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  1. Article ; Online: Lung ultrasound for diagnosis and management of ARDS.

    Smit, Marry R / Mayo, Paul H / Mongodi, Silvia

    Intensive care medicine

    2024  

    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Editorial
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07422-7
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    Zs.A 1089: Show issues Location:
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  2. Article ; Online: Memories of ICU stay in patients admitted for severe COVID-19.

    Salve, Giulia / Mongodi, Silvia / Mangiagalli, Matteo / Tintim Lobato, Carolina / Mojoli, Francesco

    Intensive care medicine

    2024  Volume 50, Issue 4, Page(s) 602–604

    MeSH term(s) Humans ; COVID-19 ; Critical Care ; Intensive Care Units ; Patients ; Hospitalization
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07365-z
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    Zs.A 1089: Show issues Location:
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  3. Article ; Online: Lung ultrasound training: how short is too short? observational study on the effects of a focused theoretical training for novice learners.

    Mongodi, Silvia / Arioli, Raffaella / Quaini, Attilio / Grugnetti, Giuseppina / Grugnetti, Anna Maria / Mojoli, Francesco

    BMC medical education

    2024  Volume 24, Issue 1, Page(s) 166

    Abstract: Background: Lung ultrasound has been increasingly used in the last years for the assessment of patients with respiratory diseases; it is considered a simple technique, now spreading from physicians to other healthcare professionals as nurses and ... ...

    Abstract Background: Lung ultrasound has been increasingly used in the last years for the assessment of patients with respiratory diseases; it is considered a simple technique, now spreading from physicians to other healthcare professionals as nurses and physiotherapists, as well as to medical students. These providers may require a different training to acquire lung ultrasound skills, since they are expected to have no previous experience with ultrasound. The aim of the study was to assess the impact of a short theoretical training focused on lung ultrasound pattern recognition in a population of novice nurse learners with no previous experience with ultrasound.
    Methods: We included the nurses attending a critical care advanced course for nurses performed at the University of Pavia. Images' interpretation skills were tested on two slide sets (a 25-clip set focused on B-pattern recognition and a 25-clip set focused on identification of pleural movement as lung sliding, lung pulse, lung point, no movement) before and after three 30-minute teaching modules dedicated to general ultrasound principles, B-lines assessment and lung sliding assessment. A cut off of 80% was considered acceptable for correctly interpreted images after this basic course.
    Results: 22 nurses were enrolled (age 26.0 [24.0-28.0] years; men 4 (18%)); one nurse had previous experience with other ultrasound techniques, none of them had previous experience with lung ultrasound. After the training, the number of correctly interpreted clips improved from 3.5 [0.0-13.0] to 22.0 [19.0-23.0] (p < 0.0001) for B-pattern and from 0.5 [0.0-2.0] to 8.5 [6.0-12.0] (p < 0.0001) for lung sliding assessment. The number of correct answers for B-pattern recognition was significantly higher than for lung sliding assessment, both before (3.5 [0.0-13.0] vs. 0.5 [0.0-2.0]; p = 0.0036) and after (22.0 [19.0-23.0] vs. 8.5 [6.0-12.0]; p < 0.0001) the training. After the training, nurses were able to correctly recognize the presence or the absence of a B-pattern in 84.2 ± 10.3% of cases; lung sliding was correctly assessed in 37.1 ± 15.3% of cases.
    Conclusions: Lung ultrasound is considered a simple technique; while a short, focused training significantly improves B-pattern recognition, lung sliding assessment may require a longer training for novice learners.
    Trial registration: Not applicable.
    MeSH term(s) Male ; Humans ; Adult ; Lung/diagnostic imaging ; Ultrasonography ; Physicians
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-024-05148-0
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  4. Article ; Online: The weaning from mechanical ventilation: a comprehensive ultrasound approach.

    Santangelo, Erminio / Mongodi, Silvia / Bouhemad, Bélaid / Mojoli, Francesco

    Current opinion in critical care

    2022  Volume 28, Issue 3, Page(s) 322–330

    Abstract: Purpose of review: Due to heart, lung and diaphragm interactions during weaning from mechanical ventilation, an ultrasound integrated approach may be useful in the detection of dysfunctions potentially leading to weaning failure. In this review, we will ...

