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Article ; Online: Assessment of Pregnancy Follow-Ups For Cases Registered in a Family Health Center

Halil Alper Aslan / Raziye Desdicioglu / Gülin Feykan Yeğin

Ankara Medical Journal, Vol 22, Iss 1, Pp 1-

2022 Volume 12

Abstract: INTRODUCTION: Our research aimed to evaluate the antenatal care (ANC) and pregnancy outcomes for pregnant cases registered with a family practice unit providing primary health services. METHODS: Data for 385 pregnant cases aged 18 to 40 years registered ... ...

Abstract	INTRODUCTION: Our research aimed to evaluate the antenatal care (ANC) and pregnancy outcomes for pregnant cases registered with a family practice unit providing primary health services. METHODS: Data for 385 pregnant cases aged 18 to 40 years registered with a family health center from 15/07/2010 to 01/02/2019 were screened from the "Family Practice Information Management System" database. Data regarding antenatal visits were statistically investigated and the p-value below 0.05 was accepted as significant. RESULTS: The mean age was 28.66+-5.36 years. The mean pregnancy week of first attendance was 9.59+-5.52. Of pregnant cases, 89.61% received iron, 47.79% vitamin D and 63.63% folic acid supplements. Of the patients, 81.81% had the first trimester, and 76.88% had second-trimester screening tests. 71.42% of patients had gestational diabetes screening, and 88.83% had detailed ultrasonography. 78.44% of patients had tetanus-diphtheria vaccination, while no pregnant case had influenza vaccination. The age and gravida did not affect receiving ANC, vitamin D, iron supplementation and tetanus-diphtheria vaccination status. Vitamin D use was higher in groups receiving education compared to those not receiving education. When the educated group was assessed among themselves, the use of supplements reduced as the educational level increased. DISCUSSION AND CONCLUSION: There is a need to increase referrals for iron, vitamin D, and folic acid supplementation and for screening during antenatal follow-up. The tetanus-diphtheria vaccination rate was observed to be lower than ideal. Additionally, it appears administration of seasonal flu vaccines is deficient, and necessary steps should be taken to reduce concerns related to vaccination.
Keywords	antenatal care ; family physician ; pregnancy ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	360
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Ankara Yildirim Beyazit University
Document type	Article ; Online
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Article: Is postmenopausal endometrial fluid collection alone a risk factor for endometrial cancer?

Yegin Akcay, Gulin Feykan / Tas, Emre Erdem / Yavuz, Ayse Filiz

Pakistan journal of medical sciences

2018 Volume 34, Issue 1, Page(s) 54–57

Abstract: Objective: To determine the usefulness of single-layer, ultrasonographic measurement of endometrial fluid collection (EFC) volume to predict endometrial pathology in asymptomatic postmenopausal patients.: Methods: One hundred fifty asymptomatic ... ...

Abstract	Objective: To determine the usefulness of single-layer, ultrasonographic measurement of endometrial fluid collection (EFC) volume to predict endometrial pathology in asymptomatic postmenopausal patients. Methods: One hundred fifty asymptomatic postmenopausal women were analysed retrospectively from January 2012 to December 2016. After patients with endometrial hyperplasia/neoplasia were included in Group-I, and those with insufficient tissue, endometrial atrophy, or endometritis were included in Group-II; Groups one and two were compared with respect to primary (correlations between endometrial thickness and EFC volume) and secondary (correlations between demographic characteristics and EFC volume) outcomes. Results: There was no correlation between EFC volume and single-layer endometrial thickness ( Conclusion: Although a cutoff value for endometrial thickness and EFC volume could not be recommended based on our study findings, it should be noted that 2% is a clinically significant rate of malignancy. Thus, postmenopausal patients with EFC should be evaluated for endometrial sampling.
Language	English
Publishing date	2018-03-28
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.341.13990
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Article: Single-dose methotrexate for the treatment of ectopic pregnancy: Our experience from 2010 to 2015.

Tas, Emre Erdem / Akcay, Gulin Feykan Yegin / Avsar, Ayse Filiz

Pakistan journal of medical sciences

2016 Volume 33, Issue 1, Page(s) 13–17

Abstract: Objective: To evaluate the success of systemic single-dose methotrexate (MTX) treatment in patients with ectopic pregnancy (EP) and to investigate factors related to treatment success.: Methods: This retrospective study had been performed in Yildirim ...

