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  1. Article ; Online: Improving the solubility and interfacial absorption of hempseed protein via a novel high pressure homogenization-assisted pH-shift strategy.

    Wang, Qingling / Tang, Ziwei / Cao, Yanyun / Ming, Yu / Wu, Mangang

    Food chemistry

    2024  Volume 442, Page(s) 138447

    Abstract: A pH shift treatment aided by high pressure homogenization (HPH) with various pressures (0-120 MPa) was employed to structurally modify hempseed protein isolate (HPI). Compared with individual pH shift or HPH treatment, HPH-assisted pH shift improved the ...

    Abstract A pH shift treatment aided by high pressure homogenization (HPH) with various pressures (0-120 MPa) was employed to structurally modify hempseed protein isolate (HPI). Compared with individual pH shift or HPH treatment, HPH-assisted pH shift improved the structural flexibility of HPI, as revealed by the increased random coil in protein secondary structure. With the incorporation of HPH into pH shift, the intrinsic fluorescence intensity was remarkably attenuated and redshifted, whereas the surface hydrophobicity was pronouncedly boosted, indicating the extensive unfolding of protein structure. Moreover, the cotreated HPI exhibited a smaller and more homogenous particle size, notably at a higher pressure. Consequently, the solubility was drastically raised by the cooperated treatments, to the maximum value (62.8 %) at 120 MPa. These physicochemical changes in the cotreated HPI facilitated a consolidated interfacial activity. Moreover, the cooperated treatment, especially highly pressured (120 MPa), facilitated the penetration and rearrangement of proteins at the oil-water interface.
    MeSH term(s) Solubility ; Pressure ; Plant Proteins/chemistry ; Particle Size ; Hydrogen-Ion Concentration
    Chemical Substances Plant Proteins
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2024.138447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A gauge of coral physiology: re-examining temporal changes in

    Chuang, Po-Shun / Yu, Sheng-Ping / Liu, Po-Yu / Hsu, Ming-Tsung / Chiou, Yu-Jing / Lu, Chih-Ying / Tang, Sen-Lin

    ISME communications

    2024  Volume 4, Issue 1, Page(s) ycae001

    Abstract: Bacteria contribute to many physiological functions of coral holobionts, including responses to bleaching. The bacterial genus, ...

    Abstract Bacteria contribute to many physiological functions of coral holobionts, including responses to bleaching. The bacterial genus,
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ISSN 2730-6151
    ISSN (online) 2730-6151
    DOI 10.1093/ismeco/ycae001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Phosphorus recovery from phosphate tailings through a two-stage leaching-precipitation process: Toward the harmless and reduction treatment of P-bearing wastes.

    Yu, Yao-Hui / Du, Chuan-Ming / Zhang, Yu-Tang / Yuan, Rui-Yuan

    Environmental research

    2024  Volume 248, Page(s) 118328

    Abstract: To achieve highly efficient extraction of phosphorus (P) and comprehensive utilization of phosphate tailings, a two-stage leaching-precipitation method was proposed. Phosphate tailings primarily consisted of dolomite, fluorapatite, and quartz. During the ...

    Abstract To achieve highly efficient extraction of phosphorus (P) and comprehensive utilization of phosphate tailings, a two-stage leaching-precipitation method was proposed. Phosphate tailings primarily consisted of dolomite, fluorapatite, and quartz. During the first-stage leaching, the large majority of dolomite was selectively dissolved and the leaching efficiency of Mg reached 93.1 % at pH 2.0 and 60 °C. The subsequent second-stage leaching of fluorapatite was performed and the P leaching efficiency was 98.8 % at pH 1.5 and 20 °C, while the quartz remained in the residue. Through two-stage leaching, a stepwise leaching of dolomite and fluorapatite was achieved. After chemical precipitation, calcium phosphate with a high purity of 97.9 % was obtained; and the total recovery efficiency of P exceeded 98 %. The obtained calcium phosphate can be a raw material in the phosphorus chemical industry, while the Mg-rich leachate and the final quartz-rich residue have the potential for Mg extraction and the production of mortars or geopolymers, respectively. The two-stage leaching-precipitation process could significantly reduce the leaching costs, and enhance the reaction rates. It is expected to realize a volume reduction and efficient resource utilization of the phosphate tailings by using this sustainable and promising solution.
    MeSH term(s) Phosphorus ; Phosphates/chemistry ; Quartz ; Apatites ; Calcium Carbonate ; Magnesium
    Chemical Substances Phosphorus (27YLU75U4W) ; Phosphates ; calcium magnesium carbonate (UG9H2002BF) ; fluorapatite (M4CM1H238J) ; Quartz (14808-60-7) ; Apatites ; Calcium Carbonate (H0G9379FGK) ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 2024-01-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118328
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ipsilateral Upper-Limb Lymphedema After COVID-19 Vaccine Booster: Reply.

