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  1. Article ; Online: Gone with the Wind.

    Alchin, David

    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

    2020  Volume 28, Issue 6, Page(s) 636–638

    Abstract: Objective: If the narrative of "coronavirus" has an underlying theme, it may perhaps for some be one of survival, whilst for others, the theme might be suffering. The recurring motif of survival has continued throughout history, yet for the first time ... ...

    Abstract Objective: If the narrative of "coronavirus" has an underlying theme, it may perhaps for some be one of survival, whilst for others, the theme might be suffering. The recurring motif of survival has continued throughout history, yet for the first time the sum of all fears has amounted to a run on the bare essentials. This paper seeks to offer an alternative formulation of "panic buying," with references to literature, philosophy, and contemporary neurobiology.
    Conclusion: The bare essentials disappeared perhaps as part of some self-fulfilling prophecy: the supermarkets became bare because others inadvertently lead us to believe they would become bare. The contagion model of emotional propagation provides a psychological model of how "panic buying" by an individual might lead to the replication of panic in an observer. The Polyvagal Theory further informs us of how the threat posed by the pandemic primes our limbic system to perceive danger, and explains how witnessing others engaging in fight-flight responses might evoke a fearful affect in an observer. In the end, it is perhaps through Nietzsche's study of classical tragedy that we may find some meaning to the pandemic, allowing our collective lived experience to serve as a template for growth.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/psychology ; Disaster Victims/psychology ; Emotional Adjustment ; Fear ; Humans ; Neurobiology ; Pandemics ; Panic ; Pneumonia, Viral/psychology ; Psychological Theory ; Psychology, Social ; SARS-CoV-2 ; Survival/psychology
    Keywords covid19
    Language English
    Publishing date 2020-07-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2213198-X
    ISSN 1440-1665 ; 1039-8562
    ISSN (online) 1440-1665
    ISSN 1039-8562
    DOI 10.1177/1039856220936144
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  2. Article ; Online: 'Vaping psychosis': Ultra-acute onset of severe, persisting and unusual psychotic symptoms following first-time cannabis vaping in a previously well individual.

    Alchin, David R

    The Australian and New Zealand journal of psychiatry

    2020  Volume 54, Issue 8, Page(s) 848

    MeSH term(s) Adult ; Cannabis/adverse effects ; Humans ; Marijuana Abuse/complications ; Prazosin ; Psychotic Disorders/drug therapy ; Randomized Controlled Trials as Topic ; Stress Disorders, Post-Traumatic ; Vaping/adverse effects
    Chemical Substances Prazosin (XM03YJ541D)
    Language English
    Publishing date 2020-02-07
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 221140-3
    ISSN 1440-1614 ; 0004-8674
    ISSN (online) 1440-1614
    ISSN 0004-8674
    DOI 10.1177/0004867419900320
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    Zs.A 856: Show issues Location:
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  3. Article ; Online: Gone with the Wind.

    Alchin, David

    2020  

    Abstract: Objective: If the narrative of “coronavirus” has an underlying theme, it may perhaps for some be one of survival, whilst for others, the theme might be suffering. The recurring motif of survival has continued throughout history, yet for the first time ... ...

    Abstract Objective: If the narrative of “coronavirus” has an underlying theme, it may perhaps for some be one of survival, whilst for others, the theme might be suffering. The recurring motif of survival has continued throughout history, yet for the first time the sum of all fears has amounted to a run on the bare essentials. This paper seeks to offer an alternative formulation of “panic buying,” with references to literature, philosophy, and contemporary neurobiology. Conclusion: The bare essentials disappeared perhaps as part of some self-fulfilling prophecy: the supermarkets became bare because others inadvertently lead us to believe they would become bare. The contagion model of emotional propagation provides a psychological model of how “panic buying” by an individual might lead to the replication of panic in an observer. The Polyvagal Theory further informs us of how the threat posed by the pandemic primes our limbic system to perceive danger, and explains how witnessing others engaging in fight-flight responses might evoke a fearful affect in an observer. In the end, it is perhaps through Nietzsche’s study of classical tragedy that we may find some meaning to the pandemic, allowing our collective lived experience to serve as a template for growth.
    Keywords COVID-19 ; Coronavirus ; covid19
    Language English
    Publishing date 2020-01-01
    Publishing country au
    Document type Article ; Online
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  4. Article ; Online: A case of iatrogenic psychosis in the context of inappropriate prescribing for COVID-19.