Abstract	Objective: To evaluate the success of systemic single-dose methotrexate (MTX) treatment in patients with ectopic pregnancy (EP) and to investigate factors related to treatment success. Methods: This retrospective study had been performed in Yildirim Beyazit University between January 2010 and December 2015. Demographic and clinical characteristics, ultrasonografic findings, pretreatment serum β-human chorionic gonadotropin (β-hCG) and progesterone levels of 58 patients with EP were retrieved from hospital records retrospectively. The patients were grouped according to MTX treatment success (response Results: Single-dose MTX-treatment was successful in 72.4% (42/58) of patients. The mean pretreatment β-hCG level was significantly lower in responders than in failures (2080 ± 2322 Conclusion: The success rate of single dose MTX in this study was 72.8 %, and we found that failure rate of MTX treatment was 8.45 times more in group of patients whose initial serum β-hCG values were above 2678 IU/L and 12 times more in patients with fetal cardiac activity.
Language	English
Publishing date	2016-07-08
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.331.11238
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Article ; Online: Do Meteorological Variations and Climate Changes Affect Hyperemesis Gravidarum?

Akgun, Nilufer / Misirligil, Selcuk / Yegin, Gülin Feykan / Keskin, H Levent / Yavuz, Ayse Filiz

Zeitschrift fur Geburtshilfe und Neonatologie

2022 Volume 226, Issue 5, Page(s) 304–310

Abstract: Background: To estimate a possible association between the effects of daily meteorological variation and climatological changes (temperature, air pressure, humidity, sunniness level) on pregnant women with hyperemesis gravidarum (HG) according to ... ...

Abstract	Background: To estimate a possible association between the effects of daily meteorological variation and climatological changes (temperature, air pressure, humidity, sunniness level) on pregnant women with hyperemesis gravidarum (HG) according to symptoms grade and hospitalization state. Methods: A retrospective study was conducted with 118 patients diagnosed and hospitalized with HG. HG patients were graded as mild, moderate, or severe according to the Pregnancy Unique Quantification of Emesis (PUQE-24) scale. Data regarding demographic characteristics, PUQE scale value, gestational week on hospitalization, hospital admission and discharge dates, weather conditions, daily meteorological values during hospitalization ( temperature, air pressure, humidity, sunniness level), seasonal averages, and daily changes were recorded. Weather records were obtained from the Ankara Meteorology General Directorate (Ankara, Turkey). Differences between groups were compared according to HG grade. Results: HG cases were classified as mild (33.1%), moderate (44.9%), or severe (22.0%). The number of hospitalization days significantly differed between these three groups (p<0.05). In contrast, no statistically significant differences were identified between the HG grade level groups in regard to humidity, pressure, temperature, and sunniness level data (p>0.05). In addition, no statistically significant relationship was identified between HG grades and seasonal conditions according to the chi-square test (p>0.05). Conclusion: Changes in the meteorological and climate values examined were independent of symptom severity and hospitalization rate for our HG patients. However, it is possible that climate changes occurring around the world may affect the pregnancy period and should be further investigated.
MeSH term(s)	Climate Change ; Female ; Hospitalization ; Humans ; Hyperemesis Gravidarum/diagnosis ; Hyperemesis Gravidarum/epidemiology ; Meteorology ; Pregnancy ; Retrospective Studies
Language	English
Publishing date	2022-06-30
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1226748-x
ISSN	1439-1651 ; 0300-967X ; 0948-2393 ; 1615-5300
ISSN (online)	1439-1651
ISSN	0300-967X ; 0948-2393 ; 1615-5300
DOI	10.1055/a-1808-1800
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Article ; Online: The rate of SARS-CoV-2 positivity in asymptomatic pregnant women admitted to hospital for delivery

Tanacan, Atakan / Erol, Seyit Ahmet / Turgay, Batuhan / Anuk, Ali Taner / Secen, Elcin Islek / Yegin, Gulin Feykan / Ozyer, Sebnem / Kirca, Fisun / Dinc, Bedia / Unlu, Serpil / Yapar Eyi, Elif Gul / Keskin, Huseyin Levent / Sahin, Dilek / Surel, Aziz Ahmet / Tekin, Ozlem Moraloglu

European Journal of Obstetrics & Gynecology and Reproductive Biology

Experience of a pandemic center in Turkey

2020 Volume 253, Page(s) 31–34

Keywords	Obstetrics and Gynaecology ; Reproductive Medicine ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	190605-7
ISSN	1872-7654 ; 0301-2115 ; 0028-2243
ISSN (online)	1872-7654
ISSN	0301-2115 ; 0028-2243
DOI	10.1016/j.ejogrb.2020.07.051
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Article ; Online: The rate of SARS-CoV-2 positivity in asymptomatic pregnant women admitted to hospital for delivery: Experience of a pandemic center in Turkey.

