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Article ; Online: A Dynamic Endonasal Columellar Strut Placement.

Sanchez-Perez, Jose R / Del Toro-Diez, Edgar F / Abdul-Hadi, Soraya / Aldrich-Novoa, Jorge

2023 Volume 134, Issue 3, Page(s) 1246–1248

Abstract: The dynamic retrograde intercrural columellar strut graft placement is a novel technique for a columellar strut insertion via a hemi-transfixion incision in patients undergoing endonasal functional or cosmetic surgery. It has a maximally concealed ... ...

Abstract	The dynamic retrograde intercrural columellar strut graft placement is a novel technique for a columellar strut insertion via a hemi-transfixion incision in patients undergoing endonasal functional or cosmetic surgery. It has a maximally concealed incision and does not disrupt major or minor tip support mechanisms. In our article, we give a detailed description of this unique surgical technique. Laryngoscope, 134:1246-1248, 2024.
MeSH term(s)	Humans ; Rhinoplasty/methods ; Nose/surgery ; Nasal Septum/surgery ; Prostheses and Implants ; Esthetics ; Suture Techniques ; Treatment Outcome
Language	English
Publishing date	2023-07-14
Publishing country	United States
Document type	Case Reports
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.30897
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Article ; Online: Equivalent impacts of logging and beaver activities on aboveground carbon stock loss in the southernmost forest on Earth.

Miranda, Alejandro / Hoyos-Santillan, Jorge / Lara, Antonio / Mentler, Rayén / Huertas-Herrera, Alejandro / Toro-Manríquez, Mónica D R / Sepulveda-Jauregui, Armando

Scientific reports

2023 Volume 13, Issue 1, Page(s) 18350

Abstract: The conservation of forest landscapes is crucial for global climate strategies, and the forest in Tierra del Fuego, located in Patagonia, represents the southernmost example on Earth. These ecosystems are critical for Chile's roadmap toward carbon ... ...

Abstract	The conservation of forest landscapes is crucial for global climate strategies, and the forest in Tierra del Fuego, located in Patagonia, represents the southernmost example on Earth. These ecosystems are critical for Chile's roadmap toward carbon neutrality. Unfortunately, these ecosystems have been impacted by logging and beaver activities. Currently, the precise contribution of each driver to forest cover and carbon stock loss remains insufficiently quantified, impeding effective policymaking and the implementation of strategies to safeguard and enhance carbon stocks in these ecosystems. In this study, we conducted an assessment of forest carbon stock loss resulting from both logging and beaver activities in Chilean Tierra del Fuego from 1986 to 2019. While beavers have received significant attention for their substantial contribution to forest cover loss (56.1% forest cover, ≈ 1.4 MtC), our findings suggest that logging has nearly equally contributed to carbon stock depletion (43.8% forest cover, ≈ 1.2 MtC). Consequently, the prevailing focus on beavers has obscured the ongoing logging-induced carbon stock loss. The implications of our study highlight the urgency for comprehensive consideration of both drivers in Chile's climate strategy to fulfill the country's mitigation commitments.
MeSH term(s)	Animals ; Ecosystem ; Trees ; Carbon ; Rodentia ; Tropical Climate ; Forests
Chemical Substances	Carbon (7440-44-0)
Language	English
Publishing date	2023-10-26
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-45657-4
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Article ; Online: Equivalent impacts of logging and beaver activities on aboveground carbon stock loss in the southernmost forest on Earth

Alejandro Miranda / Jorge Hoyos-Santillan / Antonio Lara / Rayén Mentler / Alejandro Huertas-Herrera / Mónica D. R. Toro-Manríquez / Armando Sepulveda-Jauregui

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 9

Abstract: Abstract The conservation of forest landscapes is crucial for global climate strategies, and the forest in Tierra del Fuego, located in Patagonia, represents the southernmost example on Earth. These ecosystems are critical for Chile’s roadmap toward ... ...

