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  1. Article ; Online: Lung Ultrasound Point-of-View in Pediatric and Adult COVID-19 Infection.

    Norbedo, Stefania / Blaivas, Michael / Raffaldi, Irene / Caroselli, Costantino

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2020  Volume 40, Issue 5, Page(s) 899–908

    Abstract: From its start in China in December 2019, infection by the new SARS-CoV2 spread fast all over the world. It can present as severe respiratory distress in the elderly or a vasculitis in a child, most of whom are typically completely asymptomatic. This ... ...

    Abstract From its start in China in December 2019, infection by the new SARS-CoV2 spread fast all over the world. It can present as severe respiratory distress in the elderly or a vasculitis in a child, most of whom are typically completely asymptomatic. This makes infection detection based on clinical grounds exceedingly difficult. Lung ultrasound has become an important tool in diagnosis and follow-up of patient with COVID-19 infection.Here we review available, up to date literature on ultrasound use for COVID-19 suspected pediatric patients and contrast it to published findings in adult patients.
    MeSH term(s) Adult ; Aged ; COVID-19 ; Child ; China ; Humans ; Lung/diagnostic imaging ; RNA, Viral ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-09-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.15475
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  2. Article ; Online: Urgent Hospitalizations Related to Viral Respiratory Disease in Children during Autumn and Winter Seasons 2022/2023.

    Peri, Francesca / Lorenzon, Beatrice / Cason, Carolina / Amaddeo, Alessandro / Norbedo, Stefania / Comar, Manola / Barbi, Egidio / Cozzi, Giorgio

    Viruses

    2023  Volume 15, Issue 12

    Abstract: Aim: The loosening of social distancing measures over the past two years has led to a resurgence of seasonal epidemics associated with respiratory viral infections in children. We aim to describe the impact of such infections through urgent ... ...

    Abstract Aim: The loosening of social distancing measures over the past two years has led to a resurgence of seasonal epidemics associated with respiratory viral infections in children. We aim to describe the impact of such infections through urgent hospitalizations in a pediatric emergency department.
    Methods: We performed a retrospective review of medical records of all children and adolescents with a positive nasal swab admitted at the children's hospital IRCCS Burlo Garofolo of Trieste, in Italy, from September 2021 to March 2022, and September 2022 to March 2023.
    Results: Respiratory Syncytial Virus and Influenza viruses accounted for up to 55% of hospitalizations for respiratory infections during the study periods. During the last season, the number of hospitalizations related to the Influenza virus was five times higher than those related to SARS-CoV-2 (25% vs. 5%). Respiratory Syncytial Virus was associated with a greater need for respiratory support, mostly HFNC (High Flow Nasal Cannula).
    Conclusions: Respiratory Syncytial Virus and Influenza virus had a more significant impact on urgent hospitalizations during the past wintery seasons than SARS-CoV-2.
    MeSH term(s) Child ; Adolescent ; Humans ; Seasons ; Respiratory Syncytial Virus Infections/epidemiology ; Virus Diseases/epidemiology ; Respiratory Syncytial Virus, Human ; Orthomyxoviridae ; Hospitalization
    Language English
    Publishing date 2023-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15122425
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  3. Article ; Online: Lung Ultrasound Point-of-View in Pediatric and Adult COVID-19 Infection ; Lung ultrasound and COVID-19

    Norbedo, Stefania / Blaivas, Michael / Raffaldi, Irene / Caroselli, Costantino

    Journal of Ultrasound in Medicine ; ISSN 0278-4297

    2020  

    Keywords Radiological and Ultrasound Technology ; Radiology Nuclear Medicine and imaging ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1002/jum.15475
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Authors' Reply to M.S. Raghuraman: "Intranasal Dexmedetomidine for Procedural Sedation in Children, a Suitable Alternative to Chloral Hydrate".

    Cozzi, Giorgio / Norbedo, Stefania / Barbi, Egidio

    Paediatric drugs

    2017  Volume 19, Issue 4, Page(s) 377

    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Letter ; Comment
    ZDB-ID 1492748-2
    ISSN 1179-2019 ; 1174-5878
    ISSN (online) 1179-2019
    ISSN 1174-5878
    DOI 10.1007/s40272-017-0246-0
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  5. Article: Lung Ultrasound Point-of-View in Pediatric and Adult COVID-19 Infection

    Norbedo, Stefania / Blaivas, Michael / Raffaldi, Irene / Caroselli, Costantino

    J. ultrasound med

    Abstract: From its start in China in December 2019, infection by the new SARS-CoV2 spread fast all over the world. It can present as severe respiratory distress in the elderly or a vasculitis in a child, most of whom are typically completely asymptomatic. This ... ...

