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  1. Article ; Online: Trick or Trap? Reply to Vertical Artifacts as Lung Ultrasound Signs.

    Smargiassi, Andrea / Zanforlin, Alessandro / Tursi, Francesco / Soldati, Gino / Inchingolo, Riccardo

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2023  Volume 43, Issue 1, Page(s) 215–216

    MeSH term(s) Humans ; Artifacts ; Lung/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2023-09-21
    Publishing country England
    Document type Letter
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16337
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  2. Article ; Online: Reply to Colorimetric Triage for Patients with COVID-19.

    Soldati, Gino / Smargiassi, Andrea / Inchingolo, Riccardo / Demi, Libertario

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2020  Volume 40, Issue 4, Page(s) 863–864

    MeSH term(s) COVID-19 ; Colorimetry ; Humans ; Lung ; SARS-CoV-2 ; Triage
    Keywords covid19
    Language English
    Publishing date 2020-08-27
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.15460
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  3. Article ; Online: Reply.

    Inchingolo, Riccardo / Smargiassi, Andrea / Soldati, Gino / Demi, Libertario

    American journal of obstetrics and gynecology

    2020  Volume 223, Issue 4, Page(s) 616

    MeSH term(s) Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus ; Coronavirus Infections/diagnosis ; Female ; Humans ; Pandemics ; Pneumonia ; Pneumonia, Viral ; Pregnancy ; Pregnancy Complications, Infectious ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2020.06.034
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  4. Article ; Online: State of the Art in Lung Ultrasound, Shifting from Qualitative to Quantitative Analyses.

    Mento, Federico / Khan, Umair / Faita, Francesco / Smargiassi, Andrea / Inchingolo, Riccardo / Perrone, Tiziano / Demi, Libertario

    Ultrasound in medicine & biology

    2022  Volume 48, Issue 12, Page(s) 2398–2416

    Abstract: Lung ultrasound (LUS) has been increasingly expanding since the 1990s, when the clinical relevance of vertical artifacts was first reported. However, the massive spread of LUS is only recent and is associated with the coronavirus disease 2019 (COVID-19) ... ...

    Abstract Lung ultrasound (LUS) has been increasingly expanding since the 1990s, when the clinical relevance of vertical artifacts was first reported. However, the massive spread of LUS is only recent and is associated with the coronavirus disease 2019 (COVID-19) pandemic, during which semi-quantitative computer-aided techniques were proposed to automatically classify LUS data. In this review, we discuss the state of the art in LUS, from semi-quantitative image analysis approaches to quantitative techniques involving the analysis of radiofrequency data. We also discuss recent in vitro and in silico studies, as well as research on LUS safety. Finally, conclusions are drawn highlighting the potential future of LUS.
    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Pandemics ; Lung/diagnostic imaging ; Ultrasonography/methods
    Language English
    Publishing date 2022-09-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 186150-5
    ISSN 1879-291X ; 0301-5629
    ISSN (online) 1879-291X
    ISSN 0301-5629
    DOI 10.1016/j.ultrasmedbio.2022.07.007
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    Zs.A 963: Show issues Location:
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  5. Article: Possible Role of Chest Ultrasound in the Assessment of Costo-Phrenic Angle Lesions Prior to Medical Thoracoscopy: A Retrospective Pilot Case Series.

    Conte, Emanuele Giovanni / Smargiassi, Andrea / Lococo, Filippo / Marchetti, Giampietro / Inchingolo, Riccardo

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 11

    Abstract: Background: Pleural malignancy (PM) and malignant pleural effusion (MPE) represent an increasing burden of diseases. Costo-phrenic angle (CPA) could be involved by malignant small nodularities or thickenings in the case of MPE. The aim of this study was ... ...

    Abstract Background: Pleural malignancy (PM) and malignant pleural effusion (MPE) represent an increasing burden of diseases. Costo-phrenic angle (CPA) could be involved by malignant small nodularities or thickenings in the case of MPE. The aim of this study was to evaluate whether lung ultrasound (LUS), performed prior to medical thoracoscopy (MT), could detect pleural abnormalities in CPA not easily detectable by chest computed tomography scan (CCT). Methods: Patients suspected for PM and MPE were retrospectively recruited. Patients underwent both LUS examination with a linear array and CCT prior to diagnostic medical thoracoscopy. LUS pathological findings in CPA were compared with pathological findings detected by CCT. Findings were confirmed by subsequent MT, the gold standard for PMs. Results: Twenty-eight patients were recruited. LUS detected 23 cases of pleural abnormalities in CPA. CCT was detected 12 pleural abnormalities. Inter-rater agreement between the two techniques was minimal (Cohen’s Kappa: 0.28). MT detected PMs in CPA in 22 patients. LUS had a sensitivity of 100% and specificity of 83%. CCT had a sensitivity of 54% and specificity of 100%. A better sensitivity for CCT was reached analysing only all abnormalities > 5 mm (64.3%). Conclusions: LUS examination, in the case of PMs, could change and speed up diagnostic workup.
    Language English
    Publishing date 2022-10-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12112587
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  6. Article ; Online: Human-to-AI Interrater Agreement for Lung Ultrasound Scoring in COVID-19 Patients.

