LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 2751

Search options

  1. Article ; Online: NLRP3 inflammasome activation triggers severe inflammatory liver injury in N, N-dimethylformamide-exposed mice.

    Zhang, Xiu-Ning / Zhang, Yan-Jing / Wang, Lin / Hong, Shu-Jun / Zhang, Cui-Li / Zhao, Xiu-Lan / Zeng, Tao

    The Science of the total environment

    2024  Volume 929, Page(s) 172653

    Abstract: N,N-dimethylformamide (DMF) is a widely utilized chemical solvent with various industrial applications. Previous studies have indicated that the liver is the most susceptible target to DMF exposure, whereas the underlying mechanisms remain to be ... ...

    Abstract N,N-dimethylformamide (DMF) is a widely utilized chemical solvent with various industrial applications. Previous studies have indicated that the liver is the most susceptible target to DMF exposure, whereas the underlying mechanisms remain to be elucidated. This study aimed to investigate the role of NLRP3 inflammasome in DMF-induced liver injury in mice by using two NLRP3 inflammasome inhibitors, Nlrp3
    Language English
    Publishing date 2024-04-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172653
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Transcriptome and Metabolome Analyses of

    Yuan, Fang / Yin, Xiu / Zhao, Kaihui / Lan, Xiaozhong

    Frontiers in genetics

    2022  Volume 13, Page(s) 884224

    Abstract: ... ...

    Abstract Codonopsis
    Language English
    Publishing date 2022-07-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.884224
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Effect of the small incision lenticule extraction (SMILE) on anxiety in treating high myopia: A single campus survey study.

    Li, Qing / Lan, Xiu-Lin / Chen, Jindong / Zeng, Deming

    Asian journal of surgery

    2023  Volume 47, Issue 1, Page(s) 519–520

    MeSH term(s) Humans ; Myopia/surgery ; Retrospective Studies ; Anxiety/etiology ; Anxiety/prevention & control ; Surgical Wound
    Language English
    Publishing date 2023-11-02
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.10.101
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: An Adaptive Region-Based Transformer for Nonrigid Medical Image Registration With a Self-Constructing Latent Graph.

    Lan, Sheng / Li, Xiu / Guo, Zhenhua

    IEEE transactions on neural networks and learning systems

    2023  Volume PP

    Abstract: Nonrigid registration of medical images is formulated usually as an optimization problem with the aim of seeking out the deformation field between a referential-moving image pair. During the past several years, advances have been achieved in the ... ...

    Abstract Nonrigid registration of medical images is formulated usually as an optimization problem with the aim of seeking out the deformation field between a referential-moving image pair. During the past several years, advances have been achieved in the convolutional neural network (CNN)-based registration of images, whose performance was superior to most conventional methods. More lately, the long-range spatial correlations in images have been learned by incorporating an attention-based model into the transformer network. However, medical images often contain plural regions with structures that vary in size. The majority of the CNN-and transformer-based approaches adopt embedding of patches that are identical in size, disallowing representation of the inter-regional structural disparities within an image. Besides, it probably leads to the structural and semantical inconsistencies of objects as well. To address this issue, we put forward an innovative module called region-based structural relevance embedding (RSRE), which allows adaptive embedding of an image into unequally-sized structural regions based on the similarity of self-constructing latent graph instead of utilizing patches that are identical in size. Additionally, a transformer is integrated with the proposed module to serve as an adaptive region-based transformer (ART) for registering medical images nonrigidly. As demonstrated by the experimental outcomes, our ART is superior to the advanced nonrigid registration approaches in performance, whose Dice score is 0.734 on the LPBA40 dataset with 0.318% foldings for deformation field, and is 0.873 on the ADNI dataset with 0.331% foldings.
    Language English
    Publishing date 2023-07-24
    Publishing country United States
    Document type Journal Article
    ISSN 2162-2388
    ISSN (online) 2162-2388
    DOI 10.1109/TNNLS.2023.3294290
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Investigation of volatile compounds during fermentation of

    Wang, Yixuan / Li, Wenhao / Wang, Xiaojun / Hu, Qi / Kong, Junkai / Wang, Xiu / Lan, Zhenghui / Wang, Chenxi / Zhang, Yan

    Food chemistry: X

    2024  Volume 21, Page(s) 101171

    Abstract: The influence on and biotransformation of volatile compounds (VOCs) during fermentation ... ...

    Abstract The influence on and biotransformation of volatile compounds (VOCs) during fermentation of
    Language English
    Publishing date 2024-02-06
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1575
    ISSN (online) 2590-1575
    DOI 10.1016/j.fochx.2024.101171
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Minocycline Activates the Nucleus of the Solitary Tract-Associated Network to Alleviate Lipopolysaccharide-Induced Neuroinflammation.