    Tang, Charlene Yu Lin / Chua, Wei Ming

    Clinical nuclear medicine

    2023  Volume 48, Issue 9, Page(s) 837

    MeSH term(s) Humans ; Female ; COVID-19 ; Upper Extremity ; Lymphedema/diagnostic imaging ; Lymphedema/etiology ; Breast Neoplasms
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000004741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Transcription Factor Pdr3p Promotes Carotenoid Biosynthesis by Activating

    Chen, Ming-Kai / Zhang, Tang-Lei / Sun, Ming-Ze / Yu, Hong-Wei / Ye, Li-Dan

    ACS synthetic biology

    2024  Volume 13, Issue 2, Page(s) 590–597

    Abstract: Pleiotropic drug resistance (PDR) family proteins have been extensively studied for their roles in transporting hydrophobic substances, including carotenoids. Overexpression of the PDR family regulator Pdr3p was recently found to boost the biosynthesis ... ...

    Abstract Pleiotropic drug resistance (PDR) family proteins have been extensively studied for their roles in transporting hydrophobic substances, including carotenoids. Overexpression of the PDR family regulator Pdr3p was recently found to boost the biosynthesis of carotenoids, which could not be explained by enhanced product secretion due to the meager extracellular proportions. To provide insights into the possible mechanism, comparative transcriptomics, reverse metabolic engineering, and electrophoretic mobility shift assay (EMSA) were conducted. Transcriptomic data suggested an unexpected correlation between Pdr3p overexpression and the transcriptional levels of
    MeSH term(s) Transcription Factors/genetics ; Transcription Factors/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; DNA-Binding Proteins/metabolism ; Trans-Activators/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; ATP-Binding Cassette Transporters/genetics
    Chemical Substances Transcription Factors ; DNA-Binding Proteins ; Trans-Activators ; Saccharomyces cerevisiae Proteins ; ATP-Binding Cassette Transporters
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ISSN 2161-5063
    ISSN (online) 2161-5063
    DOI 10.1021/acssynbio.3c00547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: 

    Zhao, Liao-Chen / Chen, Ren / Yu, Zhi-Yong / Tang, Ming / Yang, Qin-Er

    PhytoKeys

    2023  Volume 235, Page(s) 199–210

    Abstract: ... ...

    Abstract Synotisjinpingensis
    Language English
    Publishing date 2023-11-20
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2579891-1
    ISSN 1314-2003 ; 1314-2011
    ISSN (online) 1314-2003
    ISSN 1314-2011
    DOI 10.3897/phytokeys.235.112230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Morphological and molecular analyses reveal two new species of

    Tang, Song-Ming / Vadthanarat, Santhiti / He, Jun / Raghoonundon, Bhavesh / Yu, Feng-Ming / Karunarathna, Samantha C / Li, Shu-Hong / Raspé, Olivier

    MycoKeys

    2023  Volume 95, Page(s) 61–82

    Abstract: Two new species, ...

    Abstract Two new species,
    Language English
    Publishing date 2023-02-08
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2630648-7
    ISSN 1314-4049 ; 1314-4049
    ISSN (online) 1314-4049
    ISSN 1314-4049
    DOI 10.3897/mycokeys.95.97156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Associations of Indoxyl Sulfate and p-cresyl Sulfate with Serum Uncarboxylated Matrix γ-carboxyglutamate Protein in Chronic Kidney Disease Patients.

    Tang, Xiaofang / Liu, Di / Xia, Ming / Liu, Yu / Liu, Hong

    Current medicinal chemistry

    2024  

    Abstract: Background: Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are two important protein-bound uremic retention solutes. Increased serum levels of IS and PCS are associated with cardiovascular calcification. Matrix γ-carboxyglutamate protein (MGP) is a ... ...

