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Article: A Case of Seronegative Pediatric Neurobrucellosis Presenting With Ataxia.

Qasim, Salman S / Baharoon, Salim / Layqah, Laila

2021 Volume 13, Issue 1, Page(s) e12540

Abstract: Neurobrucellosis is an uncommon and dangerous complication of brucellosis. Meningitis is the most common presentation of neurobrucellosis, but it may present in a wide range of clinical manifestations such as myelitis, brain abscess, radiculopathy, and ... ...

Abstract	Neurobrucellosis is an uncommon and dangerous complication of brucellosis. Meningitis is the most common presentation of neurobrucellosis, but it may present in a wide range of clinical manifestations such as myelitis, brain abscess, radiculopathy, and cranial nerve involvement. It tends to present insidiously with symptoms appearing gradually. Acute presentation of neurobrucellosis is very uncommon. Here, we report a case of a female child who presented with an acute onset of ataxia and slurred speech with positive cerebrospinal fluid (CSF) and neuroimaging findings for neurobrucellosis. In endemic countries such as Saudi Arabia, neurobrucellosis should be considered as a differential diagnosis for patients presenting with unexplained neurological symptoms.
Language	English
Publishing date	2021-01-06
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.12540
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Physician Attitude toward Their Attires and Laundering Habit Changes during the COVID-19: A Cross-Sectional Survey in a Tertiary Care Center.

Alwabel, Reema / Alasmari, Bushra / Alabdulkarim, Aljawhara / Chachar, Yusra / Jahdali, Hamdan A / Layqah, Laila / Baharoon, Salim

Avicenna journal of medicine

2023 Volume 13, Issue 3, Page(s) 169–175

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2023-08-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2664414-9
ISSN	2249-4464 ; 2231-0770
ISSN (online)	2249-4464
ISSN	2231-0770
DOI	10.1055/s-0043-1770935
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Article ; Online: MERS-CoV as an emerging respiratory illness: A review of prevention methods.

Baharoon, Salim / Memish, Ziad A

Travel medicine and infectious disease

2019 Volume 32, Page(s) 101520

Abstract: Introduction: Middle East Respiratory Coronavirus Virus (MERS-CoV) first emerged from Saudi Arabia in 2012 and has since been recognized as a significant human respiratory pathogen on a global level.: Methods: In this narrative review, we focus on ... ...

Abstract	Introduction: Middle East Respiratory Coronavirus Virus (MERS-CoV) first emerged from Saudi Arabia in 2012 and has since been recognized as a significant human respiratory pathogen on a global level. Methods: In this narrative review, we focus on the prevention of MERS-CoV. We searched PubMed, Embase, Cochrane, Scopus, and Google Scholar, using the following terms: 'MERS', 'MERS-CoV', 'Middle East respiratory syndrome' in combination with 'prevention' or 'infection control'. We also reviewed the references of each article to further include other studies or reports not identified by the search. Results: As of Nov 2019, a total of 2468 laboratory-confirmed cases of MERS-CoV were diagnosed mostly from Middle Eastern regions with a mortality rate of at least 35%. A major outbreak that occurred outside the Middle East (in South Korea) and infections reported from 27 countries. MERS-CoV has gained recognition as a pathogen of global significance. Prevention of MERS-CoV infection is a global public health priority. Healthcare facility transmission and by extension community transmission, the main amplifier of persistent outbreaks, can be prevented through early identification and isolation of infected humans. While MERS-CoV vaccine studies were initially hindered by multiple challenges, recent vaccine development for MERS-CoV is showing promise. Conclusions: The main factors leading to sustainability of MERS-CoV infection in high risk courtiers is healthcare facility transmission. MERS-CoV transmission in healthcare facility mainly results from laps in infection control measures and late isolation of suspected cases. Preventive measures for MERS-CoV include disease control in camels, prevention of camel to human transmission.
Keywords	covid19
Language	English
Publishing date	2019-11-12
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	2170891-5
ISSN	1873-0442 ; 1477-8939
ISSN (online)	1873-0442
ISSN	1477-8939
DOI	10.1016/j.tmaid.2019.101520
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Article ; Online: Adequacy of physician clinical rounds and nursing care elements for non-COVID-19 infected patients admitted during the COVID-19 pandemic.