Abstract	Abstract The conservation of forest landscapes is crucial for global climate strategies, and the forest in Tierra del Fuego, located in Patagonia, represents the southernmost example on Earth. These ecosystems are critical for Chile’s roadmap toward carbon neutrality. Unfortunately, these ecosystems have been impacted by logging and beaver activities. Currently, the precise contribution of each driver to forest cover and carbon stock loss remains insufficiently quantified, impeding effective policymaking and the implementation of strategies to safeguard and enhance carbon stocks in these ecosystems. In this study, we conducted an assessment of forest carbon stock loss resulting from both logging and beaver activities in Chilean Tierra del Fuego from 1986 to 2019. While beavers have received significant attention for their substantial contribution to forest cover loss (56.1% forest cover, ≈ 1.4 MtC), our findings suggest that logging has nearly equally contributed to carbon stock depletion (43.8% forest cover, ≈ 1.2 MtC). Consequently, the prevailing focus on beavers has obscured the ongoing logging-induced carbon stock loss. The implications of our study highlight the urgency for comprehensive consideration of both drivers in Chile’s climate strategy to fulfill the country’s mitigation commitments.
Keywords	Medicine ; R ; Science ; Q
Subject code	333
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
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Article ; Online: Molecular Dynamics Study of the Conformation, Ion Adsorption, Diffusion, and Water Structure of Soluble Polymers in Saline Solutions.

Quezada, Gonzalo R / Toro, Norman / Saavedra, Jorge / Robles, Pedro / Salazar, Iván / Navarra, Alessandro / Jeldres, Ricardo I

Polymers

2021 Volume 13, Issue 20

Abstract: Polymers have interesting physicochemical characteristics such as charge density, functionalities, and molecular weight. Such attributes are of great importance for use in industrial purposes. Understanding how these characteristics are affected is still ...

Abstract	Polymers have interesting physicochemical characteristics such as charge density, functionalities, and molecular weight. Such attributes are of great importance for use in industrial purposes. Understanding how these characteristics are affected is still complex, but with the help of molecular dynamics (MD) and quantum calculations (QM), it is possible to understand the behavior of polymers at the molecular level with great consistency. This study was applied to polymers derived from polyacrylamide (PAM) due to its great use in various industries. The polymers studied include hydrolyzed polyacrylamide (HPAM), poly (2-acrylamido-2-methylpropanesulfonate) (PAMPS), polyacrylic acid (PAA), polyethylene oxide polymer (PEO), and guar gum polysaccharide (GUAR). Each one has different attributes, which help in understanding the effects on the polymer and the medium in which it is applied along a broad spectrum. The results include the conformation, diffusion, ion condensation, the structure of the water around the polymer, and interatomic polymer interactions. Such characteristics are important to selecting a polymer depending on the environment in which it is found and its purpose. The effect caused by salinity is particular to each polymer, where polymers with an explicit charge or polyelectrolytes are more susceptible to changes due to salinity, increasing their coiling and reducing their mobility in solution. This naturally reduces its ability to form polymeric bridges due to having a polymer with a smaller gyration radius. In contrast, neutral polymers are less affected in their structure, making them favorable in media with high ionic charges.
Language	English
Publishing date	2021-10-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym13203550
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Article ; Online: Molecular Dynamics Study of the Conformation, Ion Adsorption, Diffusion, and Water Structure of Soluble Polymers in Saline Solutions

Gonzalo R. Quezada / Norman Toro / Jorge Saavedra / Pedro Robles / Iván Salazar / Alessandro Navarra / Ricardo I. Jeldres

