Article ; Online: Low mortality from COVID-19 at a nursing facility in France following a combined preventive and active treatment protocol.
2021 Volume 10, Issue 11, Page(s) 11288–11300
Abstract: Background: The aim of this study was to retrospectively describe the evolution of symptoms, infections, and mortality at a nursing facility in France that had implemented a protocol for the prevention and treatment of COVID-19.: Methods: A database ... ...
| Abstract | Background: The aim of this study was to retrospectively describe the evolution of symptoms, infections, and mortality at a nursing facility in France that had implemented a protocol for the prevention and treatment of COVID-19. Methods: A database was created on 21 March 2020 to store all information related to residents, including co-morbidities, as well as COVID-19 symptoms, incidence, and mortality. Residents followed a COVID-19 protocol, consisting of preventive (administering vitamins and zinc, social distancing, and temperature checks) and active (antibiotics, anticoagulants, and corticosteroids) measures. RT-PCR and serology testing were performed on residents. A new coefficient, named the Zemgor coefficient, was calculated as the haemoglobin-to-albumin ratio at 2 time points 15 days apart, to monitor hypoxemia. Results: In January 2020, the nursing facility housed 192 residents, 75 men and 117 women, aged 80±11. One or more co-morbidities were present in 94% of residents, with the most common being dementia. The COVID-19 protocol provided 61% of residents with anticoagulants, 51%with antibiotics, 21% with oxygen therapy, and 3% with corticosteroids. The COVID-19 incidence was 51% based on presence of COVID-19 symptoms, 35% based on positive RT-PCR (amongst residents tested for RT-PCR) and 41% based on positive serology (amongst residents tested for serology), and the COVID-19 mortality rate was 8%. The Zemgor coefficient was 0.049±0.053 for patients with hypoxemia compared to 0.011±0.041 for patients without hypoxemia (P=0.001). Conclusions: The protocol for the prevention and treatment of COVID-19 implemented at this nursing facility resulted in a COVID-19 incidence and mortality at the lower end of that reported by other nursing facilities. |
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| MeSH term(s) | COVID-19 ; Clinical Protocols ; Female ; France ; Humans ; Male ; Retrospective Studies ; SARS-CoV-2 |
| Language | English |
| Publishing date | 2021-10-12 |
| Publishing country | China |
| Document type | Journal Article |
| ZDB-ID | 2828544-X |
| ISSN | 2224-5839 ; 2224-5839 |
| ISSN (online) | 2224-5839 |
| ISSN | 2224-5839 |
| DOI | 10.21037/apm-21-1707 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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