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  1. Article ; Online: CT and MRI of Gastrointestinal Stromal Tumors: New Trends and Perspectives.

    Barat, Maxime / Pellat, Anna / Dohan, Anthony / Hoeffel, Christine / Coriat, Romain / Soyer, Philippe

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2023  Volume 75, Issue 1, Page(s) 107–117

    Abstract: ... of the gastrointestinal tract that express positivity for CD117, which is a c- ...

    Abstract Gastrointestinal stromal tumors (GISTs) are defined as mesenchymal tumors of the gastrointestinal tract that express positivity for CD117, which is a c-
    MeSH term(s) Humans ; Gastrointestinal Stromal Tumors ; Artificial Intelligence ; Leiomyoma ; Tomography, X-Ray Computed ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-06-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/08465371231180510
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Stomach size in anorexia nervosa: A new challenge?

    Joyeux, Marie-Alix / Pierre, Antoine / Barrois, Marion / Hoeffel, Christine / Devie, Antoine / Brugel, Mathias / Bertin, Eric

    European eating disorders review : the journal of the Eating Disorders Association

    2024  

    Abstract: Background & aims: Changes in stomach size may impact eating behaviour. A recent study showed gastric dilatation in restrictive eating disorders using computed tomography scans. This study aimed to describe stomach size in the standing position in women ...

    Abstract Background & aims: Changes in stomach size may impact eating behaviour. A recent study showed gastric dilatation in restrictive eating disorders using computed tomography scans. This study aimed to describe stomach size in the standing position in women with anorexia nervosa (AN).
    Methods: Women treated for AN at our institution were retrospectively included if they had undergone upper gastrointestinal radiography (UGR) after the diagnosis of AN. Two control groups (CG1 and CG2) were included, both comprising female patients: CG1 patients were not obese and underwent UGR for digestive symptoms of other aetiologies, and CG2 comprised obese individuals who had UGR before bariatric surgery. A UGR-based Stomach Size Index (SSI), calculated as the ratio of the length of the stomach to the distance between the upper end of the stomach and the top of the iliac crests, was measured in all three groups. Gastromegaly was defined as SSI >1.00.
    Results: 45 patients suffering from AN (28 with restrictive and 17 with binge/purge subtype), 10 CG1 and 20 CG2 subjects were included in this study. Stomach Size Index was significantly higher in AN (1.27 ± 0.24) than in CG1 (0.80 ± 0.11) and CG2 (0.68 ± 0.09); p < 0.001, but was not significantly different between patients with the restrictive and binge/purge subtypes. Gastromegaly was present in 82.2% of patients with AN and not present in the control groups. In patients with AN, gastromegaly was present in 12/15 patients without digestive symptoms (80.0%) and in 25/30 patients with digestive complaints (83.3%) at time of UGR (p = 0.99). In the AN group, no significant relationship was found between SSI and body mass index.
    Conclusion: Gastromegaly is frequent in AN and could influence AN recovery. This anatomical modification could partially explain the alterations of gastric motility previously reported in AN.
    Language English
    Publishing date 2024-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1159507-3
    ISSN 1099-0968 ; 1067-1633 ; 1072-4133
    ISSN (online) 1099-0968
    ISSN 1067-1633 ; 1072-4133
    DOI 10.1002/erv.3089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cerebellum/liver index in pretherapeutic 18F-FDG PET/CT as a predictive marker of progression-free survival in follicular lymphoma treated by immunochemotherapy and rituximab maintenance.

    Godard, François / Durot, Eric / Durot, Carole / Hoeffel, Christine / Delmer, Alain / Morland, David

    Medicine

    2022  Volume 101, Issue 5, Page(s) e28791

    Abstract: Abstract: The purpose of this study was to investigate the value of the "cerebellum/ liver index for prognosis" (CLIP) as a new prognostic marker in pretherapeutic 18F-Fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with ... ...

