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  1. Article ; Online: Incorrect P Values in Two Articles by Ke-Xuan Liu, M.D., Ph.D., et al.

    Liu, Ke-Xuan / Li, Cai / Yang, Wen-Han

    Anesthesiology

    2019  Volume 131, Issue 1, Page(s) 220

    MeSH term(s) Anesthetics ; Periodicals as Topic
    Chemical Substances Anesthetics
    Language English
    Publishing date 2019-06-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000002792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Study of the contents of Da He Wai Ke in the Ming Dynasty].

    Pu, Xiao-Lan / Zhang, Yi / Yang, Wen-Yu / Wu, Ya-Mei

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2012  Volume 42, Issue 1, Page(s) 30–37

    Abstract: Da He Wai Ke (the Great River External Medicine), an ancient book written by WANG Quan, a folk ... of the contents of this book showed that: (1) contents in volume 1 texts were mainly from Chuang Ke Tong Xuan Lun ... the disease names listed in Da He Wai Ke were basically consistent with the ones in an ancient Korean book ...

    Abstract Da He Wai Ke (the Great River External Medicine), an ancient book written by WANG Quan, a folk doctor, who was an apprentice of an unknown mysterious person in the Ming Dynasty. There are two volumes: thirty-six diseases were recorded in volume 1 with a figure for each disease before the descriptive texts, and 72 prescriptions were recorded in volume 2. The current research results about the origin of the contents of this book showed that: (1) contents in volume 1 texts were mainly from Chuang Ke Tong Xuan Lun (Enigmatic Theories for Sores Diseases); (2) there are no any direct clues about the source of the illustrations in volume 1. Though some of them are similar to those in Chuang Yang Jing Yan Quan Shu (the Collected Works for Experience in Sores (Diseases), it is impossible that the illustrations are from that book; (3) the disease names listed in Da He Wai Ke were basically consistent with the ones in an ancient Korean book entitled 36 Zhong Tu Lu (the 36 Illustrated Abscess Diseases); (4) the clues about where 67 of 72 prescriptions in volume 2 came from were revealed; (5) it was found that 27 of 37 prescriptions in the first half of volume 2 were rewritten from Chuang Ke Tong Xuan Lun, and 24 of them were completely corresponding to the prescriptions mentioned in volume 1; (6) 35 prescriptions in the second half of volume 2, showing no correlation with volume 1, were confirmed as subsequent supplements by Wang's descendants. Of the 35 prescriptions, 12 had close relationship to those in Chuang Yang Jing Yan Quan Shu : it is assumed that authors of the two books used the same books as their reference.
    Language Chinese
    Publishing date 2012-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Efficacy and indication optimization of Chinese medicine (Tiao-Chang Ke-Min granules) for diarrhea-predominant irritable bowel syndrome

    Qian Li / Bei-ping Zhang / Shao-gang Huang / Wen-wei Ouyang / Jian-hui Xie / Ze-huai Wen / Xiao-bo Yang

    Trials, Vol 19, Iss 1, Pp 1-

    study protocol for a randomized controlled trial

    2018  Volume 9

    Abstract: ... The aims of this study are to evaluate the efficacy and safety of Tiao-Chang Ke-Min (TCKM) granules for IBS ...

    Abstract Abstract Background Irritable bowel syndrome (IBS) is a chronic, recurring condition, prevalent in the general population. Current medication treatments usually leave patients undertreated. Nowadays, Chinese medicine (CM) is being considered as a promising treatment approach for IBS. However, due to methodological limitations, there is no strong evidence to support CM. Although IBS relapses are common, the relapse assessment has always been neglected in CM study designs. Meanwhile, in clinical practice and studies, it has been found that certain CM formulas can only benefit certain kinds of patients. Discovering what population and illness characteristics likely respond to outcomes may help improve the effectiveness of CM. The aims of this study are to evaluate the efficacy and safety of Tiao-Chang Ke-Min (TCKM) granules for IBS, especially in reducing IBS symptoms’ relapse, by a high-quality randomized controlled trial and then to optimize the indication of the TCKM granules. Methods/design This is a parallel-group, randomized, double-blind, placebo-controlled trial embedded with outcome predictive factors. Eligible patients with diarrhea-predominant IBS will be randomized into either a TCKM granule group or a placebo group. Patients from both groups will receive health education. The treatment duration is 4 weeks and the follow-up is 12 weeks. The primary outcome is global improvement measured with adequate relief (AR). The second outcome measures include time until relief, time until first relapse, total relapse times, long-term effectiveness, individual symptoms, IBS-Symptom Severity Score (IBS-SSS), IBS-Quality of Life Questionnaire (IBS-QOL), and Hospital Anxiety and Depression Scale (HADS). Predictive factors associated with patient and illness characteristics have been widely collected. These factors will be embedded in this trial for further identification. Discussion This trial may provide high-quality evidence on the efficacy and safety of TCKM granules for IBS and a more accurate indication. ...
    Keywords Irritable bowel syndrome ; Diarrhea-predominant ; Randomized controlled trial ; Prediction of the treatment outcome ; Indication ; Tiao-Chang Ke-Min granules ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2018-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Efficacy and indication optimization of Chinese medicine (Tiao-Chang Ke-Min granules) for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized controlled trial.

