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  1. Article: Increased Recognition of Non-O157 Shiga Toxin-Producing Escherichia coli Infections in the United States During 2000-2010: Epidemiologic Features and Comparison with E. coli O157 Infections. L. H. Gould, R. K. Mody, K. L. Ong, P. Clogher, A. B. Cronquist, K. N. Garman, S. Lathrop, C. Medus, N. L. Spina, T. H. Webb, P. L. White, K. Wymore, R. E. Gierke, B. E. Mahon, and P. M. Griffin, for the Emerging Infections Program Foodnet Working Group

    Gould, L. H. / Mody, R. K. / Ong, K. L. / Clogher, P. / Cronquist, A. B. / Garman, K. N. / Lathrop, S. / Medus, C. / Spina, N. L. / Webb, T. H. / White, P. L. / Wymore, K. / Gierke, R. E. / Mahon, B. E. / Griffin, P. M.

    Foodborne pathogens and disease

    2013  Volume 10, Issue 5, Page(s) 453

    Language English
    Document type Article
    ZDB-ID 2148479-X
    ISSN 1535-3141
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 7517: Show issues

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  2. Book ; Online: The Living Stream

    Gould, Warwick

    2013  

    Abstract: ... Chapman, Sandra Clark, Denis Donoghue, Nicholas Grene, Joseph M. Hassett, and K.P.S. Jochum.Yeats Annual ... Neil Corcoran, Warwick Gould, Joseph M. Hassett, Phillip L. Marcus, Ann Saddlemyer, Ronald Schuchard ... Matthew de Forrest, while reviews of recent editions and studies are provided by Matthew Campbell, Wayne K ...

    Abstract Yeats Annual No. 18 is another special issue in this renowned research-level series offering a tribute to the pioneering Yeats scholar, A. Norman Jeffares. Memories of the man are shared by Seamus Heaney, Christopher Rush and Colin Smythe, who compiles a bibliography of Jeffares's work. Terence Brown, Neil Corcoran, Warwick Gould, Joseph M. Hassett, Phillip L. Marcus, Ann Saddlemyer, Ronald Schuchard, Deirdre Toomey and Helen Vendler offer essays on such topics as Yeats and the Colours of Poetry, Yeats's Shakespeare, Yeats and Seamus Heaney, Lacrimae Rerum and Tragic Joy, Raftery's work on Yeats's Thoor Ballylee, Edmund Dulac's portrait of Mrs George Yeats, The Tower as an anti-Modernist monument, with close studies of 'Vacillation', 'Her Triumph', and 'The Cold Heaven'. Throughout, the essays are inflected with memories of Jeffares and his critical methods. The volume is rounded with further essays on A Vision by Neil Mann and Matthew de Forrest, while reviews of recent editions and studies are provided by Matthew Campbell, Wayne K. Chapman, Sandra Clark, Denis Donoghue, Nicholas Grene, Joseph M. Hassett, and K.P.S. Jochum.Yeats Annual is published by Open Book Publishers in association with the Institute of English Studies, University of London
    Keywords Literature (General)
    Size 1 electronic resource (396 p.)
    Publisher Open Book Publishers
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020098170
    ISBN 9781909254374 ; 1909254371
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Experimental studies with Staphylococcus aureus in M-K media.

    Brightbill, F S / Terrones, C / Gould, S

    Investigative ophthalmology

    1976  Volume 15, Issue 1, Page(s) 32–34

    Abstract: ... obtained on all eyes before and after application of the antibiotic. Corneas were stored in M-K media ...

    Abstract This study reviewed the potential for survival of a pathogenic bacteria when inoculated into McCarey-Kaufman modified tissue culture media 199. A clinically isolated specimen of Staphylococcus aureus was selected and rabbit eyes inoculated with 0.1 ml. of the organism in a suspension of 1 to 3 x 10(-5). Upon enucleation 12 hours later no clinical signs of infection were noted. Limbal-conjunctival cultures were obtained on all eyes before and after application of the antibiotic. Corneas were stored in M-K media with standard penicillin-streptomycin added and cultured up to 48 hours. Our studies showed some recovery of the infecting organism from the media with topical antibiotic application but none following complete immersion of eyes in antibiotic. Direct cultures from corneal buttons taken 48 to 72 hours after antibiotic application by either method showed 1 to 3 colonies per plate in 25 per cent of eyes. In this study improperly applied antibiotic allowed some survival of S. aureus in the media.
    MeSH term(s) Animals ; Cornea/microbiology ; Culture Media ; Neomycin/administration & dosage ; Neomycin/pharmacology ; Polymyxins/administration & dosage ; Polymyxins/pharmacology ; Rabbits ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/growth & development ; Tissue Preservation
    Chemical Substances Culture Media ; Polymyxins ; Neomycin (1404-04-2)
    Language English
    Publishing date 1976-01
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 80344-3
    ISSN 0020-9988
    ISSN 0020-9988
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 45: Show issues Location:
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  4. Book: Fischer's Mastery of Surgery. (2 Vol Sets)

    Ellison, E. Christopher / Galandiuk, Susan / Pawlik, Timothy M. / Chapman, William C. / Poulose, Benjamin Kuttikatt / Henke, Peter K. / Mohr, Alicia / Islam, Mirza Saleem / Agur, Anne M. R. / Scott-Conner, Carol E. H. / Renton, David / Upchurch, Gilbert R. / Efron, Philip Alexander / Wexner, Steven D. / Perrier, Nancy D. / Klimberg, V. Suzanne / Stewart, John H. / Rusch, Valerie W. / Gould, Jon C.