    Abstract From its start in China in December 2019, infection by the new SARS-CoV2 spread fast all over the world. It can present as severe respiratory distress in the elderly or a vasculitis in a child, most of whom are typically completely asymptomatic. This makes infection detection based on clinical grounds exceedingly difficult. Lung ultrasound has become an important tool in diagnosis and follow-up of patient with COVID-19 infection.Here we review available, up to date literature on ultrasound use for COVID-19 suspected pediatric patients and contrast it to published findings in adult patients.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32894621
    Database COVID19

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  6. Article ; Online: Intranasal Dexmedetomidine for Procedural Sedation in Children, a Suitable Alternative to Chloral Hydrate.

    Cozzi, Giorgio / Norbedo, Stefania / Barbi, Egidio

    Paediatric drugs

    2017  Volume 19, Issue 2, Page(s) 107–111

    Abstract: Sedation is often required for children undergoing diagnostic procedures. Chloral hydrate has been one of the sedative drugs most used in children over the last 3 decades, with supporting evidence for its efficacy and safety. Recently, chloral hydrate ... ...

    Abstract Sedation is often required for children undergoing diagnostic procedures. Chloral hydrate has been one of the sedative drugs most used in children over the last 3 decades, with supporting evidence for its efficacy and safety. Recently, chloral hydrate was banned in Italy and France, in consideration of evidence of its carcinogenicity and genotoxicity. Dexmedetomidine is a sedative with unique properties that has been increasingly used for procedural sedation in children. Several studies demonstrated its efficacy and safety for sedation in non-painful diagnostic procedures. Dexmedetomidine's impact on respiratory drive and airway patency and tone is much less when compared to the majority of other sedative agents. Administration via the intranasal route allows satisfactory procedural success rates. Studies that specifically compared intranasal dexmedetomidine and chloral hydrate for children undergoing non-painful procedures showed that dexmedetomidine was as effective as and safer than chloral hydrate. For these reasons, we suggest that intranasal dexmedetomidine could be a suitable alternative to chloral hydrate.
    MeSH term(s) Administration, Intranasal ; Child ; Chloral Hydrate/administration & dosage ; Chloral Hydrate/adverse effects ; Dexmedetomidine/administration & dosage ; Dexmedetomidine/adverse effects ; Humans ; Hypnotics and Sedatives/administration & dosage ; Hypnotics and Sedatives/adverse effects
    Chemical Substances Hypnotics and Sedatives ; Chloral Hydrate (418M5916WG) ; Dexmedetomidine (67VB76HONO)
    Language English
    Publishing date 2017-04
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article ; Review
    ZDB-ID 1492748-2
    ISSN 1179-2019 ; 1174-5878
    ISSN (online) 1179-2019
    ISSN 1174-5878
    DOI 10.1007/s40272-017-0217-5
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  7. Article ; Online: Acute Abdominal Pain: Recognition and Management of Constipation in the Emergency Department.

    Norbedo, Stefania / Bassanese, Giulia / Barbieri, Francesca / Barbi, Egidio

    Pediatric emergency care

    2017  Volume 33, Issue 10, Page(s) e75–e78

    Abstract: Objective: The main aim of the study was to investigate the incidence and the clinically relevant features of functional constipation in patients evaluated for acute abdominal pain in a tertiary care pediatric emergency department.: Methods: This is ... ...

    Abstract Objective: The main aim of the study was to investigate the incidence and the clinically relevant features of functional constipation in patients evaluated for acute abdominal pain in a tertiary care pediatric emergency department.
    Methods: This is a retrospective study. We analyzed 4394 medical records and recorded the information (demographics, triage code, symptoms, medical history, physical evaluation, laboratory tests, radiological studies, procedures, and treatments) of all patients admitted for acute abdominal pain to the emergency department of the IRCCS Burlo Garofolo, Trieste, during 2010 to 2013.
    Results: In this study, a quarter of patients (1020) presenting in the emergency department with acute abdominal pain were affected by functional constipation. Acute pain associated with functional constipation is generally rated from moderate to severe, and the location of the pain on physical evaluation was not a sufficient criterion to guide diagnosis. Isolated vomiting may be present in a minority of cases. Digital rectal exploration was never performed; the majority of patients were treated by means of an enema with prompt relief. Six percent of patients with constipation underwent radiological studies.
    Conclusions: This study confirms that the medical history provides a pivotal role in the diagnosis of functional constipation. Digital rectal exploration and x-rays should be avoided in this setting, whereas an enema plays a useful diagnostic and therapeutic role in our study patients.
    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632588-9
    ISSN 1535-1815 ; 0749-5161
    ISSN (online) 1535-1815
    ISSN 0749-5161
    DOI 10.1097/PEC.0000000000001039
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  8. Article ; Online: Drowning in Children and Predictive Parameters: A 15-Year Multicenter Retrospective Analysis.