    Li, Qian / Zhang, Bei-Ping / Huang, Shao-Gang / Ouyang, Wen-Wei / Xie, Jian-Hui / Wen, Ze-Huai / Yang, Xiao-Bo

    Trials

    2018  Volume 19, Issue 1, Page(s) 367

    Abstract: ... The aims of this study are to evaluate the efficacy and safety of Tiao-Chang Ke-Min (TCKM) granules for IBS ...

    Abstract Background: Irritable bowel syndrome (IBS) is a chronic, recurring condition, prevalent in the general population. Current medication treatments usually leave patients undertreated. Nowadays, Chinese medicine (CM) is being considered as a promising treatment approach for IBS. However, due to methodological limitations, there is no strong evidence to support CM. Although IBS relapses are common, the relapse assessment has always been neglected in CM study designs. Meanwhile, in clinical practice and studies, it has been found that certain CM formulas can only benefit certain kinds of patients. Discovering what population and illness characteristics likely respond to outcomes may help improve the effectiveness of CM. The aims of this study are to evaluate the efficacy and safety of Tiao-Chang Ke-Min (TCKM) granules for IBS, especially in reducing IBS symptoms' relapse, by a high-quality randomized controlled trial and then to optimize the indication of the TCKM granules.
    Methods/design: This is a parallel-group, randomized, double-blind, placebo-controlled trial embedded with outcome predictive factors. Eligible patients with diarrhea-predominant IBS will be randomized into either a TCKM granule group or a placebo group. Patients from both groups will receive health education. The treatment duration is 4 weeks and the follow-up is 12 weeks. The primary outcome is global improvement measured with adequate relief (AR). The second outcome measures include time until relief, time until first relapse, total relapse times, long-term effectiveness, individual symptoms, IBS-Symptom Severity Score (IBS-SSS), IBS-Quality of Life Questionnaire (IBS-QOL), and Hospital Anxiety and Depression Scale (HADS). Predictive factors associated with patient and illness characteristics have been widely collected. These factors will be embedded in this trial for further identification.
    Discussion: This trial may provide high-quality evidence on the efficacy and safety of TCKM granules for IBS and a more accurate indication. Importantly, this trial will provide a new research method for improving the therapeutic effects of CM for clinicians and researchers. To address IBS relapse assessment, a series of special definitions of relapse incidents has been made for this trial.
    Trial registration: Chinese Clinical Trial Registry, ID: ChiCTR-IOR-17010600 . Registered on 9 February 2017.
    MeSH term(s) Adult ; Aged ; Diarrhea/drug therapy ; Double-Blind Method ; Female ; Humans ; Irritable Bowel Syndrome/drug therapy ; Irritable Bowel Syndrome/psychology ; Male ; Medicine, Chinese Traditional/adverse effects ; Middle Aged ; Outcome Assessment (Health Care) ; Quality Assurance, Health Care ; Quality of Life ; Randomized Controlled Trials as Topic ; Research Design ; Severity of Illness Index
    Language English
    Publishing date 2018-07-11
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1468-6708
    ISSN (online) 1745-6215 ; 1468-6694
    ISSN 1468-6708
    DOI 10.1186/s13063-018-2754-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Textual Research on Chiding Disease and Matixiang Herb in Da he wai ke (External Medicine of Da He)].

    Pu, Xiao-Lan / Zhang, Yi / Yang, Wen-Yu / Wu, Ya-Mei

    Zhonghua yi shi za zhi (Beijing, China : 1980)

    2012  Volume 42, Issue 6, Page(s) 346–354

    Abstract: Recorded in Da he wai ke (The External Medicine of Da He) in the Ming dynasty ... of Chiding, was regarded as a nonsuch drug by Da he wai ke, and was considered as a take-then-cure drug ...

    Abstract Recorded in Da he wai ke (The External Medicine of Da He) in the Ming dynasty without a corresponding disease title in contemporary scholarly concepts of Traditional Chinese Medicine (TCM), Chiding disease was described as an acute symptomatic disease with inevitable serious conditions of convulsion-like or mania-like behavior, and as a refractory ailment. It was also considered as an alias of Hongsiding (namely the acute lymphangitis) in few ancient books. Matixiang, a Chinese herb for treatment of Chiding, was regarded as a nonsuch drug by Da he wai ke, and was considered as a take-then-cure drug by Chuang yang jing yan quan shu (Compendium for Experience in Sores Diseases). The present studies about Chiding and Matixiang show that: (1) the name of Chiding was first seen in Zhong zang jing (Master Hua's Classic of the Viscera)

    (2) Chiding was rarely mentioned in medical literature of the Song, Yuan and Qing Dynasty, but mostly seen in the Ming Dynasty; (3) Xinding and Huoyanding were found as synonyms of Chiding

