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  1. Article ; Online: Role of Magnetic Resonance Imaging in Transcatheter Structural Heart Disease Interventions.

    Proffitt, Elizabeth K / Kaproth-Joslin, Katherine / Chaturvedi, Abhishek / Hobbs, Susan K

    Seminars in roentgenology

    2023  Volume 59, Issue 1, Page(s) 20–31

    MeSH term(s) Humans ; Heart Diseases/diagnostic imaging ; Heart Diseases/therapy ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80310-8
    ISSN 1558-4658 ; 0037-198X
    ISSN (online) 1558-4658
    ISSN 0037-198X
    DOI 10.1053/j.ro.2023.12.003
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  2. Article ; Online: Multimodality Imaging in Planning of Complex TAVR Procedures.

    Kalisz, Kevin / Moore, Alastair / Chaturvedi, Abhishek / Rajiah, Prabhakar Shantha

    Seminars in roentgenology

    2023  Volume 59, Issue 1, Page(s) 57–66

    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/methods ; Multimodal Imaging/methods ; Treatment Outcome ; Risk Factors
    Language English
    Publishing date 2023-11-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80310-8
    ISSN 1558-4658 ; 0037-198X
    ISSN (online) 1558-4658
    ISSN 0037-198X
    DOI 10.1053/j.ro.2023.10.002
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  3. Article ; Online: Mitral valve remodeling in the development of obstructive hypertrophic cardiomyopathy.

    Moroni, Francesco / Chaturvedi, Abhishek / Jafree, Ehsan / Gertz, Zachary M

    Indian heart journal

    2023  Volume 75, Issue 4, Page(s) 308–310

    Abstract: Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral ... ...

    Abstract Approximately 2/3 of patients with hypertrophic cardiomyopathy (HCM) have significant left ventricular outflow tract obstruction (LVOTO), which is caused by the interaction mitral valve apparatus and the hypertrophied septum. The contribution of mitral valve remodeling to the development of obstruction over time has never been described. We analyzed retrospectively 40 patients with HCM and no baseline obstruction followed up for a median of 2179 days. At follow up, 13 patients developed significant LVOTO. Patients who developed LVOTO had longer posterior leaflets and longer anterior leaflet residual length.
    MeSH term(s) Humans ; Mitral Valve/diagnostic imaging ; Retrospective Studies ; Ventricular Outflow Obstruction/diagnosis ; Ventricular Outflow Obstruction/etiology ; Cardiomyopathy, Hypertrophic/diagnosis ; Ventricular Outflow Obstruction, Left
    Language English
    Publishing date 2023-06-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 604366-5
    ISSN 2213-3763 ; 0019-4832
    ISSN (online) 2213-3763
    ISSN 0019-4832
    DOI 10.1016/j.ihj.2023.06.007
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    Zs.A 616: Show issues Location:
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  4. Article ; Online: Advancing posaconazole quantification analysis with a new reverse-phase HPLC method in its bulk and marketed dosage form.

    Rama, Annamalai / Govindan, Induja / Hebbar, Srinivas / Chaturvedi, Abhishek / Rani, Usha / Naha, Anup

    F1000Research

    2023  Volume 12, Page(s) 468

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Chromatography, High Pressure Liquid/methods ; Tablets ; Triazoles/analysis ; Antifungal Agents
    Chemical Substances posaconazole (6TK1G07BHZ) ; Tablets ; Triazoles ; Antifungal Agents
    Language English
    Publishing date 2023-06-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.132841.2
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  5. Article ; Online: Correction to: 4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson's Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation.

    Tiwari, Shubhangini / Gupta, Parul / Singh, Abhishek / Chaturvedi, Swati / Wahajuddin, M / Mishra, Amit / Singh, Sarika

    Neurochemical research

    2023  Volume 48, Issue 10, Page(s) 3251–3252

    Language English
    Publishing date 2023-07-05
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-023-03975-z
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  6. Article: Optimizing low contrast volume thoracic CT angiography: From the basics to the advanced.

    Kaproth-Joslin, Katherine / Hobbs, Susan / Rajiah, Prabhakar / Chaturvedi, Apeksha / Chaturvedi, Abhishek

    Journal of clinical imaging science

    2022  Volume 12, Page(s) 41

    Abstract: Contrast-enhanced CT angiography (CTA) is a widely used, noninvasive imaging technique for evaluating cardiovascular structures. Contrast-induced nephrotoxicity is a concern in renal disease; however, the true nephrotoxic potential of iodinated contrast ... ...

