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  1. Book: Lung stem cells in development, health and disease

    Nikolić, Marko Z. / Hogan, Brigid L.M.

    (ERS monograph ; number 91)

    2021  

    Author's details edited by Marko Z. Nikolić and Brigid L.M. Hogan
    Series title ERS monograph ; number 91
    Collection
    Language English
    Size xiii, 378 Seiten, Illustrationen
    Publisher European Respiratory Society
    Publishing place Sheffield
    Publishing country Great Britain
    Document type Book
    Accompanying material Zugang zu access online über Code
    HBZ-ID HT020962504
    ISBN 978-1-84984-133-7 ; 9781849841344 ; 1-84984-133-0 ; 1849841349
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Isolated Spleen Metastases of Endometrial Cancer

    Marko M. Stojanovic / Vesna Brzački / Jelena D. Zivadinovic / Nebojsa S. Ignjatovic / Marko D. Gmijovic / Miodrag N. Djordjevic / Ilija Golubovic / Nada G. Nikolić / Novica Z. Bojanic / Miroslav P. Stojanovic

    Medicina, Vol 58, Iss 592, p

    A Case Report

    2022  Volume 592

    Abstract: Background: Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature. Case Summary: We report a patient with isolated splenic ... ...

    Abstract Background: Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature. Case Summary: We report a patient with isolated splenic metastases of endometrial cancer 3 years after radical surgery of the primary tumor. The patient was successfully treated by splenectomy and six cycles of paclitaxel. Fifty months after splenectomy, she was alive and well, and with no evidence of disease. Conclusion: Isolated spleen metastasis of endometrial cancer is very rare. Radical surgery and adjuvant therapy may offer excellent long-term survival.
    Keywords spleen ; metastases ; endometrial ; cancer ; splenectomy ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Isolated Spleen Metastases of Endometrial Cancer: A Case Report.

    Stojanovic, Marko M / Brzački, Vesna / Zivadinovic, Jelena D / Ignjatovic, Nebojsa S / Gmijovic, Marko D / Djordjevic, Miodrag N / Golubovic, Ilija / Nikolić, Nada G / Bojanic, Novica Z / Stojanovic, Miroslav P

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 5

    Abstract: Background: Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature.: Case summary: We report a patient with isolated ... ...

    Abstract Background: Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature.
    Case summary: We report a patient with isolated splenic metastases of endometrial cancer 3 years after radical surgery of the primary tumor. The patient was successfully treated by splenectomy and six cycles of paclitaxel. Fifty months after splenectomy, she was alive and well, and with no evidence of disease.
    Conclusion: Isolated spleen metastasis of endometrial cancer is very rare. Radical surgery and adjuvant therapy may offer excellent long-term survival.
    MeSH term(s) Endometrial Neoplasms/pathology ; Female ; Humans ; Neoplasms, Second Primary ; Splenectomy ; Splenic Neoplasms/secondary ; Splenic Neoplasms/surgery
    Language English
    Publishing date 2022-04-26
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58050592
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Synthetic scaffolds help airway cells reach maturity.

    Nikolić, Marko Z / Rawlins, Emma L

    eLife

    2016  Volume 5

    Abstract: Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease. ...

    Abstract Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.
    MeSH term(s) Animals ; Cell Differentiation ; Humans ; Lung ; Mice ; Organoids ; Pluripotent Stem Cells
    Language English
    Publishing date 2016-11-01
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.21786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Human lung development: recent progress and new challenges.

    Nikolić, Marko Z / Sun, Dawei / Rawlins, Emma L

    Development (Cambridge, England)

    2018  Volume 145, Issue 16

    Abstract: Recent studies have revealed biologically significant differences between human and mouse lung development, and have reported ... ...

    Abstract Recent studies have revealed biologically significant differences between human and mouse lung development, and have reported new
    MeSH term(s) Adult ; Embryo, Mammalian ; Embryonic Development ; Humans ; Lung/embryology ; Lung/pathology ; Lung Diseases/embryology ; Lung Diseases/pathology ; Models, Biological
    Language English
    Publishing date 2018-08-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 90607-4
    ISSN 1477-9129 ; 0950-1991
    ISSN (online) 1477-9129
    ISSN 0950-1991
    DOI 10.1242/dev.163485
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Lung Organoids and Their Use To Study Cell-Cell Interaction.

    Nikolić, Marko Z / Rawlins, Emma L

    Current pathobiology reports

    2017  Volume 5, Issue 2, Page(s) 223–231

    Abstract: Purpose of review: The lung research field has pioneered the use of organoids for the study of cell-cell interactions.: Recent findings: The use of organoids for airway basal cells is routine. However, the development of organoids for the other ... ...

    Abstract Purpose of review: The lung research field has pioneered the use of organoids for the study of cell-cell interactions.
    Recent findings: The use of organoids for airway basal cells is routine. However, the development of organoids for the other regions of the lung is still in its infancy. Such cultures usually rely on cell-cell interactions between the stem cells and a putative niche cell for their growth and differentiation.
    Summary: The use of co-culture organoid systems has facilitated the in vitro cultivation of previously inaccessible stem cell populations, providing a novel method for dissecting the molecular requirements of these cell-cell interactions. Future technology development will allow the growth of epithelial-only organoids in more defined media and also the introduction of specific non-epithelial cells for the study of cell interactions. These developments will require an improved understanding of the epithelial and non-epithelial cell types present in the lung and their lineage relationships.
    Language English
    Publishing date 2017-04-24
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2167-485X
    ISSN 2167-485X
    DOI 10.1007/s40139-017-0137-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Fank1 and Jazf1 promote multiciliated cell differentiation in the mouse airway epithelium.