European journal of obstetrics, gynecology, and reproductive biology

2020 Volume 253, Page(s) 31–34

Abstract: Objective: To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in asymptomatic pregnant women admitted to hospital for delivery in a Turkish pandemic center.: Study design: This prospective cohort study ... ...

Abstract	Objective: To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in asymptomatic pregnant women admitted to hospital for delivery in a Turkish pandemic center. Study design: This prospective cohort study was conducted in Ankara City Hospital between April, 15, 2020 and June, 5, 2020. A total of 206 asymptomatic pregnant women (103 low-risk pregnant women without any defined risk factor and 103 high-risk pregnant women) were screened for SARS-CoV-2 positivity upon admission to hospital for delivery. Detection of SARS-CoV2 in nasopharyngeal and oropharyngeal samples was performed by Real Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) method targeting RdRp (RNA dependent RNA polymerase) gene. Two groups were compared in terms of demographic features, clinical characteristics and SARS-CoV-2 positivity. Results: Three of the 206 pregnant women participating in the study had positive RT-PCR tests (1.4 %) and all positive cases were in the high-risk pregnancy group. Although, one case in the high-risk pregnancy group had developed symptoms highly suspicious for COVID-19, two repeated RT-PCR tests were negative. SARS-CoV-2 RT-PCR positivity rate was significantly higher in the high-risk pregnancy group (2.9 % vs 0%, p = 0.04). Conclusion: Healthcare professionals should be cautious in the labor and delivery of high-risk pregnant women during the pandemic period and universal testing for COVID-19 may be considered in selected populations.
MeSH term(s)	Adult ; Asymptomatic Infections/epidemiology ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Female ; Hospitalization/statistics & numerical data ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/epidemiology ; Pregnancy Complications, Infectious/virology ; Prenatal Diagnosis/methods ; Prenatal Diagnosis/statistics & numerical data ; Prospective Studies ; Risk Factors ; SARS-CoV-2 ; Turkey/epidemiology
Chemical Substances	COVID-19 Vaccines ; Covid-19 aAPC vaccine
Keywords	covid19
Language	English
Publishing date	2020-07-30
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	190605-7
ISSN	1872-7654 ; 0301-2115 ; 0028-2243
ISSN (online)	1872-7654
ISSN	0301-2115 ; 0028-2243
DOI	10.1016/j.ejogrb.2020.07.051
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Article: Vaginoplasty Using Human Amniotic Membranes A Report of Five Patients.

Avsar, Ayse Filiz / Tas, Emre Erdem / Keskin, Hiiseyin Levent / Yeğin, Gülin Feykan

The Journal of reproductive medicine

2018 Volume 61, Issue 9-10, Page(s) 483–488

Abstract: Objective: To present our experiences with an innovative surgical approach for vaginal agenesis that uses amnion as the allograft to create a functional neovagina.: Study design: This study involved 5 patients with diagnosed vaginal agenesis. One ... ...