    (4) the distinction between Chiding and Hongsiding (flaming sore) was revealed by comparison analysis of their etiology, affected part(s), symptoms, prognosis and syndromic pictures; (5) Chiding on the tongue is the same as "Tongue Ding" or "Sublingual Ding" in contemporary TCM and as "Sublingual Space Infection" in Western Medicine. Moreover, Chiding on the hands, feet or other skin parts could be classified as "Hands/Feet Ding" in contemporary TCM and as "Furuncle" (i.e., Acute Suppurative Folliculitis and Perifolliculitis or cellulites of the tongue) in Western Medicine; (6) Matixiang is probably deduced as Asarum forbesii Maxim., A. ichangense C. Y. Cheng et C. S. Yang, family Aristolochiaceae, or Valeriana jatamansi Jones., family Valerianaceae.
    Language Chinese
    Publishing date 2012-11
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1052411-3
    ISSN 0255-7053
    ISSN 0255-7053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: In Vitro Hypoglycemic Activity of the Phenolic Compounds in Longan Fruit (Dimocarpus longan var. Fen Ke) Shell Against alpha-Glucosidase and beta-Galactosidase

    Li, Po-Hsien / Lin, Yu-Wen / Lu, Wen-Chien / Hu, Jyh-Ming / Huang, Da-Wei

    International journal of food properties

    2016  Volume 19, Issue 5/8, Page(s) 1786

    Document type Article
    ZDB-ID 1402715-x
    ISSN 1094-2912
    Database Current Contents Nutrition, Environment, Agriculture

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  7. Article: In Vitro Hypoglycemic Activity of the Phenolic Compounds in Longan Fruit (Dimocarpus longan var. Fen Ke) Shell Against α-Glucosidase and β-Galactosidase

    Li, Po-Hsien / Da-Wei Huang / Jyh-Ming Hu / Wen-Chien Lu / Yu-Wen Lin

    International journal of food properties. 2016 Aug. 2, v. 19, no. 8

    2016  

    Abstract: The in vitro hypoglycemic effect of longan fruit (Dimocarpus longan var. Fen Ke) shell extracts was ...

    Abstract The in vitro hypoglycemic effect of longan fruit (Dimocarpus longan var. Fen Ke) shell extracts was evaluated by inhibiting α-glucosidase and β-galactosidase activities. The IC ₅₀ values of hot water and 50% ethanol ultrasonic extracts against the α-glucosidase were 9.2 and 13.4 mg/mL, and those against the β-galactosidase were 12.9 and 19.7 mg/mL, respectively. The hot water extracts (20 mg/mL) with aid of ultrasound-assisted extraction may enhance the inhibitory rates of α-glucosidase and β-galactosidase by 10.6 and 12.0% as compared with conventional extraction, respectively. Two phenolic compounds, gallic acid and ellagic acid, were identified as the major phenolic in hot water extracts from longan fruit shell against α-glucosidase and β-galactosidase. Inhibition of α-glucosidase and β-galactosidase were proven to be as a therapeutic approach for decreasing postprandial hyperglycemia. As a result, the longan fruit shell extracts may develop to be as a potential strategy for early treatment of postprandial hyperglycemia.
    Keywords alpha-glucosidase ; beta-galactosidase ; Dimocarpus longan ; ellagic acid ; ethanol ; gallic acid ; glycemic effect ; hyperglycemia ; inhibitory concentration 50 ; longans ; ultrasonic treatment ; ultrasonics
    Language English
    Dates of publication 2016-0802
    Size p. 1786-1797.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 1402715-x
    ISSN 1532-2386 ; 1094-2912
    ISSN (online) 1532-2386
    ISSN 1094-2912
    DOI 10.1080/10942912.2015.1085398
    Database NAL-Catalogue (AGRICOLA)

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  8. Book: Tong yong zhong wen ke ben

    Shen, Wen / Yang, Shiquan

    = Chinese Reader

    2001  

    Author's details Shen Wen, Yang Shiquan
    Language Chinese ; English
    Size 54 S.
    Publisher Beijing yu yan da xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787561909874 ; 756190987X
    Database Former special subject collection: coastal and deep sea fishing

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  9. Book: Tong yong zhong wen ke ben

    Shen, Wen / Yang, Shiquan

    = Chinese Reader

    2001  

    Author's details Shen Wen, Yang Shiquan
    Language Chinese ; English
    Size 44 S.
    Publisher Beijing yu yan da xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787561909867 ; 7561909861
    Database Former special subject collection: coastal and deep sea fishing

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  10. Book: Tong yong zhong wen ke ben

    Shen, Wen / Yang, Shiquan

    = Chinese Reader

    2001  

    Author's details Shen Wen, Yang Shiquan
    Language Chinese ; English
    Size 45 S.
    Publisher Beijing yu yan da xue chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 9787561909898 ; 7561909896
    Database Former special subject collection: coastal and deep sea fishing

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