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  1. Article ; Online: Hypoplastic Circumflex Aorta With Anomalous Left Pulmonary Artery: Uncrossing Operation in a Neonate.

    Alloah, Qais / Misra, Nilanjana / Kwon, Elena / Jhaveri, Simone / Rajagopal, Hari / Gasparis, Christopher / Meyer, David B

    World journal for pediatric & congenital heart surgery

    2024  , Page(s) 21501351241237955

    Abstract: Circumflex aortic arch with coarctation and anomalous origin of the left pulmonary artery from the aorta are rare cardiovascular anomalies. These conditions can lead to early pulmonary hypertension and challenging management. Early diagnosis and surgical ...

    Abstract Circumflex aortic arch with coarctation and anomalous origin of the left pulmonary artery from the aorta are rare cardiovascular anomalies. These conditions can lead to early pulmonary hypertension and challenging management. Early diagnosis and surgical intervention are beneficial for optimal outcome. We present a case where both anomalies coexisted and were repaired with aortic uncrossing, arch augmentation, and reimplantation of the left pulmonary artery. To our knowledge, this is the first documented instance of these anomalies coexisting and being repaired in the neonatal period.
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2550261-X
    ISSN 2150-136X ; 2150-1351
    ISSN (online) 2150-136X
    ISSN 2150-1351
    DOI 10.1177/21501351241237955
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  2. Article ; Online: Association and Repair of Right Aortic Arch With Aberrant Left Subclavian Artery With Subclavian Stenosis.

    Cheong, Daniel / Jhaveri, Simone / Smerling, Jonathan / Rajagopal, Hari / Misra, Nilanjana / Meyer, David B

    World journal for pediatric & congenital heart surgery

    2023  Volume 15, Issue 1, Page(s) 133–136

    Abstract: Surgical repair of right aortic arch and aberrant left subclavian artery has traditionally involved ligamentum division. Such patients can have stenosis at the origin of the aberrant subclavian artery either at the time of presentation or later. The more ...

    Abstract Surgical repair of right aortic arch and aberrant left subclavian artery has traditionally involved ligamentum division. Such patients can have stenosis at the origin of the aberrant subclavian artery either at the time of presentation or later. The more recently popularized repair involving resection of Kommerell diverticulum with transfer of the subclavian artery to the left carotid artery allows resection of the stenotic segment and serves as an effective treatment for subclavian stenosis as well. We present three cases of early repair of this arch anomaly with associated subclavian stenosis repaired successfully in that manner.
    MeSH term(s) Humans ; Subclavian Artery/diagnostic imaging ; Subclavian Artery/surgery ; Subclavian Artery/abnormalities ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Aorta, Thoracic/abnormalities ; Constriction, Pathologic ; Diverticulum/complications ; Diverticulum/diagnostic imaging ; Diverticulum/surgery ; Cardiovascular Abnormalities/complications ; Cardiovascular Abnormalities/diagnostic imaging ; Cardiovascular Abnormalities/surgery ; Heart Defects, Congenital/complications
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2550261-X
    ISSN 2150-136X ; 2150-1351
    ISSN (online) 2150-136X
    ISSN 2150-1351
    DOI 10.1177/21501351231194256
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  3. Article ; Online: Fetal Echocardiographic Variables Associated with Pre-Surgical Mortality in Truncus Arteriosus: A Pilot Study.

    Cox, Kelly / Husain, Nazia / Jhaveri, Simone / Geiger, Miwa / Berhane, Haben / Patel, Sheetal

    Pediatric cardiology

    2023  Volume 44, Issue 6, Page(s) 1397–1405

    Abstract: Truncus arteriosus (TA) is a rare congenital heart defect that can be prenatally detected by fetal echocardiography. However, prognostication and prenatal counseling focus primarily on surgical outcomes due to limited fetal and neonatal pre-surgical ... ...

