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  1. Article ; Online: Scintigraphic Diagnosis of Acute Pulmonary Embolism: From Basics to Best Practices.

    Le Roux, Pierre-Yves / Le Pennec, Romain / Salaun, Pierre-Yves / Zuckier, Lionel S

    Seminars in nuclear medicine

    2023  Volume 53, Issue 6, Page(s) 743–751

    Abstract: In this article the technique, interpretation, and diagnostic performance of scintigraphy for the diagnosis of acute pulmonary embolism (PE) are reviewed. Lung scintigraphy has stood the test of time as a reliable and validated examination for the ... ...

    Abstract In this article the technique, interpretation, and diagnostic performance of scintigraphy for the diagnosis of acute pulmonary embolism (PE) are reviewed. Lung scintigraphy has stood the test of time as a reliable and validated examination for the determination of PE. Ventilation/perfusion (V/Q) lung scintigraphy assesses the functional consequences of the clot on its downstream vascular bed in conjunction with the underlying ventilatory status of the affected lung region, in contrast to CT pulmonary angiography (CTPA), which visualizes presence of the clot within affected vessels. Most-commonly used ventilation radiopharmaceuticals are Technetium-99m labeled aerosols (such as
    MeSH term(s) Female ; Pregnancy ; Humans ; Radiopharmaceuticals ; Pulmonary Embolism/diagnostic imaging ; Lung ; Radionuclide Imaging ; Technetium Tc 99m Pentetate
    Chemical Substances Radiopharmaceuticals ; Technetium Tc 99m Pentetate (VW78417PU1)
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 120248-0
    ISSN 1558-4623 ; 0001-2998
    ISSN (online) 1558-4623
    ISSN 0001-2998
    DOI 10.1053/j.semnuclmed.2023.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 763: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Systemic Artery to Pulmonary Artery Shunt Mimicking Acute Pulmonary Embolism, Unmasked by a Multimodality Imaging Approach.

    Dissaux, Brieg / Le Floch, Pierre-Yves / Le Pennec, Romain / Tromeur, Cécile / Le Roux, Pierre-Yves

    Tomography (Ann Arbor, Mich.)

    2022  Volume 8, Issue 1, Page(s) 175–179

    Abstract: In this report, we describe the functional imaging findings of systemic artery to pulmonary artery shunt in V/Q SPECT CT imaging. A 63-year-old man with small-cell lung cancer underwent CT pulmonary angiography (CTPA) for suspected acute pulmonary ... ...

    Abstract In this report, we describe the functional imaging findings of systemic artery to pulmonary artery shunt in V/Q SPECT CT imaging. A 63-year-old man with small-cell lung cancer underwent CT pulmonary angiography (CTPA) for suspected acute pulmonary embolism (PE). The CTPA showed an isolated segmental filling defect in the right lower lobe, which was initially interpreted as positive for PE but was actually the consequence of a systemic artery to pulmonary artery shunt due to the recruitment of the bronchial arterial network by the adjacent tumor. A V/Q SPECT/CT scan was also performed, demonstrating a matched perfusion/ventilation defect in the right lower lobe.
    MeSH term(s) Angiography/methods ; Computed Tomography Angiography/methods ; Humans ; Lung ; Male ; Middle Aged ; Pulmonary Artery/diagnostic imaging ; Pulmonary Embolism/diagnostic imaging
    Language English
    Publishing date 2022-01-07
    Publishing country Switzerland
    Document type Case Reports
    ISSN 2379-139X
    ISSN (online) 2379-139X
    DOI 10.3390/tomography8010014
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  3. Article ; Online: Lung scintigraphy for pulmonary embolism diagnosis during the COVID-19 pandemic: does the benefit-risk ratio really justify omitting the ventilation study?

