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Article ; Online: Possible association of papillary muscle hypertrophy with the genesis of J-waves.

Ebata, Yuki / Nakagawa, Mikiko / Kondo, Hidekazu / Ezaki, Kaori / Miyazaki, Hiroko / Shinohara, Tetsuji / Teshima, Yasushi / Yufu, Kunio / Takahashi, Naohiko

Journal of cardiology

2019 Volume 75, Issue 1, Page(s) 90–96

Abstract: Background: Although J-waves have been known to be associated with vulnerability ... arrhythmias. However, the relationship between PM hypertrophy and J-waves has not been investigated ... Objective: To investigate the electrocardiographic characteristics, including the J-waves, in patients ...

Abstract	Background: Although J-waves have been known to be associated with vulnerability to ventricular fibrillation, their electrophysiologic mechanism remains to be elucidated. The papillary muscles (PMs) of the left ventricle (LV) have been recognized as the target site of radiofrequency ablation for ventricular arrhythmias. However, the relationship between PM hypertrophy and J-waves has not been investigated. Objective: To investigate the electrocardiographic characteristics, including the J-waves, in patients with solitary PM hypertrophy. Methods: We studied 101 patients with PM hypertrophy without LV hypertrophy (PMH group) and 159 age- and sex-matched control subjects (control group). The parameters of the 12-lead electrocardiogram and the echocardiogram were compared between the two groups. Results: Compared with the control group, the PMH group had significantly higher incidence (15% vs. 33%, p=0.001) and amplitude (0.17±0.06mV vs. 0.28±0.17mV, p<0.01) of J-waves; significantly longer QRS, QTc, and JTc intervals (p=0.0001, p<0.0001, and p<0.05, respectively); significantly greater Sokolow-Lyon index (p<0.001); and significantly greater LV wall thickness and LV mass index (p<0.0001 for each). Multivariate logistic regression analysis showed that only the PM hypertrophy was an independent predictor of the presence of J-waves. Conclusion: PM hypertrophy was related to the genesis of J-waves.
MeSH term(s)	Aged ; Aged, 80 and over ; Echocardiography ; Electrocardiography ; Female ; Humans ; Hypertrophy, Left Ventricular/diagnostic imaging ; Hypertrophy, Left Ventricular/pathology ; Hypertrophy, Left Ventricular/physiopathology ; Male ; Middle Aged ; Papillary Muscles/diagnostic imaging ; Papillary Muscles/pathology ; Papillary Muscles/physiopathology
Language	English
Publishing date	2019-07-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	639364-0
ISSN	1876-4738 ; 0386-2887 ; 0914-5087
ISSN (online)	1876-4738
ISSN	0386-2887 ; 0914-5087
DOI	10.1016/j.jjcc.2019.07.001
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Zs.A 1794: Show issues

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Article ; Online: Effect of ECG filter settings on J-waves.

Nakagawa, Mikiko / Tsunemitsu, Chie / Katoh, Sayo / Kamiyama, Yukari / Sano, Nario / Ezaki, Kaori / Miyazaki, Hiroko / Teshima, Yasushi / Yufu, Kunio / Takahashi, Naohiko / Saikawa, Tetsunori

Journal of electrocardiology

2014 Volume 47, Issue 1, Page(s) 7–11

Abstract: Background: While J-waves were observed in healthy populations, variations in their reported ... who manifested J-waves on ECGs acquired with a 150-Hz low-pass filter. We then studied the J-waves on individual ... recorded with the 25-Hz filter. The amplitude of J-waves was significantly lower with 25- and 35-Hz than 75 ...