    Alchin, David R / Ghaly, Sara

    The Australian and New Zealand journal of psychiatry

    2021  Volume 56, Issue 7, Page(s) 873–874

    MeSH term(s) COVID-19 ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Iatrogenic Disease ; Inappropriate Prescribing ; Psychotic Disorders/drug therapy
    Language English
    Publishing date 2021-12-28
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 221140-3
    ISSN 1440-1614 ; 0004-8674
    ISSN (online) 1440-1614
    ISSN 0004-8674
    DOI 10.1177/00048674211065364
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  5. Article ; Online: HIV vaccine development: an exploratory review of the trials and tribulations.

    Alchin, David Rhys

    Immunologic research

    2014  Volume 60, Issue 1, Page(s) 35–37

    Abstract: While advances have been made in some areas, more often than not attempts at vaccine development against the human immunodeficiency virus only serve to highlight gaps in our knowledge of host immunity. While numerous approaches have been explored, to ... ...

    Abstract While advances have been made in some areas, more often than not attempts at vaccine development against the human immunodeficiency virus only serve to highlight gaps in our knowledge of host immunity. While numerous approaches have been explored, to control infection, an HIV vaccine will need to be able to induce production of neutralizing antibodies and a cytotoxic T cell response in order to prevent the formation of the CD4+ T cell viral reservoir. However, challenges still remain for the development of an HIV vaccine. Incomplete knowledge of host immunity lies at the core of the tribulations lying in the face of effective vaccine development.
    MeSH term(s) AIDS Vaccines ; Antibodies, Neutralizing/immunology ; HIV Antibodies/immunology ; HIV Antigens/immunology ; Humans ; T-Lymphocytes, Cytotoxic/immunology
    Chemical Substances AIDS Vaccines ; Antibodies, Neutralizing ; HIV Antibodies ; HIV Antigens
    Language English
    Publishing date 2014-05-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632857-x
    ISSN 1559-0755 ; 0257-277X
    ISSN (online) 1559-0755
    ISSN 0257-277X
    DOI 10.1007/s12026-014-8551-y
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    Zs.A 1755: Show issues Location:
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  6. Article: Ingenol mebutate: a succinct review of a succinct therapy.

    Alchin, David Rhys

    Dermatology and therapy

    2014  Volume 4, Issue 2, Page(s) 157–164

    Abstract: Background: Ingenol mebutate is a newly approved topical field therapy for actinic keratosis (AK). It has a dual mechanism of action comprising of a rapid induction of necrosis that specifically targets dysplastic cells, as well as neutrophil-mediated ... ...

    Abstract Background: Ingenol mebutate is a newly approved topical field therapy for actinic keratosis (AK). It has a dual mechanism of action comprising of a rapid induction of necrosis that specifically targets dysplastic cells, as well as neutrophil-mediated immunostimulatory effects. Such a dual mechanism allows for this agent to clear AK lesions in as little as two to three daily applications, thus providing for improved treatment outcomes and patient satisfaction.
    Review: Given that this is a new dermatologic therapy, this review summarizes the key literature surrounding this agent. This review covers the indications for use, mechanisms of action, method of administration, efficacy and safety profile and important drug interactions of ingenol mebutate.
    Conclusions: Ingenol mebutate should be considered a highly relevant field therapy for AK and the prevention of progression to squamous cell carcinoma.
    Language English
    Publishing date 2014-08-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2680284-3
    ISSN 2190-9172 ; 2193-8210
    ISSN (online) 2190-9172
    ISSN 2193-8210
    DOI 10.1007/s13555-014-0061-2
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  7. Article: Sarcopenia: describing rather than defining a condition.

    Alchin, David Rhys

    Journal of cachexia, sarcopenia and muscle

    2014  Volume 5, Issue 4, Page(s) 265–268

    Abstract: Background: Traditional definitions of sarcopenia have described an aging-associated disorder roughly defined as muscle mass two standard deviations below the young adult demographic. In an effort to clear the ambiguity pertaining to such descriptions, ... ...