Alrasheed, Abdullah / Shamou, Jinan / Rajendram, Rajkumar / Boqaeid, Abdulaziz / Qasim, Salman / Baharoon, Waleed / Layqah, Laila / Baharoon, Salim

Journal of infection and public health

2022 Volume 15, Issue 6, Page(s) 648–653

Abstract: Background: The COVID-19 pandemic created many challenges for healthcare systems. Frontline workers and especially healthcare professionals were the most severely affected through increased working hours, burnout and major psychological distress.: ... ...

Abstract	Background: The COVID-19 pandemic created many challenges for healthcare systems. Frontline workers and especially healthcare professionals were the most severely affected through increased working hours, burnout and major psychological distress. Objectives: To evaluate the changes in standard care elements which occurred during the COVID-19 pandemic, specifically the physician clinical rounds and nursing care provided to non-COVID-19 infected patients. Design: Observational retrospective study. Settings: The study was conducted at King Abdulaziz Medical City, Riyadh Saudi Arabia. KAMC is a 1200 bed tertiary care referral academic medical center. Patients (materials) and methods: We compared the physician clinical rounds and nursing care elements in all admissions due to non-COVID-19 pneumonia and ST elevation myocardial infarction during the lockdown period with similar admissions in a baseline period in the same weeks in the previous pre-lockdown. Main outcome measures: To evaluates the changes occurring during the COVID-19 pandemic in terms of the standard care elements, such as the physician rounds and nursing care. Sample size: Total of 113 patients records were analyzed. Results: During the lock down period, a total of 113 patients were admitted to the medical and cardiology wards, (95 patients with pneumonia and 18 patients with ST segment elevation myocardial infarction (STEMI)) compared to 89 patients in the pre lockdown period (74 patients with pneumonia and 15 patients with STEMI). Both groups were similar in age, gender, disposition, length of stay, goal of care planning and outcome. Chronic respiratory disease and Diabetes were more present in patients admitted on the pre lockdown time. Azithromycin was more frequently used as part of the initial antibiotic regimen for pneumonia during the pre-lockdown while doxycycline was significantly more during the lockdown. For the 95 patients admitted in the medical wards during the lockdown, there were a total of 820 physicians' clinical rounds opportunities for senior and junior physicians each. The residents missed 133 (16.2%) and consultant missed 252 (30.7%) of those clinical rounds opportunities. Missed clinical rounds opportunities during the pre-lock down period was higher for residents and consultants at 19.3% (P = 0.429 ) and 36.3% respectively (P = 0.027 ). Similarly, missed clinical rounds opportunities was less during the lockdown period from 35.2% to 25% (p 0.022) and from 38.8% to 30.6% (p = 1 ) for junior staff and consultant cardiology respectively compared to pre lockdown period. For nursing care elements, there was a decrease in missed opportunities in vital signs measurement (p 0.47 and p 0.226), pain assessment (p 0.088 and p 0,366) and skin care (p 0.249 and p 0.576) for patients admitted during the lockdown period in medical and cardiology wards. Conclusions: Caring for patients admitted for non COVID 19 infection reasons, physicians' clinical rounds did marginally increase compared to pre lockdown period while nurses monitoring for those patients was significantly higher. No difference in mortality was observed for patients admitted pre and during lockdown. The number of missed opportunities to do clinical rounds by physicians remains high during both periods and measures to improve adherence of physicians to performed clinical rounds are needed.
MeSH term(s)	Humans ; COVID-19 ; ST Elevation Myocardial Infarction/diagnosis ; SARS-CoV-2 ; Retrospective Studies ; Pandemics ; Teaching Rounds ; Communicable Disease Control ; Physicians
Language	English
Publishing date	2022-04-28
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2467587-8
ISSN	1876-035X ; 1876-0341
ISSN (online)	1876-035X
ISSN	1876-0341
DOI	10.1016/j.jiph.2022.04.004
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Article: A Clot in Transit: A Cause of Death or a Bystander?

Almahlawi, Al-Zahraa / Alghamdi, Mohammad / Althobaiti, Mutaz / Alahmadi, Duha / Almalki, Yazeed / Alsahli, Rahaf / Aljahdali, Hamdan A / Shamou, Jinan / Baharoon, Salim

Journal of the Saudi Heart Association

2023 Volume 35, Issue 2, Page(s) 135–143

Abstract: Introduction: The clot in transit is a rare manifestation of thromboembolic disease occurring usually in the setting of PE and frequently associated with poor outcomes. The best therapeutic option is not well established. We describe a series of 35 ... ...