    Xiu, Jian-Bo / Li, Lan-Lan / Xu, Qi

    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih

    2021  Volume 37, Issue 1, Page(s) 1–14

    Abstract: Objective To examine the neuroanatomical substrates underlying the effects of minocycline in alleviating lipopolysaccharide (LPS)-induced neuroinflammation. Methods Forty C57BL/6 male mice were randomly and equally divided into eight groups. Over three ... ...

    Abstract Objective To examine the neuroanatomical substrates underlying the effects of minocycline in alleviating lipopolysaccharide (LPS)-induced neuroinflammation. Methods Forty C57BL/6 male mice were randomly and equally divided into eight groups. Over three conse-cutive days, saline was administered to four groups of mice and minocycline to the other four groups. Immediately after the administration of saline or minocycline on the third day, two groups of mice were additionally injected with saline and the other two groups were injected with LPS. Six or 24 hours after the last injection, mice were sacrificed and the brains were removed. Immunohistochemical staining across the whole brain was performed to detect microglia activation via Iba1 and neuronal activation via c-Fos. Morphology of microglia and the number of c-Fo-positive neurons were analyzed by Image-Pro Premier 3D. One-way ANOVA and Fisher's least-significant differences were employed for statistical analyses. Results Minocycline alleviated LPS-induced neuroinflammation as evidenced by reduced activation of microglia in multiple brain regions, including the shell part of the nucleus accumbens (Acbs), paraventricular nucleus (PVN) of the hypothalamus, central nucleus of the amygdala (CeA), locus coeruleus (LC), and nucleus tractus solitarius (NTS). Minocycline significantly increased the number of c-Fo-positive neurons in NTS and area postrema (AP) after LPS treatment. Furthermore, in NTS-associated brain areas, including LC, lateral parabrachial nucleus (LPB), periaqueductal gray (PAG), dorsal raphe nucleus (DR), amygdala, PVN, and bed nucleus of the stria terminali (BNST), minocycline also significantly increased the number of c-Fo-positive neurons after LPS administration. Conclusion Minocycline alleviates LPS-induced neuroinflammation in multiple brain regions, possibly due to increased activation of neurons in the NTS-associated network.
    MeSH term(s) Animals ; Female ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred C57BL ; Minocycline/pharmacology ; Neuroinflammatory Diseases ; Solitary Nucleus
    Chemical Substances Lipopolysaccharides ; Minocycline (FYY3R43WGO)
    Language English
    Publishing date 2021-07-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 1083365-1
    ISSN 1001-9294
    ISSN 1001-9294
    DOI 10.24920/003954
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 3196: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Cyanidin-3-

    Wang, Jing-Ya / Zhang, Fa-Li / Li, Xiu-Xiu / Zhu, Ke-Xin / Zuo, Ning / Wang, Jun-Jie / Shen, Wei / Li, Lan

    Journal of agricultural and food chemistry

    2023  Volume 71, Issue 44, Page(s) 16715–16726

    Abstract: Zearalenone (ZEN) is well known as a kind of endocrine disruptor whose exposure is capable of causing reproductive toxicity in animals. Cyanidin-3- ...

    Abstract Zearalenone (ZEN) is well known as a kind of endocrine disruptor whose exposure is capable of causing reproductive toxicity in animals. Cyanidin-3-
    MeSH term(s) Female ; Animals ; Mice ; Ovary ; Zearalenone/toxicity ; Tumor Suppressor Protein p53 ; Anthocyanins/pharmacology ; Glucosides/pharmacology
    Chemical Substances Zearalenone (5W827M159J) ; cyanidin (7732ZHU564) ; Tumor Suppressor Protein p53 ; Anthocyanins ; Glucosides
    Language English
    Publishing date 2023-10-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241619-0
    ISSN 1520-5118 ; 0021-8561
    ISSN (online) 1520-5118
    ISSN 0021-8561
    DOI 10.1021/acs.jafc.3c03315
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1172: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Perceptions about respiratory syncytial virus (RSV) and attitudes toward the RSV vaccine among the general public in China: A cross-sectional survey.

    Wang, Qiang / Xiu, Shixin / Yang, Liuqing / Li, Lan / Yang, Min / Wang, Xuwen / Shen, Yuan / Wang, Weibing / Lin, Leesa

    Human vaccines & immunotherapeutics

    2024  Volume 20, Issue 1, Page(s) 2310916

    Abstract: Our study aims to assess the public's perceptions of respiratory syncytial virus (RSV) and attitudes toward the RSV vaccine and to identify associated factors in China. A nationwide cross-sectional survey conducted using an online platform between August ...