    Abstract Purpose of review: Due to heart, lung and diaphragm interactions during weaning from mechanical ventilation, an ultrasound integrated approach may be useful in the detection of dysfunctions potentially leading to weaning failure. In this review, we will summarize the most recent advances concerning the ultrasound applications relevant to the weaning from mechanical ventilation.
    Recent findings: The role of ultrasonographic examination of heart, lung and diaphragm has been deeply investigated over the years. Most recent findings concern the ability of lung ultrasound in detecting weaning induced pulmonary edema during spontaneous breathing trial. Furthermore, in patients at high risk of cardiac impairments, global and anterolateral lung ultrasound scores have been correlated with weaning and extubation failure, whereas echocardiographic indexes were not. For diaphragmatic ultrasound evaluation, new indexes have been proposed for the evaluation of diaphragm performance during weaning, but further studies are needed to validate these results.
    Summary: The present review summarizes the potential role of ultrasonography in the weaning process. A multimodal integrated approach allows the clinician to comprehend the pathophysiological processes of weaning failure.
    MeSH term(s) Airway Extubation ; Diaphragm/diagnostic imaging ; Humans ; Respiration, Artificial/adverse effects ; Ultrasonography/methods ; Ventilator Weaning/adverse effects ; Ventilator Weaning/methods
    Language English
    Publishing date 2022-03-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000941
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  5. Article ; Online: Defining basic (lung) ultrasound skills; not so basic after all? Author's reply.

    Mongodi, Silvia / Wong, Adrian / Baron, Antoine Vieillard / Robba, Chiara

    Intensive care medicine

    2022  Volume 48, Issue 5, Page(s) 630–631

    MeSH term(s) Humans ; Lung/diagnostic imaging ; Thorax ; Ultrasonography
    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06682-5
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    Zs.A 1089: Show issues Location:
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  6. Article: Respiratory failure due to concomitant interstitial lung disease and diaphragmatic involvement in a patient with anti-MDA5 dermatomyositis: a case report.

    Grignaschi, Silvia / Mongodi, Silvia / Alfonsi, Enrico / Mojoli, Francesco / Vertui, Valentina / Zanframundo, Giovanni / Cavagna, Lorenzo

    Clinical and experimental rheumatology

    2022  Volume 40 Suppl 134, Issue 5, Page(s) 121–123

    Abstract: Diaphragm myositis is a rare manifestation of idiopathic inflammatory myopathies, barely portrayed in literature despite its potential severity. We describe a 57-year-old Caucasian male with anti-MDA5 positive dermatomyositis, that had a 4-month history ... ...

    Abstract Diaphragm myositis is a rare manifestation of idiopathic inflammatory myopathies, barely portrayed in literature despite its potential severity. We describe a 57-year-old Caucasian male with anti-MDA5 positive dermatomyositis, that had a 4-month history of progressive dyspnoea requiring oxygen-therapy, scarcely responsive to prednisolone. Chest high resolution computed tomography (HRCT) showed mild interstitial lung disease (ILD), whereas pulmonary function tests evidenced severe restrictive syndrome with high lung ultrasound score. Diaphragm ultrasound revealed a marked diaphragm dysmotility, confirmed by electromyography (EMG). The patient was treated with intravenous immunoglobulins and mofetil mycophenolate with progressive improvement of dyspnoea, lung volumes and ILD at CT scan. Ultrasound examination also revealed marked improvement of the diaphragmatic disfunction and a reduction of lung ultrasound score. The use of ultrasound may provide a valuable tool in the diagnosis of diaphragm myositis, which may play a major role in the respiratory impairment of these patients. A combined lung and diaphragm examination allowed bedside monitoring of the improvements in both lung aeration and diaphragm contractility.
    MeSH term(s) Autoantibodies ; Dermatomyositis/complications ; Dermatomyositis/drug therapy ; Diaphragm/diagnostic imaging ; Dyspnea ; Humans ; Interferon-Induced Helicase, IFIH1 ; Lung Diseases, Interstitial/complications ; Lung Diseases, Interstitial/diagnostic imaging ; Lung Diseases, Interstitial/drug therapy ; Male ; Middle Aged ; Myositis/diagnosis ; Myositis/diagnostic imaging ; Respiratory Insufficiency/diagnostic imaging ; Respiratory Insufficiency/etiology ; Respiratory Insufficiency/therapy
    Chemical Substances Autoantibodies ; Interferon-Induced Helicase, IFIH1 (EC 3.6.4.13)
    Language English
    Publishing date 2022-02-10
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/0u7vdc
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  7. Article ; Online: Left ventricular diastolic dysfunction as a predictor of weaning failure from mechanical ventilation. Author's reply.