Abstract	Introduction: The clot in transit is a rare manifestation of thromboembolic disease occurring usually in the setting of PE and frequently associated with poor outcomes. The best therapeutic option is not well established. We describe a series of 35 patients diagnosed with clots in transit including their therapeutic interventions and outcome between the period January 2016 to December 2020. Methods: a retrospective chart review of all patients with an Echocardiogram showing thrombi in the right heart chambers including patients with thrombus in the presence of central lines or other devices. We exclude patients where masses were described as tumors or vegetation and masses in the presence of bacteremia. Results: There were 35 patients with echocardiographic evidence of a thrombus in the right heart chambers. In 12 of those patients, the thrombus was related to an intracardiac catheter. 37.1% of CT chest was done along with Echocardiogram and showed a concomitant PE in 77%. On echocardiogram, 66% of the thrombi were mobile. RV strain was present in 17% while abnormal RVSP (>30 mmHg) was present in 74%. Respiratory support was required in 37.1% and only 17% required inotropic support. There was a total or partial resolution in 80% those who had repeated echocardiogram after four weeks of therapy. Heparin was started in the majority of patients (74%). Warfarin was the most frequently used follow-up anti-coagulant in 51.4%. The mortality rate was significantly higher in those patients with RVSP >50, UFH group, O2 or inotropic support. 26% of patients died within the first 28 days after the diagnosis, while first 7 days mortality was 6% only. Conclusion: a clot in transit in our study was not directly associated with poor outcomes in the first week of therapy, UFH is still the most frequently used initial method to treat clots in transit. However, only 26% had a total resolution of clot within 4 weeks of treatment.
Language	English
Publishing date	2023-05-27
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	2515647-0
ISSN	1016-7315
ISSN	1016-7315
DOI	10.37616/2212-5043.1337
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Article ; Online: Disseminated tuberculosis: Clinical presentation, diagnosis, and outcomes in a tertiary-care hospital in Saudi Arabia.

Abuabat, Faisal / Badri, Motasim / Abuabat, Salman / Alsultan, Sultan / Baharoon, Salim / Alharbi, Abdullah / Khan, Ayaz / Al-Jahdali, Hamdan

International journal of mycobacteriology

2023 Volume 12, Issue 4, Page(s) 407–411

Abstract: Background: Tuberculosis (TB) is the primary infectious cause of mortality worldwide. Although TB incidence and prevalence are declining, the use of immunosuppressive drugs and the growing prevalence of immunocompromising conditions such as ... ...

Abstract	Background: Tuberculosis (TB) is the primary infectious cause of mortality worldwide. Although TB incidence and prevalence are declining, the use of immunosuppressive drugs and the growing prevalence of immunocompromising conditions such as comorbidities, malignancies, and the use of immunosuppressive agents are risk factors for disseminated TB (DTB). This study aims to identify the relevant clinical, laboratory, radiological, and histopathological features of DTB, as well as to assess the typical anatomical distributions and treatment outcomes of patients diagnosed with the disease at King Abdulaziz Medical City (KAMC). Methods: A retrospective chart review was conducted, including all patients diagnosed with miliary or DTB at KAMC with retrievable medical files. Results: The study included 55 patients, of whom 35 (63.6%) were male and the median age was 64 years old. 35 (63.6%) of the infected patients were timely diagnosed and eventually cured from the illness. The most common comorbid conditions were diabetes, chronic kidney disease, and immunocompromising conditions, which were present in 37 (67.2%), 12 (21.8%), and 11 (20%) of the patients, respectively. The most common presenting symptoms were fever and cough, present in 31 (56.3%) and 26 (47.2%) of the patients, respectively, followed by weight loss in 25 (45.4%), night sweats in 15 (27.2%), and shortness of breath in 14 (25.4%). Approximately two-thirds of the patients had pulmonary miliary TB (MTB) (38; 69.1%), followed by TB lymphadenitis (21; 38.2%), central nervous system involvement (13; 23.6%), skeletal involvement (11; 20%), gastrointestinal involvement (5; 9.1%), pleural involvement (3; 5.5%), and urogenital TB (2; 3.6%). The mortality rate was 14 (25.5%) patients. Conclusion: MTB is challenging to diagnose due to nonspecific clinical, laboratory, and imaging findings. Clinicians dealing with patients who are at risk of developing DTB should be aware of the typical presentations and abnormal clinical findings. They should also have a low threshold to initiate specific investigations for the disease, as early diagnosis and effective treatment is critical in reducing morbidity and mortality rates.
MeSH term(s)	Humans ; Male ; Middle Aged ; Female ; Retrospective Studies ; Saudi Arabia/epidemiology ; Tertiary Care Centers ; Tuberculosis, Miliary/diagnosis ; Tuberculosis, Miliary/drug therapy ; Tuberculosis, Miliary/epidemiology ; Risk Factors
Language	English
Publishing date	2023-12-23
Publishing country	India
Document type	Journal Article
ZDB-ID	2696590-2
ISSN	2212-554X ; 2212-554X
ISSN (online)	2212-554X
ISSN	2212-554X
DOI	10.4103/ijmy.ijmy_141_23
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Article ; Online: Recurrent Urinary Tract Infection in Adult Patients, Risk Factors, and Efficacy of Low Dose Prophylactic Antibiotics Therapy.