    Abstract Background: Traditional definitions of sarcopenia have described an aging-associated disorder roughly defined as muscle mass two standard deviations below the young adult demographic. In an effort to clear the ambiguity pertaining to such descriptions, two international bodies have put forth working definitions of sarcopenia, namely The Society of Sarcopenia, Cachexia and Wasting Disorders in 2011, and The European Working Group on Sarcopenia in Older People in 2009.
    Review: This paper will look at the current zeitgeist of sarcopenia through a range of studies and will argue that what we have is an amalgamated and often conflicted description, rather than a definition, of the sarcopenic condition. Herein, we will consider whether such descriptions of sarcopenia should center on the consideration of the neuromuscular junction (NMJ) rather than describing the condition more in terms of muscular pathology.
    Conclusion: Consideration was given to studies of the NMJ to advance the idea that present notions of the sarcopenic condition are incomplete and that at its' core, sarcopenia is an age-related disorder of the NMJ.
    Language English
    Publishing date 2014-08-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2586864-0
    ISSN 2190-6009 ; 2190-5991
    ISSN (online) 2190-6009
    ISSN 2190-5991
    DOI 10.1007/s13539-014-0156-8
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  8. Article ; Online: Love in the time of Corona.

    Alchin, David / McLean, Loyola / Korner, Anthony

    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

    2020  Volume 28, Issue 5, Page(s) 521–523

    Abstract: Objective: As the world struggles to come to terms with "corona," we find our collective experience to be entirely alien, struggling to find meaning in the forms of feeling being evoked. When words cannot provide meaning to experience, metaphor is often ...

    Abstract Objective: As the world struggles to come to terms with "corona," we find our collective experience to be entirely alien, struggling to find meaning in the forms of feeling being evoked. When words cannot provide meaning to experience, metaphor is often utilized.
    Conclusions: Words like "love" are informed autobiographically as "growing words," with no rules defining their use. The significance of "love" to an individual is created through personal history, such that sophisticated understanding is only constructed following a lifetime of experience. "Corona" is perhaps a growing word; we cannot yet grasp its meaning in the face of
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/psychology ; Emotions ; Humans ; Love ; Metaphor ; Pandemics ; Pneumonia, Viral/psychology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2213198-X
    ISSN 1440-1665 ; 1039-8562
    ISSN (online) 1440-1665
    ISSN 1039-8562
    DOI 10.1177/1039856220936142
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  9. Article: Love in the time of Corona

    Alchin, David / McLean, Loyola / Korner, Anthony

    Australas Psychiatry

    Abstract: OBJECTIVE: As the world struggles to come to terms with "corona," we find our collective experience to be entirely alien, struggling to find meaning in the forms of feeling being evoked. When words cannot provide meaning to experience, metaphor is often ... ...

    Abstract OBJECTIVE: As the world struggles to come to terms with "corona," we find our collective experience to be entirely alien, struggling to find meaning in the forms of feeling being evoked. When words cannot provide meaning to experience, metaphor is often utilized. CONCLUSIONS: Words like "love" are informed autobiographically as "growing words," with no rules defining their use. The significance of "love" to an individual is created through personal history, such that sophisticated understanding is only constructed following a lifetime of experience. "Corona" is perhaps a growing word; we cannot yet grasp its meaning in the face of cólera (passion) and pati (suffering) informing our collective traumatic script. Psychiatrists should aim to focus on the positive forms of feeling emerging during the pandemic, in order to be better equipped to meet the impending "second wave" of mental health complications.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #690191
    Database COVID19

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  10. Article ; Online: Love in the time of Corona

    Alchin, David / McLean, Loyola / Korner, Anthony

    2020  

    Abstract: OBJECTIVE: As the world struggles to come to terms with "corona," we find our collective experience to be entirely alien, struggling to find meaning in the forms of feeling being evoked. When words cannot provide meaning to experience, metaphor is often ... ...

    Abstract OBJECTIVE: As the world struggles to come to terms with "corona," we find our collective experience to be entirely alien, struggling to find meaning in the forms of feeling being evoked. When words cannot provide meaning to experience, metaphor is often utilized. CONCLUSIONS: Words like "love" are informed autobiographically as "growing words," with no rules defining their use. The significance of "love" to an individual is created through personal history, such that sophisticated understanding is only constructed following a lifetime of experience. "Corona" is perhaps a growing word; we cannot yet grasp its meaning in the face of cólera (passion) and pati (suffering) informing our collective traumatic script. Psychiatrists should aim to focus on the positive forms of feeling emerging during the pandemic, in order to be better equipped to meet the impending "second wave" of mental health complications.
    Keywords COVID-19 ; Coronavirus ; covid19
    Language English
    Publishing date 2020-01-01
    Publishing country au
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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