Abstract	Objective: To present our experiences with an innovative surgical approach for vaginal agenesis that uses amnion as the allograft to create a functional neovagina. Study design: This study involved 5 patients with diagnosed vaginal agenesis. One patient had karyotype 46,XY and was diagnosed with complete androgen insensitivity syn- drome, whereas the others had karyotype 46,XX and were diagnosed with Mayer-Rokitansky-Kiister-Hauser syndrome. All patients underwent Mclndoe vagino- plasty using amnion and were followed up at 2 weeks, 3 months, 6 months, and 12 months postsurgery. Functionality of the neovagina was assessed by Rosen Female Sexual Function Index (FSFI) questionnaire. Results: At the 12-month follow-up 1 patient report- ed. an inability to use the vaginal dilator effectively; for the other 4 patients the mean depth of the neovagina was 9.5 cm and the mean width was 3.5 cm. The mean overall FSFI score was 28.3. Conclusion: McIndoe vaginoplasty is a simple, safe, and quick operative method that results in a ftnctional vagina. The amnion is a suitable material to apply to the surface of the neovagina because it is readily avail- able and does not have any associated immune reiection problems or costs.
MeSH term(s)	46, XX Disorders of Sex Development/complications ; Adult ; Allografts ; Amnion/transplantation ; Congenital Abnormalities/surgery ; Disorder of Sex Development, 46,XY/complications ; Female ; Gynecologic Surgical Procedures/methods ; Humans ; Vagina/abnormalities ; Vagina/surgery ; Young Adult
Language	English
Publishing date	2018-11-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	390916-5
ISSN	1943-3565 ; 0024-7758
ISSN (online)	1943-3565
ISSN	0024-7758
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Article: Clinical and ethical perspectives of medical professionals towards female genital cosmetic procedures

Yeğin, Gülin Feykan / Kılıç, Gökhan / İşlek Seçen, Elçin / Bahadır, İbrahim Buğra / Taş, Emre Erdem / Keskin, Hüseyin Levent / Yavuz, Ayşe Filiz

Turkish journal of obstetrics and gynecology

2021 Volume 18, Issue 2, Page(s) 131–138

Abstract: Objective: To evaluate the attitudes of medical students and professionals towards female genital cosmetic procedures (FGCPs) in terms of medical justification, applicability in practical life, ethical concerns, patient autonomy, and the clinical/social/ ...

Abstract	Objective: To evaluate the attitudes of medical students and professionals towards female genital cosmetic procedures (FGCPs) in terms of medical justification, applicability in practical life, ethical concerns, patient autonomy, and the clinical/social/psychological benefits-harms of these procedures. Materials and methods: A semi-structured questionnaire providing information about the attitudes of medical students and specialists (n=623) towards FGCPs including G-spot amplification, clitoral hood reduction, vaginoplasty, labia majora augmentation/reduction, labia minora augmentation/reduction, hymenoplasty, laser procedures, vulvar/perianal bleaching, and liposculpture, was completed by a target population and evaluated statistically. Results: Participants stated that FGCPs could be performed only upon patient request and there could rarely be a medical indication for their performance (p<0.05). Nearly half (44.5%) of the participants regarded hymenoplasty as controversial in terms of ethical issues, and 44.6% of participants do so for G-spot amplification. Over half (54.5%) of the participants agreed on the positive effect of FGCPs on improving the quality of life, 55.4% on improving self-esteem, and 54.1% on improving sexual functions of women. About half (49.3%) of respondents thought that the advertising and encouragement of FGCPs should be forbidden and 47% were indecisive about whether FGCPs constituted genital mutilation. Conclusion: The majority of the participants declared that FGCPs could be performed only upon patient request and improve self-esteem, quality of life, and sexual functions. The most controversial procedures in terms of ethics were hymenoplasty and G-spot amplification. Detailed guidelines for the protection of both patients and physicians are needed because the recommendations on FGCPs are insufficient to define the boundaries of medical justification, genital mutilation, advertising, and ethical concerns.
Language	English
Publishing date	2021-06-04
Publishing country	Turkey
Document type	Journal Article
ISSN	2149-9322
ISSN	2149-9322
DOI	10.4274/tjod.galenos.2021.85282
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Article ; Online: Low Anti-Mullerian Hormone Levels Are Associated with the Severity of Anxiety Experienced by Healthcare Professionals During the COVID-19 Pandemic.

Yeğin, Gülin Feykan / Desdicioğlu, Raziye / Seçen, Elcin İşlek / Aydın, Serap / Bal, Ceylan / Göka, Erol / Keskin, Huseyin Levent

Reproductive sciences (Thousand Oaks, Calif.)

2021 Volume 29, Issue 2, Page(s) 627–632

Abstract: The objective of this study is to investigate a possible correlation between anxiety status and anti-Mullerian hormone (AMH) levels among healthcare professionals who provide medical care directly to COVID-19-positive patients during the recent pandemic. ...