    Le Roux, Pierre-Yves / Le Gal, Grégoire / Salaun, Pierre-Yves

    European journal of nuclear medicine and molecular imaging

    2020  Volume 47, Issue 11, Page(s) 2499–2500

    MeSH term(s) Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Humans ; Odds Ratio ; Pandemics ; Pneumonia, Viral ; Pulmonary Embolism ; SARS-CoV-2 ; Tomography, Emission-Computed, Single-Photon ; Ventilation-Perfusion Ratio
    Keywords covid19
    Language English
    Publishing date 2020-07-22
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-020-04964-y
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1227: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article: Lung Stereotactic Body Radiation Therapy in a Patient with Severe Lung Function Impairment Allowed by Gallium-68 Perfusion PET/CT Imaging: A Case Report.

    Lucia, François / Hamya, Mohamed / Pinot, Fanny / Bourhis, David / Le Roux, Pierre-Yves

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 4

    Abstract: Lung stereotactic body radiotherapy (SBRT) is increasingly proposed, especially for patients with poor lung function who are not eligible for surgery. However, radiation-induced lung injury remains a significant treatment-related adverse event in these ... ...

    Abstract Lung stereotactic body radiotherapy (SBRT) is increasingly proposed, especially for patients with poor lung function who are not eligible for surgery. However, radiation-induced lung injury remains a significant treatment-related adverse event in these patients. Moreover, for patients with very severe COPD, we have very few data about the safety of SBRT for lung cancer. We present the case of a female with very severe chronic obstructive pulmonary disease (COPD) with a forced expiratory volume in one second (FEV1) of 0.23 L (11%), for whom a localized lung tumor was found. Lung SBRT was the only possible treatment. It was allowed and safely performed, based on a pre-therapeutic evaluation of regional lung function with Gallium-68 perfusion lung positron emission tomography combined with computed tomography (PET/CT). This is the first case report to highlight the potential use of a Gallium-68 perfusion PET/CT in order to safely select patients with very severe COPD who can benefit from SBRT.
    Language English
    Publishing date 2023-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13040718
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  5. Article: Radiopharmaceutical Labelling for Lung Ventilation/Perfusion PET/CT Imaging: A Review of Production and Optimization Processes for Clinical Use.

    Blanc-Béguin, Frédérique / Hennebicq, Simon / Robin, Philippe / Tripier, Raphaël / Salaün, Pierre-Yves / Le Roux, Pierre-Yves

    Pharmaceuticals (Basel, Switzerland)

    2022  Volume 15, Issue 5

    Abstract: Lung ventilation/perfusion (V/Q) positron emission tomography-computed tomography (PET/CT) is a promising imaging modality for regional lung function assessment. The same carrier molecules as a conventional V/Q scan (i.e., carbon nanoparticles for ... ...

    Abstract Lung ventilation/perfusion (V/Q) positron emission tomography-computed tomography (PET/CT) is a promising imaging modality for regional lung function assessment. The same carrier molecules as a conventional V/Q scan (i.e., carbon nanoparticles for ventilation and macro aggregated albumin particles for perfusion) are used, but they are labeled with gallium-68 (
    Language English
    Publishing date 2022-04-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph15050518
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  6. Article: Assessment of Image Quality and Lesion Detectability With Digital PET/CT System.

    Delcroix, Olivier / Bourhis, David / Keromnes, Nathalie / Robin, Philippe / Le Roux, Pierre-Yves / Abgral, Ronan / Salaun, Pierre-Yves / Querellou, Solène

    Frontiers in medicine

    2021  Volume 8, Page(s) 629096

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2021-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.629096
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  7. Article ; Online: Interobserver agreement of

    Robin, Philippe / Grewal, Ravinder K / Le Roux, Pierre-Yves / Le Gal, Grégoire / Salaun, Pierre-Yves

    Thrombosis research

    2020  Volume 188, Page(s) 25–27

    MeSH term(s) Early Detection of Cancer ; Fluorodeoxyglucose F18 ; Humans ; Neoplasms ; Observer Variation ; Positron-Emission Tomography ; Radiopharmaceuticals ; Venous Thromboembolism/diagnostic imaging
    Chemical Substances Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2020-01-30
    Publishing country United States
    Document type Letter
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2020.01.028
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 863: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Systemic Artery to Pulmonary Artery Shunt Mimicking Acute Pulmonary Embolism, Unmasked by a Multimodality Imaging Approach