    Abstract Contrast-enhanced CT angiography (CTA) is a widely used, noninvasive imaging technique for evaluating cardiovascular structures. Contrast-induced nephrotoxicity is a concern in renal disease; however, the true nephrotoxic potential of iodinated contrast media (CM) is unknown. If a renal impaired patient requires CTA, it is important to protect the kidneys from further harm by reducing total iodinated CM volume while still obtaining diagnostic quality imaging. These same reduced volume CM techniques can also be applied to nonrenal impaired patients in times of CM shortage. This educational review discusses several modifications to CTA that can be adapted to both conventional 64-slice and the newer generation CT scanners which enable subsecond acquisition with a reduced CM volume technique. Such modifications include hardware and software adjustments and changes to both the volume and flow rate of administered CM, with the goal to reduce the dose of CM without compromising diagnostic yield.
    Language English
    Publishing date 2022-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2601233-9
    ISSN 2156-5597 ; 2156-7514
    ISSN (online) 2156-5597
    ISSN 2156-7514
    DOI 10.25259/JCIS_51_2022
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  7. Article ; Online: Patient-directed follow-up for the clinical scaphoid fracture.

    Chaturvedi, Abhishek / Russell, Heather / Farrugia, Matthew / Roger, Mark / Putti, Amit / Jenkins, Paul J / Feltbower, Stephen

    Bone & joint open

    2024  Volume 5, Issue 2, Page(s) 117–122

    Abstract: Aims: Occult (clinical) injuries represent 15% of all scaphoid fractures, posing significant challenges to the clinician. MRI has been suggested as the gold standard for diagnosis, but remains expensive, time-consuming, and is in high demand. ... ...

    Abstract Aims: Occult (clinical) injuries represent 15% of all scaphoid fractures, posing significant challenges to the clinician. MRI has been suggested as the gold standard for diagnosis, but remains expensive, time-consuming, and is in high demand. Conventional management with immobilization and serial radiography typically results in multiple follow-up attendances to clinic, radiation exposure, and delays return to work. Suboptimal management can result in significant disability and, frequently, litigation.
    Methods: We present a service evaluation report following the introduction of a quality-improvement themed, streamlined, clinical scaphoid pathway. Patients are offered a removable wrist splint with verbal and written instructions to remove it two weeks following injury, for self-assessment. The persistence of pain is the patient's guide to 'opt-in' and to self-refer for a follow-up appointment with a senior emergency physician. On confirmation of ongoing signs of clinical scaphoid injury, an urgent outpatient 'fast'-wrist protocol MRI scan is ordered, with instructions to maintain wrist immobilization. Patients with positive scan results are referred for specialist orthopaedic assessment via a virtual fracture clinic.
    Results: From February 2018 to January 2019, there were 442 patients diagnosed as clinical scaphoid fractures. 122 patients (28%) self-referred back to the emergency department at two weeks. Following clinical review, 53 patients were discharged; MRI was booked for 69 patients (16%). Overall, six patients (< 2% of total; 10% of those scanned) had positive scans for a scaphoid fracture. There were no known missed fractures, long-term non-unions or malunions resulting from this pathway. Costs were saved by avoiding face-to-face clinical review and MRI scanning.
    Conclusion: A patient-focused opt-in approach is safe and effective to managing the suspected occult (clinical) scaphoid fracture.
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Journal Article
    ISSN 2633-1462
    ISSN (online) 2633-1462
    DOI 10.1302/2633-1462.52.BJO-2023-0119.R1
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  8. Article: Corrigendum to "Possible Role for Bacteriophages in the Treatment of SARS-CoV-2 Infection".

    Mishra, Vijaya Nath / Nidhi, Kumari / Pathak, Abhishek / Chaturvedi, Rajnish Kumar / Gupta, Arun Kumar / Chaurasia, Rameshwar Nath

    International journal of microbiology

    2022  Volume 2022, Page(s) 9857582

    Abstract: This corrects the article DOI: 10.1155/2020/8844963.]. ...

    Abstract [This corrects the article DOI: 10.1155/2020/8844963.].
    Language English
    Publishing date 2022-04-07
    Publishing country Egypt
    Document type Published Erratum
    ZDB-ID 2467270-1
    ISSN 1687-9198 ; 1687-918X
    ISSN (online) 1687-9198
    ISSN 1687-918X
    DOI 10.1155/2022/9857582
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  9. Article ; Online: Acute Kidney Injury in Patients Undergoing Both Right and Left Heart Catheterization with Coronary Angiography Vs Right Heart Catheterization Only.