Abstract	The objective of this study is to investigate a possible correlation between anxiety status and anti-Mullerian hormone (AMH) levels among healthcare professionals who provide medical care directly to COVID-19-positive patients during the recent pandemic. Fifty-two healthcare professionals (nurses, midwives, and residents) who provide medical care directly to COVID-19-positive patients in inpatient clinics or intensive care units were enrolled in this study. Serum AMH levels were analyzed to reflect ovarian reserve. The Beck Anxiety Inventory (BAI) and the State-Trait Anxiety Inventory (STAI-S and STAI-T, respectively) were completed by participants to assess their anxiety status. A linear regression model with participant age as the constant variable was applied to analyze the relationship between inventory scale scores and AMH levels. P-values less than 0.05 were considered statistically significant. The mean AMH value was significantly lower for the participants in the moderate/severe anxiety group compared to the minimal/mild anxiety group (p = 0.007). A linear regression analysis revealed a significant negative correlation between AMH levels and both BAI (B = -0.030, standard error = 0.010, p = 0.004) and STAI-S and STAI-T scores when age was controlled (both p = 0.003). The severity of anxiety experienced during the recent COVID-19 pandemic among healthcare professionals, who provide medical care directly to COVID-19-positive patients, is found to be related to low AMH levels.
MeSH term(s)	Adult ; Anti-Mullerian Hormone/blood ; Anxiety/blood ; Anxiety/diagnosis ; Anxiety/psychology ; Biomarkers/blood ; COVID-19 ; Down-Regulation ; Female ; Humans ; Internship and Residency ; Midwifery ; Nursing Staff, Hospital ; Ovarian Reserve ; Predictive Value of Tests ; Risk Assessment ; Risk Factors ; Severity of Illness Index ; Young Adult
Chemical Substances	Biomarkers ; Anti-Mullerian Hormone (80497-65-0)
Language	English
Publishing date	2021-06-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2276411-2
ISSN	1933-7205 ; 1933-7191
ISSN (online)	1933-7205
ISSN	1933-7191
DOI	10.1007/s43032-021-00643-x
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Article ; Online: Diagnostic Evaluation of Pregnant Women Presentıng with Pruritis and Retrospective Analysis of Pregnancy Outcomes

Elçin Işlek Seçen / Raziye Desdicioglu / Gülin Feykan Yeğin / Ceylan Bal / A. Seval Erdinç / Dilek Uygur / Hüseyin Levent Keskin

Ankara Medical Journal, Vol 21, Iss 4, Pp 553-

2021 Volume 560

Abstract: INTRODUCTION: We aimed to evaluate the etiologic factors and pregnancy outcomes of pregnant women who applied to our antenatal outpatient clinics with the complaint of pruritus. METHODS: A retrospective study was conducted to examine the age, gestational ...

Abstract	INTRODUCTION: We aimed to evaluate the etiologic factors and pregnancy outcomes of pregnant women who applied to our antenatal outpatient clinics with the complaint of pruritus. METHODS: A retrospective study was conducted to examine the age, gestational weeks, gravidity, parity, comorbidities, laboratory test results and obstetric outcomes of pregnant women who applied with the complaint of pruritus to the antenatal follow-up outpatient clinics of Ankara City Hospital between 01.01.2020 and 31.12.2020. RESULTS: Medical records of 223 pregnant women who applied to our antenatal outpatient clinic with pruritus were evaluated, and the 181 pregnant with complete accessible data were enrolled in this study. The most common clinical diagnosis was pregnancy-specific dermatoses with a rate of 47.51% (n=86), and a specific diagnosis could not be determined in 80 pregnant women (44.19 %). Intrahepatic cholestasis (IHC) was found to be the most frequent diagnosis among the pregnancy-specific dermatoses with a percent of 25.41 (n=46). The incidence of IHC among specific dermatoses diagnosed ≥ 28 weeks of pregnancy was 30.76 %, and the most common dermatosis < 28 weeks was the atopic eruption of pregnancy (36.84 %). DISCUSSION AND CONCLUSION: Pruritus is a common condition in pregnancy; considering the frequency, especially in the third trimester, IHC should be kept in mind in the differential diagnosis to prevent maternal-fetal morbidity and mortality.
Keywords	pregnancy pruritus ; intrahepatic cholestasis ; pregnancy-specific dermatosis ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	610 ; 150
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	Ankara Yildirim Beyazit University
Document type	Article ; Online
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