    Abstract Abstract: The purpose of this study was to investigate the value of the "cerebellum/ liver index for prognosis" (CLIP) as a new prognostic marker in pretherapeutic 18F-Fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with follicular lymphoma treated by immunochemotherapy and rituximab maintenance, focusing on progression-free survival (PFS).Clinicobiological and imaging data from patients with follicular lymphoma between March 2010 and September 2015 were retrospectively collected and 5-year PFS was determined. The conventional PET parameters (maximum standardized uptake value and total metabolic tumor volume) and the CLIP, corresponding to the ratio of the cerebellum maximum standardized uptake value over the liver SUVmean, were extracted from the pretherapeutic 18F-FDG PET.Forty-six patients were included. Eighteen patients (39%) progressed within the 5 years after treatment initiation. Five-year PFS was 78.6% when CLIP was >4.0 and 42.0% when CLIP was <4.0 (P = .04). CLIP was a significant predictor of PFS on univariate analysis (hazard ratio 3.1, P = .049) and was near-significant on multivariate analysis (hazard ratio 2.8, P = .07) with ECOG PS as a cofactor.The CLIP derived from pretherapeutic 18F-FDG PET seems to be an interesting predictive marker of PFS in follicular lymphoma treated by immunochemotherapy and rituximab maintenance. These results should be evaluated prospectively in a larger cohort.
    MeSH term(s) Biomarkers ; Cerebellum/diagnostic imaging ; Fluorodeoxyglucose F18 ; Humans ; Immunotherapy ; Liver/diagnostic imaging ; Lymphoma, Follicular/diagnostic imaging ; Lymphoma, Follicular/drug therapy ; Positron Emission Tomography Computed Tomography ; Prognosis ; Progression-Free Survival ; Radiopharmaceuticals ; Retrospective Studies ; Rituximab/therapeutic use
    Chemical Substances Biomarkers ; Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2022-02-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000028791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gender diversity in authorship in Diagnostic & Interventional Imaging: Where are we now?

    Soyer, Philippe / Revel, Marie-Pierre / Dohan, Anthony / Vernhet-Kovacsik, Hélène / Nougaret, Stéphanie / Hoeffel, Christine

    Diagnostic and interventional imaging

    2022  Volume 103, Issue 5, Page(s) 237–239

    MeSH term(s) Authorship ; Bibliometrics ; Humans ; Publishing
    Language English
    Publishing date 2022-02-17
    Publishing country France
    Document type Editorial ; Comment
    ZDB-ID 2648283-6
    ISSN 2211-5684 ; 2211-5684
    ISSN (online) 2211-5684
    ISSN 2211-5684
    DOI 10.1016/j.diii.2022.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pretreatment CT Texture Parameters as Predictive Biomarkers of Progression-Free Survival in Follicular Lymphoma Treated with Immunochemotherapy and Rituximab Maintenance.

    Durot, Carole / Durot, Eric / Mulé, Sébastien / Morland, David / Godard, François / Quinquenel, Anne / Delmer, Alain / Soyer, Philippe / Hoeffel, Christine

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 13

    Abstract: The purpose of this study was to determine whether texture analysis features present on pretreatment unenhanced computed tomography (CT) images, derived from 18F-fluorodeoxyglucose positron emission/computed tomography (18-FDG PET/CT), can predict ... ...

    Abstract The purpose of this study was to determine whether texture analysis features present on pretreatment unenhanced computed tomography (CT) images, derived from 18F-fluorodeoxyglucose positron emission/computed tomography (18-FDG PET/CT), can predict progression-free survival (PFS), progression-free survival at 24 months (PFS 24), time to next treatment (TTNT), and overall survival in patients with high-tumor-burden follicular lymphoma treated with immunochemotherapy and rituximab maintenance. Seventy-two patients with follicular lymphoma were retrospectively included. Texture analysis was performed on unenhanced CT images extracted from 18-FDG PET/CT examinations that were obtained within one month before treatment. Skewness at a fine texture scale (SSF = 2) was an independent predictor of PFS (hazard ratio = 3.72 (95% CI: 1.15, 12.11),
    Language English
    Publishing date 2023-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13132237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Three-Dimensional Measurement of the Uterus on Magnetic Resonance Images: Development and Performance Analysis of an Automated Deep-Learning Tool.

