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  1. Article ; Online: Metacontrol of human creativity: The neurocognitive mechanisms of convergent and divergent thinking.

    Zhang, Weitao / Sjoerds, Zsuzsika / Hommel, Bernhard

    NeuroImage

    2020  Volume 210, Page(s) 116572

    Abstract: Creativity is a complex construct that would benefit from a more comprehensive mechanistic approach. Two processes have been defined to be central to creative cognition: divergent and convergent thinking. These two processes are most often studied using ... ...

    Abstract Creativity is a complex construct that would benefit from a more comprehensive mechanistic approach. Two processes have been defined to be central to creative cognition: divergent and convergent thinking. These two processes are most often studied using the Alternate Uses Test (heavily relying on divergent thinking), and the Remote Associates Test (heavily relying on convergent thinking, at least with analytical solutions). Although creative acts should be regarded compound processes, most behavioral and neuroimaging studies ignore the composition of basic operations relevant for the task they investigate. In order to provide leverage for a more mechanistic, and eventually even comprehensive computational, approach to creative cognition, we compare findings from divergent and convergent thinking studies and review the similarities and differences between the two underlying types of processes, from a neurocognitive perspective with a strong focus on cortical structures. In this narrative review, we discuss a broad scope of neural correlates of divergent and convergent thinking. We provide a first step towards theoretical integration, by suggesting that creative cognition in divergent- and convergent-thinking heavy tasks is modulated by metacontrol states, where divergent thinking and insight solutions in convergent-thinking tasks seem to benefit from metacontrol biases towards flexibility, whereas convergent, analytical thinking seems to benefit from metacontrol biases towards persistence. These particular biases seem to be reflected by specific cortical brain-activation patterns, involving left frontal and right temporal/parietal networks. Our tentative framework could serve as a first proxy to guide neuroscientific creativity research into assessing more mechanistic details of human creative cognition.
    MeSH term(s) Cerebral Cortex/physiology ; Creativity ; Humans ; Metacognition/physiology ; Nerve Net/physiology ; Thinking/physiology
    Language English
    Publishing date 2020-01-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1147767-2
    ISSN 1095-9572 ; 1053-8119
    ISSN (online) 1095-9572
    ISSN 1053-8119
    DOI 10.1016/j.neuroimage.2020.116572
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3664: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 7: Show issues

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  2. Article ; Online: The exploration-exploitation trade-off in a foraging task is affected by mood-related arousal and valence.

    van Dooren, Roel / de Kleijn, Roy / Hommel, Bernhard / Sjoerds, Zsuzsika

    Cognitive, affective & behavioral neuroscience

    2021  Volume 21, Issue 3, Page(s) 549–560

    Abstract: The exploration-exploitation trade-off shows conceptual, functional, and neural analogies with the persistence-flexibility trade-off. We investigated whether mood, which is known to modulate the persistence-flexibility balance, would similarly affect the ...

    Abstract The exploration-exploitation trade-off shows conceptual, functional, and neural analogies with the persistence-flexibility trade-off. We investigated whether mood, which is known to modulate the persistence-flexibility balance, would similarly affect the exploration-exploitation trade-off in a foraging task. More specifically, we tested whether interindividual differences in foraging behavior can be predicted by mood-related arousal and valence. In 119 participants, we assessed mood-related interindividual differences in exploration-exploitation using a foraging task that included minimal task constraints to reduce paradigm-induced biases of individual control tendencies. We adopted the marginal value theorem as a model-based analysis approach, which approximates optimal foraging behavior by tackling the patch-leaving problem. To assess influences of mood on foraging, participants underwent either a positive or negative mood induction. Throughout the experiment, we assessed arousal and valence levels as predictors for explorative/exploitative behavior. Our mood manipulation affected participants' arousal and valence ratings as expected. Moreover, mood-related arousal was found to predict exploration while valence predicted exploitation, which only partly matched our expectations and thereby the proposed conceptual overlap with flexibility and persistence, respectively. The current study provides a first insight into how processes related to arousal and valence differentially modulate foraging behavior. Our results imply that the relationship between exploration-exploitation and flexibility-persistence is more complicated than the semantic overlap between these terms might suggest, thereby calling for further research on the functional, neural, and neurochemical underpinnings of both trade-offs.
    MeSH term(s) Affect ; Arousal ; Attention ; Exploratory Behavior ; Humans
    Language English
    Publishing date 2021-06-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2029088-3
    ISSN 1531-135X ; 1530-7026
    ISSN (online) 1531-135X
    ISSN 1530-7026
    DOI 10.3758/s13415-021-00917-6
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    Zs.A 5947: Show issues Location:
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  3. Article ; Online: Acute stress alters probabilistic reversal learning in healthy male adults.

