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  1. Article: Sonographic Aeration Scoring Indicates Disease Severity in Critically Ill Patients with COVID-19.

    Marggrander, Daniel T / Simon, Philippe / Schröder, Tobias / Gill-Schuster, Daniel / Mutlak, Haitham

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 22

    Abstract: Aims and methods: We evaluated an ultrasound score from 0 to 32 points in eight pulmonary regions to monitor critically ill COVID-19 patients. The score was correlated to surrogate parameters of disease severity, i.e., the oxygenation index, respiratory ...

    Abstract Aims and methods: We evaluated an ultrasound score from 0 to 32 points in eight pulmonary regions to monitor critically ill COVID-19 patients. The score was correlated to surrogate parameters of disease severity, i.e., the oxygenation index, respiratory support, mortality, plasma interleukin-6, and WHO and ARDS classifications.
    Results: A total of 27 patients were repeatedly examined, and 71 examinations were evaluated. Patients with severe COVID-19 scored higher (median 17) than those with moderate disease (median 11,
    Conclusions: The ultrasound score is a reliable tool that might help monitor disease severity and may help stratify the risk of mortality.
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13223446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lung Ultrasound Findings in Patients with COVID-19.

    Marggrander, Daniel T / Borgans, Frauke / Jacobi, Volkmar / Neb, Holger / Wolf, Timo

    SN comprehensive clinical medicine

    2020  Volume 2, Issue 11, Page(s) 2151–2157

    Abstract: The current SARS-CoV-2 outbreak leads to a growing need of point-of-care thoracic imaging that is compatible with isolation settings and infection prevention precautions. We retrospectively reviewed 17 COVID-19 patients who received point-of-care lung ... ...

    Abstract The current SARS-CoV-2 outbreak leads to a growing need of point-of-care thoracic imaging that is compatible with isolation settings and infection prevention precautions. We retrospectively reviewed 17 COVID-19 patients who received point-of-care lung ultrasound imaging in our isolation unit. Lung ultrasound was able to detect interstitial lung disease effectively; severe cases showed bilaterally distributed B-Lines with or without consolidations; one case showed bilateral pleural plaques. Corresponding to CT scans, interstitial involvement is accurately depicted as B-Lines on lung ultrasound. Lung ultrasound might be suitable for detecting interstitial involvement in a bedside setting under high security isolation precautions.
    Keywords covid19
    Language English
    Publishing date 2020-10-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2947211-8
    ISSN 2523-8973 ; 2523-8973
    ISSN (online) 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00553-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lung Ultrasound Effectively Detects HIV-Associated Interstitial Pulmonary Disease.

    Marggrander, Daniel T / Koç-Günel, Sinem / Tekeli-Camcı, Nesrin / Martin, Simon / Golbach, Rejane / Wolf, Timo

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2021  Volume 111, Page(s) 204–210

    Abstract: Objectives To prospectively evaluate lung ultrasound in comparison with radiography and computed tomography (CT) for detecting HIV-related lung diseases. Methods Ultrasound examinations in HIV-positive patients were evaluated by three raters; available ... ...

    Abstract Objectives To prospectively evaluate lung ultrasound in comparison with radiography and computed tomography (CT) for detecting HIV-related lung diseases. Methods Ultrasound examinations in HIV-positive patients were evaluated by three raters; available conventional imaging was evaluated by another rater. Results were compared with each other and the definite diagnosis. Interrater reliability was calculated for each finding. Results Eighty HIV-positive patients received lung ultrasound examinations; 74 received conventional imaging. The overall sensitivity was 97.5% for CT, 90.7% for ultrasound and 78.1% for radiography. The most common diagnoses were Pneumocystis jirovecii pneumonia (21 cases) and bacterial pneumonia (17 cases). The most frequent and sensitive ultrasonographic findings were interstitial abnormalities indicated by B-lines, independent of the aetiology. Interrater reliability was high for interstitial abnormalities (ICC=0.82). The interrater reliability for consolidations and effusion increased during the study (r=0.88 and r=0.37, respectively). Conclusions Ultrasound is a fast, reliable and sensitive point-of-care tool, particularly in detecting interstitial lung disease, which is common in HIV-associated illness. It does not effectively discriminate between different aetiologies. A longer learning period might be required to reliably identify consolidations and effusions.
    MeSH term(s) HIV Infections/complications ; Humans ; Lung/diagnostic imaging ; Lung Diseases, Interstitial/diagnostic imaging ; Pneumocystis carinii ; Pneumonia, Pneumocystis/diagnostic imaging ; Reproducibility of Results ; Ultrasonography
    Language English
    Publishing date 2021-08-15
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2021.08.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lung Ultrasound Findings in Patients with COVID-19

    Marggrander, Daniel T / Borgans, Frauke / Jacobi, Volkmar / Neb, Holger / Wolf, Timo

    SN Compr Clin Med

    Abstract: The current SARS-CoV-2 outbreak leads to a growing need of point-of-care thoracic imaging that is compatible with isolation settings and infection prevention precautions. We retrospectively reviewed 17 COVID-19 patients who received point-of-care lung ... ...

    Abstract The current SARS-CoV-2 outbreak leads to a growing need of point-of-care thoracic imaging that is compatible with isolation settings and infection prevention precautions. We retrospectively reviewed 17 COVID-19 patients who received point-of-care lung ultrasound imaging in our isolation unit. Lung ultrasound was able to detect interstitial lung disease effectively; severe cases showed bilaterally distributed B-Lines with or without consolidations; one case showed bilateral pleural plaques. Corresponding to CT scans, interstitial involvement is accurately depicted as B-Lines on lung ultrasound. Lung ultrasound might be suitable for detecting interstitial involvement in a bedside setting under high security isolation precautions.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #834146
    Database COVID19

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