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  1. Article ; Online: Linear dichroism and linearly polarised luminescence spectra of oriented samples collected on a new integrated instrument.

    Rodger, Alison

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 28, Page(s) 3850–3853

    Abstract: Linearly polarised luminescence (LPL) has a wide range of potential applications giving optical and geometric parameters for oriented lumiphores. In this work we present the first wavelength scanned LPL spectra. Analytes are either oriented on stretched ... ...

    Abstract Linearly polarised luminescence (LPL) has a wide range of potential applications giving optical and geometric parameters for oriented lumiphores. In this work we present the first wavelength scanned LPL spectra. Analytes are either oriented on stretched polyethylene films or in flow. Applications of the wavelength-dependence of
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d4cc00038b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Traitement de la tuberculose basé sur le DOTS et lutte antituberculeuse dans un contexte de conflits et d' épidémie de VIH dans le district de Churachandpur (Inde) / Alison J. Rodger . [et al.]

    Rodger, Alison J / Toole, Mike / Lalnuntluangi, Baby / Muana, V / Deutschmann, Peter

    2002  

    Keywords Tuberculosis ; Pulmonary ; HIV seropositivity ; Substance abuse ; Intravenous ; Treatment outcome ; Refugees ; Ethnic groups ; War ; Risk factors ; Guideline adherence ; India ; Communicable Diseases and their Control ; diagnosis drug therapy
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Journal ; Article ; Online: Traitement de la tuberculose basé sur le DOTS et lutte antituberculeuse dans un contexte de conflits et d' épidémie de VIH dans le district de Churachandpur (Inde) / Alison J. Rodger . [et al.]

    Rodger, Alison J / Toole, Mike / Lalnuntluangi, Baby / Muana, V / Deutschmann, Peter

    2002  

    Keywords Tuberculosis ; Pulmonary ; HIV Seropositivity ; Substance Abuse ; Intravenous ; Treatment Outcome ; Refugees ; Ethnic Groups ; Armed Conflicts ; Risk Factors ; Guideline Adherence ; India ; Communicable Diseases and their Control ; diagnosis drug therapy
    Language French
    Document type Journal ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: DOTS-based tuberculosis treatment and control during civil conflict and an HIV epidemic, Churachandpur District, India / Alison J. Rodger . [et al.] ; Traitement de la tuberculose basé sur le DOTS et lutte antituberculeuse dans un contexte de conflits et d' épidémie de VIH dans le district de Churachandpur (Inde)

    Rodger, Alison J / Toole, Mike / Lalnuntluangi, Baby / Muana, V / Deutschmann, Peter

    résumé ; Tratamiento y control de la tuberculosis mediante DOTS en un contexto de disturbios y epidemia de VIH en el distrito de Churachandpur (India) : resumen

    2002  

    Abstract: Summaries in English, French and ... ...

    Abstract Summaries in English, French and Spanish
    Keywords Tuberculosis ; Pulmonary ; HIV seropositivity ; Substance abuse ; Intravenous ; Treatment outcome ; Refugees ; Ethnic groups ; War ; Risk factors ; Guideline adherence ; India ; Communicable Diseases and their Control ; diagnosis drug therapy
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Article ; Online: DOTS-based tuberculosis treatment and control during civil conflict and an HIV epidemic, Churachandpur District, India / Alison J. Rodger . [et al.] ; Traitement de la tuberculose basé sur le DOTS et lutte antituberculeuse dans un contexte de conflits et d' épidémie de VIH dans le district de Churachandpur (Inde)

    Rodger, Alison J / Toole, Mike / Lalnuntluangi, Baby / Muana, V / Deutschmann, Peter

    résumé ; Tratamiento y control de la tuberculosis mediante DOTS en un contexto de disturbios y epidemia de VIH en el distrito de Churachandpur (India) : resumen

    2002  

    Abstract: Summaries in English, French and ... ...