    Wieland, Lara / Ebrahimi, Claudia / Katthagen, Teresa / Panitz, Martin / Luettgau, Lennart / Heinz, Andreas / Schlagenhauf, Florian / Sjoerds, Zsuzsika

    The European journal of neuroscience

    2023  Volume 57, Issue 5, Page(s) 824–839

    Abstract: Behavioural adaptation is a fundamental cognitive ability, ensuring survival by allowing for flexible adjustment to changing environments. In laboratory settings, behavioural adaptation can be measured with reversal learning paradigms requiring agents to ...

    Abstract Behavioural adaptation is a fundamental cognitive ability, ensuring survival by allowing for flexible adjustment to changing environments. In laboratory settings, behavioural adaptation can be measured with reversal learning paradigms requiring agents to adjust reward learning to stimulus-action-outcome contingency changes. Stress is found to alter flexibility of reward learning, but effect directionality is mixed across studies. Here, we used model-based functional MRI (fMRI) in a within-subjects design to investigate the effect of acute psychosocial stress on flexible behavioural adaptation. Healthy male volunteers (n = 28) did a reversal learning task during fMRI in two sessions, once after the Trier Social Stress Test (TSST), a validated psychosocial stress induction method, and once after a control condition. Stress effects on choice behaviour were investigated using multilevel generalized linear models and computational models describing different learning processes that potentially generated the data. Computational models were fitted using a hierarchical Bayesian approach, and model-derived reward prediction errors (RPE) were used as fMRI regressors. We found that acute psychosocial stress slightly increased correct response rates. Model comparison revealed that double-update learning with altered choice temperature under stress best explained the observed behaviour. In the brain, model-derived RPEs were correlated with BOLD signals in striatum and ventromedial prefrontal cortex (vmPFC). Striatal RPE signals for win trials were stronger during stress compared with the control condition. Our study suggests that acute psychosocial stress could enhance reversal learning and RPE brain responses in healthy male participants and provides a starting point to explore these effects further in a more diverse population.
    MeSH term(s) Humans ; Male ; Adult ; Reversal Learning/physiology ; Bayes Theorem ; Brain/diagnostic imaging ; Cognition/physiology ; Prefrontal Cortex/diagnostic imaging ; Reward ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-02-15
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645180-9
    ISSN 1460-9568 ; 0953-816X
    ISSN (online) 1460-9568
    ISSN 0953-816X
    DOI 10.1111/ejn.15916
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2548: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Functional connectivity alterations between default mode network and occipital cortex in patients with obsessive-compulsive disorder (OCD)

    Tal Geffen / Jonathan Smallwood / Carsten Finke / Sebastian Olbrich / Zsuzsika Sjoerds / Florian Schlagenhauf

    NeuroImage: Clinical, Vol 33, Iss , Pp 102915- (2022)

    2022  

    Abstract: Altered brain network connectivity is a potential biomarker for obsessive–compulsive disorder (OCD). A meta-analysis of resting-state MRI studies by Gürsel et al. (2018) described altered functional connectivity in OCD patients within and between the ... ...