    Abstract Truncus arteriosus (TA) is a rare congenital heart defect that can be prenatally detected by fetal echocardiography. However, prognostication and prenatal counseling focus primarily on surgical outcomes due to limited fetal and neonatal pre-surgical mortality data. We aimed to describe the incidence and identify predictors of pre-surgical mortality in prenatally detected TA. This two-center, retrospective cohort study included fetuses diagnosed with TA between 01/2010 and 04/2020. The primary outcome was pre-surgical mortality, defined by fetal or neonatal pre-surgical death or primary listing for transplantation prior to discharge. Univariable regression modeling, Chi-square tests, and t tests assessed for associations between prenatal clinical, demographic, and fetal echocardiographic (fetal-echo) variables and pre-surgical mortality. Of 23 pregnancies with prenatal diagnosis of TA, 4 (17%) were terminated. Of the remaining 19, pre-surgical mortality occurred in 4 (26%), including 2 (11%) fetal deaths and 2 (11%) neonatal pre-surgical deaths. No transplantation listings. Of liveborn fetuses (n = 17), 15 (88%) underwent a neonatal surgery, and 1 (6%) required ECMO. As compared to the survivors, the pre-surgical mortality group had a higher likelihood of having left ventricular dysfunction (0% vs. 40%; p = 0.01), right ventricular dysfunction (0% vs. 60%; p = 0.002), cardiovascular profile score < 7 (0% vs. 40%; p = 0.01), skin edema (0% vs. 40%; p = 0.01), and abnormal umbilical venous (UV) Doppler (0% vs. 60%; p = 0.002). The presence of truncal valve regurgitation or stenosis neared significance. In this cohort with prenatally diagnosed TA, there is significant pre-surgical mortality, including fetal death and neonatal pre-surgical death. Termination rate is also high. Fetal-echo variables associated with pre-surgical mortality in this cohort include ventricular dysfunction, low CVP, skin edema, and abnormal UV Doppler. Knowledge about prenatal risk factors for pre-surgical mortality may guide parental counseling and postnatal planning in prenatally diagnosed TA.
    MeSH term(s) Pregnancy ; Infant, Newborn ; Female ; Humans ; Truncus Arteriosus ; Pilot Projects ; Retrospective Studies ; Truncus Arteriosus, Persistent/surgery ; Echocardiography ; Ultrasonography, Prenatal
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 800857-7
    ISSN 1432-1971 ; 0172-0643
    ISSN (online) 1432-1971
    ISSN 0172-0643
    DOI 10.1007/s00246-023-03099-9
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1528: Show issues Location:
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  4. Article: Expanding the electrical phenotype of

    Jhaveri, Simone / Aziz, Peter F / Saarel, Elizabeth

    HeartRhythm case reports

    2018  Volume 4, Issue 11, Page(s) 530–533

    Language English
    Publishing date 2018-08-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2018.08.001
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  5. Article ; Online: Biliary Complications of Prolonged Ceftriaxone Use in Patients With Intracranial Infections.

    Naureckas Li, Caitlin / Parzen-Johnson, Simon / Jhaveri, Ravi

    Journal of the Pediatric Infectious Diseases Society

    2023  Volume 12, Issue 6, Page(s) 379–380

    MeSH term(s) Humans ; Ceftriaxone/adverse effects ; Brain Diseases/drug therapy ; Infections/drug therapy ; Biliary Tract/drug effects
    Chemical Substances Ceftriaxone (75J73V1629)
    Language English
    Publishing date 2023-06-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2668791-4
    ISSN 2048-7207 ; 2048-7193
    ISSN (online) 2048-7207
    ISSN 2048-7193
    DOI 10.1093/jpids/piad036
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  6. Article: Hammock effect and complete cusp prolapse: Rare mechanisms of Melody valve failure demonstrated by intracardiac echocardiography.

    Jhaveri, Simone / Prieto, Lourdes / Suntharos, Patcharapong

    Annals of pediatric cardiology

    2019  Volume 12, Issue 3, Page(s) 342–344

    Abstract: Transcatheter pulmonary valve replacement using Melody valve (Medtronic, Minneapolis MN) has significantly increased in the recent decades. Melody valve failures, although rare, can be problematic and require re-intervention. Through intracardiac ... ...

    Abstract Transcatheter pulmonary valve replacement using Melody valve (Medtronic, Minneapolis MN) has significantly increased in the recent decades. Melody valve failures, although rare, can be problematic and require re-intervention. Through intracardiac echocardiography, we present two patients who each had a rare etiology for dysfunction of their Melody valve. Hammock effect, wherein the valve does not oppose the stent and complete cusp failure causing severe regurgitation have not been previously described as causes of Melody valve failure in the absence of endocarditis. Awareness and knowledge of these mechanisms is pivotal in the management of this patient population.
    Language English
    Publishing date 2019-08-13
    Publishing country India
    Document type Case Reports
    ZDB-ID 2430956-4
    ISSN 0974-5149 ; 0974-2069
    ISSN (online) 0974-5149
    ISSN 0974-2069
    DOI 10.4103/apc.APC_143_18
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  7. Article ; Online: Anomalous Origin of Right Coronary Artery from the Non-coronary Cusp Demonstrated by Echocardiography and CT Angiography.

    Jhaveri, Simone / Tower-Rader, Albree / Zahka, Kenneth

    Pediatric cardiology

    2019  Volume 40, Issue 2, Page(s) 454–455

    Abstract: Certain coronary anomalies have been associated with sudden cardiac death. Anomalous origin of the right coronary artery (RCA) from the posterior non-coronary aortic cusp is exceedingly rare. Through multimodality imaging, we present a young female with ... ...