    (Biopsy Interpretation Series)

    2023  

    Series title Biopsy Interpretation Series
    Keywords Surgery ; Surgical textbook ; General surgery reference ; Surgical techniques ; Surgical procedures ; Surgical education ; Surgical training ; Surgical skills ; Surgical knowledge ; Surgical practice ; Surgical principles ; Surgical specialties ; Surgical subspecialties ; Operative procedures ; Surgical cases ; Surgical guidelines ; Surgical best practices ; Surgical reviews ; Surgical updates ; Surgical board exams
    Language English
    Size 2810 p.
    Edition 8
    Publisher Lippincott Williams
    Document type Book
    Note PDA Manuell_24
    Format 237 x 301 x 147
    ISBN 9781975176433 ; 197517643X
    Database PDA

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  5. Article: The fission yeast cytokinetic ring component Fic1 promotes septum formation.

    Rossi, Anthony M / Bohnert, K Adam / Gould, Kathleen L

    bioRxiv : the preprint server for biology

    2023  

    Abstract: In : Summary statement: ... ...

    Abstract In
    Summary statement: The
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.03.13.532462
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The fission yeast cytokinetic ring component Fic1 promotes septum formation.

    Rossi, Anthony M / Bohnert, K Adam / Gould, Kathleen L

    Biology open

    2023  Volume 12, Issue 5

    Abstract: In Schizosaccharomyces pombe, septum formation is coordinated with cytokinetic ring constriction but the mechanisms linking these events are unclear. In this study, we explored the role of the cytokinetic ring component Fic1, first identified by its ... ...

    Abstract In Schizosaccharomyces pombe, septum formation is coordinated with cytokinetic ring constriction but the mechanisms linking these events are unclear. In this study, we explored the role of the cytokinetic ring component Fic1, first identified by its interaction with the F-BAR protein Cdc15, in septum formation. We found that the fic1 phospho-ablating mutant, fic1-2A, is a gain-of-function allele that suppresses myo2-E1, the temperature-sensitive allele of the essential type-II myosin, myo2. This suppression is achieved by the promotion of septum formation and required Fic1's interaction with the F-BAR proteins Cdc15 and Imp2. Additionally, we found that Fic1 interacts with Cyk3 and that this interaction was likewise required for Fic1's role in septum formation. Fic1, Cdc15, Imp2, and Cyk3 are the orthologs of the Saccharomyces cerevisiae ingression progression complex, which stimulates the chitin synthase Chs2 to promote primary septum formation. However, our findings indicate that Fic1 promotes septum formation and cell abscission independently of the S. pombe Chs2 ortholog. Thus, while similar complexes exist in the two yeasts that each promote septation, they appear to have different downstream effectors.
    MeSH term(s) Schizosaccharomyces/genetics ; Schizosaccharomyces/metabolism ; Schizosaccharomyces pombe Proteins/genetics ; Schizosaccharomyces pombe Proteins/metabolism ; Cell Cycle Proteins/metabolism ; Cytokinesis ; Saccharomyces cerevisiae/metabolism ; Cytoskeletal Proteins/metabolism ; Myosin Heavy Chains/metabolism ; Myosin Type II/metabolism
    Chemical Substances Schizosaccharomyces pombe Proteins ; Cell Cycle Proteins ; IMP2 protein, S pombe ; Cytoskeletal Proteins ; MYO2 protein, S pombe ; Myosin Heavy Chains (EC 3.6.4.1) ; Myosin Type II (EC 3.6.1.-)
    Language English
    Publishing date 2023-05-09
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2632264-X
    ISSN 2046-6390 ; 2046-6390
    ISSN (online) 2046-6390
    ISSN 2046-6390
    DOI 10.1242/bio.059957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Chlorhexidine Resistance or Cross-Resistance, That Is the Question.

    Abbood, Hadeel Mohammed / Hijazi, Karolin / Gould, Ian M

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: Chlorohexidine (CHX) is a widely used biocide in clinical and household settings. Studies over the last few decades have reported CHX resistance in different bacterial species, but at concentrations well below those used in the clinical setting. ... ...