    Abstract Altered brain network connectivity is a potential biomarker for obsessive–compulsive disorder (OCD). A meta-analysis of resting-state MRI studies by Gürsel et al. (2018) described altered functional connectivity in OCD patients within and between the default mode network (DMN), the salience network (SN), and the frontoparietal network (FPN), as well as evidence for aberrant fronto-striatal circuitry. Here, we tested the replicability of these meta-analytic rsfMRI findings by measuring functional connectivity during resting-state fMRI in a new sample of OCD patients (n = 24) and matched controls (n = 33).We performed seed-to-voxel analyses using 30 seed regions from the prior meta-analysis. OCD patients showed reduced functional connectivity between the SN and the DMN compared to controls, replicating previous findings. We did not observe significant group differences of functional connectivity within the DMN, SN, nor FPN. Additionally, we observed reduced connectivity between the visual network to both the DMN and SN in OCD patients, in particular reduced functional connectivity between lateral parietal seeds and the left inferior lateral occipital pole. Furthermore, the right lateral parietal seed (associated with the DMN) was more strongly correlated with a cluster in the right lateral occipital cortex and precuneus (a region partly overlapping with the Dorsal Attentional Network (DAN)) in patients. Importantly, this latter finding was positively correlated to OCD symptom severity.Overall, our study partly replicated prior meta-analytic findings, highlighting hypoconnectivity between SN and DMN as a potential biomarker for OCD. Furthermore, we identified changes between the SN and the DMN with the visual network. This suggests that abnormal connectivity between cortex regions associated with abstract functions (transmodal regions such as the DMN), and cortex regions associated with constrained neural processing (unimodal regions such as the visual cortex), may be important in OCD.
    Keywords OCD ; Resting-state fMRI ; Seed analysis ; Functional connectivity ; Neuropsychiatry ; Computer applications to medicine. Medical informatics ; R858-859.7 ; Neurology. Diseases of the nervous system ; RC346-429
    Subject code 616
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Attentional blink and putative noninvasive dopamine markers: Two experiments to consolidate possible associations.

    Trutti, Anne Charlotte / Sjoerds, Zsuzsika / Hommel, Bernhard

    Cognitive, affective & behavioral neuroscience

    2019  Volume 19, Issue 6, Page(s) 1444–1457

    Abstract: Adaptive behavioral control involves a balance between top-down persistence and flexible updating of goals under changing demands. According to the metacontrol state model (MSM), this balance emerges from the interaction between the frontal and the ... ...

    Abstract Adaptive behavioral control involves a balance between top-down persistence and flexible updating of goals under changing demands. According to the metacontrol state model (MSM), this balance emerges from the interaction between the frontal and the striatal dopaminergic system. The attentional blink (AB) task has been argued to tap into the interaction between persistence and flexibility, as it reflects overpersistence-the too-exclusive allocation of attentional resources to the processing of the first of two consecutive targets. Notably, previous studies are inconclusive about the association between the AB and noninvasive proxies of dopamine including the spontaneous eye blink rate (sEBR), which allegedly assesses striatal dopamine levels. We aimed to substantiate and extend previous attempts to predict individual sizes of the AB in two separate experiments with larger sample sizes (N = 71 & N = 65) by means of noninvasive behavioral and physiological proxies of dopamine (DA), such as sEBR and mood measures, which are likely to reflect striatal dopamine levels, and color discrimination, which has been argued to tap into the frontal dopamine levels. Our findings did not confirm the prediction that AB size covaries with sEBR, mood, or color discrimination. The implications of this inconsistency with previous observations are discussed.
    MeSH term(s) Affect/physiology ; Attentional Blink/physiology ; Blinking/physiology ; Color ; Discrimination, Psychological/physiology ; Dopamine/physiology ; Female ; Humans ; Male ; Young Adult
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2019-08-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2029088-3
    ISSN 1531-135X ; 1530-7026
    ISSN (online) 1531-135X
    ISSN 1530-7026
    DOI 10.3758/s13415-019-00717-z
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5947: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Functional connectivity alterations between default mode network and occipital cortex in patients with obsessive-compulsive disorder (OCD).