Alghoraibi, Hala / Asidan, Aisha / Aljawaied, Raneem / Almukhayzim, Raghad / Alsaydan, Aljoharah / Alamer, Elaf / Baharoon, Waleed / Masuadi, Emad / Al Shukairi, Abeer / Layqah, Laila / Baharoon, Salim

Journal of epidemiology and global health

2023 Volume 13, Issue 2, Page(s) 200–211

Abstract: Background: Recurrent urinary tract infection (UTI) occurs in sizable percentages of patients after a single episode and is a frequent cause of primary healthcare visits and hospital admissions, accounting for up to one quarter of emergency department ... ...

Abstract	Background: Recurrent urinary tract infection (UTI) occurs in sizable percentages of patients after a single episode and is a frequent cause of primary healthcare visits and hospital admissions, accounting for up to one quarter of emergency department visits. We aim to describe the pattern of continuous antibiotic prophylaxis prescription for recurrent urinary tract infections, in what group of adult patients they are prescribed and their efficacy. Methods: A retrospective chart review of all adult patients diagnosed with single and recurrent symptomatic urinary tract infection in the period of January 2016 to December 2018. Results: A total of 250 patients with a single UTI episode and 227 patients with recurrent UTI episodes were included. Risk factors for recurrent UTI included diabetes mellitus, chronic renal disease, and use of immunosuppressive drugs, renal transplant, any form of urinary tract catheterization, immobilization and neurogenic bladder. E. coli infections were the most prevalent organism in patients with UTI episodes. Prophylactic antibiotics were given to 55% of patients with UTIs, Nitrofurantoin, Bactrim or amoxicillin clavulanic acid. Post renal transplant is the most frequent reason to prophylaxis antibiotics (44%). Bactrim was more prescribed in younger patients (P < 0.001), in post-renal transplantation (P < 0.001) and after urological procedures (P < 0.001), while Nitrofurantoin was more prescribed in immobilized patients (P = 0.002) and in patients with neurogenic bladder (P < 0.001). Patients who received continuous prophylactic antibiotics experienced significantly less episodes of urinary tract infections (P < 0.001), emergency room visits and hospital admissions due to urinary tract infections (P < 0.001). Conclusion: Despite being effective in reducing recurrent urinary tract infection rate, emergency room visits and hospital admissions due to UTI, continuous antibiotic prophylaxis was only used in 55% of patients with recurrent infections. Trimethoprim/sulfamethoxazole was the most frequently used prophylactic antibiotic. Urology and gynecological referral were infrequently requested as part of the evaluation process for patients with recurrent UTI. There was a lack of use of other interventions such as topical estrogen in postmenopausal women and documentation of education on non-pharmacological methods to decrease urinary tract infections.
MeSH term(s)	Humans ; Adult ; Female ; Antibiotic Prophylaxis/adverse effects ; Antibiotic Prophylaxis/methods ; Nitrofurantoin/therapeutic use ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use ; Escherichia coli ; Retrospective Studies ; Urinary Bladder, Neurogenic/complications ; Urinary Bladder, Neurogenic/drug therapy ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/epidemiology ; Urinary Tract Infections/prevention & control ; Anti-Bacterial Agents/therapeutic use ; Escherichia coli Infections ; Risk Factors
Chemical Substances	Nitrofurantoin (927AH8112L) ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2) ; Anti-Bacterial Agents
Language	English
Publishing date	2023-06-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2645324-1
ISSN	2210-6014 ; 2210-6014
ISSN (online)	2210-6014
ISSN	2210-6014
DOI	10.1007/s44197-023-00105-4
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Article: Medical error reporting: is it about physicians' knowledge and their practice, or patient safety culture in the workplace?