Abstract	Background: While J-waves were observed in healthy populations, variations in their reported incidence may be partly explicable by the ECG filter setting. Methods: We obtained resting 12-lead ECG recordings in 665 consecutive patients and enrolled 112 (56 men, 56 women, mean age 59.3±16.1years) who manifested J-waves on ECGs acquired with a 150-Hz low-pass filter. We then studied the J-waves on individual ECGs to look for morphological changes when 25-, 35-, 75-, 100-, and 150Hz filters were used. Results: The notching observed with the 150-Hz filter changed to slurring (42%) or was eliminated (28%) with the 25-Hz filter. Similarly, the slurring seen with the 150-Hz filter was eliminated on 71% of ECGs recorded with the 25-Hz filter. The amplitude of J-waves was significantly lower with 25- and 35-Hz than 75-, 100-, and 150-Hz filters (p<0.0001). Conclusions: The ECG filter setting significantly affects the J-wave morphology.
MeSH term(s)	Algorithms ; Artifacts ; Diagnosis, Computer-Assisted/methods ; Electrocardiography/methods ; Female ; Heart Conduction System/physiology ; Heart Rate/physiology ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Sensitivity and Specificity ; Signal Processing, Computer-Assisted
Language	English
Publishing date	2014-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	410286-1
ISSN	1532-8430 ; 0022-0736
ISSN (online)	1532-8430
ISSN	0022-0736
DOI	10.1016/j.jelectrocard.2013.10.001
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Zs.A 701: Show issues

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Article ; Online: False tendons may be associated with the genesis of J-waves: prospective study in young healthy male.

Nakagawa, Mikiko / Ezaki, Kaori / Miyazaki, Hiroko / Ebata, Yuki / Shinohara, Tetsuji / Teshima, Yasushi / Yufu, Kunio / Takahashi, Naohiko / Saikawa, Tetsunori

International journal of cardiology

2014 Volume 172, Issue 2, Page(s) 428–433

Abstract: Background: Recent studies showed that J-waves are associated with vulnerability ... to ventricular fibrillation. Recently we reported the association between false tendons (FTs) and J-waves ... longitudinal type), type 2 (diagonal type), and type 3 (transverse type). J-waves were defined as terminal QRS ...

Abstract	Background: Recent studies showed that J-waves are associated with vulnerability to ventricular fibrillation. Recently we reported the association between false tendons (FTs) and J-waves in a retrospective study. Methods and results: We prospectively studied 50 young healthy men (mean age 24.6±2.7 years). FTs were detected echocardiographically and classified based on their points of attachment as type 1 (longitudinal type), type 2 (diagonal type), and type 3 (transverse type). J-waves were defined as terminal QRS notching or slurring with ≥0.1 mV. The filtered QRS duration (fQRSd), RMS40, and LAS40 were measured on signal-averaged ECGs. FTs were detected in 37 of the 50 subjects (74%). The incidence of J-waves was significantly higher in subjects with type 1 or type 2 FTs than those with no- or type 3 FTs (61% vs. 26%, p<0.05). The leads with J-waves were closely associated with the location of the FT. While no late potential was recorded in any study subjects, fQRSd and LAS40 were significantly longer in subjects with type 1 or type 2 FTs (p<0.05). Univariate and multivariate logistic regression analysis revealed that only the existence of FTs (type 1 or 2) was an independent predictor of the presence of J-waves. Conclusions: Our results suggest that FTs were related to the genesis of J-waves with conduction delay.
MeSH term(s)	Arrhythmias, Cardiac/etiology ; Arrhythmias, Cardiac/physiopathology ; Echocardiography ; Electrocardiography ; Heart Conduction System/physiopathology ; Heart Ventricles/abnormalities ; Humans ; Male ; Prospective Studies ; Young Adult
Language	English
Publishing date	2014-03-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2014.01.101
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Zs.A 1673: Show issues

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Article ; Online: Electrocardiographic characteristics of patients with false tendon: possible association of false tendon with J waves.

Nakagawa, Mikiko / Ezaki, Kaori / Miyazaki, Hiroko / Wakisaka, Osamu / Shinohara, Tetsuji / Teshima, Yasushi / Yufu, Kunio / Takahashi, Naohiko / Saikawa, Tetsunori

Heart rhythm

2012 Volume 9, Issue 5, Page(s) 782–788

Abstract: ... of ventricular arrhythmias. The presence of J waves is associated with vulnerability to ventricular arrhythmias ... however, the mechanisms underlying the manifestation of J waves remain to be elucidated.: Objective: To investigate ... the electrocardiographic characteristics, including the presence of J waves, in patients with FTs.: Methods: We studied ...

