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  1. Article ; Online: Conservation finance: What are we not doing? A review and research agenda.

    Cosma, Simona / Rimo, Giuseppe / Cosma, Stefano

    Journal of environmental management

    2023  Volume 336, Page(s) 117649

    Abstract: Conservation finance embraces a series of innovative financing mechanisms aimed at raising and managing capital to be used for the conservation of biodiversity. The climate emergency and the pursuit of sustainable development underline the criticality of ...

    Abstract Conservation finance embraces a series of innovative financing mechanisms aimed at raising and managing capital to be used for the conservation of biodiversity. The climate emergency and the pursuit of sustainable development underline the criticality of financial support for achieving this goal. Funding for the protection of biodiversity, in fact, has long been disbursed by governments in a residual form, only after they have dealt with social needs and political challenges. To date, the main challenge of conservation finance is to identify solutions that not only generate new revenue for biodiversity, but also effectively manage and allocate existing funding to provide a mix of social and community benefits as well. The paper, therefore, aims to act as a wake-up call, urging academics working in economics and finance to turn their attention to resolving the financial problems faced by conservation. Through a comparative bibliometric analysis, the study aims to outline the structure of scientific research on the topic of conservation finance, to understand the state of the art, and to identify open questions and new research trends. The results of the study show that the topic of conservation finance is currently a prerogative of scholars and journals of ecology, biology and environmental sciences. Finance scholars pay very little attention to the topic and yet there are many opportunities/needs for future research. The results are of interest to researchers in banking and finance, policy-makers and managers.
    MeSH term(s) Biodiversity ; Conservation of Natural Resources/methods ; Ecology ; Sustainable Development ; Capital Financing
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2023.117649
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  2. Article ; Online: Authors' Reply.

    Cosma, Stefano / Benedetto, Chiara

    Journal of minimally invasive gynecology

    2022  Volume 29, Issue 6, Page(s) 803–804

    Language English
    Publishing date 2022-04-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2022.03.015
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Conservation finance: What are we not doing? A review and research agenda

    Cosma, Simona / Rimo, Giuseppe / Cosma, Stefano

    Journal of Environmental Management. 2023 June, v. 336 p.117649-

    2023  

    Abstract: Conservation finance embraces a series of innovative financing mechanisms aimed at raising and managing capital to be used for the conservation of biodiversity. The climate emergency and the pursuit of sustainable development underline the criticality of ...

    Abstract Conservation finance embraces a series of innovative financing mechanisms aimed at raising and managing capital to be used for the conservation of biodiversity. The climate emergency and the pursuit of sustainable development underline the criticality of financial support for achieving this goal. Funding for the protection of biodiversity, in fact, has long been disbursed by governments in a residual form, only after they have dealt with social needs and political challenges. To date, the main challenge of conservation finance is to identify solutions that not only generate new revenue for biodiversity, but also effectively manage and allocate existing funding to provide a mix of social and community benefits as well. The paper, therefore, aims to act as a wake-up call, urging academics working in economics and finance to turn their attention to resolving the financial problems faced by conservation. Through a comparative bibliometric analysis, the study aims to outline the structure of scientific research on the topic of conservation finance, to understand the state of the art, and to identify open questions and new research trends. The results of the study show that the topic of conservation finance is currently a prerogative of scholars and journals of ecology, biology and environmental sciences. Finance scholars pay very little attention to the topic and yet there are many opportunities/needs for future research. The results are of interest to researchers in banking and finance, policy-makers and managers.
    Keywords bibliometric analysis ; biodiversity ; capital ; climate ; environmental management ; funding ; income ; politics ; sustainable development ; Conservation finance ; Biodiversity conservation ; Bibliometrics ; Literature review ; Climate change
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2023.117649
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  4. Article: Classification algorithm of patients with endometriosis: Proposal for tailored management.

    Cosma, Stefano / Benedetto, Chiara

    Advances in clinical and experimental medicine : official organ Wroclaw Medical University

    2020  Volume 29, Issue 5, Page(s) 615–622

    Abstract: Endometriosis is a pseudoneoplastic disease that has a significant personal and social impact. Unlike other neoplastic diseases, its management is burdened by uncertainty and controversy. The aim of this article is to furnish clinicians with a simple, ... ...