Polymers, Vol 13, Iss 3550, p

2021 Volume 3550

Abstract	Polymers have interesting physicochemical characteristics such as charge density, functionalities, and molecular weight. Such attributes are of great importance for use in industrial purposes. Understanding how these characteristics are affected is still complex, but with the help of molecular dynamics (MD) and quantum calculations (QM), it is possible to understand the behavior of polymers at the molecular level with great consistency. This study was applied to polymers derived from polyacrylamide (PAM) due to its great use in various industries. The polymers studied include hydrolyzed polyacrylamide (HPAM), poly (2-acrylamido-2-methylpropanesulfonate) (PAMPS), polyacrylic acid (PAA), polyethylene oxide polymer (PEO), and guar gum polysaccharide (GUAR). Each one has different attributes, which help in understanding the effects on the polymer and the medium in which it is applied along a broad spectrum. The results include the conformation, diffusion, ion condensation, the structure of the water around the polymer, and interatomic polymer interactions. Such characteristics are important to selecting a polymer depending on the environment in which it is found and its purpose. The effect caused by salinity is particular to each polymer, where polymers with an explicit charge or polyelectrolytes are more susceptible to changes due to salinity, increasing their coiling and reducing their mobility in solution. This naturally reduces its ability to form polymeric bridges due to having a polymer with a smaller gyration radius. In contrast, neutral polymers are less affected in their structure, making them favorable in media with high ionic charges.
Keywords	soluble polymers ; flocculation ; salinity ; molecular dynamic ; ion adsorption ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Early-life external exposome in children 2-5 years old in Colombia.

Marín, Diana / Basagaña, Xavier / Amaya, Ferney / Aristizábal, Luis Miguel / Muñoz, Diego Alejandro / Domínguez, Alan / Molina, Francisco / Ramos, Carlos Daniel / Morales-Betancourt, Ricardo / Hincapié, Roberto / Rodríguez-Villamizar, Laura / Rojas, Yurley / Morales, Olga / Cuellar, Martha / Corredor, Andrea / Villamil-Osorio, Milena / Bejarano, María Alejandra / Vidal, Dolly / Narváez, Diana M /

Groot, Helena / Builes, Juan José / López, Lucelly / Henao, Enrique Antonio / Lopera, Verónica / Hernández, Luis Jorge / Bangdiwala, Shrikant I / Marín-Ochoa, Beatriz / Oviedo, Ana Isabel / Sánchez-García, Oscar Eduardo / Toro, María Victoria / Riaño, Will / Rueda, Zulma Vanessa

Environmental research

2024 Volume 252, Issue Pt 3, Page(s) 118913

Abstract: ... within exposure groups were observed in meteorology (r = 0.85), traffic (r = 0.83), and atmospheric pollutants (r ... such as atmospheric pollutants and meteorology (r = 0.76), natural spaces (r = -0.34), and the built environment (r = 0.53 ...

Abstract	Exposome studies are advancing in high-income countries to understand how multiple environmental exposures impact health. However, there is a significant research gap in low- and middle-income and tropical countries. We aimed to describe the spatiotemporal variation of the external exposome, its correlation structure between and within exposure groups, and its dimensionality. A one-year follow-up cohort study of 506 children under 5 in two cities in Colombia was conducted to evaluate asthma, acute respiratory infections, and DNA damage. We examined 48 environmental exposures during pregnancy and 168 during childhood in eight exposure groups, including atmospheric pollutants, natural spaces, meteorology, built environment, traffic, indoor exposure, and socioeconomic capital. The exposome was estimated using geographic information systems, remote sensing, spatiotemporal modeling, and questionnaires. The median age of children at study entry was 3.7 years (interquartile range: 2.9-4.3). Air pollution and natural spaces exposure decreased from pregnancy to childhood, while socioeconomic capital increased. The highest median correlations within exposure groups were observed in meteorology (r = 0.85), traffic (r = 0.83), and atmospheric pollutants (r = 0.64). Important correlations between variables from different exposure groups were found, such as atmospheric pollutants and meteorology (r = 0.76), natural spaces (r = -0.34), and the built environment (r = 0.53). Twenty principal components explained 70%, and 57 explained 95% of the total variance in the childhood exposome. Our findings show that there is an important spatiotemporal variation in the exposome of children under 5. This is the first characterization of the external exposome in urban areas of Latin America and highlights its complexity, but also the need to better characterize and understand the exposome in order to optimize its analysis and applications in local interventions aimed at improving the health conditions and well-being of the child population and contributing to environmental health decision-making.
Language	English
Publishing date	2024-04-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2024.118913
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Article: Prevalence of Anti-SARS-CoV-2 Antibodies and Associated Factors Among Health Care Workers in Santiago De Cali, Colombia.