    Bouhemad, Bélaid / Mojoli, Francesco / Mongodi, Silvia

    Intensive care medicine

    2020  Volume 46, Issue 11, Page(s) 2123

    MeSH term(s) Aged ; Humans ; Lung ; Pilot Projects ; Respiration, Artificial/adverse effects ; Ventilator Weaning ; Ventricular Dysfunction, Left
    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06239-4
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    Zs.A 1089: Show issues Location:
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  8. Article ; Online: Lung ultrasound modifications induced by fibreoptic bronchoscopy may improve early bedside ventilator-associated pneumonia diagnosis: A case series.

    Mojoli, Francesco / Bouhemad, Bélaïd / Volpicelli, Giovanni / Mongodi, Silvia

    European journal of anaesthesiology

    2020  Volume 37, Issue 10, Page(s) 946–949

    MeSH term(s) Bronchi ; Bronchoscopy ; Fiber Optic Technology ; Humans ; Lung/diagnostic imaging ; Pneumonia, Ventilator-Associated/diagnosis ; Ultrasonography
    Language English
    Publishing date 2020-06-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 605770-6
    ISSN 1365-2346 ; 0265-0215
    ISSN (online) 1365-2346
    ISSN 0265-0215
    DOI 10.1097/EJA.0000000000001254
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  9. Article ; Online: High prevalence of acute stress disorder and persisting symptoms in ICU survivors after COVID-19.

    Mongodi, Silvia / Salve, Giulia / Tavazzi, Guido / Politi, Pierluigi / Mojoli, Francesco

    Intensive care medicine

    2021  Volume 47, Issue 5, Page(s) 616–618

    MeSH term(s) COVID-19 ; Humans ; Intensive Care Units ; Prevalence ; SARS-CoV-2 ; Stress Disorders, Post-Traumatic/epidemiology ; Stress Disorders, Post-Traumatic/etiology ; Stress Disorders, Traumatic, Acute ; Survivors
    Language English
    Publishing date 2021-03-17
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-021-06349-7
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  10. Article ; Online: The Role of Perfluorinated Compound Pollution in the Development of Acute and Chronic Kidney Disease.

    Ferrari, Fiorenza / Manera, Miriam / Mongodi, Silvia / Esposito, Pasquale / Ronco, Claudio

    Contributions to nephrology

    2021  Volume 199, Page(s) 285–296

    Abstract: Clinical Background: Poly- and perfluorinated compound (PFCS) pollution has been found to be the driver of different diseases, including glucose intolerance, hyperlipidemia, thyroid diseases, gestational diabetes mellitus and hypertension, testicular and ...

    Abstract Clinical Background: Poly- and perfluorinated compound (PFCS) pollution has been found to be the driver of different diseases, including glucose intolerance, hyperlipidemia, thyroid diseases, gestational diabetes mellitus and hypertension, testicular and genitourinary cancer, as well as impaired kidney function. This review focuses on the renal effects of PFCS, intending to clarify their occurrence and pathogenetic mechanisms. Epidemiology: Between October 31st, 2017, and March 31st, 2020, most frequently analyzed PFCS were perfluorooctane sulfonate, perfluorooctanoic acid, sodium perfluoro-1-hexanesulfonate, perfluoro-n-nonanoic acid, and perfluoro-n-decanoic acid. Unfortunately, the novel replacement compounds (e.g., perfluoroether carboxylic acid) are unregulated, and they are not under study. PFCS are linked with an impaired kidney function: the kidney is a target of PFCS because it is involved in their excretion. Inter- and intra-species variations exist and affect PFCS pharmacokinetics, leading to different risk profiles of adverse effects, even at similar exposures, and influencing the risk of renal damage in case of concomitant exposure to PFCS and some heavy metals. Challenges, Prevention and Treatment: In the last 20 years, much effort has been made to stop the PFCS production in Europe and USA. However, human exposure remains persistently high due to PFCS long half-life, the large-scale production in some countries and the unregulated novel compounds. This context makes further studies mandatory to understand the pathogenetic mechanisms of old and new PFCS and the effective strategies to remove PFCS from the human blood in the most affected areas of the world.
    MeSH term(s) Europe ; Humans ; Renal Insufficiency, Chronic/chemically induced
    Language English
    Publishing date 2021-08-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 1662-2782 ; 0302-5144
    ISSN (online) 1662-2782
    ISSN 0302-5144
    DOI 10.1159/000517711
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