    Abstract Our study aims to assess the public's perceptions of respiratory syncytial virus (RSV) and attitudes toward the RSV vaccine and to identify associated factors in China. A nationwide cross-sectional survey conducted using an online platform between August 16 and September 14, 2023. Questions related to socio-demographics, awareness, knowledge, perceptions of susceptibility and severity of RSV, and attitudes toward the RSV vaccine were included in the questionnaire. We used the chi-square test and logistic regression model to explore the associated factors. Overall, 2133 individuals were included in this study. Nearly a quarter of participants (24.3%) indicated that they had never heard of RSV. The proportion of individuals aged over 50 years reporting never having heard of RSV (36.5%) and having a low knowledge level of RSV (55.3%) was significantly higher that of other younger age groups. More than half of individuals (55.7%) exhibited low level of perceptions of susceptibility concerning RSV infection. A total of 68.4% of the participants expressed willingness to receive the RSV vaccine. Younger age was positively associated with a higher willingness to be vaccinated. The most frequent reason for declining the vaccine was "Concern about vaccine's safety or side effects." About 60% of individuals considered a price of RSV vaccine below 200 CNY (28 USD) as acceptable. The awareness and perceived susceptibility to RSV infection were limited to the Chinese public. It is necessary to take measures to address the low awareness and knowledge of RSV and acceptability of the RSV vaccine among older adults.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Respiratory Syncytial Virus Infections ; Cross-Sectional Studies ; Respiratory Syncytial Virus Vaccines ; Vaccination ; Respiratory Syncytial Virus, Human ; China ; Antibodies, Viral
    Chemical Substances Respiratory Syncytial Virus Vaccines ; Antibodies, Viral
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2024.2310916
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6967: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Hydrothermal synthesis, structure, and catalytic properties of a (4,6)-connected framework constructed from Keggin-type polyoxometalate units and tetranuclear copper complexes

    Jia-Yu Sun / Zi-Lan Wang / Zhong Zhang / Guo-Cheng Liu / Xiu-Li Wang

    Polyoxometalates, Vol 3, Iss 1, p

    2024  Volume 9140039

    Abstract: Under hydrothermal conditions, a Keggin-type polyoxometalate-based metal–organic complex, H4{[Cu4(EDDP)2(H2O)5]1.5(SiW12O40)}∙7.5H2O (CuW-EDDP, H4EDDP = ethylene-diamine-N,N'-dipropionic acid), was synthesized by reacting Na10[A-α-SiW9O34]·18H2O and ... ...

    Abstract Under hydrothermal conditions, a Keggin-type polyoxometalate-based metal–organic complex, H4{[Cu4(EDDP)2(H2O)5]1.5(SiW12O40)}∙7.5H2O (CuW-EDDP, H4EDDP = ethylene-diamine-N,N'-dipropionic acid), was synthesized by reacting Na10[A-α-SiW9O34]·18H2O and CuCl2·2H2O in the presence of H4EDDP ligands and characterized by powder and single-crystal X-ray diffraction, infrared spectroscopy, elemental analysis, and thermogravimetry. Interestingly, CuW-EDDP exhibited a three-dimensional structure with (4,6)-connected constructed from [SiW12O40]4− units and tetranuclear Cu complexes [Cu4(EDDP)2(H2O)5]. As an effective heterogeneous catalyst, CuW-EDDP exhibited excellent performance, good reusability, and structural stability in the selective oxidation of methyl phenyl sulfide with high conversion (100%) and selectivity (98%) within 30 min. Furthermore, the catalytic activity of CuW-EDDP in the oxidation of other sulfide derivatives was investigated.
    Keywords polyoxometalates ; keggin-type ; metal–organic complex ; catalytic oxidation ; sulfides ; Inorganic chemistry ; QD146-197
    Subject code 540
    Language English
    Publishing date 2024-03-01T00:00:00Z
    Publisher Tsinghua University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Could IL-25 be a potential therapeutic target for intestinal inflammatory diseases?

    Chen, Jie / Wang, Yingshu / Shen, Lan / Xiu, Yanfeng / Wang, Bing

    Cytokine & growth factor reviews

    2022  Volume 69, Page(s) 43–50

    Abstract: As a member of the IL-17 cytokine family, IL-25 (also called IL-17E) induces and sustains type 2 immunity. IL-25, which is mainly produced by intestinal epithelial cells, has been gradually investigated in recent years for its function in intestinal ... ...

    Abstract As a member of the IL-17 cytokine family, IL-25 (also called IL-17E) induces and sustains type 2 immunity. IL-25, which is mainly produced by intestinal epithelial cells, has been gradually investigated in recent years for its function in intestinal inflammation but is not yet fully understood. This review summarizes the expression and function of IL-25 in the intestine, especially the progression of its regulatory role on type 2 immunity-related cells. Finally, we discuss the dual role of IL-25 based on inflammatory bowel disease to inform research on targeting IL-25 for the treatment of intestinal inflammatory diseases.
    MeSH term(s) Humans ; Interleukin-17 ; Intestines ; Cytokines ; Inflammatory Bowel Diseases/drug therapy ; Epithelial Cells/metabolism ; Intestinal Mucosa
    Chemical Substances Interleukin-17 ; Cytokines
    Language English
    Publishing date 2022-07-06
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1330534-7
    ISSN 1879-0305 ; 1359-6101
    ISSN (online) 1879-0305
    ISSN 1359-6101
    DOI 10.1016/j.cytogfr.2022.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2653: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top