    Abstract Certain coronary anomalies have been associated with sudden cardiac death. Anomalous origin of the right coronary artery (RCA) from the posterior non-coronary aortic cusp is exceedingly rare. Through multimodality imaging, we present a young female with an anomalous RCA arising from the non-coronary cusp. Given the unobstructed origin and benign course, no intervention was recommended.
    MeSH term(s) Adolescent ; Computed Tomography Angiography/methods ; Coronary Angiography/methods ; Coronary Vessel Anomalies/diagnostic imaging ; Echocardiography/methods ; Female ; Humans ; Imaging, Three-Dimensional/methods ; Multimodal Imaging
    Language English
    Publishing date 2019-01-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 800857-7
    ISSN 1432-1971 ; 0172-0643
    ISSN (online) 1432-1971
    ISSN 0172-0643
    DOI 10.1007/s00246-019-02055-w
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1528: Show issues Location:
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  8. Article ; Online: Reply.

    Kaushik, Shubhi / Jhaveri, Simone / Derespina, Kim R / Medar, Shivanand S / Stern, Kenan / Aydin, Scott I

    The Journal of pediatrics

    2020  Volume 228, Page(s) 315–316

    Language English
    Publishing date 2020-11-02
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2020.09.055
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  9. Article ; Online: Rare case of septum primum malposition defect in dextrocardia and situs inversus totalis without heterotaxy syndrome.

    Jhaveri, Simone / Erenberg, Francine / Yaman, Malek

    Cardiology in the young

    2018  Volume 29, Issue 3, Page(s) 419–421

    Abstract: Septum primum malposition defect is an extremely rare CHD and is often found in patients with visceral heterotaxy, particularly of the polysplenia type. We describe a unique patient with dextrocardia, situs inversus totalis, and bilateral superior vena ... ...

    Abstract Septum primum malposition defect is an extremely rare CHD and is often found in patients with visceral heterotaxy, particularly of the polysplenia type. We describe a unique patient with dextrocardia, situs inversus totalis, and bilateral superior vena caval veins without heterotaxy syndrome who was diagnosed with an interatrial defect and partial anomalous pulmonary venous drainage due to malposition of the septum primum.
    Language English
    Publishing date 2018-12-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1078466-4
    ISSN 1467-1107 ; 1047-9511
    ISSN (online) 1467-1107
    ISSN 1047-9511
    DOI 10.1017/S1047951118002263
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    Zs.A 4050: Show issues Location:
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  10. Article ; Online: Left Atrial Strain and Function in Pediatric Hypertrophic Cardiomyopathy.

    Jhaveri, Simone / Komarlu, Rukmini / Worley, Sarah / Shahbah, Doaa / Gurumoorthi, Manasa / Zahka, Kenneth

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2021  Volume 34, Issue 9, Page(s) 996–1006

    Abstract: Background: Left atrial (LA) strain and dysfunction are early markers of diastolic dysfunction, associated with poor exercise capacity in adults with hypertrophic cardiomyopathy (HCM). Literature on assessment of LA mechanics in pediatric HCM is lacking. ...

    Abstract Background: Left atrial (LA) strain and dysfunction are early markers of diastolic dysfunction, associated with poor exercise capacity in adults with hypertrophic cardiomyopathy (HCM). Literature on assessment of LA mechanics in pediatric HCM is lacking. The aim of this study was to assess LA strain and LA function in pediatric patients who have HCM with (phenotype positive [P+]) and without (genotype positive, phenotype negative [G+P-]) ventricular hypertrophy and evaluate their correlation with exercise stress test parameters.
    Methods: Seventy-eight children (3-25 years of age) with HCM (P+, n = 46; G+P-, n = 32) and 20 healthy control subjects were retrospectively studied. LA conduit function, reservoir function, and pump function were computed using phasic LA volumetric analysis. LA reservoir strain (LASr) and LA contractile strain were measured using speckle-tracking echocardiography. Exercise test findings within 12 months of echocardiography were recorded.
    Results: LA conduit function (36% vs 48%, P < .001) and LA reservoir function (137% vs 180%, P < .001) were lower in P+ than in G+P- patients. LA contractile function did not differ between the groups (31% vs 32%, P = .87). Compared with patients with G+P- HCM, those with P+HCM had lower four-chamber LASr (29% vs 41%, P < .001), two-chamber LASr (30% vs 41%, P < .001), average LASr (29% vs 42%, P < .001), and LA contractile strain (9% vs 12%, P = .016). In the cohort of patients with HCM who underwent stress testing (n = 35), LA conduit function weakly correlated with aerobic capacity (r = 0.42, P = .019).
    Conclusions: Children with P+HCM have reduced LA function, measurable by both volumetric and strain analysis. Altered LA mechanics are associated with poor exercise capacity. This study lays the foundation for the evaluation of novel LA parameters in pediatric HCM and warrants larger longitudinal studies to assess its clinical significance.
    MeSH term(s) Atrial Function, Left ; Cardiomyopathy, Hypertrophic/diagnostic imaging ; Child ; Echocardiography ; Heart Atria/diagnostic imaging ; Humans ; Retrospective Studies
    Language English
    Publishing date 2021-04-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2021.04.014
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    Zs.A 2638: Show issues Location:
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