    Abstract Endometriosis is a pseudoneoplastic disease that has a significant personal and social impact. Unlike other neoplastic diseases, its management is burdened by uncertainty and controversy. The aim of this article is to furnish clinicians with a simple, useful and updated tool to select an appropriate diagnostic-therapeutic care pathway for affected women. Guidelines and recommendations cite advances in diagnostics, novel medications and optimized assisted reproductive techniques; however, such advancements have not simplified the management of endometriosis, since they often lack an integrated, multidisciplinary view of diagnostic, therapeutic and reproductive scenarios that inevitably overlap in the management of the disease. We selected and compared major society guidelines on the diagnosis and treatment of endometriosis. Three international and 5 national guidelines were analyzed. The overlapping recommendations were extracted and mapped, developing a simplified diagnostic-therapeutic care pathway in the form of an algorithm. We subdivided the patient population attending our tertiary referral center according to 4 decision nodes: type (deep infiltrating endometriosis or isolated endometrioma); stage (I-IV according to the revised American Society for Reproductive Medicine classification); predominant health problem (pain or infertility); and fertility potential of the couple (normal/abnormal screening fertility). We identified 9 classes, each corresponding to a suggested mode of treatment (medical, surgical or assisted reproductive technique) according to the most recent evidence published. This simplified scheme is designed to standardize treatment and is intended for use as a tool in diagnostic and therapeutic planning with a view to reduce inappropriate treatment.
    MeSH term(s) Algorithms ; Endometriosis/classification ; Endometriosis/pathology ; Endometriosis/therapy ; Female ; Guidelines as Topic ; Humans ; Infertility, Female ; Laparoscopy ; Precision Medicine/methods ; Reproductive Techniques, Assisted
    Language English
    Publishing date 2020-05-21
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 2270257-X
    ISSN 1899-5276 ; 1230-025X
    ISSN 1899-5276 ; 1230-025X
    DOI 10.17219/acem/118849
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    Zs.A 6489: Show issues Location:
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  5. Article: Update on Prognostic and Predictive Markers in Mucinous Ovarian Cancer.

    Borella, Fulvio / Mitidieri, Marco / Cosma, Stefano / Benedetto, Chiara / Bertero, Luca / Fucina, Stefano / Ray-Coquard, Isabelle / Carapezzi, Annalisa / Ferraioli, Domenico

    Cancers

    2023  Volume 15, Issue 4

    Abstract: This review includes state-of-the-art prognostic and predictive factors of mucinous ovarian cancer (MOC), a rare tumor. Clinical, pathological, and molecular features and treatment options according to prognosis are comprehensively discussed. Different ... ...

    Abstract This review includes state-of-the-art prognostic and predictive factors of mucinous ovarian cancer (MOC), a rare tumor. Clinical, pathological, and molecular features and treatment options according to prognosis are comprehensively discussed. Different clinical implications of MOC are described according to the The International Federation of Gynecology and Obstetrics (FIGO) stage: early MOC (stage I-II) and advanced MOC (stage III-IV). Early MOC is characterized by a good prognosis. Surgery is the mainstay of treatment. Fertility-sparing surgery could be performed in patients who wish to become pregnant and that present low recurrence risk of disease. Adjuvant chemotherapy is not recommended, except in patients with high-risk clinical and pathological features. Regarding the histological features, an infiltrative growth pattern is the major prognostic factor of MOC. Furthermore, novel molecular biomarkers are emerging for tailored management of early-stage MOC. In contrast, advanced MOC is characterized by poor survival. Radical surgery is the cornerstone of treatment and adjuvant chemotherapy is recommended, although the efficacy is limited by the intrinsic chemoresistance of these tumors. Several molecular hallmarks of advanced MOC have been described in recent years (e.g., HER2 amplification, distinct methylation profiles, peculiar immunological microenvironment), but target therapy for these rare tumors is not available yet.
    Language English
    Publishing date 2023-02-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15041172
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  6. Article ; Online: Vaginal delivery in COVID-19 pregnant women: anorectum as a potential alternative route of SARS-CoV-2 transmission.

    Carosso, Andrea Roberto / Cosma, Stefano / Benedetto, Chiara

    American journal of obstetrics and gynecology

    2020  Volume 223, Issue 4, Page(s) 612

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Delivery, Obstetric ; Female ; Genitalia ; Humans ; Pandemics ; Pneumonia, Viral ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome
    Keywords covid19
    Language English
    Publishing date 2020-06-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2020.06.012
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    Um I Zs.152: Show issues Location:
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  7. Article: Reproductive and Obstetric Outcomes Following a Natural Cycle vs. Artificial Endometrial Preparation for Frozen-Thawed Embryo Transfer: A Retrospective Cohort Study.

    Carosso, Andrea Roberto / Brunod, Nicole / Filippini, Claudia / Revelli, Alberto / Evangelisti, Bernadette / Cosma, Stefano / Borella, Fulvio / Canosa, Stefano / Benedetto, Chiara / Gennarelli, Gianluca

    Journal of clinical medicine

    2023  Volume 12, Issue 12

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-06-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12124032
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  8. Article: Hormone Receptors and Epithelial Ovarian Cancer: Recent Advances in Biology and Treatment Options.