Abstract	Background: The false tendons (FTs) are fibromuscular bands that transverse the left ventricular cavity and often contain conduction tissue, suggesting that FTs may contribute to the occurrence of ventricular arrhythmias. The presence of J waves is associated with vulnerability to ventricular arrhythmias; however, the mechanisms underlying the manifestation of J waves remain to be elucidated. Objective: To investigate the electrocardiographic characteristics, including the presence of J waves, in patients with FTs. Methods: We studied 44 patients with distinct FTs detected by echocardiography (FT group) and 88 age- and sex-matched healthy subjects without FTs (control group). The PQ, QRS, JT, QT, corrected JT, and corrected QT intervals were automatically measured on surface 12-lead electrocardiograms, and the presence or absence of J waves was also determined. J waves were defined as terminal QRS notching or slurring. FTs were classified according to their points of attachment as type 1 (longitudinal, 52%), type 2 (diagonal, 25%), type 3 (transverse, 16%), and type 4 (weblike, 7%). Results: QRS and corrected QT intervals were significantly longer in the FT group than in the control group (P <.005 and P <.05, respectively). The incidence of J waves was significantly higher in the FT group (64%) than in the control group (19%) (P <.0001). J waves were more prevalent in type 1 (78%) and type 2 (73%) than in type 3 (14%) and 4 FTs (33%) (P <0.05) and in patients with thick FTs (≥ 2 mm) than with thinner FTs (<2 mm) (71% vs 33%; P <.05). The J-wave location differed according to the FT type. Conclusions: Our results suggest that FTs may carry a certain role to the genesis of J waves.
MeSH term(s)	Arrhythmias, Cardiac/physiopathology ; Electrocardiography ; Female ; Heart Conduction System/physiopathology ; Heart Ventricles/abnormalities ; Heart Ventricles/diagnostic imaging ; Humans ; Male ; Ultrasonography
Language	English
Publishing date	2012-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2229357-7
ISSN	1556-3871 ; 1547-5271
ISSN (online)	1556-3871
ISSN	1547-5271
DOI	10.1016/j.hrthm.2011.12.022
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Zs.A 6278: Show issues

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Article ; Online: Comparison of autonomic J-wave modulation in patients with idiopathic ventricular fibrillation and control subjects.

Miyazaki, Hiroko / Nakagawa, Mikiko / Shin, Yukie / Wakisaka, Osamu / Shinohara, Tetsuji / Ezaki, Kaori / Teshima, Yasushi / Yufu, Kunio / Takahashi, Naohiko / Hara, Masahide / Saikawa, Tetsunori

Circulation journal : official journal of the Japanese Circulation Society

2012 Volume 77, Issue 2, Page(s) 330–337

Abstract: Background: Although J-waves are seen in both patients with idiopathic ventricular fibrillation ... IVF) and the general population, their genesis remains unclear. To assess the relationship between J ... waves and autonomic tone we investigated the circadian variation of J-waves in individuals with and ...

Abstract	Background: Although J-waves are seen in both patients with idiopathic ventricular fibrillation (IVF) and the general population, their genesis remains unclear. To assess the relationship between J-waves and autonomic tone we investigated the circadian variation of J-waves in individuals with and without IVF. Methods and results: In study 1, we obtained resting 12-lead ECG and Holter ECG recordings in 258 individuals undergoing screening for heart disease. In 60 of these subjects (23.3%), we detected J-waves on Holter ECGs; 40 of them (66.7%) had shown no J-waves on 12-lead ECGs. In study 2, we measured the J-wave amplitude, heart rate (HR), and HR variability [high frequency (HF) and the ratio of low- to high-frequency (LF/HF)] on Holter ECGs recorded in 5 patients with IVF and 20 control subjects who had manifested J-waves. The J-wave amplitude increased at night and decreased during the day in both groups; it was significantly higher in the IVF patients (P<0.0001). In both groups, the J-wave amplitude showed a significant negative correlation with HR and LF/HF and a significant positive correlation with HF. The slope of the J/HR and J/(LF/HF) relationship was significantly steeper in the IVF patients. Conclusions: The J-wave amplitude was more significantly influenced by the autonomic balance in IVF patients than in the controls. Autonomic J-wave modulation may yield important information on the genesis of J-waves.
MeSH term(s)	Adult ; Autonomic Nervous System/physiology ; Circadian Rhythm/physiology ; Electrocardiography, Ambulatory ; Female ; Heart Rate/physiology ; Humans ; Incidence ; Male ; Middle Aged ; Myocardial Ischemia/diagnosis ; Myocardial Ischemia/epidemiology ; Myocardial Ischemia/physiopathology ; Tachycardia, Supraventricular/diagnosis ; Tachycardia, Supraventricular/epidemiology ; Tachycardia, Supraventricular/physiopathology ; Ventricular Fibrillation/diagnosis ; Ventricular Fibrillation/epidemiology ; Ventricular Fibrillation/physiopathology
Language	English
Publishing date	2012-10-23
Publishing country	Japan
Document type	Comparative Study ; Journal Article
ZDB-ID	2068090-9
ISSN	1347-4820 ; 1346-9843
ISSN (online)	1347-4820
ISSN	1346-9843
DOI	10.1253/circj.cj-12-0749
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Article: Comprehensive assessments of pulmonary circulation in children with pulmonary hypertension associated with congenital heart disease.

