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11092528
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: One-year outcome of neovascular age-related macular degeneration patients followed-up using different optical coherence tomography modalities.

    Sukkarieh, Georges / Vasseur, Vivien / Lejoyeux, Raphaël / Wolff, Benjamin / Mauget-Faÿsse, Martine

    European journal of ophthalmology

    2022  Volume 32, Issue 6, Page(s) 3503–3509

    Abstract: Purpose: The aim of this study is to compare the one year outcome of neovascular age-related macular degeneration (nAMD) patients treated by a PRN regimen of Anti-vascular endothelial growth factor (VEGF) intravitreal injections (IVTs), using optical ... ...

    Abstract Purpose: The aim of this study is to compare the one year outcome of neovascular age-related macular degeneration (nAMD) patients treated by a PRN regimen of Anti-vascular endothelial growth factor (VEGF) intravitreal injections (IVTs), using optical coherence tomography B-scan (OCT-B) or OCT Angiography (OCT-A) imaging modalities during follow-up.
    Methods: Patients older than 50 years with nAMD currently treated by PRN regimen of Anti-VEGF IVTs were recruited from Rothschild Foundation Hospital - Paris and Centre Ophtalmologique Maison Rouge - Strasbourg and followed-up for a year. Patients were randomized in two groups: one group was followed by OCT-B while the other was followed by OCT-A.
    Results: Thirty-three patients were followed by OCT-A and 31 patients were followed by OCT-B. Twenty-nine patients in the OCT-A group and 27 patients in the OCT-B group attended the last visit. No statistically significant difference was found between the two groups at 1 year concerning: improvement or stabilization of the best corrected distance visual acuity (BCVA) (p > 0.9), exudative signs (p > 0.9), number of injections (p = 0.8) and the delay until the first reinjection was performed (p = 0.5).
    Conclusion: The use of OCT-A or OCT-B as imaging modalities in nAMD treated by a PRN regimen of Anti-VEGF IVTs seem to be comparable at one year.
    MeSH term(s) Angiogenesis Inhibitors/therapeutic use ; Endothelial Growth Factors/therapeutic use ; Humans ; Intravitreal Injections ; Macular Degeneration/diagnosis ; Ranibizumab/therapeutic use ; Tomography, Optical Coherence/methods ; Treatment Outcome ; Vascular Endothelial Growth Factor A ; Visual Acuity ; Wet Macular Degeneration/diagnosis ; Wet Macular Degeneration/drug therapy
    Chemical Substances Angiogenesis Inhibitors ; Endothelial Growth Factors ; Vascular Endothelial Growth Factor A ; Ranibizumab (ZL1R02VT79)
    Language English
    Publishing date 2022-03-14
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721221088260
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3342: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Acute syphilitic posterior placoid chorioretinopathy presenting as atypical multiple evanescent white dot syndrome.

    Azar, Georges / Wolff, Benjamin / Azam, Stéphane / Mauget-Faÿsse, Martine

    European journal of ophthalmology

    2020  Volume 31, Issue 2, Page(s) NP141–NP144

    Abstract: Background: This paper reports the case of a young man who presented with syphilis masquerading as multiple evanescent white dots syndrome (MEWDS), which turned out to be an acute syphilitic posterior placoid chorioretinopathy (ASPPC) during follow-up.!# ...

    Abstract Background: This paper reports the case of a young man who presented with syphilis masquerading as multiple evanescent white dots syndrome (MEWDS), which turned out to be an acute syphilitic posterior placoid chorioretinopathy (ASPPC) during follow-up.
    Case presentation: A 59-year-old healthy male consulted for a three days' history of visual impairment in both eyes. On multimodal imaging, he was diagnosed as MEWDS. Fundus fluorescein angiography (FFA) showed early peripheral bilateral granular hyperfluorescence that correlated with the yellow-white dots found on fundus exam. Indocyanine green angiography (ICGA) depicted hypofluorescent dots on late phase. Spectral-domain optical coherence tomography (SD-OCT) revealed numerous inner retinal highly reflective deposits in the outer nuclear layer and disruption of the ellipsoid zone. After initial improvement, he presented again for a sudden visual loss at 3 weeks. FFA, ICGA and SD-OCT demonstrated the same but more numerous and outer lesions suggesting an ASPPC. A full inflammatory work-up revealed highly positive titers of rapid plasma regain (RPR) and fluorescent treponemal antibody absorption (FTA-Abs), suggesting a syphilis infection. The ophthalmological manifestations dramatically improved after the patient was admitted for high-dose intravenous penicillin G 24 million per day for 2 weeks.
    Conclusion: This is the first case that reports an ocular syphilitic infection masquerading as MEWDS at presentation and that turns to be an ASPPC. Syphilis serology should be routinely done in every case of atypical MEWDS especially when unusually presented in a young healthy man, with bilateral involvement and a bad clinical evolution.
    MeSH term(s) Acute Disease ; Anti-Bacterial Agents/therapeutic use ; Chorioretinitis/diagnosis ; Chorioretinitis/drug therapy ; Chorioretinitis/microbiology ; Coloring Agents/administration & dosage ; Eye Infections, Bacterial/diagnosis ; Eye Infections, Bacterial/drug therapy ; Eye Infections, Bacterial/microbiology ; Fluorescein Angiography/methods ; Humans ; Indocyanine Green/administration & dosage ; Infusions, Intravenous ; Male ; Middle Aged ; Multimodal Imaging/methods ; Penicillin G/therapeutic use ; Syphilis/diagnosis ; Syphilis/drug therapy ; Syphilis/microbiology ; Tomography, Optical Coherence ; Visual Acuity/physiology ; White Dot Syndromes/diagnosis ; White Dot Syndromes/drug therapy ; White Dot Syndromes/microbiology
    Chemical Substances Anti-Bacterial Agents ; Coloring Agents ; Indocyanine Green (IX6J1063HV) ; Penicillin G (Q42T66VG0C)
    Language English
    Publishing date 2020-09-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/1120672120957589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3342: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Variation of choroidal thickness in diabetic macular edema: friend or foe?

    Mathis, Thibaud / Dot, Corinne / Mauget-Faÿsse, Martine / Kodjikian, Laurent

    Acta ophthalmologica

    2020  Volume 99, Issue 2, Page(s) e282–e283

    MeSH term(s) Choroid/pathology ; Diabetic Retinopathy/complications ; Diabetic Retinopathy/diagnosis ; Fluorescein Angiography/methods ; Fundus Oculi ; Humans ; Macular Edema/diagnosis ; Macular Edema/etiology ; Tomography, Optical Coherence/methods
    Language English
    Publishing date 2020-06-26
    Publishing country England
    Document type Letter
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/aos.14530
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    Ul I Zs.90: Show issues Location:
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  6. Article ; Online: Incidence and clinical significance of fovea plana in the French population with age-related cataract.

    Lejoyeux, R / Bonnin, S / Guindolet, D / Jacquiod, B / Erol, O / Le Mer, Y / Jeguirim, H / Mauget-Faÿsse, M / Tadayoni, R

    European journal of ophthalmology

    2022  Volume 33, Issue 4, Page(s) 1683–1686

    Abstract: Background: Fovea plana is defined as an immature macula diagnosed by OCT, showing the unusual shunt of the inner retinal layers into the fovea. The incidence of fovea plana in the adult population remains to be determined. The aim of this study was to ... ...

    Abstract Background: Fovea plana is defined as an immature macula diagnosed by OCT, showing the unusual shunt of the inner retinal layers into the fovea. The incidence of fovea plana in the adult population remains to be determined. The aim of this study was to determine the incidence of fovea plana in the French population with age-related cataract.
    Methods: Consecutive patients who underwent cataract surgery in Rothschild Foundation Hospital, France, between January and March 2021, with preoperative analyzable OCT scans available, were retrospectively screened in order to determine the incidence of fovea plana in these population. Ophthalmological characteristics of patients were reported, and detailed.
    Result: Fovea plana was encountered in 20 out of 204 patients during the 3 months corresponding to an incidence of 9.8%. One of those patients had stage 2 fovea plana.
    Conclusion: Although fovea plana is defined as an immature macula, it is not rare in preoperative population. This macular aspect was not associated with poor visual acuity in our cohort.
    MeSH term(s) Adult ; Humans ; Incidence ; Retrospective Studies ; Clinical Relevance ; Tomography, Optical Coherence/methods ; Visual Acuity ; Fovea Centralis ; Cataract/diagnosis ; Cataract/epidemiology ; Vitrectomy/methods
    Language English
    Publishing date 2022-12-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/11206721221149067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3342: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: COMPARISON OF PRIMARY AND SECONDARY FORMS OF MULTIPLE EVANESCENT WHITE DOT SYNDROME.

    Serrar, Yasmine / Cahuzac, Armelle / Gascon, Pierre / Langlois-Jacques, Carole / Mauget-Faÿsse, Martine / Wolff, Benjamin / Sève, Pascal / Kodjikian, Laurent / Mathis, Thibaud

    Retina (Philadelphia, Pa.)

    2022  Volume 42, Issue 12, Page(s) 2368–2378

    Abstract: Purpose: The aim of this study was to compare primary versus secondary forms of multiple evanescent white dot syndrome (MEWDS) at T0 (baseline) and T1 (1-4 months after the onset of symptoms).: Methods: A total of 101 eyes in 100 patients were ... ...

    Abstract Purpose: The aim of this study was to compare primary versus secondary forms of multiple evanescent white dot syndrome (MEWDS) at T0 (baseline) and T1 (1-4 months after the onset of symptoms).
    Methods: A total of 101 eyes in 100 patients were included in a multicentric retrospective study.
    Results: Secondary MEWDS was defined as MEWDS associated with underlying chorioretinal inflammatory pathologies, mainly multifocal choroiditis and punctuate inner choroidopathy. Patients with secondary MEWDS were older (P = 0.011). The proportion of women (P = 0.8), spherical equivalent (P = 0.3), and best-corrected visual acuity at T0 (P = 0.2) were not significantly different between the two groups. The area of MEWDS lesions on late-phase indocyanine green angiography was significantly smaller in secondary MEWDS (P = 0.001) and less symmetrical with respect to both horizontal (P = 0.003) and vertical (P = 0.004) axis. At T0, neither the clinical (P = 0.5) nor the multimodal imaging (P = 0.2) inflammation scores were significantly different between the groups. At T1, the multimodal imaging inflammation score was higher in secondary MEWDS (P = 0.021).
    Conclusion: In secondary MEWDS, outer retinal lesions are less extensive and located close to preexisting chorioretinal lesions. Mild signs of intraocular inflammation on multimodal imaging are more frequent in secondary MEWDS during recovery. These findings suggest that chorioretinal inflammation may trigger secondary MEWDS.
    MeSH term(s) Humans ; Female ; Fluorescein Angiography/methods ; Retrospective Studies ; White Dot Syndromes/diagnosis ; Multifocal Choroiditis ; Inflammation
    Language English
    Publishing date 2022-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000003609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1724: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: HAIR DYE-INDUCED RETINOPATHY MIMICKING MEK-INHIBITOR RETINOPATHY.

    Faure, Céline / Salamé, Nabil / Cahuzac, Armelle / Mauget-Faÿsse, Martine / Scemama, Claire

    Retinal cases & brief reports

    2020  Volume 16, Issue 3, Page(s) 329–332

    Abstract: Purpose: To report a new toxic retinopathy related to the use of hair dye.: Methods: Case reports of three patients with follow-up after exposure and until resolution.: Results: There were three middle-aged women (32-66 year old) all of whom had ... ...

    Abstract Purpose: To report a new toxic retinopathy related to the use of hair dye.
    Methods: Case reports of three patients with follow-up after exposure and until resolution.
    Results: There were three middle-aged women (32-66 year old) all of whom had bilateral moderate to severe vision loss and normal slit-lamp examination at presentation. Fundus examination showed bilateral multiple serous retinal detachments predominantly located in the posterior pole, with some pigment epithelial hypertrophy in chronic cases. Optical coherence tomography showed similar features as in MEK-inhibitor retinopathy. Electrooculogram performed in one patient showed abnormal Arden ratio. During follow-up, visual acuity improved with regression of the serous retinal detachments. The speed of resolution was proportional to the acuteness of the exposure to aromatic amines.
    Conclusion: Hair dyes containing aromatic amines can be responsible for bilateral toxic retinopathy mimicking MEK-inhibitor retinopathy.
    MeSH term(s) Adult ; Aged ; Amines/adverse effects ; Female ; Fluorescein Angiography ; Hair Dyes/adverse effects ; Humans ; Middle Aged ; Mitogen-Activated Protein Kinase Kinases/adverse effects ; Protein Kinase Inhibitors/adverse effects ; Retinal Detachment/diagnosis ; Retinal Diseases/chemically induced ; Retinal Diseases/complications ; Retinal Diseases/diagnosis ; Tomography, Optical Coherence
    Chemical Substances Amines ; Hair Dyes ; Protein Kinase Inhibitors ; Mitogen-Activated Protein Kinase Kinases (EC 2.7.12.2)
    Language English
    Publishing date 2020-01-16
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000000969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Optical Coherence Tomography Angiography Analysis of Retinal and Choroidal Vascular Networks during Acute, Relapsing, and Quiescent Stages of Macular Toxoplasma Retinochoroiditis.

    Azar, Georges / Favard, Catherine / Salah, Sawsen / Brézin, Antoine / Vasseur, Vivien / Mauget-Faÿsse, Martine

    BioMed research international

    2020  Volume 2020, Page(s) 4903735

    Abstract: Purpose: To highlight the advantages of optical coherence tomography angiography (OCTA) in delineating the morphological features of the retinal and choroidal vascular network during acute, relapsing, and quiescent stages of macular toxoplasma ... ...

    Abstract Purpose: To highlight the advantages of optical coherence tomography angiography (OCTA) in delineating the morphological features of the retinal and choroidal vascular network during acute, relapsing, and quiescent stages of macular toxoplasma retinochoroiditis.
    Methods: This prospective study included patients presenting with both active and quiescent ocular toxoplasmoses. OCTA was obtained to diagnose and follow the subsequent vascular network changes at diagnosis and six months after acute presentation.
    Results: Twenty-three eyes of 23 patients were included. In active lesions, OCTA showed extensive, well-delineated areas of intense hyposignal and perifoveal capillary arcade disruption in the parafoveal superficial capillary plexus (pSCP) and less extensive hyposignal in the parafoveal deep capillary plexus (pDCP). Signals of decreased deep capillary density and disorganization were also seen in the choroid. In nonactive lesions, OCTA demonstrated a homogenous and equally attenuated grayish hyposignal of the pSCP and pDCP and a partial restoration of the nonperfused choroidal areas.
    Conclusion: OCTA is a useful technique for vascular network analysis in toxoplasma retinochoroiditis. It allows the visualization of the different network changes and behaviors during the different stages of the infection.
    MeSH term(s) Adult ; Capillaries/parasitology ; Capillaries/pathology ; Choroid/parasitology ; Choroid/pathology ; Female ; Fluorescein Angiography/methods ; Humans ; Male ; Microvessels/parasitology ; Microvessels/pathology ; Prospective Studies ; Retina/parasitology ; Retina/pathology ; Retinal Vessels/parasitology ; Retinal Vessels/pathology ; Tomography, Optical Coherence/methods ; Toxoplasma/pathogenicity ; Toxoplasmosis, Ocular/parasitology ; Toxoplasmosis, Ocular/pathology ; Visual Acuity/physiology
    Language English
    Publishing date 2020-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2020/4903735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Atypical Foveal Hypoplasia in Best Disease.

    Moret, Emmanuelle / Lejoyeux, Raphaël / Bonnin, Sophie / Azar, Georges / Guillaume, Jessica / Le Cossec, Chloé / Lafolie, Justine / Alonso, Anne-Sophie / Favard, Catherine / Meunier, Isabelle / Vasseur, Vivien / Mauget-Faÿsse, Martine

    Journal of personalized medicine

    2023  Volume 13, Issue 2

    Abstract: Purpose: To determine the prevalence and characteristics of foveal hypoplasia (also called fovea plana) in patients with Best disease using spectral-domain (SD) optical coherence tomography (OCT) and OCT-angiography (OCT-A).: Design: A retrospective ... ...

    Abstract Purpose: To determine the prevalence and characteristics of foveal hypoplasia (also called fovea plana) in patients with Best disease using spectral-domain (SD) optical coherence tomography (OCT) and OCT-angiography (OCT-A).
    Design: A retrospective observational study including patients diagnosed with Best disease.
    Subjects and participants: Fifty-nine eyes of thirty-two patients (fifteen females (46.9%) and seventeen males (53.1%),
    Methods and main outcome measures: Cross-sectional OCT images were assessed for the persistence of inner retinal layers (IRL) and OCT-A was analyzed for the presence of a foveal avascular zone (FAZ), the size of which was determined when applicable.
    Results: Overall, 16 eyes (27.1%) of 9 patients had a fovea plana appearance ('FP group') with the persistence of IRL, and 43 eyes (72.9%) of 23 patients did not have fovea plana appearance ('no FP group'). Among FP eyes, OCT-A performed in 13 eyes showed bridging vessels through the FAZ in 100% of eyes with OCT-A. Using Thomas classification, 14 out of the 16 eyes with fovea plana (87.5%) had atypical foveal hypoplasia, and the 2 others (12.5%) had a grade 1b fovea plana.
    Conclusion: In our series, foveal hypoplasia was present in 27.1% of patients with Best disease. OCT-A showed bridging vessels through the FAZ in all eyes. These findings highlight the microvascular changes associated with Best disease, which can be an early sign of the disease in patients with a family history.
    Language English
    Publishing date 2023-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13020337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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