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  1. Book: Underwood's pathology

    Underwood, James C. E. / Cross, Simon S.

    a clinical approach

    2019  

    Title variant Pathology
    Author's details edited by Simon Cross
    Keywords Pathology
    Language English
    Size xviii, 754 Seiten, Illustrationen, 28 cm
    Edition Seventh edition
    Publisher CHurchill Livingstone Elsevier
    Publishing place Edinburgh
    Publishing country Great Britain
    Document type Book
    Note Zugang zur Online-Ausgabe über Code
    HBZ-ID HT019797890
    ISBN 978-0-7020-7212-3 ; 9780702072109 ; 0-7020-7212-5 ; 0702072109
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Enterococcus faecalis

    Nye, Clemency / Maxwell, Alice / Hughes, Harriet / Underwood, Jonathan

    Clinical infection in practice

    2024  Volume 21, Page(s) 100336

    Abstract: Introduction: Enterococcus faecalis: Methods: All blood cultures in patients over 18 which were positive for : Results: The rate of patients with : Discussion: The lower reported rate of IE in our cohort may be explained by higher proportion of ...

    Abstract Introduction: Enterococcus faecalis
    Methods: All blood cultures in patients over 18 which were positive for
    Results: The rate of patients with
    Discussion: The lower reported rate of IE in our cohort may be explained by higher proportion of CVC related infections. However, given the low rates of echocardiography and poor correlation of echocardiography use with IE risk factors, it is likely that cases of IE are being missed, particularly in those with multiple risk factors. Despite this, there was no difference in one-year survival between those diagnosed with IE vs without IE. We have delivered education sessions and introduced a multidisciplinary team meeting to discuss infective endocarditis cases to address these issues.
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ISSN 2590-1702
    ISSN (online) 2590-1702
    DOI 10.1016/j.clinpr.2023.100336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Gaps in Treatment-Related Fears of Patients With Low-Risk Thyroid Cancer-The Gender Divide.

    Jackson, Anee Sophia / Underwood, Hunter J / Pitt, Susan C

    JAMA otolaryngology-- head & neck surgery

    2023  Volume 149, Issue 9, Page(s) 810–811

    MeSH term(s) Humans ; Fear ; Thyroid Neoplasms/therapy ; Risk
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2023.1639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Underwood's pathology

    Cross, Simon S. / Underwood, James C. E. / Britton, Robert

    a clinical approach

    (Student Consult)

    2013  

    Title variant Pathology
    Author's details ed. by Simon S. Cross. Ill. and chapter icons by Robert Britton
    Series title Student Consult
    Keywords Pathology
    Language English
    Size XVIII, 769 S. : zahlr. Ill.
    Edition 6. ed.
    Publisher Churchill Livingstone Elsevier
    Publishing place Edinburgh u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    Accompanying material Zugang zur Internetausgabe über Code
    Old title Frühere Aufl. u.d.T. General and systematic pathology
    HBZ-ID HT017609903
    ISBN 978-0-7020-4672-8 ; 978-0-7020-4673-5 ; 0-7020-4672-8 ; 0-7020-4673-6
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Patient Characteristics and Variables Influencing Acute Medical Flow.

    Wood, C H / Underwood, J / Davies, C / Taylor, P N

    Acute medicine

    2023  Volume 21, Issue 4, Page(s) 168–175

    Abstract: Waiting times are the most widely used indicator of patient flow. This project aims to analyse 24-hour variation in referrals and waiting times for patients referred to the Acute Medical Service (AMS). A retrospective cohort study was conducted at the ... ...

    Abstract Waiting times are the most widely used indicator of patient flow. This project aims to analyse 24-hour variation in referrals and waiting times for patients referred to the Acute Medical Service (AMS). A retrospective cohort study was conducted at the AMS of Wales' largest hospital. Collected data included patient characteristics, referral times, waiting times and adherence to Clinical Quality Indicators (CQIs). Peak referral times were found between 11:00-19:00. Peak waiting times occurred between 17:00-01:00, which was longer on weekdays in comparison to weekends. Referrals between 17:00-21:00 had the longest waiting times with > 40% of patients failing both junior and senior CQIs. Mean and median age and NEWS were higher between 17:00-09:00. Weekday evening and nights are problematic for acute medical patient flow. Interventions, including workforce, should be targeted towards these findings.
    MeSH term(s) Humans ; Retrospective Studies ; Referral and Consultation ; Hospitals ; Data Collection
    Language English
    Publishing date 2023-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2213243-0
    ISSN 1747-4892 ; 1747-4884 ; 1476-5063
    ISSN (online) 1747-4892
    ISSN 1747-4884 ; 1476-5063
    DOI 10.52964/AMJA.0920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: General and systematic pathology

    Underwood, James C. E.

    2009  

    Title variant Pathology
    Author's details ed. by J. C. E. Underwood
    Keywords Pathology ; Physiology, Pathological
    Subject code 616.07
    Language English
    Size XI, 857 S. : zahlr. Ill., graph. Darst., 28cm
    Edition 5. ed.
    Publisher Churchill Livingstone Elsevier
    Publishing place Edinburgh u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index. - Previous ed.: 2004. - Includes Internet access
    Accompanying material Zugang zur Internetausgabe über Code
    New title Spätere Aufl. u.d.T. Underwood's pathology
    HBZ-ID HT015959020
    ISBN 978-0-443-06888-1 ; 0-443-06888-7
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: N

    Underwood, Steven J / Douglas, Christopher J

    Organic letters

    2022  Volume 25, Issue 1, Page(s) 146–151

    Abstract: ... removable directing group being ideal. Herein we disclose our method for rhodium-catalyzed C-O bond ...

    Abstract Directing groups are a common strategy to target traditionally inert bonds, with an easily removable directing group being ideal. Herein we disclose our method for rhodium-catalyzed C-O bond functionalization of
    MeSH term(s) Catalysis ; Rhodium/chemistry ; Pyridines/chemistry
    Chemical Substances Rhodium (DMK383DSAC) ; Pyridines
    Language English
    Publishing date 2022-12-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.2c03961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Review: Targeting EZH2 in neuroblastoma.

    Gao, Jinhui / Fosbrook, Claire / Gibson, Jane / Underwood, Timothy J / Gray, Juliet C / Walters, Zoë S

    Cancer treatment reviews

    2023  Volume 119, Page(s) 102600

    Abstract: Neuroblastoma is one of the commonest extra-cranial pediatric tumors, and accounts for over 15% of all childhood cancer mortality. Risk stratification for children with neuroblastoma is based on age, stage, histology, and tumor cytogenetics. The majority ...

    Abstract Neuroblastoma is one of the commonest extra-cranial pediatric tumors, and accounts for over 15% of all childhood cancer mortality. Risk stratification for children with neuroblastoma is based on age, stage, histology, and tumor cytogenetics. The majority of patients are considered to have high-risk neuroblastoma, for which the long-term survival is less than 50%. Current treatments combine surgical resection, chemotherapy, stem cell transplantation, radiotherapy, anti-GD2 based immunotherapy as well as the differentiating agent isotretinoin. Despite the intensive multimodal therapies applied, there are high relapse rates, and recurrent disease is often resistant to further therapy. Enhancer of Zeste Homolog 2 (EZH2), a catalytic subunit of Polycomb Repressive Complex 2 (PRC2), is a histone methyltransferase that represses transcription through trimethylation of lysine residue K27 on histone H3 (H3K27me3). It is responsible for epigenetic repression of transcription, making EZH2 an essential regulator for cell differentiation. Overexpression of EZH2 has been shown to promote tumorigenesis, cancer cell proliferation and prevent tumor cells from differentiating in a number of cancers. Therefore, research has been ongoing for the past decade, developing treatments that target EZH2 in neuroblastoma. This review summarises the role of EZH2 in neuroblastoma and evaluates the latest research findings on the therapeutic potential of targeting EZH2 in the treatment of neuroblastoma.
    MeSH term(s) Humans ; Child ; Enhancer of Zeste Homolog 2 Protein/genetics ; Cell Line, Tumor ; Neoplasm Recurrence, Local ; Polycomb Repressive Complex 2 ; Neuroblastoma/genetics ; Neuroblastoma/therapy ; Neuroblastoma/pathology
    Chemical Substances Enhancer of Zeste Homolog 2 Protein (EC 2.1.1.43) ; Polycomb Repressive Complex 2 (EC 2.1.1.43) ; EZH2 protein, human (EC 2.1.1.43)
    Language English
    Publishing date 2023-07-13
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 125102-8
    ISSN 1532-1967 ; 0305-7372
    ISSN (online) 1532-1967
    ISSN 0305-7372
    DOI 10.1016/j.ctrv.2023.102600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Reply: Cognitive behavioural therapy sessions approach ineffective for anxiety and depression in COPD: is the door closed for good?

    Taylor, Stephanie J C / Sohanpal, Ratna / Steed, Liz / Marshall, Karen / Kelly, Moira J / Underwood, Martin / White, Patrick / Pinnock, Hilary

    The European respiratory journal

    2024  Volume 63, Issue 1

    MeSH term(s) Humans ; Depression/therapy ; Depression/psychology ; Psychosocial Intervention ; Anxiety/therapy ; Anxiety/psychology ; Cognitive Behavioral Therapy ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/therapy ; Pulmonary Disease, Chronic Obstructive/psychology
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.02149-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Effects of Zilpaterol Hydrochloride Supplementation on Growth Performance, Carcass Characteristics and Meat Quality for Steers Differing in Breed Type.

    Fulton, Jesse O / Block, Janna J / Underwood, Keith R / Zuelly, Stacy M S / Olson, Kenneth C / Blair, Amanda D

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 4

    Abstract: To determine the effects of zilpaterol hydrochloride (ZH) on growth performance, carcass characteristics and meat quality for steers differing in breed type, steers with British (B; ...

    Abstract To determine the effects of zilpaterol hydrochloride (ZH) on growth performance, carcass characteristics and meat quality for steers differing in breed type, steers with British (B;
    Language English
    Publishing date 2024-02-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14040607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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