Muneuchi, Jun / Ezaki, Hiroki / Sugitani, Yuichiro / Watanabe, Mamie

Frontiers in pediatrics

2022 Volume 10, Page(s) 1011631

Abstract: Pulmonary hypertension associated with congenital heart disease (CHD-PH) encompasses different conditions confounded by the left-to-right shunt, left heart obstruction, ventricular dysfunction, hypoxia due to airway obstruction, dysplasia/hypoplasia of ... ...

Abstract	Pulmonary hypertension associated with congenital heart disease (CHD-PH) encompasses different conditions confounded by the left-to-right shunt, left heart obstruction, ventricular dysfunction, hypoxia due to airway obstruction, dysplasia/hypoplasia of the pulmonary vasculature, pulmonary vascular obstructive disease, and genetic variations of vasoactive mediators. Pulmonary input impedance consists of the pulmonary vascular resistance (Rp) and capacitance (Cp). Rp is calculated as the transpulmonary pressure divided by the pulmonary cardiac output, whereas Cp is calculated as the pulmonary stroke volume divided by the pulmonary arterial pulse pressure. The plots of Rp and Cp demonstrate a unique hyperbolic relationship, namely, the resistor-capacitor coupling curve, which represents the pulmonary vascular condition. The product of Rp and Cp is the exponential pressure decay, which refers to the time constant. Alterations in Cp are more considerable in CHD patients at an early stage of developing pulmonary hypertension or with excessive pulmonary blood flow due to a left-to-right shunt. The importance of Cp has gained attention because recent reports have shown that low Cp potentially reflects poor prognosis in patients with CHD-PH and idiopathic pulmonary hypertension. It is also known that Cp levels decrease in specific populations, such as preterm infants and trisomy 21. Therefore, both Rp and Cp should be individually evaluated in the management of children with CHD-PH who have different disease conditions.
Language	English
Publishing date	2022-10-14
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2711999-3
ISSN	2296-2360
ISSN	2296-2360
DOI	10.3389/fped.2022.1011631
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Article ; Online: Transcatheter atrial septal defect closure late after completion of biventricular circulation in patients with pulmonary atresia intact ventricular septum or critical pulmonary stenosis.

Yamda, Hiromu / Muneuchi, Jun / Sugitani, Yuichiro / Ezaki, Hiroki / Koga, Hirotaka / Tanaka, Atsushi / Watanabe, Mamie

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2023 Volume 101, Issue 5, Page(s) 847–852

Abstract: Objective: This study aimed to explore anatomical and hemodynamic features of atrial septal defect, which was treated by transcatheter device closure late after completion of biventricular circulation in patients with pulmonary atresia and intact ... ...