    Abstract Summaries in English, French and Spanish
    Keywords Tuberculosis ; Pulmonary ; HIV Seropositivity ; Substance Abuse ; Intravenous ; Treatment Outcome ; Refugees ; Ethnic Groups ; Armed Conflicts ; Risk Factors ; Guideline Adherence ; India ; Communicable Diseases and their Control ; diagnosis drug therapy
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Advantages of a synchrotron light source for fluorescence-detected linear dichroism.

    Jones, Nykola C / Rodger, Alison / Hoffmann, Søren V

    Chirality

    2024  Volume 36, Issue 4, Page(s) e23667

    Abstract: Fluorescence-detected linear dichroism (FD-LD) enables one to collect linear dichroism spectra for oriented fluorophores in the presence of other absorbing species and light scattering. The experiment proceeds by scanning the excitation wavelength and ... ...

    Abstract Fluorescence-detected linear dichroism (FD-LD) enables one to collect linear dichroism spectra for oriented fluorophores in the presence of other absorbing species and light scattering. The experiment proceeds by scanning the excitation wavelength and using a filter to collect only emitted photons from the fluorophore. Thus, it has the potential to give data with enhanced selectivity and quality. By using a synchrotron radiation light source and fluorescence-detection, we show data for a range of fluorophores in different orienting environments. Film and flow-oriented FD-LD spectra were collected down to 170 nm. Even for flow-oriented liposomes, we have data collected down to 210 nm. For strongly scattering samples, for example, liposomes, FD-LD has the clear advantage that scattering is absent for the longer wavelength fluorescence photons. The collimated and smaller beam size of the synchrotron radiation also gives rise to sharper and more well-defined features in the spectra.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1011639-4
    ISSN 1520-636X ; 0899-0042
    ISSN (online) 1520-636X
    ISSN 0899-0042
    DOI 10.1002/chir.23667
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2594: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book: HIV AIDS

    Rodger, Alison J. / Mahungu, Tabitha W. / Johnson, Margaret A.

    (An atlas of investigation and management)

    2011  

    Author's details ed. by Alison J. Rodger ; Tabitha W. Mahungu ; Margaret A. Johnson
    Series title An atlas of investigation and management
    Language English
    Size X, 166 S. : zahlr. Ill., graph. Darst., Kt.
    Publisher Clinical Publ
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT016923176
    ISBN 978-1-904392-90-3 ; 9781846926297 ; 1-904392-90-3 ; 1846926297
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 5196 order for loan Magazin

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  8. Article ; Online: Minimising sample volume and run times for circular dichroism spectroscopy.

    Rodger, Alison / Chin, Timothy

    Analytical methods : advancing methods and applications

    2022  Volume 14, Issue 23, Page(s) 2337–2340

    Abstract: Circular dichroism (CD) spectroscopy is widely used to characterise chiral structures in solution, including to determine protein secondary structure content. However, protein CD experiments typically require 10-20 μg of protein. An additional challenge ... ...

    Abstract Circular dichroism (CD) spectroscopy is widely used to characterise chiral structures in solution, including to determine protein secondary structure content. However, protein CD experiments typically require 10-20 μg of protein. An additional challenge is that some proteins change their structure when their concentration is changed (they unfold or aggregate) so, particularly for protein biopharmaceuticals, it is attractive to have a range of different path lengths to hand. This paper reports the validation of demountable DMV Bio-cells of path lengths 0.5 mm, 0.2 mm and 0.125 mm, which have approximately 1 mm diameter windows, for CD spectroscopy. When complemented with a 10 cm focal length focusing lens positioned 9.5 cm in front of the sample, the signal : noise ratio of the final spectrum is equivalent to data collected on a standard cell wide enough to allow the full light beam to pass through. The DMV Bio-cells require 2-3% of the sample needed for a standard full-width cuvette and can be assembled without bubbles with the nominal path length. In addition, they are easy to clean and less likely to be chipped or broken than standard cuvettes which, together with the sample saved, compensates for their much higher price. For smaller path lengths the Jasco MSD-462 microsampling disk enabled fairly reproducible assembly at 4-7 μm depending on the sample viscosity and similarly high quality data.
    MeSH term(s) Circular Dichroism ; Protein Structure, Secondary ; Proteins/chemistry
    Chemical Substances Proteins
    Language English
    Publishing date 2022-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d2ay00298a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Couette flow fluorescence detected linear dichroism for analytes in lipid bilayers.

    Rodger, Alison / Kitamura, Junya / Sato, Akihiro / Shao, Ping

    Chirality

    2023  Volume 35, Issue 8, Page(s) 498–504

    Abstract: Membranes are important sites of intermolecular interactions in biological systems. However, they present significant analytical challenges as they contain multiple analytes and are dynamic in nature. In this work, we show how a Jasco J-1500 circular ... ...

    Abstract Membranes are important sites of intermolecular interactions in biological systems. However, they present significant analytical challenges as they contain multiple analytes and are dynamic in nature. In this work, we show how a Jasco J-1500 circular dichroism spectropolarimeter can be used with a microvolume Couette flow cell and appropriate cut-off filters to measure excitation fluorescence detected linear dichroism (FDLD) of fluorophores embedded in liposomal membranes. The result is a spectrum that selectively probes the fluorophore(s) and eliminates the scattering that is apparent in the corresponding flow linear dichroism (LD) spectrum. The FDLD spectrum is opposite in sign from the LD spectrum with relative magnitudes modified by the quantum yields of the transitions. FDLD thus enables analyte orientations to be identified in a membrane. Data for a membrane peptide, gramicidin, and two aromatic analytes, anthracene and pyrene, are presented. Issues with the "leakage" of photons by the long pass filters used is also discussed.
    MeSH term(s) Lipid Bilayers/chemistry ; Stereoisomerism ; Circular Dichroism ; Gramicidin/chemistry ; Peptides/chemistry
    Chemical Substances Lipid Bilayers ; Gramicidin (1405-97-6) ; Peptides
    Language English
    Publishing date 2023-03-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1011639-4
    ISSN 1520-636X ; 0899-0042
    ISSN (online) 1520-636X
    ISSN 0899-0042
    DOI 10.1002/chir.23554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2594: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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  10. Article: Minimising sample volume and run times for circular dichroism spectroscopy

    Rodger, Alison / Chin, Timothy

    Analytical methods. 2022 June 16, v. 14, no. 23

    2022  

    Abstract: Circular dichroism (CD) spectroscopy is widely used to characterise chiral structures in solution, including to determine protein secondary structure content. However, protein CD experiments typically require 10–20 μg of protein. An additional challenge ... ...

    Abstract Circular dichroism (CD) spectroscopy is widely used to characterise chiral structures in solution, including to determine protein secondary structure content. However, protein CD experiments typically require 10–20 μg of protein. An additional challenge is that some proteins change their structure when their concentration is changed (they unfold or aggregate) so, particularly for protein biopharmaceuticals, it is attractive to have a range of different path lengths to hand. This paper reports the validation of demountable DMV Bio-cells of path lengths 0.5 mm, 0.2 mm and 0.125 mm, which have approximately 1 mm diameter windows, for CD spectroscopy. When complemented with a 10 cm focal length focusing lens positioned 9.5 cm in front of the sample, the signal : noise ratio of the final spectrum is equivalent to data collected on a standard cell wide enough to allow the full light beam to pass through. The DMV Bio-cells require 2–3% of the sample needed for a standard full-width cuvette and can be assembled without bubbles with the nominal path length. In addition, they are easy to clean and less likely to be chipped or broken than standard cuvettes which, together with the sample saved, compensates for their much higher price. For smaller path lengths the Jasco MSD-462 microsampling disk enabled fairly reproducible assembly at 4–7 μm depending on the sample viscosity and similarly high quality data.
    Keywords biopharmaceuticals ; circular dichroism spectroscopy ; prices ; protein secondary structure ; viscosity
    Language English
    Dates of publication 2022-0616
    Size p. 2337-2340.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d2ay00298a
    Database NAL-Catalogue (AGRICOLA)

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