    Abstract Chlorohexidine (CHX) is a widely used biocide in clinical and household settings. Studies over the last few decades have reported CHX resistance in different bacterial species, but at concentrations well below those used in the clinical setting. Synthesis of these findings is hampered by the inconsistent compliance with standard laboratory procedures for biocide susceptibility testing. Meanwhile, studies of in vitro CHX-adapted bacteria have reported cross-resistance between CHX and other antimicrobials. This could be related to common resistance mechanisms of CHX and other antimicrobials and/or the selective pressure driven by the intensive use of CHX. Importantly, CHX resistance and cross-resistance to antimicrobials should be investigated in clinical as well as environmental isolates to further our understanding of the role of CHX in selection of multidrug resistance. Whilst clinical studies to support the hypothesis of CHX cross-resistance with antibiotics are currently lacking, we recommend raising the awareness of healthcare providers in a range of clinical disciplines regarding the potential adverse impact of the unfettered use of CHX on tackling antimicrobial resistance.
    Language English
    Publishing date 2023-04-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12050798
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The fission yeast cytokinetic ring component Fic1 promotes septum formation

    Anthony M. Rossi / K. Adam Bohnert / Kathleen L. Gould

    Biology Open, Vol 12, Iss

    2023  Volume 5

    Keywords fission yeast ; cytokinetic ring ; cytokinesis ; septation ; myosin ii ; Science ; Q ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher The Company of Biologists
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  9. Article ; Online: An online intervention for carers to manage behavioral symptoms in motor neuron disease (MiNDToolkit): a randomized parallel multi-center feasibility trial.

    Mioshi, E / Grant, K / Flanagan, E / Heal, S / Copsey, H / Gould, R L / Hammond, M / Shepstone, L / Ashford, P A

    Amyotrophic lateral sclerosis & frontotemporal degeneration

    2024  , Page(s) 1–11

    Abstract: Background: Evidence on management of behavioral symptoms in motor neuron disease (MND) is lacking. The MiNDToolkit, an online psychoeducational platform, supports carers dealing with behavioral symptoms (BehSymp). The study objectives were to ascertain ...

    Abstract Background: Evidence on management of behavioral symptoms in motor neuron disease (MND) is lacking. The MiNDToolkit, an online psychoeducational platform, supports carers dealing with behavioral symptoms (BehSymp). The study objectives were to ascertain recruitment and retention rates, carer and healthcare professional (HCP) use of the platform, and completion of online assessments, to inform a full-scale trial.
    Setting: England and Wales, across diverse MND services; recruitment from July/21 to November/22; last participant follow-up in March/23.
    Participants: Carers of people with motor neuron disease (PwMND) with BehSymp, recruited through MND services. After confirming eligibility, participants completed screening and baseline assessments online via the MiNDToolkit platform and were randomized centrally in a 1:1 ratio to MiNDToolkit or control.
    Intervention: MiNDToolkit offered tailored modules to carers for the 3-month study period. Carers in the intervention group could receive additional support from MiNDToolkit trained HCPs. The control group was offered access to the intervention at the end of the study. Data were collected on platform usage and psychosocial variables.
    Main outcomes: One hundred and fifty-one carers from 11 sites were invited to join the study (letter, face-to-face); 30 were screened; 29 were randomized. Fifteen people were allocated to the control arm; 14 to intervention. Carers were mostly female; median age for was 62.5 (IQR: 58, 68; intervention) and 57 (IQR: 56, 70; controls). Study retention was high (24/29 = 82.76%); carers engaged with the platform on average 14 times (median (IQR):14.0 (10.0, 18.5)) during the study period.
    Conclusion: The MiNDToolkit study was feasible and well accepted by carers and trained HCPs. A definitive trial is warranted.
    Language English
    Publishing date 2024-05-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2705049-X
    ISSN 2167-9223 ; 2167-8421
    ISSN (online) 2167-9223
    ISSN 2167-8421
    DOI 10.1080/21678421.2024.2350658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5874: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Selective M

    Teal, Laura B / Bubser, Michael / Duncan, Edith / Gould, Robert W / Lindsley, Craig W / Jones, Carrie K

    Neuropharmacology

    2023  Volume 227, Page(s) 109424

    Abstract: Recent evidence suggests that inhibition of the M ...

    Abstract Recent evidence suggests that inhibition of the M
    MeSH term(s) Animals ; Male ; Rats ; Analgesics, Opioid ; Opioid-Related Disorders ; Oxycodone ; Rats, Sprague-Dawley ; Receptors, Muscarinic ; Self Administration ; Sucrose/pharmacology
    Chemical Substances Analgesics, Opioid ; Oxycodone (CD35PMG570) ; Receptors, Muscarinic ; Sucrose (57-50-1) ; VU6008667
    Language English
    Publishing date 2023-01-28
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 218272-5
    ISSN 1873-7064 ; 0028-3908
    ISSN (online) 1873-7064
    ISSN 0028-3908
    DOI 10.1016/j.neuropharm.2023.109424
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    Ui I Zs.242: Show issues Location:
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