Abstract	Objective: This study aimed to explore anatomical and hemodynamic features of atrial septal defect, which was treated by transcatheter device closure late after completion of biventricular circulation in patients with pulmonary atresia and intact ventricular septum (PAIVS) or critical pulmonary stenosis (CPS). Methods: We studied echocardiographic and cardiac catheterization data, including defect size, retroaortic rim length, single or multiple defects, the presence of malalignment atrial septum, tricuspid and pulmonary valve diameters, and cardiac chamber sizes, in patients with PAIVS/CPS who underwent transcatheter closure of atrial septal defect (TCASD), and compared to control subjects. Results: A total of 173 patients with atrial septal defect, including 8 patients with PAIVS/CPS, underwent TCASD. Age and weight at TCASD were 17.3 ± 18.3 years and 36.6 ± 13.9 kg, respectively. There was no significant difference in defect size (13.7 ± 4.0 vs. 15.6 ± 5.2 mm, p = 0.317) and the retro-aortic rim length (3.7 ± 4.3 vs. 3.6 ± 0.3.1 mm, p = 0.948) between the groups; however, multiple defects (50% vs. 5%, p < 0.001) and malalignment atrial septum (62% vs. 14%. p < 0.001) were significantly frequent in patients with PAIVS/CPS compared to control subjects. The ratio of pulmonary to systemic blood flow in patients with PAIVS/CPS was significantly lower than that in the control patients (1.2 ± 0.4 vs. 2.0 ± 0.7, p < 0.001); however, four out of eight patients with atrial septal defect associated with PAIVS/CPS had right-to-left shunt through a defect, who were evaluated by the balloon occlusion test before TCASD. The indexed right atrial and ventricular areas, the right ventricular systolic pressure, and mean pulmonary arterial pressure did not differ between the groups. After TCASD, the right ventricular end-diastolic area remained unchanged in patients with PAIVS/CPS, whereas it significantly decreased in control subjects. Conclusions: Atrial septal defect associated with PAIVS/CPS had more complex anatomy, which would be a risk for device closure. Hemodynamics should be individually evaluated to determine the indication for TCASD because PAIVS/CPS encompassed anatomical heterogeneity of the entire right heart.
MeSH term(s)	Humans ; Cardiac Catheterization/adverse effects ; Heart Defects, Congenital ; Heart Septal Defects, Atrial/diagnostic imaging ; Heart Septal Defects, Atrial/therapy ; Heart Septal Defects, Atrial/complications ; Pulmonary Atresia/diagnostic imaging ; Pulmonary Atresia/surgery ; Pulmonary Valve Stenosis/diagnostic imaging ; Pulmonary Valve Stenosis/etiology ; Pulmonary Valve Stenosis/surgery ; Treatment Outcome ; Ventricular Septum
Language	English
Publishing date	2023-03-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.30623
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Zs.A 1226: Show issues

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Article: Catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis in a patient after Fontan operation.

Ezaki, Hiroki / Muneuchi, Jun / Imamoto, Naoyuki

Clinical case reports

2020 Volume 9, Issue 1, Page(s) 547–550

Abstract: A 29-year-old man after the Fontan operation had a catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis. Despite combination therapy with cyclophosphamide and methylprednisolone, he was dead at 6 months after the ... ...

Abstract	A 29-year-old man after the Fontan operation had a catastrophic intracranial hemorrhage associated with eosinophilic granulomatous polyangiitis. Despite combination therapy with cyclophosphamide and methylprednisolone, he was dead at 6 months after the onset. The clinical course was worse owing to underlying coagulopathy and endothelial dysfunction associated with congenital heart disease.
Language	English
Publishing date	2020-12-11
Publishing country	England
Document type	Case Reports
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.3579
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Article ; Online: Ventricular Repolarization Dispersion is a Potential Risk for the Development of Life-Threatening Arrhythmia in Children with Hypertrophic Cardiomyopathy.

Tashiro, Naoko / Muneuchi, Jun / Ezaki, Hiroki / Kobayashi, Masaru / Yamada, Hiromu / Sugitani, Yuichiro / Watanabe, Mamie

Pediatric cardiology

2022 Volume 43, Issue 7, Page(s) 1455–1461

Abstract: The risk stratification and early interventions are necessary in patients with hypertrophic cardiomyopathy (HCM), as life-threatening arrhythmia (LTA) is a leading cause of death. This study aimed to explore whether an interval between the peak of the T ... ...

