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  1. Article ; Online: Increasing demand for ophthalmic pathology: time trends in a laboratory with nationwide coverage.

    Stålhammar, Gustav / Lardner, Emma / Georgsson, Marianne / Seregard, Stefan

    BMC ophthalmology

    2023  Volume 23, Issue 1, Page(s) 88

    Abstract: Purpose: To report the time trends in basic patient characteristics and the number of specimens received at a national referral center for ophthalmic pathology.: Methods: Data on patient sex, age at surgical resection and geographical location of the ...

    Abstract Purpose: To report the time trends in basic patient characteristics and the number of specimens received at a national referral center for ophthalmic pathology.
    Methods: Data on patient sex, age at surgical resection and geographical location of the referring unit were obtained for all specimens received at the St. Erik Ophthalmic Pathology laboratory, Stockholm, Sweden, between January 1
    Results: A total of 33 057 specimens had been received, of which 14 560 (44%) came from men and 18 477 (56%) from women (for 20 patients, the sex was not specified). The average annual percent change (AAPC) in the number specimens received was + 10.5%, whereas the Swedish population increased with 0.5% per year. Patients became older throughout the period, with an average yearly increase of patient age at surgery of 0.3 years (AAPC 0.2%). Overall, women were three years older than men at surgery (59.4 versus 56.4 years, P < 0.0001) The number of specimens increased with patient age from the first to the 8
    Conclusions: During six decades, the growth in number of specimens sent to our national referral center for ophthalmic pathology has greatly outpaced the growth of the population, indicating an increasing demand for subspecialized services. Throughout the period, patients have become older, and a higher number of specimens have been submitted from female patients.
    MeSH term(s) Male ; Female ; Humans ; Infant ; Face ; Eye ; Referral and Consultation ; Sweden/epidemiology
    Language English
    Publishing date 2023-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050436-6
    ISSN 1471-2415 ; 1471-2415
    ISSN (online) 1471-2415
    ISSN 1471-2415
    DOI 10.1186/s12886-023-02828-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: EJO talks to Stefan Seregard, President of the European Society of Ophthalmology, about the SOE 2015 congress and what makes the SOE congress so unique.

    Seregard, Stefan

    European journal of ophthalmology

    2015  Volume 25, Issue 2, Page(s) 80

    MeSH term(s) Austria ; Congresses as Topic ; Humans ; Ophthalmology/organization & administration ; Societies, Medical
    Language English
    Publishing date 2015-03
    Publishing country Italy
    Document type Interview
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Nordic Ophthalmological Congress revisits Stockholm.

    Seregard, Stefan

    Acta ophthalmologica

    2014  Volume 92, Issue 4, Page(s) 303–304

    MeSH term(s) Congresses as Topic/organization & administration ; Humans ; Ophthalmology/organization & administration ; Sweden
    Language English
    Publishing date 2014-06
    Publishing country England
    Document type Editorial
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/aos.12451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Eye Symptoms in a Patient With Prostate Cancer.

    Kairemo, Kalevi / Kangasmäki, Aki / Joensuu, Timo / Seregard, Stefan

    Clinical nuclear medicine

    2020  Volume 45, Issue 5, Page(s) 370–371

    Abstract: A 66-year-old man with castration-resistant prostate cancer was evaluated with F-prostate-specific membrane antigen (PSMA) 1007 PET/CT, which revealed extensive PSMA-positive skeletal metastases in the skull, thorax, spine, pelvis, and extremities. He ... ...

    Abstract A 66-year-old man with castration-resistant prostate cancer was evaluated with F-prostate-specific membrane antigen (PSMA) 1007 PET/CT, which revealed extensive PSMA-positive skeletal metastases in the skull, thorax, spine, pelvis, and extremities. He was then treated Lu-PSMA-617 therapy. Twenty-four-hour SPECT/CT revealed additional activity not seen with F-PSMA adjacent to his left eye. The lesion was biopsied after the first cycle due to pain. This activity was not visible on SPECT/CT after the second treatment cycle, and his eye pain has resolved.
    MeSH term(s) Aged ; Dipeptides ; Eye Neoplasms/diagnostic imaging ; Eye Neoplasms/secondary ; Heterocyclic Compounds, 1-Ring ; Humans ; Male ; Prostatic Neoplasms, Castration-Resistant/diagnostic imaging ; Prostatic Neoplasms, Castration-Resistant/pathology ; Radiopharmaceuticals ; Single Photon Emission Computed Tomography Computed Tomography
    Chemical Substances 177Lu-PSMA-617 ; Dipeptides ; Heterocyclic Compounds, 1-Ring ; Radiopharmaceuticals
    Language English
    Publishing date 2020-03-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000002982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Presenting Symptoms Are Associated with Uveal Melanoma-Related Death.