    Geffen, Tal / Smallwood, Jonathan / Finke, Carsten / Olbrich, Sebastian / Sjoerds, Zsuzsika / Schlagenhauf, Florian

    NeuroImage. Clinical

    2021  Volume 33, Page(s) 102915

    Abstract: Altered brain network connectivity is a potential biomarker for obsessive-compulsive disorder (OCD). A meta-analysis of resting-state MRI studies by Gürsel et al. (2018) described altered functional connectivity in OCD patients within and between the ... ...

    Abstract Altered brain network connectivity is a potential biomarker for obsessive-compulsive disorder (OCD). A meta-analysis of resting-state MRI studies by Gürsel et al. (2018) described altered functional connectivity in OCD patients within and between the default mode network (DMN), the salience network (SN), and the frontoparietal network (FPN), as well as evidence for aberrant fronto-striatal circuitry. Here, we tested the replicability of these meta-analytic rsfMRI findings by measuring functional connectivity during resting-state fMRI in a new sample of OCD patients (n = 24) and matched controls (n = 33). We performed seed-to-voxel analyses using 30 seed regions from the prior meta-analysis. OCD patients showed reduced functional connectivity between the SN and the DMN compared to controls, replicating previous findings. We did not observe significant group differences of functional connectivity within the DMN, SN, nor FPN. Additionally, we observed reduced connectivity between the visual network to both the DMN and SN in OCD patients, in particular reduced functional connectivity between lateral parietal seeds and the left inferior lateral occipital pole. Furthermore, the right lateral parietal seed (associated with the DMN) was more strongly correlated with a cluster in the right lateral occipital cortex and precuneus (a region partly overlapping with the Dorsal Attentional Network (DAN)) in patients. Importantly, this latter finding was positively correlated to OCD symptom severity. Overall, our study partly replicated prior meta-analytic findings, highlighting hypoconnectivity between SN and DMN as a potential biomarker for OCD. Furthermore, we identified changes between the SN and the DMN with the visual network. This suggests that abnormal connectivity between cortex regions associated with abstract functions (transmodal regions such as the DMN), and cortex regions associated with constrained neural processing (unimodal regions such as the visual cortex), may be important in OCD.
    MeSH term(s) Brain ; Brain Mapping ; Default Mode Network ; Humans ; Magnetic Resonance Imaging ; Neural Pathways/diagnostic imaging ; Obsessive-Compulsive Disorder/diagnostic imaging ; Occipital Lobe/diagnostic imaging
    Language English
    Publishing date 2021-12-16
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701571-3
    ISSN 2213-1582 ; 2213-1582
    ISSN (online) 2213-1582
    ISSN 2213-1582
    DOI 10.1016/j.nicl.2021.102915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: How metacontrol biases and adaptivity impact performance in cognitive search tasks.

    Mekern, Vera N / Sjoerds, Zsuzsika / Hommel, Bernhard

    Cognition

    2018  Volume 182, Page(s) 251–259

    Abstract: Cognitive control requires a balance between persistence and flexibility. We studied inter- and intraindividual differences in the metacontrol bias towards persistence or flexibility in cognitive search tasks from various cognitive domains that require ... ...

    Abstract Cognitive control requires a balance between persistence and flexibility. We studied inter- and intraindividual differences in the metacontrol bias towards persistence or flexibility in cognitive search tasks from various cognitive domains that require continuous switching between persistence and flexibility. For each task, clustering and switching scores were derived to assess persistence and flexibility, respectively, as well as a total performance score to reflect general performance. We compared two, not mutually exclusive accounts according to which the balance between clustering and switching scores is affected by (1) individual, trait-like metacontrol biases towards persistence or flexibility and/or (2) the metacontrol adaptivity to bias states according to changing situational demands. We found that clustering and switching scores failed to generalize across tasks. However, clustering and switching were inversely related and predicted the total performance scores in most of the tasks, which in turn partially generalized across tasks and task domains. We conclude that metacontrol-biases towards persistence or flexibility can be adapted easily to specific task demands and individual resources, possibly overwriting individual metacontrol trait biases. Moreover, we suggest that total performance scores might serve to measure metacontrol adaptivity in future studies if task-restrictions and resources are known and/or well balanced.
    MeSH term(s) Adaptation, Physiological/physiology ; Adult ; Executive Function/physiology ; Female ; Humans ; Male ; Metacognition/physiology ; Models, Psychological ; Psychomotor Performance/physiology ; Young Adult
    Language English
    Publishing date 2018-10-24
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1499940-7
    ISSN 1873-7838 ; 0010-0277
    ISSN (online) 1873-7838
    ISSN 0010-0277
    DOI 10.1016/j.cognition.2018.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acute and past subjective stress influence working memory and related neural substrates.

    Luettgau, Lennart / Schlagenhauf, Florian / Sjoerds, Zsuzsika

    Psychoneuroendocrinology

    2018  Volume 96, Page(s) 25–34

    Abstract: Stress has been proposed to affect cognitive control capacities, including working memory (WM) maintenance. This effect may depend on variability in stress reactivity and past subjective stress. However, as most studies employed between-subjects designs, ...

    Abstract Stress has been proposed to affect cognitive control capacities, including working memory (WM) maintenance. This effect may depend on variability in stress reactivity and past subjective stress. However, as most studies employed between-subjects designs, evidence for within-subject stress effects remains scarce. To understand the role of intra-individual stress effects on WM, we adopted a within-subject design to study how acute stress, variability in stress reactivity, and past subjective stress influence behavioral and neural WM mechanisms. Thirty-four healthy males performed a WM task during functional magnetic resonance imaging (fMRI) in a control versus acute stress condition following the Trier Social Stress Test, a validated psychosocial stressor method. We tested for stress effects on WM performance and related neural activation by associating them with individual acute stress responsivity and past subjective stress experience using retrospective self-report questionnaires. We found no evidence of an effect of acute stress or related stress-reactivity on intra-individual WM performance. However, past subjective stress negatively influenced acute stress-induced changes to WM. On the neural level, acute stress reduced WM-related activation in the dorsolateral prefrontal cortex (dlPFC). The observed negative influence of inter-individual variability in past subjective stress experience on changes in WM performance, suggests that past subjective stress might induce vulnerability for impairing effects of acute stress on cognitive functioning. Because acute stress reduced WM-related dlPFC activation while WM performance remained unaffected, acute stress might boost neural processing efficiency in this group of high performing healthy individuals. Our study suggests that measures of past subjective stress should be considered when studying and interpreting the effects of acute stress on cognition.
    MeSH term(s) Adult ; Brain/physiology ; Brain Mapping/methods ; Cognition/physiology ; Healthy Volunteers ; Humans ; Hydrocortisone/analysis ; Magnetic Resonance Imaging/methods ; Male ; Memory, Short-Term/physiology ; Nerve Net/physiology ; Neural Pathways/physiology ; Prefrontal Cortex/physiology ; Retrospective Studies ; Saliva/chemistry ; Self Report ; Stress, Psychological/physiopathology ; Surveys and Questionnaires ; Young Adult
    Chemical Substances Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2018-05-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 197636-9
    ISSN 1873-3360 ; 0306-4530
    ISSN (online) 1873-3360
    ISSN 0306-4530
    DOI 10.1016/j.psyneuen.2018.05.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1235: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Cognitive Control of Working Memory: A Model-Based Approach.

    Boag, Russell J / Stevenson, Niek / van Dooren, Roel / Trutti, Anne C / Sjoerds, Zsuzsika / Forstmann, Birte U

    Brain sciences

    2021  Volume 11, Issue 6

    Abstract: Working memory (WM)-based decision making depends on a number of cognitive control processes that control the flow of information into and out of WM and ensure that only relevant information is held active in WM's limited-capacity store. Although ... ...