    Abstract Background: Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are two important protein-bound uremic retention solutes. Increased serum levels of IS and PCS are associated with cardiovascular calcification. Matrix γ-carboxyglutamate protein (MGP) is a potent inhibitor of vascular calcification and inactivated uncarboxylated MGP (ucMGP) is related to vascular calcification. Nevertheless, whether serum levels of IS and PCS are associated with the serum ucMGP level in chronic kidney disease (CKD) patients with different stages is unknown.
    Method: This cross-sectional study enrolled 90 patients in different stages of chronic kidney disease. Serum levels of IS and PCS were determined. The serum concentration of ucMGP was measured with an enzyme-linked immunosorbent assay. Independent associations between serum total IS and PCS with ucMGP were evaluated.
    Results: The mean serum level of ucMGP in participants of this study is 10.78±5.22 μg/mL. Serum levels of the two above-mentioned uremic toxins and ucMGP were elevated commensurately with deteriorating renal function. The serum level of ucMPG was associated with total IS (r = 0.456, p < 0.001) and total PCS (r =0.413, p < 0.001) levels. Multiple linear regression analysis showed that ucMGP was significantly related to levels of IS (β = 0.442, p <0.001), but not the level of PCS concentrations after adjusting for other confounding variables.
    Conclusion: Our study showed that a higher serum IS level was independently associated with ucMGP in deteriorating CKD. Therefore, it would be worthwhile to investigate the effect of IS on ucMGP in the pathogenesis of vascular calcification in future studies.
    Language English
    Publishing date 2024-01-12
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 1319315-6
    ISSN 1875-533X ; 0929-8673
    ISSN (online) 1875-533X
    ISSN 0929-8673
    DOI 10.2174/0109298673272856231225173757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling.

    Gu, Ming / Chen, Yu-Jun / Feng, Ya-Ru / Tang, Zhi-Peng

    Chinese medicine

    2024  Volume 19, Issue 1, Page(s) 41

    Abstract: Background: LanGui tea, a traditional Chinese medicine formulation comprising of Gynostemma pentaphyllum (Thunb.) Makino, Cinnamomum cassia (L.) J. Presl, and Ampelopsis grossedentata (Hand-Mazz) W.T. Wang, has yet to have its potential contributions to ...

    Abstract Background: LanGui tea, a traditional Chinese medicine formulation comprising of Gynostemma pentaphyllum (Thunb.) Makino, Cinnamomum cassia (L.) J. Presl, and Ampelopsis grossedentata (Hand-Mazz) W.T. Wang, has yet to have its potential contributions to alcoholic liver disease (ALD) fully elucidated. Consequently, the objective of this research is to investigate the protective properties of LanGui tea against binge alcohol-induced ALD and the mechanisms underlying its effects.
    Methods: An experimental model of acute alcohol-induced liver disease was performed to assess the protective effects of extract of LanGui tea (ELG) at both 50 and 100 mg.kg
    Results: ELG demonstrated a mitigating effect on fatty liver, inflammation, and hepatic dysfunction within the mouse model. This effect was achieved by activating AMPK signaling and inhibitingNLRP3 signaling in the liver, causing a reduction in IL-1β generation. In vitro studies further confirmed that ELG inhibited cell damage and IL-1β production in ethanol-induced hepatocytes by enhancing AMPK-NLRP3 signaling. Conversely, the pharmacological inhibition of AMPK activity nearly abrogated such alteration.
    Conclusions: Thus, LanGui tea emerges as a promising herbal therapy for ALD management involving AMPK-NLRP3 signaling.
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2260322-0
    ISSN 1749-8546
    ISSN 1749-8546
    DOI 10.1186/s13020-024-00906-0
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  10. Article ; Online: Ocular dominance-dependent binocular combination of monocular neuronal responses in macaque V1.

    Zhang, Sheng-Hui / Zhao, Xing-Nan / Jiang, Dan-Qing / Tang, Shi-Ming / Yu, Cong

    eLife

    2024  Volume 13

    Abstract: Primates rely on two eyes to perceive depth, while maintaining stable vision when either one eye or both eyes are open. Although psychophysical and modeling studies have investigated how monocular signals are combined to form binocular vision, the ... ...

    Abstract Primates rely on two eyes to perceive depth, while maintaining stable vision when either one eye or both eyes are open. Although psychophysical and modeling studies have investigated how monocular signals are combined to form binocular vision, the underlying neuronal mechanisms, particularly in V1 where most neurons exhibit binocularity with varying eye preferences, remain poorly understood. Here, we used two-photon calcium imaging to compare the monocular and binocular responses of thousands of simultaneously recorded V1 superficial-layer neurons in three awake macaques. During monocular stimulation, neurons preferring the stimulated eye exhibited significantly stronger responses compared to those preferring both eyes. However, during binocular stimulation, the responses of neurons preferring either eye were suppressed on the average, while those preferring both eyes were enhanced, resulting in similar neuronal responses irrespective of their eye preferences, and an overall response level similar to that with monocular viewing. A neuronally realistic model of binocular combination, which incorporates ocular dominance-dependent divisive interocular inhibition and binocular summation, is proposed to account for these findings.
    MeSH term(s) Animals ; Dominance, Ocular ; Eye ; Vision, Binocular ; Macaca ; Neurons
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.92839
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