    Borella, Fulvio / Fucina, Stefano / Mangherini, Luca / Cosma, Stefano / Carosso, Andrea Roberto / Cusato, Jessica / Cassoni, Paola / Bertero, Luca / Katsaros, Dionyssios / Benedetto, Chiara

    Biomedicines

    2023  Volume 11, Issue 8

    Abstract: Epithelial ovarian cancer (EOC) is a significant cause of cancer-related mortality in women. Despite advances in diagnosis and treatment, EOC remains a challenging disease to manage, and the 5-year survival rate is still poor. The role of hormone ... ...

    Abstract Epithelial ovarian cancer (EOC) is a significant cause of cancer-related mortality in women. Despite advances in diagnosis and treatment, EOC remains a challenging disease to manage, and the 5-year survival rate is still poor. The role of hormone receptors (HRs) in EOC carcinogenesis and prognosis has been actively explored; however, the role of hormone therapy (HT) in the treatment of these tumors is not well established. Most available data on HT mainly come from retrospective series and small early clinical trials. Several of these studies suggest that HT may have a role in adjuvant, maintenance therapy, or in the case of recurrent disease, especially for some subtypes of EOC (e.g., low-grade serous EOC). Furthermore, HT has recently been combined with targeted therapies, but most studies evaluating these combinations are still ongoing. The main aim of this review is to provide an overview of the progress made in the last decade to characterize the biological and prognostic role of HRs for EOC and the developments in their therapeutic targeting through HT.
    Language English
    Publishing date 2023-08-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11082157
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  9. Article ; Online: Placenta-mediated pregnancy complications in women with a history of late fetal loss and placental infarction without thrombophilia: risk of recurrence and efficacy of pharmacological prophylactic interventions. A 10-year retrospective study.

    Borella, Fulvio / Marozio, Luca / Bertschy, Gianluca / Botta, Giovanni / Bertero, Luca / Cassoni, Paola / Maina, Aldo / Cosma, Stefano / Benedetto, Chiara

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2023  Volume 36, Issue 1, Page(s) 2183748

    Abstract: Purpose: To evaluate the risk of recurrence of severe placenta-mediated pregnancy complications and compare the efficacy of two different anti-thrombotic regimens in women with a history of late fetal loss without thrombophilia.: Patients and methods!# ...

    Abstract Purpose: To evaluate the risk of recurrence of severe placenta-mediated pregnancy complications and compare the efficacy of two different anti-thrombotic regimens in women with a history of late fetal loss without thrombophilia.
    Patients and methods: We performed a 10-year retrospective observational study (2008-2018) analyzing a cohort of 128 women who suffered from pregnancy fetal loss (>20 weeks of gestational age) with histological evidence of placental infarction. All the women tested negative for congenital and/or acquired thrombophilia. In their subsequent pregnancies, 55 received prophylaxis with acetylsalicylic acid (ASA) only and 73 received ASA plus low molecular weight heparin (LMWH).
    Results: Overall, one-third of all pregnancies (31%) had adverse outcomes related to placental dysfunction: pre-term births (25% <37 weeks, 5.6% <34 weeks), newborns with birth weight <2500 g (17%), and newborns small for gestational age (5%). The prevalence of placental abruption, early and/or severe preeclampsia, and fetal loss >20 weeks were 6%, 5%, and 4% respectively. We found a risk reduction for combination therapy (ASA plus LMWH) compared with ASA alone for delivery <34 weeks (RR 0.11, 95% CI: 0.01-0.95
    Conclusion: In our study population, the risk of recurrence of placenta-mediated pregnancy complications is substantial, even in the absence of maternal thrombophilic conditions. A reduction of the risk of delivery <34 weeks was detected in the ASA plus LMWH group.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Placenta ; Retrospective Studies ; Pre-Eclampsia ; Heparin, Low-Molecular-Weight ; Placenta Diseases ; Thrombophilia ; Abortion, Spontaneous ; Aspirin ; Infarction
    Chemical Substances Heparin, Low-Molecular-Weight ; Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2023-02-09
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2023.2183748
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    Zs.A 3510: Show issues Location:
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  10. Article: Case Report:Pregnancy and birth in a mild phenotype of Alström syndrome.

    Marozio, Luca / Dassie, Francesca / Bertschy, Gianluca / Canuto, Emilie M / Milan, Gabriella / Cosma, Stefano / Maffei, Pietro / Benedetto, Chiara

    Frontiers in genetics

    2022  Volume 13, Page(s) 995947

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-10-03
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.995947
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