    Peri, Francesca / De Nardi, Laura / Canuto, Arianna / Gaiero, Alberto / Noli, Serena / Ferretti, Marta / Vergine, Gianluca / Falcioni, Alice / Copponi, Elisabetta / Tagliabue, Bruna / Massart, Francesco / Fabiani, Elisabetta / Stringhi, Carlo / Rubini, Monica / Zamagni, Giulia / Amaddeo, Alessandro / Genovese, Maria Rita / Norbedo, Stefania

    Pediatric emergency care

    2023  Volume 39, Issue 7, Page(s) 516–523

    Abstract: Background: Drowning is a serious and underestimated public health problem, with the highest morbidity and mortality reported among children. Data regarding pediatric outcomes of drowning are often inadequate, and data collection is poorly standardized ... ...

    Abstract Background: Drowning is a serious and underestimated public health problem, with the highest morbidity and mortality reported among children. Data regarding pediatric outcomes of drowning are often inadequate, and data collection is poorly standardized among centers. This study aims to provide an overview of a drowning pediatric population in pediatric emergency department, focusing on its main characteristics and management and evaluating prognostic factors.
    Methods: This is a retrospective multicenter study involving eight Italian Pediatric Emergency Departments. Data about patients between 0 to 16 years of age who drowned between 2006 and 2021 were collected and analyzed according to the Utstein-style guidelines for drowning.
    Results: One hundred thirty-five patients (60.9% males, median age at the event 5; interquartile range, 3-10) were recruited and only those with known outcome were retained for the analysis (133). Nearly 10% had a preexisting medical conditions with epilepsy being the most common comorbidity. One third were hospitalized in the intensive care unit (ICU) and younger males had a higher rate of ICU admission than female peers. Thirty-five patients (26.3%) were hospitalized in a medical ward while 19 (14.3%) were discharged from the emergency department and 11 (8.3%) were discharged after a brief medical observation less than 24 hours. Six patients died (4.5%). Medium stay in the ED was approximately 40 hours. No difference in terms of ICU admission was found between cardiopulmonary resuscitation performed by bystanders or trained medical personnel ( P = 0.388 vs 0.390).
    Conclusions: This study offers several perspectives on ED victims who drowned. One of the major finding is that no difference in outcomes was seen in patients who received cardiopulmonary resuscitation performed by bystanders or medical services, highlighting the importance of a prompt intervention.
    MeSH term(s) Male ; Child ; Humans ; Female ; Drowning/epidemiology ; Cardiopulmonary Resuscitation ; Retrospective Studies ; Hospitalization ; Patient Discharge ; Near Drowning/epidemiology ; Near Drowning/therapy
    Language English
    Publishing date 2023-06-18
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 632588-9
    ISSN 1535-1815 ; 0749-5161
    ISSN (online) 1535-1815
    ISSN 0749-5161
    DOI 10.1097/PEC.0000000000002987
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  9. Article ; Online: Red Flags in Torticollis: A Historical Cohort Study.

    Starc, Meta / Norbedo, Stefania / Tubaro, Martina / Ronfani, Luca / Bassanese, Giulia / Barbi, Egidio

    Pediatric emergency care

    2018  Volume 34, Issue 7, Page(s) 463–466

    Abstract: Objective: This study aimed to assess the spectrum of pathologies responsible for torticollis in children presenting to the emergency department and to evaluate the associated symptoms to determine clinical red flags for hospitalization.: Methods: ... ...

    Abstract Objective: This study aimed to assess the spectrum of pathologies responsible for torticollis in children presenting to the emergency department and to evaluate the associated symptoms to determine clinical red flags for hospitalization.
    Methods: This was a historical retrospective cohort study. Medical records of children evaluated in our emergency department for torticollis from 2008 to 2013 were reviewed.
    Results: Among 392 identified patients, 61% had postural torticollis,19.4% infection related, 16.3% traumatic, and 3.5% other. Twenty-five patients (6.4%) were hospitalized. Four variables were strongly and independently related to the severe outcome: fever, sore throat, headache, and age.
    Conclusions: The association of 2 or 3 of these 4 features carried a risk of 32% and 58%, respectively, of having a severe illness.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Cohort Studies ; Emergency Service, Hospital/statistics & numerical data ; Female ; Hospitalization/statistics & numerical data ; Humans ; Male ; Retrospective Studies ; Torticollis/etiology
    Language English
    Publishing date 2018-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632588-9
    ISSN 1535-1815 ; 0749-5161
    ISSN (online) 1535-1815
    ISSN 0749-5161
    DOI 10.1097/PEC.0000000000001377
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  10. Article ; Online: A child with macroscopic crystalluria: Questions.

    Pellegrin, Maria Chiara / Di Mascio, Alberto / Norbedo, Stefania / Pennesi, Marco / Barbi, Egidio

    Pediatric nephrology (Berlin, Germany)

    2017  Volume 33, Issue 5, Page(s) 813–814

    MeSH term(s) Amoxicillin/adverse effects ; Amoxicillin/therapeutic use ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Child ; Humans ; Male ; Urinalysis/methods ; Urinary Calculi/etiology
    Chemical Substances Anti-Bacterial Agents ; Amoxicillin (804826J2HU)
    Language English
    Publishing date 2017-08-11
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-017-3757-6
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