    Abstract Working memory (WM)-based decision making depends on a number of cognitive control processes that control the flow of information into and out of WM and ensure that only relevant information is held active in WM's limited-capacity store. Although necessary for successful decision making, recent work has shown that these control processes impose performance costs on both the speed and accuracy of WM-based decisions. Using the reference-back task as a benchmark measure of WM control, we conducted evidence accumulation modeling to test several competing explanations for six benchmark empirical performance costs. Costs were driven by a combination of processes, running outside of the decision stage (longer non-decision time) and showing the inhibition of the prepotent response (lower drift rates) in trials requiring WM control. Individuals also set more cautious response thresholds when expecting to update WM with new information versus maintain existing information. We discuss the promise of this approach for understanding cognitive control in WM-based decision making.
    Language English
    Publishing date 2021-05-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci11060721
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  10. Article: Functional connectivity alterations between default mode network and occipital cortex in patients with obsessive-compulsive disorder (OCD)

    Geffen, Tal / Smallwood, Jonathan / Finke, Carsten / Olbrich, Sebastian / Sjoerds, Zsuzsika / Schlagenhauf, Florian

    NeuroImage: Clinical

    2022  

    Abstract: Altered brain network connectivity is a potential biomarker for obsessive-compulsive disorder (OCD). A meta-analysis of resting-state MRI studies by Gursel et al. (2018) described altered functional connectivity in OCD patients within and between the ... ...

    Title translation Funktionelle Konnektivitätsveränderungen zwischen dem Standardmodus-Netzwerk und dem okzipitalen Kortex bei Patienten mit Zwangsstörungen (OCD) (DeepL)
    Abstract Altered brain network connectivity is a potential biomarker for obsessive-compulsive disorder (OCD). A meta-analysis of resting-state MRI studies by Gursel et al. (2018) described altered functional connectivity in OCD patients within and between the default mode network (DMN), the salience network (SN), and the frontoparietal network (FPN), as well as evidence for aberrant fronto-striatal circuitry. Here, we tested the replicability of these meta-analytic rsfMRI findings by measuring functional connectivity during resting-state fMRI in a new sample of OCD patients (n = 24) and matched controls (n = 33). We performed seed-to-voxel analyses using 30 seed regions from the prior meta-analysis. OCD patients showed reduced functional connectivity between the SN and the DMN compared to controls, replicating previous findings. We did not observe significant group differences of functional connectivity within the DMN, SN, nor FPN. Additionally, we observed reduced connectivity between the visual network to both the DMN and SN in OCD patients, in particular reduced functional connectivity between lateral parietal seeds and the left inferior lateral occipital pole. Furthermore, the right lateral parietal seed (associated with the DMN) was more strongly correlated with a cluster in the right lateral occipital cortex and precuneus (a region partly overlapping with the Dorsal Attentional Network (DAN)) in patients. Importantly, this latter finding was positively correlated to OCD symptom severity. Overall, our study partly replicated prior meta-analytic findings, highlighting hypoconnectivity between SN and DMN as a potential biomarker for OCD. Furthermore, we identified changes between the SN and the DMN with the visual network. This suggests that abnormal connectivity between cortex regions associated with abstract functions (transmodal regions such as the DMN), and cortex regions associated with constrained neural processing (unimodal regions such as the visual cortex), may be important in OCD.
    Keywords Biological Neural Networks ; Biologische Neuronale Netze ; Brain Connectivity ; Default Mode Network ; Konnektivität (Gehirn) ; Obsessive Compulsive Disorder ; Occipital Lobe ; Okzipitallappen (Gehirn) ; Ruhezustandsnetzwerk ; Zwangsstörung
    Language English
    Document type Article
    ZDB-ID 2701571-3
    ISSN 2213-1582
    ISSN 2213-1582
    DOI 10.1016/j.nicl.2021.102915
    Database PSYNDEX

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