Abstract	The risk stratification and early interventions are necessary in patients with hypertrophic cardiomyopathy (HCM), as life-threatening arrhythmia (LTA) is a leading cause of death. This study aimed to explore whether an interval between the peak of the T wave to the end terminal of the T wave (Tp-e), which represents ventricular repolarization dispersion, could predict the risk for LTA in children with HCM. We analyzed electrocardiography at the first and last visits in children (aged < 15 years) with HCM, and compared Tp-e interval and the ratio of Tp-e interval to QT interval (Tp-e/QT) between children with and without LTA. We studied 25 children with HCM. During the follow-up of 85 (38-146) months, there were 7 children with LTA. The 5-year sudden cardiac death (SCD) risk was 1.4 (1.1-2.5) %, which suggested that our cohort consisted of patients at a lower risk for SCD. Age was significantly older in children with LTA compared to those without it (12.5 vs.1.0 years, P = 0.037), although sex, the presence of family history and symptoms at diagnosis, the maximum left ventricular wall thickness Z-score did not differ between the groups. At the last electrocardiography before LTA, corrected Tp-e interval and Tp-e/QT ratio were significantly greater in patients with LTA compared to those in patients without LTA (corrected Tp-e: 103 vs. 78 ms, P = 0.020; Tp-e/QT: 0.28 vs. 0.22, P = 0.046). Corrected Tp-e and Tp-e/QT ratio cutoff values of 91 ms and 0.28 yielded as the predictors for LTA with sensitivity of 85% and 72%, specificity of 71% and 89%, respectively. Prolonged absolute and corrected Tp-e intervals and an increase in the Tp-e/QT ratio can be useful predictors for LTA in children with HCM. We offer temporal assessments of ventricular repolarization dispersion to stratify the risk for the development of LTA/SCD among children with HCM.
MeSH term(s)	Arrhythmias, Cardiac/etiology ; Cardiomyopathy, Hypertrophic/complications ; Child ; Death, Sudden, Cardiac/epidemiology ; Death, Sudden, Cardiac/etiology ; Electrocardiography ; Heart Ventricles/diagnostic imaging ; Humans
Language	English
Publishing date	2022-03-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	800857-7
ISSN	1432-1971 ; 0172-0643
ISSN (online)	1432-1971
ISSN	0172-0643
DOI	10.1007/s00246-022-02867-3
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Zs.A 1528: Show issues

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Article ; Online: Coronary arterial dominance in patients with congenital heart disease.

Kobayashi, Masaru / Muneuchi, Jun / Sugitani, Yuichiro / Doi, Hirohito / Furuta, Takashi / Ezaki, Hiroki / Watanabe, Mamie

Heart and vessels

2022 Volume 37, Issue 9, Page(s) 1611–1617

Abstract: Coronary arterial dominance is concerned in the management of ischemic heart disease. In particular, right coronary arterial dominance is having a risk for three-vessel coronary artery disease. Thus, this study aimed to explore coronary arterial ... ...

Abstract	Coronary arterial dominance is concerned in the management of ischemic heart disease. In particular, right coronary arterial dominance is having a risk for three-vessel coronary artery disease. Thus, this study aimed to explore coronary arterial dominance in patients with congenital heart disease. The study involved 250 patients, of which 105 patients were with tetralogy of Fallot (TOF), 100 patients with ventricular septal defect (VSD), and 45 patients with Kawasaki disease (KD). We retrospectively reviewed their ascending aortography to determine their coronary arterial dominance, Z-scores of coronary artery diameter, and the ascending aortic curvature, which pertained to the angle between the aortic annulus plane and ascending aortic plane. We identified relevant factors that contribute to having right coronary arterial dominance. Age and weight of the 250 subjects were 2.9 (1.0-8.7) months and 7.7 (5.0-9.4) kg, respectively. The Z-scores of right coronary and anterior descending arteries significantly differed among patients with TOF, VSD, and KD (P < 0.001, P = 0.001). However, there were no significant differences in the Z-scores of left main trunk and circumflex arteries. Right coronary arterial dominance occurred in 89%, 49%, and 61% in patients with TOF, VSD, and KD, respectively (P < 0.001). The presence of TOF was the most powerful predictor for right coronary arterial dominance (odds ratio: 10.31, 95% confidence interval: 4.11-27.2, P < 0.001). We found the robust relationship between right coronary arterial dominance and TOF. Patients with TOF may have an increased risk for the development of coronary artery disease during adulthood.
MeSH term(s)	Adult ; Coronary Artery Disease/diagnostic imaging ; Coronary Vessel Anomalies/diagnostic imaging ; Heart Septal Defects, Ventricular/surgery ; Humans ; Retrospective Studies ; Tetralogy of Fallot
Language	English
Publishing date	2022-03-31
Publishing country	Japan
Document type	Journal Article
ZDB-ID	89678-0
ISSN	1615-2573 ; 0910-8327 ; 0935-736X
ISSN (online)	1615-2573
ISSN	0910-8327 ; 0935-736X
DOI	10.1007/s00380-022-02062-7
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Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito