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  1. Article ; Online: Fatigue, Weight Loss, and Acute Chest Pain in a 15-year-old Boy.

    Parr, Madeline F E / Clouser, Katharine N / Tozzi, Meghan / Bhavsar, Sejal M

    Pediatrics in review

    2023  Volume 44, Issue 12, Page(s) 716–719

    MeSH term(s) Male ; Humans ; Adolescent ; Chest Pain/etiology ; Fatigue/etiology ; Weight Loss
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 774515-1
    ISSN 1526-3347 ; 0191-9601
    ISSN (online) 1526-3347
    ISSN 0191-9601
    DOI 10.1542/pir.2022-005552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Using health information technology to support the needs of Children with Medical Complexity: Mapping review of consumer informatics applications.

    Asan, Onur / Elkefi, Safa / Clouser, Katharine N / Percy, Stephen

    Frontiers in digital health

    2022  Volume 4, Page(s) 992838

    Abstract: Background: Children with medical complexity (CMC) are fragile populations that require continuous care and supervision. CMC family caregivers experience many challenges trying to address CMC patients' needs which puts these caregivers in a stressful ... ...

    Abstract Background: Children with medical complexity (CMC) are fragile populations that require continuous care and supervision. CMC family caregivers experience many challenges trying to address CMC patients' needs which puts these caregivers in a stressful situation that may negatively impact the care of CMC patients. Consumer informatics might help these caregivers in coordinating care. However, few consumer informatics applications explicitly focus on supporting CMC caregivers' needs.
    Objective: This systematic mapping literature review aims to provide an overview and a structured understanding of the consumer informatics designed for CMC and their caregivers.
    Methods: We followed a systematic mapping literature review process to provide an overview of the existing Consumer Informatics literature for CMC, which is the scope of our study. We screened IEEE Xplore, Web of Science, and PubMed databases using a preset list of mesh terms that cover the use of medical informatics by children with medical complexities and their caregivers. The selected articles are peer-reviewed English publications that were empirically validated from January 2002 to January 2022. After selecting and filtering the articles, we analyzed them based on the preset mapping questions using the following criteria: publication year, publication source, research type, contribution type, empirical type, the need addressed, target audience, technology users, and consumer informatics' type.
    Results: The initial search resulted in a number of (
    Conclusions: CMC consumer informatics is a promising research field to present novel initiatives and approaches to manage the caregivers' workload. Future research should be shifted toward providing more evidence-based studies to examine the effectiveness of CMC consumer informatics solutions and identify the related challenges and limitations.
    Language English
    Publishing date 2022-12-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-253X
    ISSN (online) 2673-253X
    DOI 10.3389/fdgth.2022.992838
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hospital and ICU Admission Risk Associated With Comorbidities Among Children With COVID-19 Ancestral Strains.

    Ungar, Stephanie P / Solomon, Sadie / Stachel, Anna / Shust, Gail F / Clouser, Katharine N / Bhavsar, Sejal M / Lighter, Jennifer

    Clinical pediatrics

    2023  Volume 62, Issue 9, Page(s) 1048–1058

    Abstract: A large proportion of children have been affected by COVID-19; we evaluated the association between comorbidities and hospitalization/ICU (intensive care unit) admission among 4097 children under age 21 years with symptomatic COVID-19 (not just ... ...

    Abstract A large proportion of children have been affected by COVID-19; we evaluated the association between comorbidities and hospitalization/ICU (intensive care unit) admission among 4097 children under age 21 years with symptomatic COVID-19 (not just polymerase chain reaction [PCR]-positive or multisystem inflammatory syndrome in children associated with COVID-19 [MIS-C]) from 2 large health systems from March 2020 to September 2021. Significant comorbidities and demographic factors identified by univariable analysis were included in a multivariable logistic regression compared with children ages 6 to 11 without comorbidities. In all, 475 children (11.6%) were hospitalized, of whom 25.5% required ICU admission. Children under 1 year had high hospitalization risk, but low risk of ICU admission. Presence of at least 1 comorbidity was associated with hospitalization and ICU admission (odds ratio [OR] > 4). Asthma, obesity, chronic kidney disease, sickle cell disease, bone marrow transplantation, and neurologic disorders were associated with hospitalization (adjusted odds ratio [AOR] > 2). Malignancy, intellectual disability, and prematurity were associated with ICU admission (AOR > 4). Comorbidities are significantly associated with hospitalization/ICU admission among children with COVID-19.
    MeSH term(s) Humans ; Child ; Young Adult ; Adult ; COVID-19/epidemiology ; SARS-CoV-2 ; Risk Factors ; Hospitalization ; Comorbidity ; Intensive Care Units ; Hospitals ; Retrospective Studies
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228221150605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Characteristics and Presentations of Hospitalized Children Due to 3 Predominate COVID-19 Variants Within a Health Care Network.

    Bhavsar, Sejal M / Clouser, Katharine N / Connolly, Hailey / Gadhavi, Jasmine / Kaur, Ranbir / Lozy, Tara / Naganathan, Srividya / Pierre, Margarette / Riollano Cruz, Mariawy / Shah, Pooja / Siu, Anita / Swenson, Carly / Ballance, Cathleen

    Clinical pediatrics

    2023  Volume 63, Issue 1, Page(s) 66–72

    Abstract: Objective of this article is to describe differences in the demographic and clinical characteristics, severity of illness, and outcomes in pediatric patients with different SARS-CoV-2 variants. We conducted a retrospective study of pediatric patients ... ...

    Abstract Objective of this article is to describe differences in the demographic and clinical characteristics, severity of illness, and outcomes in pediatric patients with different SARS-CoV-2 variants. We conducted a retrospective study of pediatric patients admitted with COVID-19 during the 3 large waves of infection within a health network in New Jersey. We included demographic characteristics, clinical features, and outcomes and compared the data with respect to the different variants. Of 351 total patients included in this study, 74 were admitted during wave 1, 94 during wave 2, and 181 during wave 3. The median age of patients decreased from wave 1 (11.5 years) to wave 3 (3 years) (
    MeSH term(s) Adult ; Humans ; Child ; Infant ; Child, Hospitalized ; SARS-CoV-2 ; COVID-19/epidemiology ; COVID-19/therapy ; Retrospective Studies ; Delivery of Health Care
    Language English
    Publishing date 2023-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231207314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: COVID-19 in Pediatric Inpatients: A Multi-Center Observational Study of Factors Associated with Negative Short-Term Outcomes.

    Rubenstein, Sara / Grew, Emily / Clouser, Katharine / Kwok, Alexander / Veerapandiyan, Aravindhan / Kornitzer, Jeffrey / Pecor, Keith / Ming, Xue

    Children (Basel, Switzerland)

    2021  Volume 8, Issue 11

    Abstract: Most cases of COVID-19 in children and adolescents are mild or asymptomatic, but a small number of individuals may develop severe disease, requiring PICU admission and/or mechanical ventilation. We assessed the factors associated with negative short-term ...

    Abstract Most cases of COVID-19 in children and adolescents are mild or asymptomatic, but a small number of individuals may develop severe disease, requiring PICU admission and/or mechanical ventilation. We assessed the factors associated with negative short-term outcomes of COVID-19 in 82 pediatric patients at three hospitals within the United States during the spring and summer of 2020 using medical records, laboratory data, and imaging studies of all patients admitted with a positive RT-PCR test for SARS-CoV-2. We found that older patients were more likely to have an extended hospital stay, and those with high BMIs (over 25) were more likely to be admitted to the PICU during the early pandemic. In addition, older patients, those with high BMIs, and those with underlying medical conditions, were more likely to receive respiratory support. Given the association of age, BMI, and underlying medical conditions with more severe COVID-19, clinicians should keep these factors in mind when treating patients.
    Language English
    Publishing date 2021-10-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children8110951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: COVID-19 Infection Associated With Encephalitis in an Adolescent.

    Bhavsar, Sejal M / Agarwal, Saranga / Lewis, Rachel / Ganta, Avani / Roshchina, Yelena S / Clouser, Katharine N / Baer, Aryeh Z / Gliksman, Felicia / Piwoz, Julia A

    Neurology. Clinical practice

    2021  Volume 11, Issue 2, Page(s) e189–e192

    Language English
    Publishing date 2021-03-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2645818-4
    ISSN 2163-0933 ; 2163-0402
    ISSN (online) 2163-0933
    ISSN 2163-0402
    DOI 10.1212/CPJ.0000000000000911
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: MIS-C After ARDS Associated With SARS-CoV-2.

    Clouser, Katharine / Baer, Aryeh / Bhavsar, Sejal / Gadhavi, Jasmine / Li, Suzanne / Schnall, Jeremy / Weiss, Jennifer E

    The Pediatric infectious disease journal

    2020  Volume 39, Issue 11, Page(s) e363–e365

    Abstract: This is a case of an 11-year-old female who was admitted with respiratory failure, requiring intubation while testing positive for SARS-CoV-2. During her recovery, she had new onset fevers and uptrending inflammatory markers. After an evaluation of ... ...

    Abstract This is a case of an 11-year-old female who was admitted with respiratory failure, requiring intubation while testing positive for SARS-CoV-2. During her recovery, she had new onset fevers and uptrending inflammatory markers. After an evaluation of infectious causes, the diagnosis of MIS-C was made approximately 1 month after her initial symptoms.
    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Child ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Female ; Fever/virology ; Humans ; Pandemics ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Respiratory Distress Syndrome/physiopathology ; Respiratory Distress Syndrome/therapy ; Respiratory Distress Syndrome/virology ; Respiratory Insufficiency/virology ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/physiopathology ; Systemic Inflammatory Response Syndrome/therapy ; Systemic Inflammatory Response Syndrome/virology
    Keywords covid19
    Language English
    Publishing date 2020-09-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: MIS-C After ARDS Associated With SARS-CoV-2

    Clouser, Katharine / Baer, Aryeh / Bhavsar, Sejal / Gadhavi, Jasmine / Li, Suzanne / Schnall, Jeremy / Weiss, Jennifer E

    Pediatr Infect Dis J

    Abstract: This is a case of an 11-year-old female who was admitted with respiratory failure, requiring intubation while testing positive for SARS-CoV-2. During her recovery, she had new onset fevers and uptrending inflammatory markers. After an evaluation of ... ...

    Abstract This is a case of an 11-year-old female who was admitted with respiratory failure, requiring intubation while testing positive for SARS-CoV-2. During her recovery, she had new onset fevers and uptrending inflammatory markers. After an evaluation of infectious causes, the diagnosis of MIS-C was made approximately 1 month after her initial symptoms.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #748528
    Database COVID19

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  9. Article ; Online: COVID-19 in Pediatrics: Characteristics of Hospitalized Children in New Jersey.

    Bhavsar, Sejal M / Clouser, Katharine N / Gadhavi, Jasmine / Anene, Okechukwu / Kaur, Ranbir / Lewis, Rachel / Naganathan, Srividya / Michalak, Zuzanna / Chen, Clara Q / Shah, Pooja / Siu, Anita / Ballance, Cathleen

    Hospital pediatrics

    2020  Volume 11, Issue 1, Page(s) 79–87

    Abstract: Objectives: Understanding the risk factors, predictors, and clinical presentation of coronavirus disease 2019 (COVID-19) in pediatric patients with severe disease.: Methods: We conducted a retrospective chart review of pediatric patients admitted ... ...

    Abstract Objectives: Understanding the risk factors, predictors, and clinical presentation of coronavirus disease 2019 (COVID-19) in pediatric patients with severe disease.
    Methods: We conducted a retrospective chart review of pediatric patients admitted between March 1, 2020, and May 31, 2020, to a large health network in New Jersey with positive test results for severe acute respiratory syndrome coronavirus 2 on reverse transcriptase polymerase chain reaction, rapid testing, or serum immunoglobulin G testing; we included demographic characteristics, clinical features, and outcomes.
    Results: A total of 81 patients ≤21 years old were admitted with positive test results for severe acute respiratory syndrome coronavirus 2 on reverse transcriptase polymerase chain reaction and/or serum immunoglobulin testing. Sixty-seven patients (82.7%) were admitted for management of acute COVID-19 infection, whereas 14 (17.3%) were admitted for management of multisystem inflammatory syndrome in children (MIS-C). Of the 81 hospitalized patients, 28 (34.6%) required intensive care. A majority of patients (42 [51.9%]) admitted for both acute COVID-19 infection and MIS-C were Hispanic. Underlying chronic health conditions were not present in most patients. Obesity (mean BMI of 41.1) was noted in the patients with MIS-C requiring ICU care, although not statistically significant. Absolute lymphopenia and elevated levels of inflammatory markers were statistically significant in the patients with MIS-C treated in the ICU.
    Conclusions: This study adds to the growing literature of potential risk factors for severe disease in pediatric patients due to COVID-19 infection and MIS-C. Patients of Hispanic ethnicity represented the majority of patients with both acute COVID-19 infection and MIS-C, despite only representing 10% to 20% of the population our hospitals serve. Infants and patients with chronic health conditions were not at increased risk for severe disease. Absolute lymphopenia and elevated levels of inflammatory markers were associated with more severe disease.
    Language English
    Publishing date 2020-12-29
    Publishing country United States
    Document type Journal Article
    ISSN 2154-1671
    ISSN (online) 2154-1671
    DOI 10.1542/hpeds.2020-001719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Short-Term Outcomes After Multisystem Inflammatory Syndrome in Children Treatment.

    Clouser, Katharine N / Gadhavi, Jasmine / Bhavsar, Sejal M / Lewis, Rachel / Ballance, Cathleen / Michalak, Zuzanna / Baer, Aryeh / Kriegel, Marni / Pall, Harpreet / Piwoz, Julia / Slavin, Kevin / Siegel, Mark E / Tozzi, Meghan E / Tozzi, Robert / Walker, David M / Lapidus, Sivia / Aschner, Judy

    Journal of the Pediatric Infectious Diseases Society

    2020  Volume 10, Issue 1, Page(s) 52–56

    Abstract: This is a retrospective chart review of 20 patients treated with a consensus-driven treatment algorithm in multisystem inflammatory syndrome in children patients across a wide clinical spectrum. Their treatments and clinical status are described as well ... ...

    Abstract This is a retrospective chart review of 20 patients treated with a consensus-driven treatment algorithm in multisystem inflammatory syndrome in children patients across a wide clinical spectrum. Their treatments and clinical status are described as well as their favorable return to functional baseline by 30 days post presentation.
    MeSH term(s) Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Algorithms ; COVID-19/diagnostic imaging ; COVID-19/drug therapy ; COVID-19/therapy ; Child ; Child, Preschool ; Clinical Protocols ; Echocardiography ; Female ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Infant ; Male ; Retrospective Studies ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/diagnostic imaging ; Systemic Inflammatory Response Syndrome/drug therapy ; Systemic Inflammatory Response Syndrome/therapy ; Treatment Outcome
    Chemical Substances Adrenal Cortex Hormones ; Immunoglobulins, Intravenous
    Language English
    Publishing date 2020-11-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2668791-4
    ISSN 2048-7207 ; 2048-7193
    ISSN (online) 2048-7207
    ISSN 2048-7193
    DOI 10.1093/jpids/piaa151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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