    Mulliez, Daphné / Poncelet, Edouard / Ferret, Laurie / Hoeffel, Christine / Hamet, Blandine / Dang, Lan Anh / Laurent, Nicolas / Ramette, Guillaume

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 16

    Abstract: Uterus measurements are useful for assessing both the treatment and follow-ups of gynaecological patients. The aim of our study was to develop a deep learning (DL) tool for fully automated measurement of the three-dimensional size of the uterus on ... ...

    Abstract Uterus measurements are useful for assessing both the treatment and follow-ups of gynaecological patients. The aim of our study was to develop a deep learning (DL) tool for fully automated measurement of the three-dimensional size of the uterus on magnetic resonance imaging (MRI). In this single-centre retrospective study, 900 cases were included to train, validate, and test a VGG-16/VGG-11 convolutional neural network (CNN). The ground truth was manual measurement. The performance of the model was evaluated using the objective key point similarity (OKS), the mean difference in millimetres, and coefficient of determination R
    Language English
    Publishing date 2023-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13162662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: CT and MRI of abdominal cancers: current trends and perspectives in the era of radiomics and artificial intelligence.

    Barat, Maxime / Pellat, Anna / Hoeffel, Christine / Dohan, Anthony / Coriat, Romain / Fishman, Elliot K / Nougaret, Stéphanie / Chu, Linda / Soyer, Philippe

    Japanese journal of radiology

    2023  Volume 42, Issue 3, Page(s) 246–260

    Abstract: Abdominal cancers continue to pose daily challenges to clinicians, radiologists and researchers. These challenges are faced at each stage of abdominal cancer management, including early detection, accurate characterization, precise assessment of tumor ... ...

    Abstract Abdominal cancers continue to pose daily challenges to clinicians, radiologists and researchers. These challenges are faced at each stage of abdominal cancer management, including early detection, accurate characterization, precise assessment of tumor spread, preoperative planning when surgery is anticipated, prediction of tumor aggressiveness, response to therapy, and detection of recurrence. Technical advances in medical imaging, often in combination with imaging biomarkers, show great promise in addressing such challenges. Information extracted from imaging datasets owing to the application of radiomics can be used to further improve the diagnostic capabilities of imaging. However, the analysis of the huge amount of data provided by these advances is a difficult task in daily practice. Artificial intelligence has the potential to help radiologists in all these challenges. Notably, the applications of AI in the field of abdominal cancers are expanding and now include diverse approaches for cancer detection, diagnosis and classification, genomics and detection of genetic alterations, analysis of tumor microenvironment, identification of predictive biomarkers and follow-up. However, AI currently has some limitations that need further refinement for implementation in the clinical setting. This review article sums up recent advances in imaging of abdominal cancers in the field of image/data acquisition, tumor detection, tumor characterization, prognosis, and treatment response evaluation.
    MeSH term(s) Humans ; Radiomics ; Artificial Intelligence ; Magnetic Resonance Imaging ; Abdominal Neoplasms/diagnostic imaging ; Biomarkers ; Tomography, X-Ray Computed ; Tumor Microenvironment
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-11-06
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 2488907-6
    ISSN 1867-108X ; 1867-1071
    ISSN (online) 1867-108X
    ISSN 1867-1071
    DOI 10.1007/s11604-023-01504-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Differentiation between adrenocortical carcinoma and lipid-poor adrenal adenoma using a multiparametric MRI-based diagnostic algorithm.