    Brieg Dissaux / Pierre-Yves Le Floch / Romain Le Pennec / Cécile Tromeur / Pierre-Yves Le Roux

    Tomography, Vol 8, Iss 14, Pp 175-

    2022  Volume 179

    Abstract: In this report, we describe the functional imaging findings of systemic artery to pulmonary artery shunt in V/Q SPECT CT imaging. A 63-year-old man with small-cell lung cancer underwent CT pulmonary angiography (CTPA) for suspected acute pulmonary ... ...

    Abstract In this report, we describe the functional imaging findings of systemic artery to pulmonary artery shunt in V/Q SPECT CT imaging. A 63-year-old man with small-cell lung cancer underwent CT pulmonary angiography (CTPA) for suspected acute pulmonary embolism (PE). The CTPA showed an isolated segmental filling defect in the right lower lobe, which was initially interpreted as positive for PE but was actually the consequence of a systemic artery to pulmonary artery shunt due to the recruitment of the bronchial arterial network by the adjacent tumor. A V/Q SPECT/CT scan was also performed, demonstrating a matched perfusion/ventilation defect in the right lower lobe.
    Keywords Computerized Tomography (CT) ; imaging ; diagnostic testing ; embolism ; vascular disease ; Computer applications to medicine. Medical informatics ; R858-859.7
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: A Feasibility Study of Functional Lung Volume Preservation during Stereotactic Body Radiotherapy Guided by Gallium-

    Lucia, François / Hamya, Mohamed / Pinot, Fanny / Goasduff, Gaëlle / Blanc-Béguin, Frédérique / Bourhis, David / Pradier, Olivier / Lucia, Anne-Sophie / Hennebicq, Simon / Mauguen, Maëlle / Floch, Romain / Schick, Ulrike / Bourbonne, Vincent / Salaün, Pierre-Yves / Le Roux, Pierre-Yves

    Cancers

    2023  Volume 15, Issue 6

    Abstract: The aim of this study was to assess the feasibility of sparing functional lung areas by integration of pulmonary functional mapping guided ... ...

    Abstract The aim of this study was to assess the feasibility of sparing functional lung areas by integration of pulmonary functional mapping guided by
    Language English
    Publishing date 2023-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15061726
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  10. Article ; Online: Radiopharmaceutical Labelling for Lung Ventilation/Perfusion PET/CT Imaging

    Frédérique Blanc-Béguin / Simon Hennebicq / Philippe Robin / Raphaël Tripier / Pierre-Yves Salaün / Pierre-Yves Le Roux

    Pharmaceuticals, Vol 15, Iss 518, p

    A Review of Production and Optimization Processes for Clinical Use

    2022  Volume 518

    Abstract: Lung ventilation/perfusion (V/Q) positron emission tomography-computed tomography (PET/CT) is a promising imaging modality for regional lung function assessment. The same carrier molecules as a conventional V/Q scan (i.e., carbon nanoparticles for ... ...

    Abstract Lung ventilation/perfusion (V/Q) positron emission tomography-computed tomography (PET/CT) is a promising imaging modality for regional lung function assessment. The same carrier molecules as a conventional V/Q scan (i.e., carbon nanoparticles for ventilation and macro aggregated albumin particles for perfusion) are used, but they are labeled with gallium-68 ( 68 Ga) instead of technetium-99m ( 99m Tc). For both radiopharmaceuticals, various production processes have been proposed. This article discusses the challenges associated with the transition from 99m Tc- to 68 Ga-labelled radiopharmaceuticals. The various production and optimization processes for both radiopharmaceuticals are reviewed and discussed for optimal clinical use.
    Keywords V/Q PET/CT ; [ 68 Ga]Ga-MAA ; 68 Ga-labelled carbon nanoparticles ; Medicine ; R ; Pharmacy and materia medica ; RS1-441
    Subject code 333
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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