Osorio-Toro, Luis Miguel / Bonilla-Bonilla, Diana Marcela / Daza-Arana, Jorge Enrique / Aristizábal, Juan Carlos / Ávila-Valencia, Juan Carlos / Ramírez-Marmolejo, Roberto

International journal of general medicine

2023 Volume 16, Page(s) 697–705

Abstract: Purpose: This study aims to determine the seroprevalence of coronavirus disease (COVID-19) among health care workers and describe the associated sociodemographic and labor features.: Patients and methods: An observational study with an analytical ... ...

Abstract	Purpose: This study aims to determine the seroprevalence of coronavirus disease (COVID-19) among health care workers and describe the associated sociodemographic and labor features. Patients and methods: An observational study with an analytical component was conducted at a clinic in Cali, Colombia. The sample size was 708 health workers and they were selected by stratified random sampling. A Bayesian analysis was developed to determine the raw and adjusted prevalence. A Poisson regression model was used to estimate the prevalence ratios. Results: Overall seroprevalence of COVID-19 among healthcare workers was 29%. Miscellaneous services workers, healthcare, and administrative workers, was 38%, 33%, and 32%, respectively. Factors related to seropositivity were having a contact with a COVID-19 patient for >120 minutes and being diagnosed with COVID-19 by laboratory tests. Conclusion: The present study shows a adjusted seroprevalence of 29% in health workers, indicating a high level of disease transmission and an increased risk of infection in this population group.
Language	English
Publishing date	2023-02-23
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2452220-X
ISSN	1178-7074
ISSN	1178-7074
DOI	10.2147/IJGM.S396357
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Article ; Online: Nasal Provocation Challenges with Aedes aegypti Whole-Body Extract Induces Allergic Rhinitis.

Sánchez, Jorge / Toro, Yuliana / Cantillo, José-Fernando / Martínez, Dalgys / Fernández-Caldas, Enrique / Cardona, Ricardo / Puerta, Leonardo

International archives of allergy and immunology

2023 Volume 184, Issue 4, Page(s) 366–369

Abstract: Background: Exposure to mosquitoes in the Tropics is perennial, and their somatic and saliva antigens have shown IgE binding capacity, although it is not clear whether this is due to cross-reactivity or primary sensitization. Inhalation of these ... ...

Abstract	Background: Exposure to mosquitoes in the Tropics is perennial, and their somatic and saliva antigens have shown IgE binding capacity, although it is not clear whether this is due to cross-reactivity or primary sensitization. Inhalation of these allergens could trigger an allergic response. Objective: The aim of the study was to evaluate the clinical relevance of sensitization to Aedes aegypti in a group of patients with allergic rhinitis. Methods: A cross-sectional study with allergic rhinitis subjects and healthy controls sensitized to mosquito extract was performed. Sensitization to mosquito and house dust mites was evaluated using skin prick test (SPT) and antibody determination by ELISA. Nasal provocation test (NPT) with whole-body extract was used to determine clinical relevance. Results: Allergic rhinitis patients were more sensitized to mosquito extract than controls with (+) SPT (66.6% vs. 7.6%). From these (+) SPT patients, 44.5% had (+) NPT, and just two (11%) presented mono-sensitization to mosquito. Antibody reactivity was similar between patients and controls; however, (+) NPT patients showed a tendency to had higher levels of IgE and IgG4. Discussion: Mosquitoes are perennial in most tropical areas, and their body allergens could be associated with respiratory allergies.
MeSH term(s)	Animals ; Humans ; Aedes ; Cross-Sectional Studies ; Rhinitis, Allergic/diagnosis ; Allergens ; Nasal Provocation Tests ; Skin Tests ; Immunoglobulin E ; Plant Extracts
Chemical Substances	Allergens ; Immunoglobulin E (37341-29-0) ; Plant Extracts
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1108932-5
ISSN	1423-0097 ; 1018-2438
ISSN (online)	1423-0097
ISSN	1018-2438
DOI	10.1159/000528196
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Article: The Effects of Vitamin C on the Multiple Pathophysiological Stages of COVID-19.