    Oloukoi, Carmelia / Dohan, Anthony / Gaillard, Martin / Hoeffel, Christine / Groussin-Rouiller, Lionel / Bertherat, Jérome / Jouinot, Anne / Assié, Guillaume / Fuks, David / Sibony, Mathilde / Soyer, Philippe / Jannot, Anne-Sophie / Barat, Maxime

    Diagnostic and interventional imaging

    2024  

    Abstract: Purpose: The purpose of this study was to evaluate the capabilities of multiparametric magnetic resonance imaging (MRI) in differentiating between lipid-poor adrenal adenoma (LPAA) and adrenocortical carcinoma (ACC).: Materials and methods: Patients ... ...

    Abstract Purpose: The purpose of this study was to evaluate the capabilities of multiparametric magnetic resonance imaging (MRI) in differentiating between lipid-poor adrenal adenoma (LPAA) and adrenocortical carcinoma (ACC).
    Materials and methods: Patients of two centers who underwent surgical resection of LPAA or ACC after multiparametric MRI were retrospectively included. A training cohort was used to build a diagnostic algorithm obtained through recursive partitioning based on multiparametric MRI variables, including apparent diffusion coefficient and chemical shift signal ratio (i.e., tumor signal intensity index). The diagnostic performances of the multiparametric MRI-based algorithm were evaluated using a validation cohort, alone first and then in association with adrenal tumor size using a cut-off of 4 cm. Performances of the diagnostic algorithm for the diagnosis of ACC vs. LPAA were calculated using pathology as the reference standard.
    Results: Fifty-four patients (27 with LPAA and 27 with ACC; 37 women; mean age, 48.5 ± 13.3 [standard deviation (SD)] years) were used as the training cohort and 61 patients (24 with LPAA and 37 with ACC; 47 women; mean age, 49 ± 11.7 [SD] years) were used as the validation cohort. In the validation cohort, the diagnostic algorithm yielded best accuracy for the diagnosis of ACC vs. LPAA (75%; 46/61; 95% CI: 55-88) when used without lesion size. Best sensitivity was obtained with the association of the diagnostic algorithm with tumor size (96%; 23/24; 95% CI: 80-99). Best specificity was obtained with the diagnostic algorithm used alone (76%; 28/37; 95% CI: 60-87).
    Conclusion: A multiparametric MRI-based diagnostic algorithm that includes apparent diffusion coefficient and tumor signal intensity index helps discriminate between ACC and LPAA with high degrees of specificity and accuracy. The association of the multiparametric MRI-based diagnostic algorithm with adrenal lesion size helps maximize the sensitivity of multiparametric MRI for the diagnosis of ACC.
    Language English
    Publishing date 2024-04-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 2648283-6
    ISSN 2211-5684 ; 2211-5684
    ISSN (online) 2211-5684
    ISSN 2211-5684
    DOI 10.1016/j.diii.2024.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Vanishing Bone Metastases in 18F-FDG PET/CT.

    Ainouche, Alida / Morland, David / Durot, Carole / Hoeffel, Christine / Papathanassiou, Dimitri

    Clinical nuclear medicine

    2020  Volume 45, Issue 7, Page(s) 559–560

    Abstract: A 36-year-old woman with a history of large B-cell lymphoma was referred for the exploration of sclerotic bone thoracic vertebral metastases discovered on a contrast-enhanced CT examination. F-FDG PET showed no pathological uptake in the affected ... ...

    Abstract A 36-year-old woman with a history of large B-cell lymphoma was referred for the exploration of sclerotic bone thoracic vertebral metastases discovered on a contrast-enhanced CT examination. F-FDG PET showed no pathological uptake in the affected vertebrae, as well as normal vertebral density on the coupled unenhanced CT. After review of the initial contrast-enhanced CT, a left brachiocephalic vein stenosis was noted, leading to a retrograde contrast filling of the accessory hemiazygos vein and the capillary spaces within the vertebrae, mimicking sclerotic metastases.
    MeSH term(s) Adult ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/secondary ; Female ; Fluorodeoxyglucose F18 ; Humans ; Lymphoma, Large B-Cell, Diffuse/pathology ; Positron Emission Tomography Computed Tomography ; Thoracic Vertebrae/diagnostic imaging
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000003089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Diagnosis of postoperative recurrence of Crohn disease with MR-enterography: Value of diffusion-weighted imaging.