    Johnson, Jo-Anne / Watson, Julie K / Nikolić, Marko Z / Rawlins, Emma L

    Biology open

    2018  Volume 7, Issue 4

    Abstract: The airways are lined by secretory and multiciliated cells which function together to remove particles and debris from the respiratory tract. The transcriptome of multiciliated cells has been extensively studied, but the function of many of the genes ... ...

    Abstract The airways are lined by secretory and multiciliated cells which function together to remove particles and debris from the respiratory tract. The transcriptome of multiciliated cells has been extensively studied, but the function of many of the genes identified is unknown. We have established an assay to test the ability of over-expressed transcripts to promote multiciliated cell differentiation in mouse embryonic tracheal explants. Overexpression data indicated that
    Language English
    Publishing date 2018-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2632264-X
    ISSN 2046-6390
    ISSN 2046-6390
    DOI 10.1242/bio.033944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Synthetic scaffolds help airway cells reach maturity

    Marko Z Nikolić / Emma L Rawlins

    eLife, Vol

    2016  Volume 5

    Abstract: Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease. ...

    Abstract Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.
    Keywords organoids ; lung airway ; human pluripotent stem cells ; transplantation ; scaffolds ; Medicine ; R ; Science ; Q ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2016-11-01T00:00:00Z
    Publisher eLife Sciences Publications Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Essential Oils of Morus alba and M. nigra Leaves: Effect of Drying on the Chemical Composition.

    Radulović, Niko S / Miljković, Vojkan M / Mladenović, Marko Z / Nikolić, Goran S

    Natural product communications

    2018  Volume 12, Issue 1, Page(s) 115–118

    Abstract: ... E,E)-geranyl linalool (0.2 - 8.0%), (Z)-bovolide (8.1/) and n-chain alkanes (in total, 17.5 - 52.4 ... acetone, and all isomers of 4,6,8-megastigmatrien-3-one. Also, a rare plant metabolite, (Z)-bovolide ...

    Abstract Detailed GC and GC/MS analyses of essential-oil samples obtained by hydrodistillation of Morus alba L. and M nigra L. leaves (four samples) allowed the identification of 131 constituents representing 95.1 - 96.4% of the total GC peak areas. The most abundant compounds classes were alkanes, diterpenoids, carotenoid-derived compounds and fatty acid-related constituents with trans-phytol (7.9 - 71.2%), (E,E)-geranyl linalool (0.2 - 8.0%), (Z)-bovolide (8.1/) and n-chain alkanes (in total, 17.5 - 52.4%) as the major constituents of the analyzed samples. In general, there were only quantitative differences noted between M nigra essential oils from fresh and dry leaves. The most discernable changes included a variation in the content of the major constituents (e.g. the relative amount of trans-phytol and the total amount of alkanes decreased by 5.8% and ≈ 2%, respectively, while that of (E,E)-geranyl linalool increased by 7.8%). On the other hand, the composition of M. alba essential oil was much more significantly affected by the drying process. The highest quantitative differences were noted for trans-phytol, geranyl acetone, and all isomers of 4,6,8-megastigmatrien-3-one. Also, a rare plant metabolite, (Z)-bovolide, characteristic of leaf senescence, was only identified (8.1%) in the essential oil of M alba dried leaves.
    MeSH term(s) Desiccation ; Gas Chromatography-Mass Spectrometry ; Morus/chemistry ; Oils, Volatile/chemistry ; Plant Leaves/chemistry
    Chemical Substances Oils, Volatile
    Language English
    Publishing date 2018-11-22
    Publishing country United States
    Document type Journal Article
    ISSN 1934-578X
    ISSN 1934-578X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The Effect of Shelter on Oxidative Stress and Aggressive Behavior in Crested Newt Larvae (

    Petrović, Tamara G / Vučić, Tijana Z / Nikolić, Sonja Z / Gavrić, Jelena P / Despotović, Svetlana G / Gavrilović, Branka R / Radovanović, Tijana B / Faggio, Caterina / Prokić, Marko D

    Animals : an open access journal from MDPI

    2020  Volume 10, Issue 4

    Abstract: Shelters are important for animal survival. Provision of adequate hiding places allow animals to express their natural sheltering behavior and it can have different positive effects on cortisol levels, physiological processes and mental performance. ... ...

    Abstract Shelters are important for animal survival. Provision of adequate hiding places allow animals to express their natural sheltering behavior and it can have different positive effects on cortisol levels, physiological processes and mental performance. Although the absence of a refuge activates some stress response, its effect on oxidative stress has not been adequately examined. This study investigated whether the presence/absence of a shelter modifies the oxidative status (the antioxidant system and oxidative damage) and aggressive behavior of crested newt larvae (Triturus macedonicus and its hybrid with
    Language English
    Publishing date 2020-04-01
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani10040603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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