Miranda-Massari, Jorge R / Toro, Alondra P / Loh, Doris / Rodriguez, Jose R / Borges, Raul Morales / Marcial-Vega, Victor / Olalde, Jose / Berdiel, Miguel J / Riordan, Neil H / Martinez, Juan Manuel / Gil, Armando / Gonzalez, Michael J

Life (Basel, Switzerland)

2021 Volume 11, Issue 12

Abstract: Currently available anti-viral drugs may be useful in reducing the viral load but are not providing the necessary physiological effects to reduce the SARS-CoV-2 complications efficiently. Treatments that provide better clinical outcomes are urgently ... ...

Abstract	Currently available anti-viral drugs may be useful in reducing the viral load but are not providing the necessary physiological effects to reduce the SARS-CoV-2 complications efficiently. Treatments that provide better clinical outcomes are urgently needed. Vitamin C (ascorbic acid, AA) is an essential nutrient with many biological roles that have been proven to play an important part in immune function; it serves as an antioxidant, an anti-viral, and exerts anti-thrombotic effects among many other physiological benefits. Research has proven that AA at pharmacological doses can be beneficial to patients with acute respiratory distress syndrome (ARDS) and other respiratory illnesses, including sepsis. In addition, High-Dose Intravenous Vitamin C (HDIVC) has proven to be effective in patients with different viral diseases, such as influenza, chikungunya, Zika, and dengue. Moreover, HDIVC has been demonstrated to be very safe. Regarding COVID-19, vitamin C can suppress the cytokine storm, reduce thrombotic complications, and diminish alveolar and vascular damage, among other benefits. Due to these reasons, the use of HDIVC should be seriously considered in complicated COVID-19 patients. In this article, we will emphasize vitamin C's multiple roles in the most prominent pathophysiological processes presented by the COVID-19 disease.
Language	English
Publishing date	2021-12-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life11121341
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Article ; Online: Hemoglobin Kirklareli [Α

Pedroso, G A / Fernandes, P / Jorge, S E D C / Nascimento, P H / Lima, P C / Grigoleto, M R P / Albuquerque, D M / Santos, M N N / Costa, F F / Toro, A A D C / Sonati, M F

Annals of hematology

2019 Volume 98, Issue 12, Page(s) 2853–2855

MeSH term(s)	Brazil ; Child ; Dyspnea/blood ; Dyspnea/genetics ; Hemoglobin A2/genetics ; Hemoglobin A2/metabolism ; Hemoglobins, Abnormal/genetics ; Hemoglobins, Abnormal/metabolism ; Humans ; Male ; Oxygen/blood
Chemical Substances	Hemoglobins, Abnormal ; Hemoglobin A2 (9034-53-1) ; Oxygen (S88TT14065)
Language	English
Publishing date	2019-11-11
Publishing country	Germany
Document type	Case Reports ; Letter
ZDB-ID	1064950-5
ISSN	1432-0584 ; 0939-5555 ; 0945-8077
ISSN (online)	1432-0584
ISSN	0939-5555 ; 0945-8077
DOI	10.1007/s00277-019-03839-z
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