    Djelouah, Manel / Marical, Victoria / Kanagaratnam, Lukshe / Kianmanesh, Reza / Biron, Amélie / Cadiot, Guillaume / Hoeffel, Christine

    Diagnostic and interventional imaging

    2021  Volume 102, Issue 12, Page(s) 743–751

    Abstract: Purpose: To compare the diagnostic capabilities of MR enterography (MRE) using contrast-enhanced (CE) sequences with those of MRE using diffusion-weighted (DW) imaging for the diagnosis of postoperative recurrence at the neo-terminal ileum and/or ... ...

    Abstract Purpose: To compare the diagnostic capabilities of MR enterography (MRE) using contrast-enhanced (CE) sequences with those of MRE using diffusion-weighted (DW) imaging for the diagnosis of postoperative recurrence at the neo-terminal ileum and/or anastomosis after ileocolonic resection in patients with Crohn disease (CD), and to clarify the role of additional DW imaging to CE-MRE in this context.
    Material and methods: Forty patients who underwent ileal resection for CD, and both endoscopy and MRE within the first year after surgery were included. There were 21 men and 19 women, with a mean age of 38 years±12 (SD) years (range: 18-67 years). MRE examinations were blindly analyzed independently by one senior (R1) and one junior (R2) radiologist for the presence of small bowel postoperative recurrence at the anastomotic site. During a first reading session, T2-, steady-state- and DW-MRE were reviewed (DW-MRE or set 1). During a separate distant session, T2-, steady-state- and CE-MRE were reviewed (CE-MRE or set 2). Lastly, all sequences were analyzed altogether (set 3). Performances of each reader for the diagnosis of postoperative recurrence were evaluated using endoscopic findings as the standard of reference (Rutgeerts score≥i2b).
    Results: Fifteen patients out of 40 (37.5%) had endoscopic postoperative recurrence at the anastomotic site. Sensitivity for the diagnosis of postoperative recurrence was 73% (95% CI: 51-96%) for R1 and 67% (95% CI: 43-91%) for R2 using set 1, and 80% (95% CI: 60-100%) for both readers using set 2. There was no significant differences in sensitivity between reading set 1 and reading set 2, for either R1 or R2 (R1, P> 0.99; R2, P=0.48). Specificity was 96% (95% CI: 88-100%) for both readers using set 1 or using set 2. Reading set 3 yielded an area under the ROC curve (AUC) of 0.93 (95% CI: 0.84-1) versus 0.89 (95% CI: 0.75-1) with set 1 (P=0.18) and versus 0.89 (95% CI: 0.78-1) with set 2 (P=0.21). No significant differences in AUC were found between set 1 or 2 and set 3 (P=0.18), nor between set 1 and 2 (P=0.76). Accuracies were 88% (95% CI: 74-95%) and 85% (95% CI: 71-93%) for DW-MRE for R1 and R2, respectively; 90% (95% CI: 77-96%) for CE-MRE for both readers; and 93% (95% CI: 80-97%) and 88% (95% CI: 74-95%) for R1 and R2 with set 3, respectively.
    Conclusion: DW-MRE has diagnostic capabilities similar to those of CE-MRE for the diagnosis of postoperative recurrence of CD at the anastomotic site.
    MeSH term(s) Adult ; Crohn Disease/diagnostic imaging ; Crohn Disease/surgery ; Diffusion Magnetic Resonance Imaging ; Endoscopy, Gastrointestinal ; Female ; Humans ; Intestine, Small ; Intestines ; Magnetic Resonance Imaging ; Male
    Language English
    Publishing date 2021-06-18
    Publishing country France
    Document type Journal Article
    ZDB-ID 2648283-6
    ISSN 2211-5684 ; 2211-5684
    ISSN (online) 2211-5684
    ISSN 2211-5684
    DOI 10.1016/j.diii.2021.06.002
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