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  1. Book ; Online ; Thesis: Multiparametrische MRT und MRT-gestützte Biopsie bei Patienten mit Prostatakarzinomverdacht

    Egbers, Nina [Verfasser]

    Nachweisgenauigkeit und Akzeptanz der MRT-gestützten Biopsie

    2016  

    Author's details Nina Egbers
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Medizinische Fakultät Charité - Universitätsmedizin Berlin
    Publishing place Berlin
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Article ; Online: MRI-guided core needle biopsy of the prostate: acceptance and side effects.

    Egbers, Nina / Schwenke, Carsten / Maxeiner, Andreas / Teichgräber, Ulf / Franiel, Tobias

    Diagnostic and interventional radiology (Ankara, Turkey)

    2015  Volume 21, Issue 3, Page(s) 215–221

    Abstract: Purpose: We aimed to study side effects, complications, and patient acceptance of magnetic resonance imaging-guided real-time biopsy (MRI-GB) of the prostate.: Methods: Fifty-four men (49-78 years) with elevated prostate-specific antigen after at ... ...

    Abstract Purpose: We aimed to study side effects, complications, and patient acceptance of magnetic resonance imaging-guided real-time biopsy (MRI-GB) of the prostate.
    Methods: Fifty-four men (49-78 years) with elevated prostate-specific antigen after at least one negative systematic transrectal ultrasound-guided biopsy (TRUS-GB) were included in a prospective clinical study. Suspicious areas on images were selectively sampled by obtaining a median of four specimens (range, 1-9 specimens) using MRI-GB. In TRUS-GB, a median of 10 specimens (range, 6-14 specimens) were obtained. Telephone interviews were conducted one week after outpatient MRI-GB, asking patients about pain and side effects (hematuria, hemospermia, rectal bleeding, fever, and chills) of the two biopsy procedures and which of the two procedures they preferred. Multinomial regression analysis and Fisher's exact test was used to test for differences.
    Results: MRI-GB was preferred by 65% (35/54), and 82% (44/54) would undergo MRI-GB again. Pain intensity (P = 0.005) and bleeding duration (P = 0.004) were significantly lower for MRI-GB compared with TRUS-GB. Hematuria was less common after MRI-GB compared with TRUS-GB (P = 0.006). A high correlation was given between bleeding intensity and bleeding duration for TRUS-GB (r=0.77) and pain intensity and pain duration for MRI-GB (r=0.65). Although hemospermia, rectal hemorrhage, fever, and chills were less common in MRI, they showed no statistically significant difference.
    Conclusion: MRI-GB of the prostate seems to have fewer side effects and less pain intensity than TRUS-GB and was preferred by the majority of patients.
    MeSH term(s) Aged ; Biopsy, Large-Core Needle/adverse effects ; Biopsy, Large-Core Needle/methods ; Humans ; Image-Guided Biopsy/adverse effects ; Image-Guided Biopsy/methods ; Kallikreins/blood ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Patient Preference ; Prospective Studies ; Prostate/diagnostic imaging ; Prostate/pathology ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/pathology ; Regression Analysis ; Surveys and Questionnaires ; Ultrasonography, Interventional/adverse effects ; Ultrasonography, Interventional/methods
    Chemical Substances KLK3 protein, human (EC 3.4.21.-) ; Kallikreins (EC 3.4.21.-) ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2015-04-18
    Publishing country Turkey
    Document type Clinical Trial ; Journal Article
    ZDB-ID 2184145-7
    ISSN 1305-3612 ; 1305-3612
    ISSN (online) 1305-3612
    ISSN 1305-3612
    DOI 10.5152/dir.2014.14372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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