Azer, S A / Baharoon, Salim

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

2016 Volume 22, Issue 3, Page(s) 228–229

MeSH term(s)	Health Knowledge, Attitudes, Practice ; Humans ; Medical Errors ; Organizational Culture ; Patient Safety ; Physicians/psychology ; Surveys and Questionnaires ; Truth Disclosure
Language	English
Publishing date	2016-06-15
Publishing country	Egypt
Document type	Letter
ZDB-ID	1291071-5
ISSN	1687-1634 ; 1020-3397
ISSN (online)	1687-1634
ISSN	1020-3397
DOI	10.26719/2016.22.3.228
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Article: Influence of halloysite nanotubes on the efficiency of Asparaginase against mice Ehrlich solid carcinoma.

Baharoon, B M M / Shaik, A M / El-Hamidy, Salim M / Eid El-Araby, Rady / Batawi, Ashwaq H / Abdel Salam, Mohamed

Saudi journal of biological sciences

2022 Volume 29, Issue 5, Page(s) 3626–3634

Abstract: Herein, the impact of the halloysite nanotubes to suppress the side effects of Asparaginase (ANase) cellular proliferation was investigated. Methods: A total of 100 adult male mice was employed. These mice were divided into four equal groups; Group 1 ( ... ...

Abstract	Herein, the impact of the halloysite nanotubes to suppress the side effects of Asparaginase (ANase) cellular proliferation was investigated. Methods: A total of 100 adult male mice was employed. These mice were divided into four equal groups; Group 1 (control), Group 2 (ESC group) of a single dose of 0.15 ml Ehrlich cells (2 × 10
Language	English
Publishing date	2022-03-04
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	2515206-3
ISSN	2213-7106 ; 1319-562X
ISSN (online)	2213-7106
ISSN	1319-562X
DOI	10.1016/j.sjbs.2022.02.058
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Article ; Online: Adequacy of physician clinical rounds and nursing care elements for non-COVID-19 infected patients admitted during the COVID-19 pandemic

Abdullah Alrasheed / Jinan Shamou / Rajkumar Rajendram / Abdulaziz Boqaeid / Salman Qasim / Waleed Baharoon / Laila layqah / Salim Baharoon

Journal of Infection and Public Health, Vol 15, Iss 6, Pp 648-

2022 Volume 653

Abstract	Background: The COVID-19 pandemic created many challenges for healthcare systems. Frontline workers and especially healthcare professionals were the most severely affected through increased working hours, burnout and major psychological distress. Objectives: To evaluate the changes in standard care elements which occurred during the COVID-19 pandemic, specifically the physician clinical rounds and nursing care provided to non-COVID-19 infected patients. Design: Observational retrospective study. Settings: The study was conducted at King Abdulaziz Medical City, Riyadh Saudi Arabia. KAMC is a 1200 bed tertiary care referral academic medical center. Patients (materials) and methods: We compared the physician clinical rounds and nursing care elements in all admissions due to non-COVID-19 pneumonia and ST elevation myocardial infarction during the lockdown period with similar admissions in a baseline period in the same weeks in the previous pre-lockdown. Main outcome measures: To evaluates the changes occurring during the COVID-19 pandemic in terms of the standard care elements, such as the physician rounds and nursing care. Sample size: Total of 113 patients records were analyzed. Results: During the lock down period, a total of 113 patients were admitted to the medical and cardiology wards, (95 patients with pneumonia and 18 patients with ST segment elevation myocardial infarction (STEMI)) compared to 89 patients in the pre lockdown period (74 patients with pneumonia and 15 patients with STEMI). Both groups were similar in age, gender, disposition, length of stay, goal of care planning and outcome. Chronic respiratory disease and Diabetes were more present in patients admitted on the pre lockdown time. Azithromycin was more frequently used as part of the initial antibiotic regimen for pneumonia during the pre-lockdown while doxycycline was significantly more during the lockdown.For the 95 patients admitted in the medical wards during the lockdown, there were a total of 820 physicians’ clinical rounds opportunities ...
Keywords	COVID-19 ; Pandemic ; Clinical round ; MI ; Pneumonia ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
Subject code	610
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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