    Fili, Maria / Seregard, Stefan / Stålhammar, Gustav

    Ophthalmology

    2020  Volume 128, Issue 7, Page(s) 1107–1109

    MeSH term(s) Aged ; Brachytherapy ; Female ; Follow-Up Studies ; Humans ; Macula Lutea/diagnostic imaging ; Male ; Melanoma/diagnosis ; Melanoma/mortality ; Melanoma/radiotherapy ; Middle Aged ; Optic Disk/diagnostic imaging ; Retrospective Studies ; Survival Rate/trends ; Sweden/epidemiology ; Uveal Neoplasms/diagnosis ; Uveal Neoplasms/mortality ; Uveal Neoplasms/radiotherapy ; Visual Fields/physiology
    Language English
    Publishing date 2020-11-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2020.11.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Gullstrand's Nobel Prize. 100 years and counting.

    Seregard, Stefan

    Acta ophthalmologica

    2011  Volume 89, Issue 8, Page(s) 699–700

    MeSH term(s) Anniversaries and Special Events ; History, 19th Century ; History, 20th Century ; Humans ; Nobel Prize ; Ophthalmology/history ; Refraction, Ocular ; Sweden
    Language English
    Publishing date 2011-12
    Publishing country England
    Document type Biography ; Editorial ; Historical Article
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/j.1755-3768.2011.02333.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A serum protein signature at the time of Uveal Melanoma diagnosis predicts long-term patient survival.

    Herrspiegel, Christina / Plastino, Flavia / Lardner, Emma / Seregard, Stefan / Williams, Pete A / André, Helder / Stålhammar, Gustav

    BMC cancer

    2023  Volume 23, Issue 1, Page(s) 277

    Abstract: Purpose: To develop a prognostic test based on a single blood sample obtained at the time of uveal melanoma diagnosis.: Methods: 83 patients diagnosed with posterior uveal melanoma between 1996 and 2000 were included. Peripheral serum samples were ... ...

    Abstract Purpose: To develop a prognostic test based on a single blood sample obtained at the time of uveal melanoma diagnosis.
    Methods: 83 patients diagnosed with posterior uveal melanoma between 1996 and 2000 were included. Peripheral serum samples were obtained at diagnosis and kept at -80 °C until this analysis. Protein profiling of 84 cancer-related proteins was used to screen for potential biomarkers and a prognostic test that stratifies patients into metastatic risk categories was developed (serUM-Px) in a training cohort and then tested in a validation cohort.
    Results: Low serum leptin levels and high osteopontin levels were found to identify patients with poor prognosis and were therefore selected for inclusion in the final test. In the validation cohort, patient sex and American Joint Committee on Cancer stages were similarly distributed between the low, intermediate, and high metastatic risk categories. With increasing metastatic risk category, patients had shorter metastasis-free- and overall survival, as well as greater cumulative incidence of uveal melanoma-related mortality in competing risk analysis (P = 0.007, 0.018 and 0.029, respectively). In multivariate Cox regression, serUM-Px was an independent predictor of metastasis with tumor size and patient sex as covariates (hazard ratio 3.2, 95% CI 1.5-6.9).
    Conclusions: A prognostic test based on a single peripheral venous blood sample at the time of uveal melanoma diagnosis stratifies patients into low, intermediate, and high metastatic risk categories. Prospective validation will facilitate its clinical utility.
    MeSH term(s) Humans ; Survival Rate ; Prognosis ; Uveal Neoplasms/pathology ; Blood Proteins
    Chemical Substances Blood Proteins
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-023-10757-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: HSAN-beslut hot mot svensk ogonsjukvård.

    Seregard, Stefan

    Lakartidningen

    2009  Volume 106, Issue 35, Page(s) 2153–2154

    Title translation HSAN decision a threat against Swedish ophthalmologic care.
    MeSH term(s) Choroidal Neovascularization/diagnosis ; Emergencies ; Fluorescein Angiography ; Humans ; Macular Degeneration/diagnosis ; Malpractice ; Ophthalmology ; Practice Patterns, Physicians'
    Language Swedish
    Publishing date 2009-08
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 391010-6
    ISSN 1652-7518 ; 0023-7205
    ISSN (online) 1652-7518
    ISSN 0023-7205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Who's the faster runner: the cheetah or the rabbit?

    Seregard, Stefan

    Acta ophthalmologica

    2009  Volume 87, Issue 2, Page(s) 148

    MeSH term(s) Conjunctival Neoplasms/mortality ; Conjunctival Neoplasms/pathology ; Humans ; Melanoma/mortality ; Melanoma/pathology ; Uveal Neoplasms/mortality ; Uveal Neoplasms/pathology
    Language English
    Publishing date 2009-03
    Publishing country England
    Document type Comment ; Comparative Study ; Editorial
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/j.1755-3768.2008.01334.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: To biopsy or not to biopsy?

    Seregard, Stefan

    Acta ophthalmologica

    2009  Volume 87, Issue 6, Page(s) 586–587

    MeSH term(s) Biopsy, Needle/adverse effects ; Biopsy, Needle/standards ; Diagnostic Techniques, Ophthalmological/standards ; Eye/pathology ; Eye Neoplasms/pathology ; Humans ; Melanoma/diagnosis ; Uveal Neoplasms/diagnosis
    Language English
    Publishing date 2009-09
    Publishing country England
    Document type Editorial ; Evaluation Studies
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/j.1755-3768.2009.01638.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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