    Fatima, Noreen / Mento, Federico / Zanforlin, Alessandro / Smargiassi, Andrea / Torri, Elena / Perrone, Tiziano / Demi, Libertario

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2022  Volume 42, Issue 4, Page(s) 843–851

    Abstract: Objectives: Lung ultrasound (LUS) has sparked significant interest during COVID-19. LUS is based on the detection and analysis of imaging patterns. Vertical artifacts and consolidations are some of the recognized patterns in COVID-19. However, the ... ...

    Abstract Objectives: Lung ultrasound (LUS) has sparked significant interest during COVID-19. LUS is based on the detection and analysis of imaging patterns. Vertical artifacts and consolidations are some of the recognized patterns in COVID-19. However, the interrater reliability (IRR) of these findings has not been yet thoroughly investigated. The goal of this study is to assess IRR in LUS COVID-19 data and determine how many LUS videos and operators are required to obtain a reliable result.
    Methods: A total of 1035 LUS videos from 59 COVID-19 patients were included. Videos were randomly selected from a dataset of 1807 videos and scored by six human operators (HOs). The videos were also analyzed by artificial intelligence (AI) algorithms. Fleiss' kappa coefficient results are presented, evaluated at both the video and prognostic levels.
    Results: Findings show a stable agreement when evaluating a minimum of 500 videos. The statistical analysis illustrates that, at a video level, a Fleiss' kappa coefficient of 0.464 (95% confidence interval [CI] = 0.455-0.473) and 0.404 (95% CI = 0.396-0.412) is obtained for pairs of HOs and for AI versus HOs, respectively. At prognostic level, a Fleiss' kappa coefficient of 0.505 (95% CI = 0.448-0.562) and 0.506 (95% CI = 0.458-0.555) is obtained for pairs of HOs and for AI versus HOs, respectively.
    Conclusions: To examine IRR and obtain a reliable evaluation, a minimum of 500 videos are recommended. Moreover, the employed AI algorithms achieve results that are comparable with HOs. This research further provides a methodology that can be useful to benchmark future LUS studies.
    MeSH term(s) Humans ; COVID-19 ; Artificial Intelligence ; Reproducibility of Results ; Lung/diagnostic imaging ; Ultrasonography/methods
    Language English
    Publishing date 2022-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16052
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  7. Article ; Online: Reply.

    Perrone, Tiziano / Demi, Libertario / Inchingolo, Riccardo / Smargiassi, Andrea / Soldati, Gino

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2020  Volume 40, Issue 10, Page(s) 2263–2264

    Language English
    Publishing date 2020-12-22
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.15602
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  8. Article ; Online: Lung Ultrasound Signs: The Beginning. Part 3-An Accademia di Ecografia Toracica Comprehensive Review on Ultrasonographic Signs and Real Needs.

    Inchingolo, Riccardo / Zanforlin, Alessandro / Buonsenso, Danilo / Perrone, Tiziano / Torri, Elena / Limoli, Giuseppe / Mossolani, Elisa Eleonora / Tursi, Francesco / Soldati, Gino / Marchetti, Giampietro / Carlucci, Paolo / Radovanovic, Dejan / Lohmeyer, Franziska Michaela / Smargiassi, Andrea

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2024  Volume 43, Issue 4, Page(s) 629–641

    Abstract: Over the last 20 years, scientific literature and interest on chest/lung ultrasound (LUS) have exponentially increased. Interpreting mixed-anatomical and artifactual-pictures determined the need of a proposal of a new nomenclature of artifacts and signs ... ...

    Abstract Over the last 20 years, scientific literature and interest on chest/lung ultrasound (LUS) have exponentially increased. Interpreting mixed-anatomical and artifactual-pictures determined the need of a proposal of a new nomenclature of artifacts and signs to simplify learning, spread, and implementation of this technique. The aim of this review is to collect and analyze different signs and artifacts reported in the history of chest ultrasound regarding normal lung, pleural pathologies, and lung consolidations. By reviewing the possible physical and anatomical interpretation of these artifacts and signs reported in the literature, this work aims to present the AdET (Accademia di Ecografia Toracica) proposal of nomenclature and to bring order between published studies.
    MeSH term(s) Humans ; Lung/diagnostic imaging ; Lung Diseases/diagnostic imaging ; Thorax ; Ultrasonography/methods ; Artifacts
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16397
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  9. Article ; Online: Reply.

    Soldati, Gino / Smargiassi, Andrea / Inchingolo, Riccardo / Torri, Elena / Demi, Libertario

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2020  Volume 40, Issue 1, Page(s) 213–214

    MeSH term(s) COVID-19 ; Health Personnel ; Humans ; Lung ; Reference Standards ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-08
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.15388
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  10. Article ; Online: Reply: on CEUS Applicability to COVID-19 Patients.

    Soldati, Gino / Giannasi, Gianfranco / Inchingolo, Riccardo / Smargiassi, Andrea / Demi, Libertario

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2020  Volume 40, Issue 4, Page(s) 867–868

    MeSH term(s) COVID-19 ; Contrast Media ; Humans ; Pulmonary Circulation ; SARS-CoV-2 ; Ultrasonography
    Chemical Substances Contrast Media
    Keywords covid19
    Language English
    Publishing date 2020-08-31
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.15450
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