    Min, Annette / Roy, Sumon / Chaturvedi, Abhishek / Choxi, Ravi / Wasilewski, Melissa / Arora, Pradeep / Perera, Robert A / Jovin, Ion S

    The American journal of medicine

    2024  Volume 137, Issue 5, Page(s) 442–448

    Abstract: Background: Recent studies have challenged the reported causal association between acute kidney injury and iodinated contrast administration, ascribing some cases to changes in renal function that are independent of contrast administration.: Methods: ...

    Abstract Background: Recent studies have challenged the reported causal association between acute kidney injury and iodinated contrast administration, ascribing some cases to changes in renal function that are independent of contrast administration.
    Methods: We studied 1779 consecutive patients undergoing right heart catheterization (RHC) at a Veterans Administration Medical Center. We compared the incidence of acute kidney injury and of nephropathy at 3 months in veterans undergoing right and left heart catheterization and coronary angiography (R&LHC) to the incidence of acute kidney injury and of nephropathy at 3 months in patients undergoing RHC only.
    Results: The incidence of acute kidney injury at 3 days was 47 (9.7%) in the R&LHC group and 58 (9.6%) in the RHC group (P = .99). The incidence of nephropathy at 3 months was 115 (17%) in the L&RHC group and 141 (19.2%) in the RHC group (P = 0.31). In a propensity score-paired analysis of 782 patients and after adjustment for baseline characteristics, the odds ratio for acute kidney injury at 3 days among patients undergoing R&LHC was 1.25 (95% confidence interval, 0.65-2.42; P = .50), and the odds ratio for nephropathy at 3 months was 0.69 (95% confidence interval, 0.46-1.04; P = .08).
    Conclusion: The incidence of changes in creatinine consistent with acute kidney injury at 3 days and of nephropathy at 3 months was not significantly different in patients undergoing R&LHC compared with patients undergoing RHC only. This supports the thesis that not all changes in creatinine after procedures involving administration of contrast are caused by the contrast.
    MeSH term(s) Humans ; Acute Kidney Injury/epidemiology ; Acute Kidney Injury/etiology ; Cardiac Catheterization/adverse effects ; Male ; Coronary Angiography/adverse effects ; Coronary Angiography/methods ; Female ; Aged ; Middle Aged ; Contrast Media/adverse effects ; Incidence ; Retrospective Studies
    Chemical Substances Contrast Media
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article ; Comparative Study
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2024.01.011
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  10. Article ; Online: Decreased expression of CD200 on peripheral blood leukocytes in alcohol dependence.

    Chaturvedi, Abhishek / Rao, Guruprasad / Praharaj, Samir Kumar / Guruprasad, Kanive Parashiva / Pais, Vivek / Sadacharan, Chakravarthy Marx

    Alcohol (Fayetteville, N.Y.)

    2023  Volume 113, Page(s) 21–25

    Abstract: Chronic alcohol use induces innate immune genes, which activate the innate immune system. Neuroimmune regulatory proteins [e.g., Cluster of Differentiation 200 (CD200)] are immune response regulators and are involved in balancing the immune response. ... ...

    Abstract Chronic alcohol use induces innate immune genes, which activate the innate immune system. Neuroimmune regulatory proteins [e.g., Cluster of Differentiation 200 (CD200)] are immune response regulators and are involved in balancing the immune response. This study aimed to investigate the expression of CD200 on the surface of peripheral blood leukocytes in patients with alcohol use disorder and compare them with controls. Fifty male patients with alcohol use disorder were included in the study. A baseline assessment was done, and alcohol use history, craving, and withdrawal scores were collected. A 2-mL venous blood sample was collected from cases and controls for immunophenotyping of CD200. The control group consisted of 50 participants with similar socio-economic backgrounds. The cellular expression of CD200 on total leukocytes (median ± IQR) [39.94 (28.85, 50.01)] in cases was significantly lower compared to controls [45.07 (37.70, 51.69)] (U = 896, p = 0.015). Expression of CD200 on lymphocytes in cases was negatively correlated with years of heavy drinking and this was statistically significant (r = -0.321, p = 0.023). The study indicates that cellular expression of CD200 on the surface of peripheral blood leukocytes is reduced in alcohol-dependent patients. This reduction can contribute to exaggerated immune activity, release of pro-inflammatory cytokines, chronic microglial activation, neuroinflammation, and neurodegeneration in alcohol dependence.
    MeSH term(s) Humans ; Male ; Alcoholism ; Antigens, CD/metabolism ; Leukocytes/metabolism ; Cytokines/metabolism
    Chemical Substances Antigens, CD ; Cytokines
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605912-0
    ISSN 1873-6823 ; 0741-8329
    ISSN (online) 1873-6823
    ISSN 0741-8329
    DOI 10.1016/j.alcohol.2023.08.003
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